检索结果-南通市图书馆

The RNA-binding domain of DCL3 is required for long-distance RNAi signaling

在线全文

学校读者我要写书评

暂无评论

aBIOTECH 2024年第1期5卷 17-28页

作者： Jie Li Bo-Sen Zhang hua-Wei Wu Cheng-Lan Liu Hui-Shan guo Jian-hua Zhao State Key Laboratory of Plant genomics Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Biotic Interactions University of the Chinese Academy of SciencesBeijing 100049China Qilu Zhongke Academy of Modern Microbiology Technology Jinan 250022China

Small RNA(sRNA)-mediated RNA silencing(also known as RNA interference,or RNAi)is a conserved mechanism in eukaryotes that includes RNA degradation,DNA methylation,heterochromatin formation and protein translation *** plants,sRNAs can move either cell-to-cell or systemically,thereby acting as mobile silencing signals to trigger noncell autonomous ***,whether and what proteins are also involved in noncell autonomous silencing have not been *** this study,we utilized a previously reported inducible RNAi plant,PDSi,which can induce systemic silencing of the endogenous PDS gene,and we demonstrated that DCL3 is involved in systemic PDS silencing through its RNA binding *** confirmed that the C-terminus of DCL3,including the predicted RNA-binding domain,is capable of binding short *** affecting RNA binding,but not processing activity,reduced systemic PDS silencing,indicating that DCL3 binding to RNAs is required for the induction of systemic *** mosaic virus infection assays showed that the RNA-binding activity of DCL3 is required for antiviral RNAi in systemically noninoculated *** findings demonstrate that DCL3 acts as a signaling agent involved in noncell autonomous silencing and an antiviral effect in addition to its previously known function in the generation of 24-nucleotide sRNAs.

关键词： RNAi signaling DCL3 RBD RNAs Cucumber mosaic virus

The Capture and Catalytic Conversion of CO_(2) by Dendritic Mesoporous Silica-Based Nanoparticles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第2期7卷 126-151页

作者： Yabin wang Liangzhu huang Songwei Li Chuntai Liu hua He College of Chemistry and Chemical Engineering Yan'an UniversityYan'an 716000China Institute for Triazine Compounds&Hierarchical Porous Materials Yan'an 716000China National Engineering Research Center for Advanced Polymer Processing Technology Key Laboratory of Materials Processing and Mold(Ministry of Education)Zhengzhou UniversityZhengzhou 450002China

Dendritic mesoporous silica nanoparticles own three-dimensional center-radial channels and hierarchical pores,which endows themselves with super-high specific surface area,extremely large pore volumes,especially accessible internal spaces,and so *** guest species(such as organic groups or metal nanoparticles)could be readily decorated onto the interfaces of the channels and pores,realizing the functionalization of dendritic mesoporous silica nanoparticles for targeted *** adsorbents and catalysts,dendritic mesoporous silica nanoparticles-based materials have experienced nonignorable development in CO_(2)capture and catalytic *** comprehensive review provides a critical survey on this pregnant subject,summarizing the designed construction of novel dendritic mesoporous silica nanoparticles-based materials,the involved chemical reactions(such as CO_(2)methanation,dry reforming of CH_(4)),the value-added chemicals from CO_(2)(such as cyclic carbonates,2-oxazolidinones,quinazoline-2,4(1H,3H)-diones),and so *** adsorptive and catalytic performances have been compared with traditional silica mesoporous materials(such as SBA-15 or MCM-41),and the corresponding reaction mechanisms have been thoroughly *** is sincerely expected that the in-depth discussion could give materials scientists certain inspiration to design brand-new dendritic mesoporous silica nanoparticles-based materials with superior capabilities towards CO_(2)capture,utilization,and storage.

关键词： catalytic conversion CO_(2)adsorption CO_(2)capture dendritic mesoporous silica nanoparticles

Improving anammox activity and reactor start-up speed by using CO_(2)/NaHCO_(3) buffer

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第5期139卷 60-71页

作者： Shaoan Cheng huahua Li Xinyuan He hua Chen Longxin Li State Key Laboratory of Clean Energy Utilization College of Energy EngineeringZhejiang UniversityHangzhou 310027China

Anammox bacteria grow slowly and can be affected by large pH *** suitable buffers could make the start-up of anammox reactors easy and *** this study,the effects of three kinds of buffers on the nitrogen removal and growth characteristics of anammox sludge were *** with CO_(2)/NaHCO_(3)buffer solution(CCBS)performed the best in nitrogen removal,while 4-(2-hydroxyerhyl)piperazine-1-ethanesulfonic acid(HEPES)and phosphate buffer solution(PBS)inhibited the anammox *** with 50 mmol/L CCBS could start up in 20 days,showing the specific anammox activity and anammox activity of 1.01±0.10 gN/(gVSS·day)and 0.83±0.06 kgN/(m^(3)·day),*** Kuenenia was the dominant anammox bacteria,with a relative abundance of 71.8%.Notably,anammox reactors could also start quickly by using 50 mmol/L CCBS under nonstrict anaerobic *** findings are meaningful for the quick start-up of engineered anammox reactors and prompt enrichment of anammox bacteria.

