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The Chinese-German Journal of Clinical Oncology 2008年第4期7卷 200-202页

作者： Jun Guo Weiping Li Degang Song Zhehai Wang Jie Liu Changzheng Li Zhen Chen huan shi Department of Oncological Third Internal Medicine Shandong Tumor Hospital Jinan 250117 China New York Downtown hospital New York NY 10038 USA

Objective： To evaluate the efficacy and toxicity of docetaxel and vinorelbine as second-line chemotherapy in the treatment of advanced non-small cell lung cancer （NSCLC）. Methods： 48 histologically or cytologically confirmed NSCLC patients with progressive or recurrent disease after first-line treatment were treated with docetaxel and vinoretbine. The chemotherapy included vinorelbine （25 mg/m^2） on days 1,5 and docetaxel （60 mg/m^2） on day 1. The treatment was repeated every 3 weeks. Patients receiving at least two cycles were evaluated for efficacy and toxicity. Results： Of 48 patients, 1 patient achieved complete response and 16 achieved partial response. Overall response rate for all 48 patients was 35.4% （17/48）. Main hematologic toxicities included neutropenia （60.4%） and febrile neutropenia （29.2%） and non-hematologic toxicities were mild. Conclusion： The combination of docetaxel-vinorelbine as second-line chemotherapy is an effective regimen with manageable toxicity for the treatment of advanced NSCLC. Further studies may confirm these results.

关键词： non-small cell lung cancer (NSCLC) second-line chemotherapy docetaxel vinorelbine efficacy

Kindergartens Reopening in the Period of Regular Epidemic Prevention and Control, Benefitial or Harmful?

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Current Medical Science 2020年第5期40卷 817-821页

作者： Qiao-qiao DONG Li-ru QIU Li-ming CHENG Sai-nan SHU Yu CHEN Yue ZHAO Yan HAO huan shi Xiao-ping LUO Department of Pediatrics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Laboratory Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

In the period of regular epidemic prevention and control of coronavirus disease 2019(COVID-19)in our country,work resumption has been fully *** there are still new sporadic local cases and imported cases across the *** this situation,whether kindergartens reopening will increase the risk of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)spread still remains *** reviewed two pediatric patients with moderate COVID-19,collected the epidemiologic information and monitored the cycle threshold value of rectal specimen and the viral loads,and discussed the transmission of SARS-CoV-2 in pediatric patients and the virulence of feces in children with moderate COVID-19,in order to analyze the risk of kindergartens reopening.

关键词： COVID-19 SARS-CoV-2 transmission children viral load

CD4^＋CD25^＋ regulatory T lymphocytes in tuberculous pleural effusion

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Chinese Medical Journal 2008年第7期 581-586页

作者： QIN Xue-jun shi huan-zhong LIANG Qiu-li huanG Lu-ying YANG Hai-bo Institute of Respiratory Diseases First Affiliated HospitalGuangxi Medical University Nanning Guangxi 530021 China

Background Active suppression by CD4^＋CD25^＋ regulatory T lymphocytes plays an important role in the down-regulation of T cell responses to foreign and self-antigens. This study was conducted to analyze whether the CD4^＋CD25^＋ regulatory T cells exist and function normally in tuberculous pleural effusion. Methods The percentages of CD4^＋CD25^＋ T cells in pleural effusion and peripheral blood from patients with tuberculous pleurisy and peripheral blood from healthy control subjects were determined by flow cytometry. The expression of forkhead transcription factor Foxp3 was also examined. CD4^＋CD25^＋ and CD4^＋CD25^-T cells from pleural effusion and blood were isolated, and were cultured to observe the effects of CD4^＋CD25^＋ T cells on proliferation response of CD4^＋CD25^- T cells in vitro. Results There were increased numbers of CD4^＋CD25^＋ T cells in tuberculous pleural effusion compared with peripheral blood from both patients with tuberculous pleurisy and normal subjects, and these cells demonstrated a constitutive high-level expression of Foxp3. Moreover, CD4^＋CD25^＋ T cells mediated potent inhibition of proliferation response of CD4^＋CD25^- T cells. Conclusion The increased CD4^＋CD25^＋ T cells in tuberculous pleural effusion express a high level of Foxp3 transcription factor, while potently suppressing the proliferation of CD4^＋CD25^- T cells.

