检索结果-南通市图书馆

Prevalence and Risk Factors for Chronic Obstructive Pulmonary Disease Among Adults Aged 50 and Above-10 CKB Study Areas,China,2020–2021

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2024年第43期6卷 1126-1131页

作者： Wei Yu Yongbing Lan Dianjianyi Sun Pei Pei Ling Yang Yiping Chen huaidong du Yingcai Yang Dan Schmidt Junshi Chen Zhengming Chen Jun Lyu Liming Li Canqing Yu Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityBeijingChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUnited Kingdom Shinan District Center for Disease Control and Prevention Qingdao CityShandong ProvinceChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina.

What is already known about this topic?The prevalence of COPD in Chinese individuals aged 50 years and above was obviously higher than that in younger adults,but the risk factors for this age group were *** is added by this report?The prevalence was estimated at 12.8%and 5.7%for males and females over 50 in 2020–2021,with confirmed risk factors of cigarette smoking,a family history of respiratory diseases,respiratory symptoms,and a history of cough or respiratory diseases during *** are the implications for public health practice?The findings may help clinicians and the public identify individuals at high risk of COPD and take targeted measures in a timely manner.

关键词： respiratory diseases prevalence

Association of physical activity with risk of chronic kidney disease in China:A population-based cohort study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第2期13卷 204-211页

作者： Kexiang Shi Yunqing Zhu Jun Lv Dianjianyi Sun Pei Pei huaidong du Yiping Chen Ling Yang Bing Han Rebecca Stevens Junshi Chen Zhengming Chen Liming Li Canqing Yu China Kadoorie Biobank collaborative group Department of Epidemiology&Biostatistics School of Public HealthPeking University Health Science CenterBeijing 100191China Peking University Center for Public Health and Epidemic Preparedness&Response Beijing 100191China Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijing 100191China Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxford OX37LFUK Medical Research Council Population Health Research Unit at the University of Oxford Oxford OX37LFUK NCDs Prevention and Control Department Henan Center for Disease Control and PreventionZhengzhou 450016China China National Center for Food Safety Risk Assessment Beijing 100022China 不详

Background:Information on the association between physical activity(PA)and the risk of chronic kidney disease(CKD)is *** aimed to explore the associations of total,domain-specific,and intensity-specific PA with CKD and its subtypes in ***:The study included 475,376 adults from the China Kadoorie Biobank aged 30-79 years during 2004-2008 at *** interviewer-administered questionnaire was used to collect the information about PA,which was quantified as metabolic equivalent of task hours per day(MET-h/day)and categorized into 4 groups based on *** regression was used to analyze the association between PA and CKD ***:during a median follow-up of 12.1 years,5415 incident CKD cases were documented,including 1159 incident diabetic kidney disease(DKD)cases and 362 incident hypertensive nephropathy(HTN)*** PA was inversely associated with CKD risk,with an adjusted hazard ratio(HR,95%confidence interval(95%CI))of 0.83(0.75-0.92)for incident CKD in the highest quartile of total PA as compared with participants in the lowest *** results were observed for risk of DKD and HTN,and the corresponding HRs(95%CIs)were 0.75(0.58-0.97)for DKD risk and 0.56(0.37-0.85)for HTN *** nonoccupational PA,low-intensity PA,and moderate-to-vigorous-intensity PA were significantly associated with a decreased risk of CKD,with HRs(95%CIs)of 0.80(0.73-0.88),0.85(0.77-0.94),and 0.85(0.76-0.95)in the highest quartile,***:PA,including nonoccupational PA,low-intensity PA,and moderate-to-vigorous-intensity PA,was inversely associated with the risk of CKD,including DKD,HTN,and other CKD,and such associations were dose dependent.

关键词： Chronic kidney disease Domain Intensity Physical activity

Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese

在线全文

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第4期9卷 399-406,I0044-I0065页

作者： Songchun Yang Zhijia Sun Dong Sun Canqing Yu Yu Guo Dianjianyi Sun Yuanjie Pang Pei Pei Ling Yang Iona Y Millwood Robin G Walters Yiping Chen huaidong du Yan Lu Sushila Burgess Daniel Avery Robert Clarke Junshi Chen Zhengming Chen Liming Li Jun Lv On behalf of the China Kadoorie Biobank Collaborative Group Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunanChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Fuwai Hospital Chinese Academy of Medical Sciences BeijingChina Medical Research Council Population Health Research Unit at the University of Oxford OxfordUK Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK NCDs Prevention and Control Department Suzhou CDCSuzhouJiangsuChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina 不详

