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Influencing mechanism of high solid concentration on anaerobic mono-digestion of sewage sludge without agitation

Frontiers of Environmental Science & Engineering 2015年第6期9卷 1108-1116页

作者： Yuyao ZHANG huan li Can liU Yingchao CHENG Key Laboratory of Microorganism Application and Risk Control of Shenzhen Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China

High-solids anaerobic digestion of sewage sludge was a promising process, but high solid concentra- tion negatively influenced methane production. The influencing mechanism was systematically analyzed in this study through a series of static anaerobic digestion experiments at total solids （TS） contents of 3%--15%. The results showed that TS 6% was the boundary between low- solids and high-solids anaerobic digestion, and the accumulative methane yield decreased exponentially when TS increased from 6% to 15%. The performance of anaerobic digestion was directly determined by the efficiency of mass transfer, and the relation between methane yield and sludge diffusive coefficients was well described by a power function. Thus, the increasing TS resulted in an exponential increase in sludge viscosity but an exponential decrease in diffusive coefficient. The blocked mass transfer led to the accumulation of volatile fatty acids （VFAs） and free ammonia. Acetic metabolism was the main process, whereas butyric and propionic metabolisms occurred at the initial stage of high-solids anaerobic digestion. The concentration of VFAs reached the maximum at the initial stage, which were still lower than the threshold influencing methanogens. The concen- tration of free ammonia increased gradually, and the methanogenesis was inhibited when free ammonia nitro- gen exceeded 50 mg.L^-1. Consequently, the deterioration of high-solids anaerobic digestion was related to the blocked mass transfer and the resulting ammonia accumu- lation.

关键词： anaerobic digestion methane sewage sludge,volatile fatty acids free ammonia

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Thermo-elasto-visco-plastic finite element analysis on formation and propagation of off-corner subsurface cracks in bloom continuous casting

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Journal of Iron and Steel Research(International) 2017年第11期24卷 1159-1168页

作者： Yu-jun li huan li Peng Lan Hai-yan Tang Jia-quan Zhang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The formation and propagation of the popular off-corner subsurface cracks in bloom continuous casting were investigated through thermo-mechanical analysis using three coupled thermo-mechanical models. A two-dimensional thermo-elasto-visco-plastic finite element model was developed to predict the mould gap evolution, temperature profiles and deformation behavior of the solidified shell in the mould region. Then, a three-dimensional model was adopted to calculate the shell growth, tempera- ture history and the development of stresses and strains of the shell in the following secondary cooling zones. Finally, another three-dimensional model was used to analyze the stress distributions in the straightening region, The results showed that the off-corner cracks in the shell originated from the mould owing to the tensile strain developed in the crack sensitive regions of the solidification front, and they could be driven deeper by the possible severe surface temperature rebound and the extensive tensile stress in the secondary cooling zone, especially upon the straightening operation of the bloom casting. It is revealed that more homogenous shell temperature and thickness can be obtained through optimization of mould corner radius, casting speed and secondary cooling scheme, which help to decrease stress and strain concentration and therefore prevent the initiation of the cracks.

关键词： Thermo elasto-visco-plastic finite element model Off-corner subsurface crack Mould corner radius Temperature rebound Straightening operation Bloom continuous casting

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Clear cell sarcoma of soft tissue in pleural cavity: A case report

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World Journal of Clinical Cases 2019年第19期7卷 3126-3131页

作者： Yang-Tian Chen Zhi Yang huan li Chen-Hui Ni Department of Thoracic Surgery The Affiliated People Hospital of Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina Department of Pathology The Affiliated People Hospital of Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina

BACKGROUND Clear cell sarcoma(CCS)of soft tissue is a rare malignant soft tissue sarcoma usually reported to locate at distal end of extremities and rarely at trunk.Herein,we report a case of CCS in pleural cavity.CASE SUMMARY A 31-year-old male was admitted for an uncertain mass in left pleural cavity in routine physical examination without any symptoms.A VATS surgery was performed to remove the tumor.The pathological finding displayed a cystic mass with 6.5 cm at the longest diameter,dark red in section and cysts could be found locally.A strong expression of S-100,HMB45 and Vimentin was detected in immunohistochemical staining,which was inclined to the diagnosis of the CCS of soft tissue.The patient refused chemotherapy,radiotherapy and targeted therapy because of the personal financial situation.Follow-up computed tomography scans were done at the 90th postoperative day and the 180th postoperative day,and no obvious sign of recurrence was found till now.CONCLUSION CCS of soft tissue also can be found in pleural cavity although in an extremely rare incidence.Radical resection is useful to improve the prognosis.

关键词： Sarcoma Clear cell sarcoma Clear cell sarcoma of soft tissue Treatment Case report

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The Ontology of Biological and Clinical Statistics （OBCS）-based statistical method standardization and meta-analysis of host responses to yellow fever vaccines

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Frontiers of Electrical and Electronic Engineering in China 2017年第4期5卷 291-301页

作者： Jie Zheng huan li Qingzhi liu Yongqun He Department of Genetics University of Pennsylvania Perelman School of Medicine Philadelphia PA 19104 USA Health Science Center Shenzhen'University.Shenzhen 518000 China Department of Mathematics University of Maryland College Park MD 20742 USA Unit for Laboratory Animal Medicine University of Michigan Medical School Ann Arbor MI 48109 USA Department of Microbiology and Immunology University-of Michigan Medical School Ann Arbor MI 48109 USA Center for Computational Medicine and Bioinformatics University of Michigan Medical School Ann Arbor MI 48109 USA Comprehensive Cancer Center University of Michigan Medical School Ann Arbor MI 48109 USA

Background： The community-based Ontology of Biological and Clinical Statistics （OBCS） represents and standardizes biological and clinical data and statistical methods. Methods： Both OBCS and the Vaccine Ontology （VO） were used to ontologically model various components and relations in a typical host response to vaccination study. Such a model was then applied to represent and compare three microarray studies of host responses to the yellow fever vaccine YF-17D. A literature meta-analysis was then conducted to survey yellow fever vaccine response papers and summarize statistical methods, using OBCS. Results： A general ontological model was developed to identify major components in a typical host response to vaccination. Our ontology modeling of three similar studies identified common and different components which may contribute to varying conclusions. Although these three studies all used the same vaccine, human blood samples, similar sample collection time post vaccination, and microarray assays, statistically differentially expressed genes and associated gene functions differed, likely due to the differences in specific variables （e.g., microarray type and human variations）. Our manual annotation of 95 papers in human responses to yellow fever vaccines identified 38 data analysis methods. These statistical methods were consistently represented and classified with OBCS. Eight statistical methods not available in existing ontologies were added to OBCS. Conclusions： The study represents the first single use case of applying OBCS ontology to standardize, integrate, and use biomedical data and statistical methods. Our ontology-based meta-analysis showed that different experimental results might be due to different experimental assays and conditions, sample variations, and data analysis methods.

关键词： OBCS ontology vaccine host response to vaccination statistical data analysis

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基于区块链的工业互联网数据溯源技术实现

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自动化与仪器仪表 2024年第1期 89-92,98页

作者：李焕咸阳职业技术学院陕西咸阳712000

针对工业互联网数据量大、数据关系复杂的问题,提出一种基于区块链和PROV-DM模型的数据溯源方法,该方法采用PROV-DM模型进行溯源信息记录,可描述多种工业互联网数据关系;储存结构为区块链-区块链,可减少溯源查询过程的数据计算量,提高... 详细信息