关键词： Anammox bacteria Buffer solution CO_(2)/NaHCO_(3) Physiological characteristics Microbial community shift

Enhancing source domain availability through data and feature transfer learning for building power load forecasting

在线全文

学校读者我要写书评

暂无评论

Building Simulation 2024年第4期17卷 625-638页

作者： Fanyue Qian Yingjun Ruan Huiming Lu hua Meng Tingting Xu College of Mechanical and Energy Engineering Tongji UniversityShanghai200092China United Automotive Electronic Systems Co. LtdShanghai201206China

During the initial phases of operation following the construction or renovation of existing buildings,the availability of historical power usage data is limited,which leads to lower accuracy in load forecasting and hinders normal ***,by transferring load data from similar buildings,it is possible to enhance forecasting ***,indiscriminately expanding all source domain data to the target domain is highly likely to result in negative transfer *** study explores the feasibility of utilizing similar buildings(source domains)in transfer learning by implementing and comparing two distinct forms of multi-source transfer ***,this study focuses on the Higashita area in Kitakyushu City,Japan,as the research *** buildings that exhibit the highest similarity to the target buildings within this area were selected for ***,the two-stage TrAdaBoost.R^(2) algorithm is used for multi-source transfer learning,and its transfer effect is ***,the application effects of instance-based(IBMTL)and feature-based(FBMTL)multi-source transfer learning are compared,which explained the effect of the source domain data on the forecasting accuracy in different transfer *** results show that combining the two-stage TrAdaBoost.R^(2) algorithm with multi-source data can reduce the CV-RMSE by 7.23%compared to a single-source domain,and the accuracy improvement is *** the same time,multi-source transfer learning,which is based on instance,can better supplement the integrity of the target domain data and has a higher forecasting ***,IBMTL tends to retain effective data associations and FBMTL shows higher forecasting *** findings of this study,which include the verification of real-life algorithm application and source domain availability,can serve as a theoretical reference for implementing transfer learning in load forecasting.

关键词： building power load multi-source transfer learning two-stage TrAdaBoost.R2 source domain availability

Electrochemical filtration for drinking water purification:A review on membrane materials,mechanisms and roles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第7期141卷 102-128页

作者： Yuying Qi Donghao Li Shixuan Zhang Fengxiang Li Tao hua College of Environmental Science and Engineering Nankai UniversityTianjin 300350China Key Laboratory of Pollution Process and Environmental Criteria Ministry of EducationTianjin 300350China Tianjin Engineering Center of Environmental Diagnosis and Contamination Remediation Tianjin 300350China

Electrochemical filtration can not only enrich low concentrations of pollutants but also produce reactive oxygen species to interact with toxic pollutants with the assistance of a power supply,making it an effective strategy for drinking water *** addition,the application of electrochemical filtration facilitates the reduction of pretreatment procedures and the use of chemicals,which has outstanding potential for maximizing process simplicity and reducing operating costs,enabling the production of safe drinking water in smaller *** recent years,the research on electrochemical filtration has gradually increased,but there has been a lack of attention on its application in the removal of low concentrations of pollutants from low conductivity *** this review,membrane substrates and electrocatalysts used to improve the performance of electrochemical membranes are briefly ***,the application prospects of emerging single-atom catalysts in electrochemical filtration are also ***,several electrochemical advanced oxidation processes coupled with membrane filtration are described,and the related working mechanisms and their advantages and shortcomings used in drinking water purification are ***,the roles of electrochemical filtration in drinking water purification are presented,and the main problems and future perspectives of electrochemical filtration in the removal of low concentration pollutants are discussed.

关键词： Electrochemical filtration Drinking water Conductive membrane Low concentration Electrocatalyst

The Limitations and Ethical Considerations of ChatgPT

在线全文

学校读者我要写书评

暂无评论

Data Intelligence 2024年第1期6卷 201-239页

作者： Shangying hua Shuangci Jin Shengyi Jiang guangdong University of Foreign Studies Guangzhou 510000China

With the advancements of artificial intelligence technology,ChatgPT,a new practice of artificial intelligence,holds immense potential across multiple *** user-friendly human-machine interface,rapid response capabilities,and delivery of high-quality answers have attracted considerable attention and widespread *** by many as a groundbreaking advancement in AI,ChatgPT represents a new milestone in the ***,as with any technological evolution,the emergence of ChatgPT brings not only benefits,but also inevitable security risks and ethical *** paper provides specific information about ChatgPT,including its technology,limitations,ethical issues,governance paths and future ***,we firstly offered a thorough exploration of the technical implementation details of gPT series ***,we provided an intricate analysis elucidating the reasons for limitations and scrutinized the consequential impacts,such as malicious misuse,privacy violation,and so ***,we explore diverse governance paths to mitigate the impacts of ChatgPT and present future *** review aims to equip users with crucial knowledge,facilitating well-informed decision-making,effectively handling of potential challenges in employing ChatgPT,and staying abreast with the rapidly evolving landscape of this technology.