Background and purpose Previous studies,mostly focusing on the European population,have reported polygenic risk scores(PRSs)might achieve risk stratification of *** aimed to examine the association strengths of PRSs with risks of stroke and its subtypes in the Chinese *** Participants with genome-wide genotypic data in China Kadoorie Biobank were split into a potential training set(n=22191)and a population-based testing set(n=72150).Four previously developed PRSs were included,and new PRSs for stroke and its subtypes were *** PRSs showing the strongest association with risks of stroke or its subtypes in the training set were further evaluated in the testing *** proportional hazards regression models were used to estimate the association strengths of different PRSs with risks of stroke and its subtypes(ischaemic stroke(IS),intracerebral haemorrhage(ICH)and subarachnoid haemorrhage(SAH)).Results In the testing set,during 872919 person-years of follow-up,8514 incident stroke events were *** PRSs of any stroke(AS)and IS were both positively associated with risks of AS,IS and ICH(p<0.05).The HR for per SD increment(HR_(SD))of PRSAS was 1.10(95%CI 1.07 to 1.12),1.10(95%CI 1.07 to 1.12)and 1.13(95%CI 1.07 to 1.20)for AS,IS and ICH,*** corresponding HR_(SD) of PRS_(IS) was 1.08(95%CI 1.06 to 1.11),1.08(95%CI 1.06 to 1.11)and 1.09(95%CI 1.03 to 1.15).PRS_(ICH) was positively associated with the risk of ICH(HR_(SD)=1.07,95%CI 1.01 to 1.14).PRSS_(AH) was not associated with risks of stroke and its *** addition of current PRSs offered little to no improvement in stroke risk prediction and risk *** In this Chinese population,the association strengths of current PRSs with risks of stroke and its subtypes were moderate,suggesting a limited value for improving risk prediction over traditional risk factors in the context of current genome-wide association study under-representing the East Asia

关键词： testing prediction increment

Associations of muscle mass,strength,and quality with all-cause mortality in China:a population-based cohort study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2022年第11期135卷 1358-1368页

作者： Man Wu Yuxia Wei Jun Lv Yu Guo Pei Pei Jiachen Li huaidong du Ling Yang Yiping Chen Xiaohui Sun Hua Zhang Junshi Chen Zhengming Chen Canqing Yu Liming Li 无 Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Key Laboratory of Molecular Cardiovascular Sciences Ministry of EducationPeking UniversityBeijing 100191China Peking University Center for Public Health and Epidemic Preparedness&Responses Beijing 100191China National Coordinating Center of China Kadoorie Biobank Chinese Academy of Medical SciencesBeijing 102308China Medical Research Council Population Health Research Unit the University of OxfordOxford OX37LFUK Clinical Trial Service Unit and Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxford OX37LFUK NCDs Prevention and Control Department Qingdao CDCQingdaoShandong 266033China NHC Key Laboratory of Food Safety Risk Assessment China National Center for Food Safety Risk AssessmentBeijing 100022China. on behalf of the China Kadoorie Biobank Collaborative Group

Background It remains unclear about the association of muscle mass,strength,and quality with death in the general Chinese population of diverse economical and geographical *** present study aimed to comprehensively examine such associations across different regions in *** Based on the China Kadoorie Biobank study,the present study included 23,290 participants who were aged 38 to 88 years and had no prevalent cardiovascular diseases or *** mass and grip strength were measured using calibrated *** muscle quality was defined as the ratio of grip strength to arm muscle *** muscle mass,grip strength,and arm muscle quality were defined as the sex-specific lowest quintiles of muscle mass index,grip strength,and arm muscle quality,*** proportional hazards models yielded hazard ratios(HRs)and 95%confidence intervals(CIs)for risks of all-cause mortality in relation to muscle mass,strength,and *** during a median follow-up of 3.98 years,739 participants *** HR(95%CI)of all-cause mortality risk was 1.28(1.08–1.51)for low appendicular muscle mass index,1.38(1.16–1.62)for low total muscle mass index,1.68(1.41–2.00)for low grip strength,and 1.41(1.20–1.66)for low arm muscle quality in models adjusted for sociodemographic characteristics,lifestyle factors,and medical *** Low muscle mass,grip strength,and arm muscle quality are all associated with short-term increased risks of mortality,indicating the importance of maintaining normal muscle mass,strength,and quality for general Chinese adults.