针对工业互联网数据量大、数据关系复杂的问题,提出一种基于区块链和PROV-DM模型的数据溯源方法,该方法采用PROV-DM模型进行溯源信息记录,可描述多种工业互联网数据关系;储存结构为区块链-区块链,可减少溯源查询过程的数据计算量,提高溯源查询效率;在每个区块链都设置有智能合约,可有效保证加密解密速率。经试验,该数据溯源方法可完成数据溯源记录和溯源查询等多项功能、对数据量较大的溯源信息加密解密速率高、溯源查询效率高、吞吐量大,基本满足工业互联网数据溯源需求。因此,基于区块链和PROV-DM模型的数据溯源方法在工业互联网的实际应用中具有一定的价值。

关键词：区块链数据溯源 PROV-DM模型

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煤矿通风安全管理及瓦斯防治技术探究

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能源与节能 2024年第4期 198-201页

作者：李欢山西潞安化工集团通风部山西长治046204

煤炭行业是中国矿业的重要组成部分,也是一个安全风险极高的行业。通风和瓦斯防治技术作为煤矿安全管理的两个关键技术,对于煤矿的安全生产具有重要意义。首先,在论述煤矿通风安全管理及瓦斯防治重要性的基础上,分析了通风不良和瓦斯超... 详细信息

煤炭行业是中国矿业的重要组成部分,也是一个安全风险极高的行业。通风和瓦斯防治技术作为煤矿安全管理的两个关键技术,对于煤矿的安全生产具有重要意义。首先,在论述煤矿通风安全管理及瓦斯防治重要性的基础上,分析了通风不良和瓦斯超标这2个问题,为接下来的探究指明了方向。接着,深入分析了煤矿通风安全管理以及瓦斯防治技术。最后,指出了煤矿通风安全管理及瓦斯防治技术的发展方向,以期对煤矿安全管理有一定的帮助。

关键词：煤矿通风安全管理瓦斯防治

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A genetic variant in IL-6 lowering its expression is protective for critical patients with COVID-19

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Signal Transduction and Targeted Therapy 2022年第5期7卷 1627-1633页

作者： Bo Gong Lulin huang Yongquan He Wen Xie Yi Yin Yi Shi Jialing Xiao ling Zhong Yi Zhang Zhilin Jiang Fang Hao Yu Zhou huan li li Jiang Xingxiang Yang Xiangrong Song Yan Kang lin Tuo Yi huang Ping Shuai Yuping liu Fang Zheng Zhenglin Yang Department of Health Management Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuanChina Sichuan Provincial Key Laboratory for Human Disease Gene Study Center for Medical GeneticsDepartment of laboratory medicineSichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuanChina Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences(2019RU026) Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuanChina Institute of Chengdu Biology Sichuan Translational Medicine HospitalChinese Academy of SciencesChengduSichuanChina Center for Gene Diagnosis&Department of Laboratory Medicine Zhongnan Hospital of Wuhan UniversityWuhanChina Department of Laboratory Medicine Wuhan Leishenshan HospitalWuhanHubeiChina Infectious Disease Department Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610041China Department of Critical Care Medicine Frontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengduChina

Critical coronavirus disease 2019(COVID-19)is associated with high mortality and potential genetic factors have been reported to be involved in the development of critical COVID-19.We performed a genome-wide association study to identify the genetic factors responsible for developing critical COVID-19.632 critical patients with COVID-19 and 3021 healthy controls from the Chinese population were recruited.First,we identified a genome-wide significant difference of IL-6 rs2069837(p=9.73×10^(−15),OR=0.41)between 437 critical patients with COVID-19 and 2551 normal controls in the discovery cohort.