关键词： ChatgPT ChatgPT Technology Limitations Ethical considerations Artificial Intelligence

Regulating the key performance parameters for Hg-based IR NLO chalcogenides via bandgap engineering strategy

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第10期35卷 516-520页

作者： A-Yang wang Sheng-hua Zhou Mao-Yin Ran Xin-Tao Wu hua Lin Qi-Long Zhu State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences (CAS) Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China College of Chemistry Fuzhou University University of Chinese Academy of Sciences

Recently, non-centrosymmetric（NCS） Hg-based chalcogenides have garnered significant interest due to their strong second-harmonic-generation intensities(deff), making them attractive candidates for infrared nonlinear optical（IR-NLO） application. However, achieving both wide band gaps（Eg） and large phasematched deffsimultaneously in these materials remains a challenge due to their inherent constraints on each other. In this research, we have successfully obtained two quaternary NCS Hg-based chalcogenides, Rb2Hgge3S8and Cs2Hgge3S8, by implementing a bandgap engineering strategy that involves alkali metal introduction and Hg/ge ratio regulation. Both compounds consist of 2D [Hg ge3S8]2–anionic layers made of 1D [HggeS6]6–chains and dimeric [ge2S6]4–polyhedra arranged alternately, and the charge-balanced Rb+/Cs+cations located between these layers. Remarkably, Rb2Hgge3S8and Cs2Hgge3S8exhibit overall properties required for promising IR-NLO materials, including sufficient PM deff（0.55–0.70 × AggaS2@2050 nm）, large Eg（3.27–3.41 e V）, giant laser-induced damage thresholds（17.4–19.7 ×AggaS2@1064 nm）, broad optical transmission intervals（0.32–17.5 μm）, and suitable theoretical birefringence（0.069–0.086@2050 nm）. Furthermore, in-depth theoretical analysis reveals that the exceptional IRNLO performance is attributed to the synergy effects of distorted [HgS4] and [geS4] tetrahedra. Our study provides a useful strategy for enhancing the Egand advancing Hg-based IR-NLO materials, which is expected to extended and implemented in other chalcogenide systems.

关键词： Bandgap engineering strategy Hg-based chalcogenides IR nonlinear material Structure-activity relationship Wide energy gap

Evaluation of the value of combined detection of tumor markers CA724,carcinoembryonic antigen,CA242,and CA19-9 in gastric cancer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of gastrointestinal Oncology 2024年第5期16卷 1737-1744页

作者： Chong-Mei Zhou Shao-hua Zhao Department of Clinical Laboratory Henan Provincial People's HospitalZhengzhou 450003Henan ProvinceChina

BACKgROUND gastric cancer is a global health concern that poses a significant threat to human *** To detecting serum changes in carcinoembryonic antigen(CEA),carbohydrate antigens(CA)724,CA242,and CA19-9 expression among patients with gastric *** Eighty patients diagnosed with gastric cancer between January 2020 and January 2023 were included in the observation group,while 80 patients with benign gastric diseases were included in the control *** groups were tested for tumor markers(CA724,CEA,CA242,and CA19-9].Tumor marker indicators(CA724,CEA,CA242,and CA19-9)were compared between the two groups,assessing positive rates of tumor markers across various stages in the observation ***,single and combined detection of various tumor markers were *** The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value observed for the combined detection of CA724,CEA,CA242,and CA19-9 were higher than those of CA724,CEA,CA242,and CA19-9 ***,the combined detection of CA724,CEA,CA242,and CA19-9 has a high diagnostic accuracy and could reduce the occurrence of missed or misdiagnosed cases,facilitating the early diagnosis and treatment of *** CA724,CEA,CA242,and CA19-9 serum levels in gastric cancer patients significantly surpassed those in non-gastric cancer patients(Pgnostic accuracy for gastric cancer,warranting clinical promotion.

关键词： Biomarkers Serum gastric cancer Diagnostic value

Flexible ultrasound arrays with embossed polymer structures for medical imaging

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Semiconductors 2024年第8期45卷 1-3页

作者： Zhongming Chen Qilin hua guozhen Shen School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081China Institute of Flexible Electronics Beijing Institute of TechnologyBeijing 102488China

In recent years,the application of flexible electronic technology[1−3]combined with ultrasonic imaging[4]has blossomed,resulting in a shift in the application place of ultrasonic imaging technology from medical institutions to *** utilization of this application has expanded from the physician’s positioning and guidance to real-time patient monitoring[5],while the range of application scenarios continues to *** transformative changes have made possible through the development of flexible transducer arrays[6,7].*** Xu's team at the University of California San Diego has pioneered the development of various flexible transducer arrays based on island-bridge structures[8]and serpentine electrodes[9].These transducer arrays incorporate rigid 1−3 composite piezoelectric transducers on an island,featuring thin electrodes between the islands to provide mechanical flexibility,metallic electrodes of serpentine structure to provide stretchability of the device,and elastomer materials are used to encapsulate the overall structure,ensuring structural stability and impedance matching to the skin tissue[10].These flexible transducer arrays have found extensive applications in human blood pressure detection[11],cardiac imaging[12],blood flow doppler imaging[13],tissue modulus detection[14],and tissue deep hemoglobin detection[15].

关键词： island matching expanded