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Benchmark experiment on slab^(238)U with D-T neutrons for validation of evaluated nuclear data

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Nuclear Science and Techniques 2024年第2期35卷 145-159页

作者： Yan-Yan Ding Yang-Bo Nie yue zhang Zhi-Jie Hu Qi Zhao huan-yu zhang Kuo-Zhi Xu Shi-yu zhang Xin-Yi Pan Chang-Lin Lan Jie Ren Xi-Chao Ruan Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Institute of Fluid Physics China Academy of Engineering PhysicsMianyang 62100China

A benchmark experiment on^(238)U slab samples was conducted using a deuterium-tritium neutron source at the China Institute of Atomic *** leakage neutron spectra within energy levels of 0.8-16 MeV at 60°and 120°were measured using the time-of-flight *** samples were prepared as rectangular slabs with a 30 cm square base and thicknesses of 3,6,and 9 *** leakage neutron spectra were also calculated using the MCNP-4C program based on the latest evaluated files of^(238)U evaluated neutron data from CENDL-3.2,ENDF/B-Ⅷ.0,JENDL-5.0,and *** on the comparison,the deficiencies and improvements in^(238)U evaluated nuclear data were *** results showed the following.(1)The calculated results for CENDL-3.2 significantly overestimated the measurements in the energy interval of elastic scattering at 60°and 120°.(2)The calculated results of CENDL-3.2 overestimated the measurements in the energy interval of inelastic scattering at 120°.(3)The calculated results for CENDL-3.2 significantly overestimated the measurements in the 3-8.5 MeV energy interval at 60°and 120°.(4)The calculated results with JENDL-5.0 were generally consistent with the measurement results.

关键词： Leakage neutron spectra Uranium D-T neutron source Evaluated nuclear data

Esophageal Functional Changes in Obstructive Sleep Apnea/Hypopnea Syndrome and Their Impact on Laryngopharyngeal Reflux Disease

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Chinese Medical Journal 2015年第16期128卷 2162-2167页

作者： yue Qu Jing-Ying Ye De-Min Han Li Zheng Xin Cao yu-huan zhang Xiu Ding Department of Otolaryngology Head and Neck Surgery Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Otolaryngology Head and Neck Surgery Beijing Tsinghua Changgung Hospital Tsinghua University Beijing 102218 China Department of Otolaryngology Head and Neck Surgery Beijing Children's Hospital Capital Medical University Beijing 100045 China

Background：Obstructive sleep apnea/hypopnea syndrome （OSAHS） and laryngopharyngeal reflux （LPR） disease have a high comorbidity rate,but the potential causal relation between the two diseases remains *** objectives were to investigate the esophageal functional changes in OSAHS patients and determine whether OSAHS affects LPR by affecting esophageal ***：Thirty-six OSAHS patients and 10 healthy controls underwent 24-h double-probed combined esophageal multichannel intraluminal impedance and pH monitoring simultaneously with ***-resolution impedance manometry was applied to obtain a detailed evaluation of pharyngeal and esophageal ***：There were 13 OSAHS patients （36.1%） without LPR （OSAHS group） and 23 （63.9%） with both OSAHS and LPR （OSAHS and LPR group）.Significant differences were found in the onset velocity of liquid swallows （OVL,P =0.029） and the percent relaxation of the lower esophageal sphincter （LES） during viscous swallows （P =0.049） between the OSAHS and control *** percent relaxation of LES during viscous swallows was found to be negatively correlated with upright distal acid percent time （P =0.016,R =-0.507）,and OVL was found to be negatively correlated with recumbent distal acid percent time （P =0.006,R =-0.557） in the OSAHS and LPR ***：OSAHS patients experience esophageal functional changes,and linear correlations were found between the changed esophageal functional parameters and reflux indicators,which might be the reason that LPR showed a high comorbidity with OSAHS and why the severity of the two diseases is correlated.

关键词： Esophageal Function Laryngopharyngeal Reflux Disease Obstructive Sleep Apnea/Hypopnea Syndrome

Qualitative study on influencing factors of refusal of gastric tube placement in stroke patients with dysphagia

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Nursing Communications 2022年第1期6卷 19-22页

作者： Ao-Yang Li Dong Pang Yang Liu Lu-Si Wang yu-huan zhang the Second Affiliated Hospital of Harbin Medical University Heilongjiang 150086China

Objective:To explore the influencing factors of patients with dysphagia after stroke who refuse to accept gastric tube implantation,and to provide intervention basis for improving the compliance of patients with gastric tube ***:Asemi-structured interview method was used to conduct in-depth interviews with 11 patients who refused gastric tube placement,and the interview data were analyzed by Colaizzi analysis ***:The influencing factors of patients with dysphagia after stroke can be summarized into the following three themes:patient factors(patient's cognition of disease,patient's subjective pain perception and fear),family factors(patient's caregiver's cognition of disease,economic conditions)and medical factors(trust in medical staff,medical education methods).Conclusion:Medical staff should understand the influencing factors of dysphagia after stroke and take positive measures to improve the compliance of patients with gastric tube placement and ensure the treatment effect.

