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Rare Metals 2021年第11期40卷 3135-3146页

作者： Gang huang Zhi-hua xu Ting-Ting Luo Zhao-Xiong yan Meng Zhang Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education Jianghan UniversityWuhan 430056China Materials Analysis Center Wuhan University of TechnologyWuhan 430070China Hubei Key Laboratory of Industrial Fume and Dust Pollution Control Jianghan UniversityWuhan 430056China

The complete decomposition of formaldehyde(HCHO) at ambient temperature is the most potential strategy for HCHO elimination from indoor ***,extra low content of Pt nanoparticles(0.025 wt%)supported on water-solubility carbon nitride/ceria(Pt/gC_(3)N_(4)@CeO_(2)) was prepared for gaseous HCHO removal at ambient temperature in a simulated indoor *** light(8 W) illumination could visibly boost the complete decomposition of HCHO into CO_(2) over Pt/gC_(3)N_(4)@CeO_(2).The cooperative effect in the distinct heterostructure and plenty of surface reactive oxygen species contribute primarily to the enhanced catalytic performance of Pt/g-C_(3)N_(4)@CeO_(2).Moreover,the possible mechanism of HCHO oxidation over Pt/g-C_(3)N_(4)@CeO_(2) assisted by the fluorescent light irradiation was proposed based on the physicochemical and optical characterization as well as the result of in situ diffuse reflectance infrared Fourier transform *** work might shed some light on the potential application of the versatile catalysts for ambient-temperature catalytic decomposition of HCHO by making full use of the indoor energies.

关键词： Graphitic carbon nitride(g-C3N4) CeO_(2) Catalytic oxidation Formaldehyde decomposition Ambient temperature Fluorescent light irradiation

Advances in the Development of Gradient Scaffolds Made of Nano‑Micromaterials for Musculoskeletal Tissue Regeneration

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Nano-Micro Letters 2025年第3期17卷 455-500页

作者： Lei Fang Xiaoqi Lin Ruian xu Lu Liu Yu Zhang Feng Tian Jiao Jiao Li Jiajia xue Beijing Laboratory of Biomedical Materials Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China School of Biomedical Engineering Faculty of Engineering and ITUniversity of Technology SydneySydneyNSW 2007Australia

The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered *** has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic *** on the anatomical characteristics of bone and interfacial tissues,this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues,specifically focusing on methods used to construct compositional and structural gradients within the *** latest applications of gradient scaffolds for the regeneration of bone,osteochondral,and tendon-to-bone interfaces are ***,the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed,as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2

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Neural Regeneration Research 2025年第6期20卷 1801-1815页

作者： Qing He Zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge xu Gong Chen GHM Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina

Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders. However, a few recent studies have claimed that neural transcription factors cannot convert astrocytes into neurons, attributing the converted neurons to pre-existing neurons mis-expressing transgenes. In this study, we overexpressed three distinct neural transcription factors––NeuroD1, Ascl1, and Dlx2––in reactive astrocytes in mouse cortices subjected to stab injury, resulting in a series of significant changes in astrocyte properties. Initially, the three neural transcription factors were exclusively expressed in the nuclei of astrocytes. Over time, however, these astrocytes gradually adopted neuronal morphology, and the neural transcription factors was gradually observed in the nuclei of neuron-like cells instead of astrocytes. Furthermore,we noted that transcription factor-infected astrocytes showed a progressive decrease in the expression of astrocytic markers AQP4(astrocyte endfeet signal), CX43(gap junction signal), and S100β. Importantly, none of these changes could be attributed to transgene leakage into preexisting neurons. Therefore, our findings suggest that neural transcription factors such as NeuroD1, Ascl1, and Dlx2 can effectively convert reactive astrocytes into neurons in the adult mammalian brain.

关键词： aquaporin-4 Ascl1 astrocyte cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 reprogramming

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao xu xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

Different Patterns of Changes in the Dry Season Diameter at Breast Height of Dominant and Evergreen Tree Species in a Mature Subtropical Forest in South China

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Journal of Integrative Plant Biology 2006年第8期48卷 906-913页

作者： Jun-hua yan Guo-Yi Zhou De-Qiang Zhang xu-Li Tang xu Wang South China Botanical Garden the Chinese Academy of Sciences Guangzhou 510650 China

Information on changes in diameter at breast height （DBH） is important for net primary production （NPP） estimates, timing of forest inventory, and forest management. In the present study, patterns of DBH change were measured under field conditions during the dry season for three dominant and native tree species in a monsoon evergreen broad-leaved forest in the Dinghushan Biosphere Reserve. For each tree species, different patterns of DBH change were observed. In the case of the fast-growing tree species Castanopsis chinensis Hance, large diurnal fluctuations occur, with a peak DBH in the early morning （around 05：00 h） that decreases to a minimum by about 14：00 h. Both Schima superba Gardn. et Chemp and Cryptocarya chinensis （Hance） Hemsh exhibited less diurnal swelling and shrinkage. Diurnal fluctuations for these species were observed on a few occasions over the period of observation. Graphical comparisons and statistical analysis of changes in DBH with meteorological variables indicate that for different trees, the different changes in DBH observed responded to different meteorological variables. Large stem changes were found to occur for Ca. chinensis trees that were associated with variations in solar radiation. However, both S. superba and Cr. chinensis were found to be less sensitive to solar radiation. Changes in the DBH of these two species were found to be controlled mainly by soil temperature and soil moisture. During the later dry season, with a lower soil temperature and soil moisture, all three tree species stopped growing and only negligible shrinkage, expansion, or fluctuation occurred, suggesting that the optimum time to measure tree growth in the Dinghushan Biosphere Reserve is the later dry season.