关键词： CD4^+CD25^+ T cells pleural effusion regulatory T cells tuberculosis

Insight into role of Ni/Fe existing forms in reversible oxygen catalysis based on Ni-Fe single-atom/nanoparticles and N-doped carbon

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Rare Metals 2022年第12期41卷 4034-4040页

作者： Hong-Yu Gong Xiu Liang Guan-Liang Sun Dong-Wei Li Xiang-Jun Zheng huan shi Kai Zeng Guan-Chen Xu Yong Li Rui-Zhi Yang Chang-Zhou Yuan Advanced Materials Institute Qilu University of Technology(Shandong Academy of Sciences)Jinan 250014China Shandong Saikesaisi Hydrogen Energy Co. LtdJinan 250100China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Materials Science&Engineering University of JinanJinan 250014China College of Energy Soochow Institute for Energy and Materials InnovationsSoochow UniversitySuzhou 215006China

Oxygen catalysis reactions play essential roles in metal-air batteries,fuel cells,water electrolysis and artificial photosynthesis,with their development receiving significant attention in recent *** the structure-activity relationship plays an important role in the construction and performance optimization of reversible oxygen catalyst.

关键词： catalyst catalysis reversible

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广西大明山人文历史朔源

贵州民族研究 2007年第5期27卷 103-109页

作者：黄世杰广西民族大学广西南宁530006

广西的大明山历史上其名称曾经有过多次的变迁:壮语名字叫"Byacwx",为祖山、灵山的意思。汉文文献记载的大明山,古称A天之山、博邪山、镆钅耶山、五峰山、大鸣山、大名山、大冥山等。历史归属和称呼的多次变迁并无损于大明山文明的发展... 详细信息

广西的大明山历史上其名称曾经有过多次的变迁:壮语名字叫"Byacwx",为祖山、灵山的意思。汉文文献记载的大明山,古称A天之山、博邪山、镆钅耶山、五峰山、大鸣山、大名山、大冥山等。历史归属和称呼的多次变迁并无损于大明山文明的发展,反而给予了大明山本身蕴含有某种历史魅力,无疑也增加了这座大山对世人的诱惑。

关键词：大明山人文历史汜天之山博邪山镆鎁山

Treatment of phenol wastewater by microwave-induced CIO_2-CuO_x/Al_2O_3 catalytic oxidation process

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Journal of Environmental Sciences 2007年第12期19卷 1510-1515页

作者： BI Xiao-yi WANG Peng JIANG Hong XU huan-yan shi Shu-jie huanG Jun-li Research Center for Green Chemistry and Technology School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China

The catalyst of CUOx/Al2O3 was prepared by the dipping-sedimentation method using y-Al2O3 as a supporter. CuO and Cu2O were loaded on the surface of Al2O3, characterized by X-ray diffraction （XRD） and X-ray photoelectron spectroscopy （XPS）. In the presence of CuOx/Al2O3, the microwave-induced chlorine dioxide （ClO2） catalytic oxidation process was conducted for the treatment of synthetic wastewater containing 100 mg/L phenol. The factors influencing phenol removal were investigated and the results showed that microwave-induced C102-CuOx/ml203 process could effectively degrade contaminants in a short reaction time with a low oxidant dosage, extensive pH range. Under a given condition （ClO2 concentration 80 mg/L, microwave power 50 W, contact time 5 latin, catalyst dosage 50 g/L, pH 9）, phenol removal percentage approached 92.24%, corresponding to 79.13% of CODcr removal. The removal of phenol by microwave-induced ClO2-CuOx/Al2O3 catalytic oxidation process was a complicated non-homogeneous solid/water reaction, which fitted pseudo-first-order by kinetics. Compared with traditional ClO2 oxidation, ClO2 catalytic oxidation and microwave-induced ClO2 oxidation, microwave-induced ClO2 catalytic oxidation system could significantly enhance the degradation efficiency. It provides an effective technology for the removal of phenol wastewater.

