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Association of CFH and MAP1LC3B gene polymorphisms with age-related macular degeneration in a high-altitude population

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International Journal of Ophthalmology(English edition) 2022年第11期15卷 1752-1756页

作者： Rui-juan Guan Xin Yan Ling Li Ze-Feng Kang Xiao-Ying Zhang huan-juan yang Soochow University Suzhou 215000Jiangsu ProvinceChina Department of Ophthalmology Qinghai Provincial People's HospitalXining 810007Qinghai ProvinceChina Eye Hospital China Academy of Chinese Medical SciencesBeijing 100043China

AIM: To evaluate the association of complement factor H(CFH) and microtubule-associated protein 1 light chain 3 beta(MAP1LC3B) gene polymorphisms with the risk of age-related macular degeneration(AMD) in a high-altitude population. METHODS: The study group consisted of 172 participants with symptoms of AMD who were examined and diagnosed between January 2019 and June 2020. The control group was composed of 120 healthy individuals. Each participant was required to provide two milliliters of peripheral blood for DNA extraction. Two single nucleotide polymorphisms(SNPs) of CFH(rs1061170 and rs800292) and two SNPs of MAP1LC3B(rs8044820 and rs9903) were genotyped. The genotypes and allele frequencies of the SNPs in the study and control groups were further compared using Chi-square and Fisher’s exact tests. RESULTS: In a high-altitude population, the nominally significant differences of rs800292 and rs9903’s genotype AG frequencies were observed in the AMD group(P=0.034 and 0.004, respectively). The frequencies of allele G of rs800292 and allele A of rs9903 were also significantly dif ferent in the AMD group compared to the control [(P=0.034, OR=0.70, 95%CI: 0.50-0.98) and(P=0.004, OR=1.60, 95%CI: 1.15-2.22), respectively]. No significant differences in the genotype distributions(P=0.16 and 0.40, respectively) and allele frequencies(P>0.05) of rs1061170 and rs8044820 were observed in the AMD ***: Genotype AG of rs800292 may be a protective factor for AMD. Conversely, rs9903 seems to be a risk factor for AMD. Therefore, allele G of rs800292 may be a protective factor, and allele A of rs9903, a risk factor for AMD in Qinghai high-altitude population.

关键词： age-related macular degeneration complement factor H microtubule-associated protein 1 light chain 3 beta single nucleotide polymorphisms pathogenesis

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基于文献计量的植物雌雄异株研究进展

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广西植物 2017年第5期37卷 661-674页

作者：严欢欢肖娟杨永清重庆师范大学生命科学学院植物环境适应分子生物学重庆市重点实验室重庆401331

雌雄异株植物是研究植物性别的理想材料,同时作为生态系统的重要组成部分,对生物多样性的维持与保护起着重要作用。该文从文献计量学角度综述了雌雄异株植物相关研究的进展。通过检索Web of Science(WOS)平台的SCI-E数据库和CNKI数据库... 详细信息

雌雄异株植物是研究植物性别的理想材料,同时作为生态系统的重要组成部分,对生物多样性的维持与保护起着重要作用。该文从文献计量学角度综述了雌雄异株植物相关研究的进展。通过检索Web of Science(WOS)平台的SCI-E数据库和CNKI数据库的有关雌雄异株研究的文献数据,从文献年代分布、期刊分布、研究国家与机构、核心作者和高引论文等方面进行了分析,并借助CitespaceⅢ信息可视化软件绘制雌雄异株植物研究的科学知识图谱,总结了雌雄异株研究的热点和前沿。结果表明:WOS数据库中,雌雄异株植物研究呈现快速上升趋势,就发文总量来看,发文前五的国家为美国、日本、加拿大、英格兰和中国。其中,美国发文量占比为31.03%;中国科学院为发文量最多的机构,发文占比3.36%,其次为牛津大学(2.613%),多伦多大学位列第三(2.427%);中国,巴西和印度三国,西班牙马萨里克大学和北京林业大学两个研究机构近5年来在该领域发文增量较快。论文主要集中在植物科学、环境科学与生态学和遗传学等学科。载文量前十位的期刊累计载文占比高达24.13%,发文量最多的期刊为American Journal of Botany,占总发文量的6.07%,其次为Evolution(2.80%),Annals of Botany(2.52%)排名第三。发文最多的作者为捷克科学院的VYSKOT B,发文占总数的2.57%,高引论文大多出自美国学者之手。从CNKI数据库看,西华师范大学、北京林业大学和河南师范大学发文数量位列前三,发文量最高的期刊为《生命世界》,占总发文量的3.00%。综合Web of Science和CNKI两大数据库的文献来看,青杨和番木瓜作为研究雌雄异株植物的模式植物,近年发文较多。当前的研究热点主要集中在雌雄性别决定,繁殖代价,雌雄个体对环境因子的响应差异等方面。