关键词： stroke dysphagia gastric tube insertion treatment decision qualitative research

Delphi and Analytic hierarchy process for the construction of a risk assessment index system for post-stroke shoulder-hand syndrome

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Nursing Communications 2022年第1期6卷 1-6页

作者： yu-huan zhang Chun-Bo Fan Yong-Mei Luo Dong Chen Chun-Xiao Yang Dong Pang Department of Neurology The Second Hospital of Harbin Medical UniversityHeilongjiang150001China Department of Neurology Peking University Third HospitalBeijing100191China

Background:Shoulder-hand syndrome(SHS)is one of the common complications after stroke,which is difficult to cure once it *** risk identification is an effective measure to prevent and treat SHS,but there is no effective tool to assess the risk assessment of ***:To develop a validated tool to assess the risk of SHS occurrence after ***:This was an observational study with a 3-step process:(1)Literature review to establish initial indicators;(2)Application of a modified Delphi method for two rounds of correspondence,with final indicators obtained by modifying each round based on expert opinion;(3)Application of hierarchical analysis to determine the weights of each ***:The initial literature review constructed4 primary indicators and 24 secondary indicators;after the first round of Delphi,a total of 10 secondary indicators were deleted and 6 secondary indicators were added,and the final indicators included 3 primary indicators and 15 secondary indicators,and in the second round,consensus was reached;by AHP analysis,the highest weight was given to existing risk factors(0.5584),followed by relevant medical history(0.3196);lastly,demographic factors(0.1220),and the scores of other secondary indicators met the ***:This study establishes and constructs a post-stroke SHS risk assessment tool,which provides a basis for early identification of SHS and early ***,this study provides a methodological reference for the development of other indicatorssets.

关键词： Analytic hierarchy process Delphi method Stroke patients Shoulder-hand syndrome Shoulder-hand syndrome Risk assessment

新型硅胶管治疗泪小管断裂的临床疗效(英文)

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国际眼科杂志 2019年第1期19卷 9-13页

作者：陈璇杨振田洁张玉环山东省济南市第二人民医院眼科中国250001

目的:评价新型硅胶管(RS一次性使用泪道引流管)治疗泪小管断裂的临床效果。方法:回顾性研究。收集2013-01/2015-10来我院就诊的47例47眼泪小管断裂患者完整的临床资料。在泪小管断裂吻合术中,新型硅胶管从上、下泪小点"U"形置入,在泪道... 详细信息

目的:评价新型硅胶管(RS一次性使用泪道引流管)治疗泪小管断裂的临床效果。方法:回顾性研究。收集2013-01/2015-10来我院就诊的47例47眼泪小管断裂患者完整的临床资料。在泪小管断裂吻合术中,新型硅胶管从上、下泪小点"U"形置入,在泪道中保留3mo。拔管后,观察泪道通畅率、是否伴有泪溢和其他并发症发生情况。结果:所有患者,泪小管吻合成功,新型硅胶管顺利植入。未发生硅胶管相关的并发症,如眼部刺激、泪小点外翻和撕裂、过早脱落等。治愈41例(87%),泪道冲洗通畅,无泪溢。部分治愈4例(9%),患眼轻微泪溢,但泪道冲洗通畅。失败2例(4%),患眼泪溢,泪道冲洗不畅。结论:在泪小管断裂吻合术中,新型硅胶管是一种安全、有效、无创的置入物,其操作过程简单,易于掌握,术者学习曲线短。

关键词：泪小管断裂硅胶管双泪小管置入

Combined Therapy of Psoriasis Vulgaris with UVAB, Thermal Spring Bath and Pulian Ointment: 10-year experience in a single-center

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Combined Therapy of Psoriasis Vulgaris with UVAB, Thermal Sp...

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

全国中青年中西医结合学术（英语）交流会议

作者： Li-Tao zhang, MD, Ph D Dr. Han-Qing zhang yu-huan zhang, MD the department of dermatology, Long March hospital, Tianjin, P. R. China (Dr. Li-Tao zhang and Dr yu-huan zhang, ltzhang@***) and the department of rehabilitation, thermal spring sanatorium of coal mine worker, Shandong Province (Dr. Han-Qing zhang).