关键词： microwave-induced oxidation ClO2 CuOx/Al2O3 phenol wastewater

Extensions and Refinements of Adamovic's Inequality

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Chinese Quarterly Journal of Mathematics 2004年第1期19卷 35-40页

作者： shihuan-nan LIDa-mao Teacher＇sCollege BeijingUnionUniversityBeijing100011China Teacher＇sCollege BeijingUnionUniversityBeijing100011China

In this article, by means of the theory of majorization, Adamovic's inequality is extended to the cases of the general elementary symmetric functions and its duals, and the refined and reversed forms are also given. A... 详细信息

关键词： Adamovic's inequality elementary symmetric function majorization simplex

Dissolved organic matter accelerates microbial degradation of 17 alpha-ethinylestradiol in the presence of iron mineral

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Journal of Environmental Sciences 2024年第5期139卷 364-376页

作者： huan He Min shi Xiaoxia Yang Juhong Zhan Yanting Lin Ziwei Guo Zhicheng Liao Chaochao Lai Xiaomin Ren Bin huang Xuejun Pan Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming 650500China Yunnan Provincial Key Lab of Soil Carbon Sequestration and Pollution Control Kunming 650500China Research Institute for Environmental Innovation(Suzhou)Tsinghua Suzhou 215163China

Dissolved organic matter(DOM)and iron minerals widely existing in the natural aquatic environment can mediate the migration and transformation of organic ***,the mechanism of interaction between DOM and iron minerals in the microbial degradation of pollutants deserves further *** this study,the mechanism of 17 alphaethinylestradiol(EE2)biodegradation mediated by humic acid(HA)and three kinds of iron minerals(goethite,magnetite,and pyrite)was *** results found that HA and iron minerals significantly accelerated the biodegradation process of EE2,and the highest degradation efficiency of EE2(48%)was observed in the HA-mediated microbial system with pyrite under aerobic ***,it had been demonstrated that hydroxyl radicals(HO·)was the main active substance responsible for the microbial degradation of ***·is primarily generated through the reaction between hydrogen peroxide secreted by microorganisms and Fe(II),with aerobic conditions being more *** presence of iron minerals and HA could change the microbial communities in the EE2 biodegradation *** findings provide new information for exploring the migration and transformation of pollutants by microorganisms in iron-rich environments.

关键词： Dissolved organic matter Iron mineral 17 alpha-ethinylestradiol Biodegradation

基于最小二乘法的Lagrange方法在衰减冲击波中的研究

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高压物理学报 2014年第2期28卷 215-220页

作者：陶为俊浣石广州大学工程抗震研究中心广东广州510405

在已知粒子速度的情况下,采用现有Lagrange分析方法求解动力学方程仍有不足。针对这一情况,将反解法和自洽检验法相结合,提出了基于最小二乘法的Lagrange反解法。该方法的理论精度能够实现应力沿路径线的M(M为迹线数)阶导数恒为零,并且... 详细信息

在已知粒子速度的情况下,采用现有Lagrange分析方法求解动力学方程仍有不足。针对这一情况,将反解法和自洽检验法相结合,提出了基于最小二乘法的Lagrange反解法。该方法的理论精度能够实现应力沿路径线的M(M为迹线数)阶导数恒为零,并且能够满足自洽检验法。通过对一组混凝土的实验数据进行处理,并将处理结果与实验结果以及传统Lagrange反解法进行对比,比较结果表明,该方法不仅使得迹线函数能够很好地反应各物理量沿迹线的变化性态,而且还能够适当减小偶然误差。

关键词： Lagrange分析本构关系最小二乘法混凝土