关键词：雌雄异株文献计量分析 Web of Science CNKI Citespace III

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Controlled synthesis of GeSe_(2) and GeSe nanostructures induced by TBAB

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Rare Metals 2023年第1期42卷 189-197页

作者： huan yang Yue Wu Li-Yan Hu juan-juan Wang Fang Wang Xiao-Hong Xu School of Chemistry and Materials Science of Shanxi Normal University and Key Laboratory of Magnetic Molecules and Magnetic Information Materials of Ministry of Education Taiyuan031000China Research Institute of Materials Science of Shanxi Normal University and Collaborative Innovation Center for Advanced Permanent Magnetic Materials and Technology of Ministry of Education Taiyuan031000China

Ge-based selenides have attracted extensive attention as promising candidates for future optoelectronic *** great progress has been achieved,the controlled synthesis of GeSe2and GeSe nanostructures and understanding the relative growth mechanisms of them are still ***,monodispersed GeSe_(2) nanoflowers with a diameter of~4μm and highly uniform GeSe nanoparticles with a lateral size of~100 nm are presented by using a colloidal synthetic *** is found that borane tert-butylamine complex(TBAB)plays an important role in determining the Ge-Se crystal phases due to its moderately ***,the coexistence of GeSe_(2) and GeSe phases can also be acquired by precisely controlling the amount of *** brief,this work provides both new insights of the phase control of Gebased selenides by liquid-phase method and a practical means of producing well-controlled germanium selenide nanostructures.

关键词： GeSe_(2) GeSe Borane tert-butylamine complex(TBAB) Liquid-phase method Bandgaps

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Fabrication and analysis of TIG welding-brazing butt joints of in-situ TiB2/7050 composite and TA2

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Defence Technology（防务技术） 2021年第3期17卷 1062-1070页

作者： huan-huan Sun Yi-bo Ren yang Feng Hao-qiang Ba Dong Chen Chun-juan Xia Hao-wei Wang School of Materials Science&Engineering Shenyang Ligong UniversityShenyangChina School of Materials Science&Engineering Shanghai Jiao Tong UniversityShanghaiChina

Lightweight hybrid structures of Al MMCs and titanium alloy dissimilar materials have great prospect in the defence industry application. So, it is necessary to join Al MMCs with Ti metal to achieve this structural design. In this work, in-situ Ti B_(2)/7050 composite and TA2 were firstly attempted to join by TIG welding-brazing technique. The result was that the intact welding-brazing butt joint was successfully fabricated. The joint presents dual characteristics, being a brazing on TA2 side and a welding on Ti B_(2)/7050 side. At brazing joint side, ER4043 filler metal effectively wets on TA2 under TIG heating condition,and a continuous interfacial reaction layer with 1 e3 mm is formed at welded metal/TA2 interface. The whole interfacial reaction layers are composed of Ti(Al Si)3 intermetallic compounds(IMCs), but their morphologies at the different regions present obvious distinguishes. The microhardness of the reaction layers is as much as 141 e190 HV. At welding joints side, the fusion zone appears the equixaed crystal structure, and the grain sizes are much smaller than those of welded metal, which is attributed to the effect of Ti B2 particulates from the melted Ti B_(2)/7050 on acceleration formation and inhibiting growth for the new crystal nucleus. The tensile test results show that average tensile strength of the optimal welding-brazing joint is able to achieve 138 MPa. The failure of the tensile joint occurs by quasi-cleavage pattern, and the cracks initiate from the IMCs layer at the groove surface of TA2 and propagate into the welded metal.