关键词： Muscle All-cause mortality Chinese Prospective Muscle mass Muscle strength Muscle quality

在线全文

学校读者我要写书评

暂无评论

原油流量标准检定系统的科学建立

石油工业技术监督 2000年第7期16卷 4-6页

作者：杜怀栋胜利石油管理局技术检测中心流量检定站东营257000

针对目前流量标准检定系统存在的问题，提出了适合我国国情又能符合国际标准、较为科学的流量标准检定系统，从计量管理的角度，阐述了建立系统的重要意义，并提出了实施系统的一些见解。

关键词：原油流量标准检定系统周期检定校准

Development of a prediction model to identify undiagnosed chronic obstructive pulmonary disease patients in primary care settings in China

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2023年第6期136卷 676-682页

作者： Buyu Zhang Dong Sun Hongtao Niu Fen Dong Jun Lyu Yu Guo huaidong du Yalin Chen Junshi Chen Weihua Cao Ting Yang Canqing Yu Zhengming Chen Liming Li on behalf of the China Kadoorie Biobank Collaborative Group Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijing 100191China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina–Japan Friendship HospitalBeijing 100029China National Center for Respiratory Medicine and National Clinical Research Center for Respiratory Diseases Beijing 100029China Institute of Respiratory Medicine Chinese Academy of Medical SciencesBeijing 100007China Peking University Center for Public Health and Epidemic Preparedness and Response Beijing 100191China Key Laboratory of Molecular Cardiovascular Sciences(Peking University) Ministry of EducationBeijing 100191China National Center for Cardiovascular Diseases Fuwai HospitalChinese Academy of Medical SciencesBeijing 100037China Medical Research Council Population Health Research Unit at the University of Oxford Oxford OX37LFUK Clinical Trial Service Unit and Epidemiological Studies Unit Nuffield Department of Population HealthUniversity of OxfordOxford OX37LFUK Maiji Center for Disease Control and Prevention TianshuiGansu 741020China China National Center for Food Safety Risk Assessment Beijing 100022China 不详

Background:At present,a large number of chronic obstructive pulmonary disease(COPD)patients are undiagnosed in ***,this study aimed to develop a simple prediction model as a screening tool to identify patients at risk for ***:The study was based on the data of 22,943 subjects aged 30 to 79 years and enrolled in the second resurvey of China Kadoorie Biobank during 2012 and 2013 in *** stepwisely selected the predictors using logistic regression *** we tested the model validity through P-P graph,area under the receiver operating characteristic curve(AUROC),ten-fold cross validation and an external validation in a sample of 3492 individuals from the Enjoying Breathing Program in ***:The final prediction model involved 14 independent variables,including age,sex,location(urban/rural),region,educational background,smoking status,smoking amount(pack-years),years of exposure to air pollution by cooking fuel,family history of COPD,history of tuberculosis,body mass index,shortness of breath,sputum and *** model showed an area under curve(AUC)of 0.72(95%confidence interval[CI]:0.72-0.73)for detecting undiagnosed COPD patients,with the cutoff of predicted probability of COPD=0.22,presenting a sensitivity of 70.13%and a specificity of 62.25%.The AUROC value for screening undiagnosed patients with clinically significant COPD was 0.68(95%CI:0.66-0.69).Moreover,the ten-fold cross validation reported an AUC of 0.72(95%CI:0.71-0.73),and the external validation presented an AUC of 0.69(95%CI:0.68-0.71).Conclusion:This prediction model can serve as a first-stage screening tool for undiagnosed COPD patients in primary care settings.

关键词： Chronic obstructive pulmonary disease Screening Prediction model China Kadoorie Biobank

Fresh fruit consumption and diabetes: a prospective cohort study of 0.5 million adults in the China Kadoorie Biobank

在线全文

学校读者我要写书评

暂无评论

Fresh fruit consumption and diabetes: a prospective cohort s...