关键词： protective patients mortality

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农机深翻整地作业及高标准农田建设分析

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中国农机装备 2024年第3期 89-91页

作者：李焕山东省郓城县农业农村局菏泽274700

随着乡村振兴战略的实施和农业现代化的推进,农机深翻整地技术在高标准农田的建设中得到了广泛应用。深翻联合整地技术通过深层翻转土壤并结合多功能作业,如松土、施肥、耙整和起垄,有效改善了土壤的物理和化学特性,为作物生长创造了更... 详细信息

随着乡村振兴战略的实施和农业现代化的推进,农机深翻整地技术在高标准农田的建设中得到了广泛应用。深翻联合整地技术通过深层翻转土壤并结合多功能作业,如松土、施肥、耙整和起垄,有效改善了土壤的物理和化学特性,为作物生长创造了更优良的生长环境。在阐述农机深翻整地概念及其在现代农业生产中的应用基础上,探讨了其在高标准农田建设中的关键作用和实施策略,分析了通过多部门合作和技术整合以实现农业生产高效与可持续发展的途径。

关键词：农机深翻整地高标准农田建设策略

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基于“红医精神”的医学影像实训教学思政体系建设研究

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科教文汇 2024年第3期 87-90页

作者：李欢陕西能源职业技术学院陕西咸阳712000

医学影像实训教学是培养医学专业学生实践能力和思想道德素质的重要环节。在当前社会,构建基于“红医精神”的医学影像实训教学思政体系不仅是培养医学专业人才的需要,还是推动我国医学事业蓬勃发展的重要举措。该文以弘扬“红医精神”... 详细信息

医学影像实训教学是培养医学专业学生实践能力和思想道德素质的重要环节。在当前社会,构建基于“红医精神”的医学影像实训教学思政体系不仅是培养医学专业人才的需要,还是推动我国医学事业蓬勃发展的重要举措。该文以弘扬“红医精神”的理念为核心,在教学内容、教学方法等方面进行设计,通过实验室实习和实地观摩、社会实践和志愿服务等形式,为学生提供实践锻炼的机会,并引导学生通过实践体验和思考,增强其对“红医精神”的理解和认同。同时,加强师资队伍培养和教师思政教育能力的提升。最后,建立思政教育平台,为医学影像实训教学提供良好的思想引导和教育资源。以上措施的实施,可以培养出深度理解和践行“红医精神”的医学专业人才,为人民群众的健康服务做出积极贡献。

关键词：红医精神医学影像实训教学思政体系建设路径

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基于能量流向的变压器饼式绕组散热分析及试验研究

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中国电机工程学报 2024年第8期44卷 3327-3336,I0033页

作者：李欢刘云鹏毕瀚文李东阳黎晏霖范晓舟河北省输变电设备安全防御重点实验室(华北电力大学) 河北省保定市071003

变压器热点温度作为运行经济性、安全性的关键指标,是设备在线监测及状态评估中的重点。该文对变压器内部散热进行研究,着眼于饼式绕组及其油道结构,基于能量流向建立绕组温度变化的物理模型。基于这一模型,在一台内置分布式传感光纤的1... 详细信息

变压器热点温度作为运行经济性、安全性的关键指标,是设备在线监测及状态评估中的重点。该文对变压器内部散热进行研究,着眼于饼式绕组及其油道结构,基于能量流向建立绕组温度变化的物理模型。基于这一模型,在一台内置分布式传感光纤的110kV三相ONAN变压器上开展试验研究,使用分布式光纤测温(distributed temperature sensing,DTS)技术对运行状况下的绕组整体温度分布进行实时监测,分析绕组在ONAN冷却方式下的散热状况。在变压器启动初期,绕组各处散热量较低,温升速率较快。约2 h后,各饼散热量基本与损耗相一致,散热率可达98%以上,因此将这一阶段称为准稳态。准稳态阶段,绕组整体散热率基本一致。负载变化前期不同位置散热量的差异是温度梯度形成的主要原因。基于DTS手段及散热器进出口处油温,提出绕组每饼平均对流换热系数的计算方法,基于无量纲数建立绕组内外表面局部对流换热系数的计算方法,对不同位置、负载率下两种对流换热系数的变化规律进行分析获得了绕组运行过程中对流换热系数分布规律及变化趋势。

关键词：变压器饼式绕组散热分析对流换热系数分布式光纤传感

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