关键词： In-situ TiB2/7050 composite TA2 TIG welding-brazing Fabrication Analysis

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Mechanically Robust Polylactide Fibers with Super Heat Resistance via Constructing in situ Nanofibrils

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Chinese Journal of Polymer Science 2023年第6期41卷 962-971,I0011页

作者： Jun Lu Li-Xiang Yi Yong-huan Zhao yang Meng Peng-Xiang Yu juan-juan Su Jian Han College of Materials and Textiles Zhejiang Sci-Tech UniversityHangzhou 310018China The Key Lab of Industrial Textile Material and Manufacturing Technology Zhejiang ProvinceZhejiang Sci-Tech UniversityHangzhou 310018China

All-PLA fibers with excellent comprehensive performance and recycling convenience are realized *** molecular weight poly(D-lactide)(HPDLA)is incorporated into poly(L-lactide)(PLLA)matrix to construct in situ nanofibrils structure by taking advantages of the microphase separation between HPDLA and *** tensile strength of HPDLA/PLLA composite fibers(HDL-8)is enhanced from 2.1 cN/dtex of neat PLLA-8 fibers up to 2.9 cN/*** boiling water shrinkage(BWS)and shrinkage in hot air(HAS)significantly decrease to 7.8%and 2.8%,*** abundance of in situ nanofibrils creates a grille-like structure that is crucial for both heat and hydrolysis *** strikingly,a hybrid shish-kebab structure induced by the in situ nanofibrils serves as a mechanical *** work paves a new way for heat resistance and self-reinforcement modification of PLA materials.

关键词： materials. fibers lactide

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Optimization of Wind Farm Collection Line Structure under Symmetrical Grid Fault

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Chinese Journal of Electrical Engineering 2019年第3期5卷 49-58页

作者： huan Jin Xueyi Zhang yang Zhang Qianghui Xiao juan Li Ya Liu Hunan University of Technology Zhuzhou 412007China

A power-transmission collection line is connected to each wind turbine of a wind farm and then connected to the incoming switchgear at the low-voltage side of the booster station at a certain ***,the grouping of the wind turbines in the wind farm determines the layout of the lines and affects the line *** line structure and composition of the wind farm are analyzed,and the relationship between the impedance of the collection line and reactive power generated by the wind turbine at low-voltage ride through is *** conclude that the smaller the equivalent impedance of the wind farm collection line structure is,the greater the reactive power at the wind farm collection line point *** addition,the economic aspect of the collection line needs to be considered in the *** economic aspect and impedance values have contrasting ***,according to the condition of minimum impedance and optimized economic aspect,an optimization model of a wind-farm collector-circuit structure is *** optimal structure of the wind farm collector circuit is calculated using the Monte Carlo method,and the theoretical analysis is verified by simulation.

关键词： Wind farm symmetrical grid fault collection line optimization model

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用WO_3+C纳米混合粉末制备堆焊用新型耐磨合金粉块

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稀有金属与硬质合金 2003年第3期31卷 5-8页

作者：陈春焕赵绣娟杨德新大连铁道学院材料科学与工程系辽宁大连116028

以纳米级的WO3+C混合粉末制备新型耐磨合金粉块,对该粉块进行了工艺性试验,并对堆焊层的组织、成分及硬度等进行了分析。试验结果表明:该粉块焊接工艺性良好,熔敷效率高;堆焊层组织细小,主要为富W碳化物(Fe6W6C)、针状马氏体和奥氏体,... 详细信息