雪旺细胞与聚乳酸/聚羟基乙酸丝相容性的研究

第十二届全国营养科学大会

作者： huaidong du Liming Li Derrick A.Bennett Yu Guo Zheng Bian Junshi Chen Tim Key Rory Collins Richard Peto Zhengming Chen CTSU Nuffield Department of Population HealthUniversity of Oxford Chinese Academy of Medical Sciences School of Public Health Peking University

Background:Several studies in Western populations have observed that a higher consumption of fruit could help to prevent diabetes incidence,but no such beneficial effect has been reported from *** importantly,to date there is little direct evidence about the associations of fruit consumption with mortality and incidence of

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

临床耳鼻咽喉头颈外科杂志 2008年第5期22卷 226-228页

作者：杜怀栋田宏斌周梁田洁复旦大学附属眼耳鼻喉科医院耳鼻咽喉科上海200031

目的:研究雪旺细胞与聚乳酸/聚羟基乙酸(PLGA)丝的生物相容性。方法:应用乳鼠坐骨神经和臂从神经取材进行雪旺细胞培养,经阿糖胞苷抑制成纤维细胞及差数贴壁纯化,传代增殖至一定数量,将雪旺细胞与PLGA丝复合培养,经扫描电镜观察细胞的... 详细信息

目的:研究雪旺细胞与聚乳酸/聚羟基乙酸(PLGA)丝的生物相容性。方法:应用乳鼠坐骨神经和臂从神经取材进行雪旺细胞培养,经阿糖胞苷抑制成纤维细胞及差数贴壁纯化,传代增殖至一定数量,将雪旺细胞与PLGA丝复合培养,经扫描电镜观察细胞的生长情况。结果:雪旺细胞可以在PLGA丝上贴壁生长,随着时间延长,细胞可分裂增殖。结论:雪旺细胞与PLGA丝生物相容性好,可进一步应用于神经修复。

关键词：雪旺细胞聚乳酸/聚羟基乙酸丝生物相容性

Association between fresh fruit consumption and the risk of chronic obstructive pulmonary disease-related hospitalization and death in Chinese adults:A prospective cohort study

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2023年第19期136卷 2316-2323页

作者： Xin Huang Jiachen Li Weihua Cao Jun Lyu Yu Guo Pei Pei Qingmei Xia huaidong du Yiping Chen Yang Ling Rene Kerosi Rebecca Stevens Xujun Yang Junshi Chen Canqing Yu Zhengming Chen Liming Li on behalf of China Kadoorie Biobank Department of Epidemiology and Biostatistics School of Public HealthPeking University Health Science CenterBeijing 100191China Peking University Center for Public Health and Epidemic Preparedness and Response Beijing 100191China Key Laboratory of Molecular Cardiovascular Sciences(Peking University) Ministry of EducationBeijing 100191China National Clinical Research Center for Cardiovascular Diseases Fuwai HospitalChinese Academy of Medical SciencesNational Center for Cardiovascular DiseasesBeijing 100037China National Coordinate Center Chinese Academy of Medical SciencesBeijing 100730China Nuffield Department of Population Health Clinical Trial Service Unit and Epidemiological Studies Unit(CTSU)University of OxfordOxford OX37LFUK Medical Research Council Population Health Research Unit at the University of Oxford Oxford OX37LFUK Maiji Center for Disease Control and Prevention TianshuiGansu 741020China China National Center for Food Safety Risk Assessment Beijing 100022China 不详

Background:Existing evidence suggests that fruit consumption is a significant influencing factor for chronic obstructive pulmonary disease(COPD),but this is unclear in the Chinese *** examined the association of fresh fruit consumption with the risk of COPD-related hospitalization and death in a nationwide,population-based prospective cohort from ***:Between 2004 and 2008,the China Kadoorie Biobank recruited>0.5 million adults aged 30 to 79 years from ten diverse regions across *** excluding individuals diagnosed with major chronic diseases and prevalent COPD,the prospective analysis included 421,428 *** regression was used to calculate the hazard ratios(HRs)for the association between fresh fruit consumption and risk of COPD-related hospitalization and death,with adjustment for established and potential ***:during a mean follow-up of 10.9 years,11,292 COPD hospitalization events and deaths were documented,with an overall incidence rate of 2.47/1000 *** who consumed fresh fruit daily had a 22%lower risk of COPD-related hospitalization and death compared with non-consumers(HR=0.78,95%confidence interval[CI]:0.71-0.87).The inverse association between fresh fruit consumption and COPD-related hospitalization and death was stronger among non-current smokers and participants with normal body mass index(BMI)(18.5 kg/m^(2)≤BMI<24.0 kg/m^(2));the corresponding HRs for daily fresh fruit consumption were 0.78(95%CI:0.68-0.89)and 0.69(95%CI:0.59-0.79)compared with their counterparts,***:High-frequency fruit consumption was associated with a lower risk of COPD in Chinese *** fruit consumption,together with cigarette cessation and weight control,should be considered in the prevention and management of COPD.

关键词： Fresh fruit Chronic obstructive pulmonary disease Smoking Body mass index