Objective: To evaluate the efficacy of UVAB, Pulian ointment and thermal spring in the treatment of psoriasis vulgaris and the safety of its carcinogenesis in long term UVAB exposure of Chinese ***: A retrospective study of treatment of psoriasis vulgaris with UVAB radiation for its efficacy and long-term safety of ***: One psoriasis center of thermal spring sanatorium for colliery worker, Shandong Province. Natural hot spring bath. Metal halide ultraviolet machines. Pulian ***: Almost all patients, both plaque and guttate psoriasis, were from 103 coal mines in central provinces of China. The remainders are from local places of Linyi ***: 586 (70.7%) patients in UVAB/hot spring bath and Pulian ointment (UVAB/HSBP) group fully recovered after 12 weeks’ therapy, 206(24.8%) greatly improved, 32(7.6%) improved, and 5 cases inefficient. In contrast, 272 (64.3%) patients in UVAB/hot spring (UVAB/HSB) group fully cleared after 12 weeks, 102(24.1%) greatly improved, 48(11.3%) improved, and 2 cases inefficient. Patients of both UVAB/HSBP and UVAB/HSB groups were well followed-up and only 820 patients (252 in UVAB/HSB group, 568 in UVAB/HSBP group) were investigated. It was discovered that only in UVAB/HSB group, one patient was suffered with nonmelanoma skin cancer (NMSC), and none NMSC was discovered in UVAB/HSBP ***: UBAB and hot spring bath plus Pulian ointment seems to be an effective and safe method for psoriasis treating with no increasing the risk of NMKC suffering. The low incidence rate of NMKC after UVAB treatment in Chinese might be ethnic and heredity, but the therapeutic advantage in UVAB/HSBP is obvious.

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui yu Yan Xie Jian yu Kun-Ning zhang Zhou-Bo Guo Di Wang Zhao-Xian Li Wei-Qi zhang yu-Ying Tan Li zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer Tianjin First Center HospitalTianjin 300192China Department of Liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

Study on the hydrogen absorption properties of a YGdTbDyHo rare-earth high-entropy alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 127-135页

作者： Tongyue Li Ziliang Xie Wenjiao Zhou huan Tong Dawen Yang Anjia zhang yuan Wu Xiping Song State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China Whole Win(Beijing)Materials Sci.&Tech.Co. Ltd.Beijing 100083China

This study investigated the microstructure and hydrogen absorption properties of a rare-earth high-entropy alloy(HEA),*** indicated that the YGdTbDyHo alloy had a microstructure of equiaxed grains,with the alloy elements distributed *** hydrogen absorption,the phase structure of the HEA changed from a solid solution with an hexagonal-close-packed(HCP)structure to a high-entropy hydride with an faced-centered-cubic(FCC)structure without any secondary phase *** alloy demonstrated a maximum hydrogen storage capacity of 2.33 H/M(hydrogen atom/metal atom)at 723 K,with an enthalpy change(ΔH)of-141.09 kJ·mol^(-1)and an entropy change(ΔS)of-119.14 J·mol^(-1)·K^(-1).The kinetic mechanism of hydrogen absorption was hydride nucleation and growth,with an apparent activation energy(E_(a))of 20.90 kJ·mol^(-1).Without any activation,the YGdTbDyHo alloy could absorb hydrogen quickly(180 s at 923 K)with nearly no incubation period *** reason for the obtained value of 2.33 H/M was that the hydrogen atoms occupied both tetrahedral and octahedral *** results demonstrate the potential application of HEAs as a high-capacity hydrogen storage material with a large H/M ratio,which can be used in the deuterium storage field.

关键词： rare-earth high-entropy alloy hydrogen absorption capacity pressure–composition–temperature curves kinetics

Global research status and trends of somatic symptom disorder: A bibliometric study

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World Journal of Psychiatry 2025年第1期15卷 168-178页

作者： Chao Yang Kun zhang Qian Wang Shuai Wang huan Li Kai zhang Department of Psychiatry Beijing Luhe HospitalCapital Medical UniversityBeijing 100001China Department of Psychiatry Chaohu Hospital of Anhui Medical UniversityHefei 238000Anhui ProvinceChina School of Medicine Jiangxi University of TechnologyNanchang 510001Jiangxi ProvinceChina School of Public Health Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

BACKGROUND With the growing scholarly and clinical fascination with somatic symptom dis-order(SSD),a bibliometric analysis is *** To conduct a bibliometric analysis to investigate the current status and frontiers of *** The documents related to SSD are obtained from the web of science core collection database(WoSCC),and VOSviewer 1.6.16 from January 1,2000 to December 31,2023,and the WoSCC’s literature analysis wire were used to conduct the biblio-metric *** A total of 567 documents related to SSD were included,and 2325 authors across 947 institutions from 57 countries/regions have contributed to SSD research,published in 277 *** most productive author,institution,country and journal were Löwe B,University of Hamburg,Germany,and Journal of Psycho-somatic Research *** first high-cited document was published in the Journal of Psychosomatic Research in 2013 by Dimsdale JE and colleagues,which explored the rationale behind the SSD diagnosis introduction in diagnostic and statistical manual of mental *** In conclusion,the main research hotspots and frontiers in the field of SSD are validity and reliability of the SSD criteria,functional impairment of SSD,and the treatment for *** high-quality studies are needed to assess the diagnosis and treatment of SSD.

关键词： Somatic symptom disorder Validity and reliability Functional impairment Treatment Bibliometric analysis