以纳米级的WO3+C混合粉末制备新型耐磨合金粉块,对该粉块进行了工艺性试验,并对堆焊层的组织、成分及硬度等进行了分析。试验结果表明:该粉块焊接工艺性良好,熔敷效率高;堆焊层组织细小,主要为富W碳化物(Fe6W6C)、针状马氏体和奥氏体,堆焊层中未有WC相形成。焊后堆焊层硬度在HRC60以上,最高可达HRC63。和微米级粉末相比,纳米粉末制备的粉块基体中的含W量高,组织细小,硬度高,适于耐磨堆焊。

关键词： WO3+C 纳米粉末合金粉块堆焊

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A new phenolic lactone from the bark of Phellodendron chinense

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Chinese Chemical Letters 2009年第8期20卷 958-960页

作者： Xue Hu Li Wen juan Zhang huan yang Qi Yan Ping Shi Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical PhysicsChinese Academy of Sciences Lanzhou 730000 China The Graduate University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 100039 China

A new phenolic lactone, named phellolactone （1） was isolated from the bark of Phellodendron chinense Schneid and its structure was elucidated by means of extensively spectroscopic methods, including IR, UV, HRESI-MS and NMR techniques. ？2009 Yah Ping Shi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： PheUodendron chinense Rutaceac Phellolactone

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Fuzzy PID Control of Space Manipulator for Both Ground Alignment and Space Applications

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International Journal of Automation and computing 2014年第4期11卷 353-360页

作者： Fu-Cai Liu Li-huan Liang juan-juan Gao Key Lab of Industrial Computer Control of Hebei Province Yanshan University

Considering gravity change from ground alignment to space applications, a fuzzy proportional-integral-differential(PID)control strategy is proposed to make the space manipulator track the desired trajectories in different gravity environments. The fuzzy PID controller is developed by combining the fuzzy approach with the PID control method, and the parameters of the PID controller can be adjusted on line based on the ability of the fuzzy controller. Simulations using the dynamic model of the space manipulator have shown the effectiveness of the algorithm in the trajectory tracking problem. Compared with the results of conventional PID control,the control performance of the fuzzy PID is more effective for manipulator trajectory control.

关键词： Space manipulator trajectory tracking ground alignment space applications fuzzy proportional-integral-differential (PID) gravity environment

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MEMS Huygens Clock Based on Synchronized Micromechanical Resonators

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Engineering 2024年第5期36卷 124-131页

作者： Xueyong Wei Mingke Xu Qiqi yang Liu Xu a Yonghong Qi Ziming Ren juan Ren Ronghua huan Zhuangde Jiang State Key Laboratory for Manufacturing System Engineering Xi’an Jiaotong UniversityXi’an 710049China School of Construction Machinery Chang’an UniversityXi’an 710064China Department of Mechanics Zhejiang UniversityHangzhou 310027China

With the continuous miniaturization of electronic devices,microelectromechanical system(MEMS)oscillators that can be combined with integrated circuits have attracted increasing *** study reports a MEMS Huygens clock based on the synchronization principle,comprising two synchronized MEMS oscillators and a frequency compensation *** MEMS Huygens clock improved shorttime stability,improving the Allan deviation by a factor of 3.73 from 19.3 to 5.17 ppb at 1 s.A frequency compensation system based on the MEMS oscillator’s temperature-frequency characteristics was developed to compensate for the frequency shift of the MEMS Huygens clock by controlling the resonator *** effectively improved the long-term stability of the oscillator,with the Allan deviation improving by 1.6343105 times to 30.9 ppt at 6000 *** power consumption for compensating both oscillators simultaneously is only 2.85 mW·℃^(-1).Our comprehensive solution scheme provides a novel and precise engineering solution for achieving high-precision MEMS oscillators and extends synchronization applications in MEMS.

关键词： Frequency stability Huygens clock MEMS Oscillator Synchronization

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