关键词： dendrometer band diameter at breast height (DBH) Dinghushan meteorological variables subtropical forest.

Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy

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Neural Regeneration Research 2025年第6期20卷 1764-1775页

作者： Zhenzhong Zheng Jialin Chen Jinghong xu Bin Jiang Lei Li Yawei Li Yuliang Dai Bing Wang Department of Spine Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina

Degenerative cervical myelopathy is a common cause of spinal cord injury,with longer symptom duration and higher myelopathy severity indicating a worse *** numerous studies have investigated serological biomarkers for acute spinal cord injury,few studies have explored such biomarkers for diagnosing degenerative cervical *** study involved 30 patients with degenerative cervical myelopathy(51.3±7.3 years old,12 women and 18 men),seven healthy controls(25.7±1.7 years old,one woman and six men),and nine patients with cervical spondylotic radiculopathy(51.9±8.6 years old,three women and six men).Analysis of blood samples from the three groups showed clear differences in transcriptomic *** analysis identified 128 differentially expressed genes that were enriched in patients with neurological *** least absolute shrinkage and selection operator analysis,we constructed a five-gene model(TBCD,TPM2,PNKD,EIF4G2,and AP5Z1)to diagnose degenerative cervical myelopathy with an accuracy of 93.5%.One-gene models(TCAP and SDHA)identified mild and severe degenerative cervical myelopathy with accuracies of 83.3%and 76.7%,*** of two immune cell types(memory B cells and memory-activated CD4^(+)T cells)predicted levels of lesions in degenerative cervical myelopathy with 80%*** results suggest that peripheral blood RNA biomarkers could be used to predict lesion severity in degenerative cervical myelopathy.

关键词： biomarkers candidate genes degenerative cervical myelopathy gene expression analysis immune cell types neurological disabilities peripheral blood RNA profiles spinal cord injury

A New Feature Vector Using Selected Line Spectra for Pulsar Signal Bispectrum Characteristic Analysis and Recognition

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Chinese Journal of Astronomy and Astrophysics 2007年第4期7卷 565-571页

作者： Zhen-hua Xie Lu-Ping xu Guang-Ren Ni yan Wang School of Electronic Engineering Xidian University Xi＇an 710071 National Time Service Center Chinese Academy of Sciences Xi＇ an 710600

Average pulse profiles of pulsar signals are analyzed using the bispectrum technique. The result shows that there are nonlinear phase couplings between the two frequency axes of the bispectrum charts, which indicate nonlinear factors in the generation and propagation of pulsar signals. Bispectra can be used as feature vectors of pulsar signals because of their being translation invariant. A one-dimension selected line spectrum algorithm for extracting pulsar signal characteristic is proposed. Compared with selected bispectra, the proposed selected line spectra have the maximum interclass separability measurements from the point of view of the whole one-dimension feature vector. Recognition experiments on several pulsar signals received at several frequency bands are carried out. The result shows that the selected line spectrum algorithm is suitable for extracting pulsar signal characteristics and has a good classification performance.

关键词： pulsars: general-stars: magnetic fields-stars: fundamental parameters (classification)

Robust SOF Stackelberg game for stochastic LPV systems

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Science China(Information Sciences) 2021年第10期64卷 21-38页

作者： Hiroaki MUKAIDANI hua xu Graduate School of Advanced Science and Engineering Hiroshima University Faculty of Business Sciences The University of Tsukuba

A robust static output feedback（SOF） Stackelberg game with multiple followers in stochastic linear parameter varying（LPV） systems is investigated. The conditions for the existence of a robust SOF Stackelberg strategy set under H;constraints are established by the cross-coupled matrix inequality（CCMI）.To determine this strategy set, the optimization problems corresponding to the relevant cost bounds are defined, and their solution sets are derived using the Karush-Kuhn-Tucker conditions. The results show that the robust SOF Stackelberg strategy set can be obtained by solving higher-order cross-coupled matrix equations（CCMEs）. Because CCMEs are complex and difficult to solve numerically, a heuristic algorithm is developed by combining the CCMEs with the CCMIs. The convergence property is proven using the Krasnoselskii-Mann（KM） iteration algorithm. Finally, two numerical examples are solved to demonstrate the reliability and usefulness of the proposed heuristic algorithm.

关键词： Stackelberg games linear parameter varying (LPV) stochastic systems cross-coupled matrix equations (CCMEs)

Asteroseismic Analysis ofαCen B:Preliminary Tests of Effects of Rotation and Interior Magnetic Field in the Solar-like Star

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Chinese Journal of Astronomy and Astrophysics 2008年第4期8卷 421-432页

作者： yan-Ke Tang Shao-Lan Bi Ning Gai hua-Yin xu National Astronomical Observatories / Yunnan Observatory Chinese Academy of Sciences Kunming650011 China Department of Astronomy Beijing No rrnal University Beijing 100875 China Graduate School of Chinese Academy of Sciences Beijing 100049 China

Taking into consideration the effects of rotation and interior magnetic field during the lifetime of the star, we reconstruct the model of α Cen B to satisfy the latest nonasteroseismic and asteroseismic observational constraints. We find that the effects can induce a change of about 0.3 μHz in the large frequency spacings and can speed up the star＇s evolution. The model of a Cen B has thereby been improved.

关键词： stars oscillations - stars interiors - stars individual (α Cen B)

Influence of on-line tempering parameters on microstructure of medium-carbon steel

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Journal of Iron and Steel Research International 2017年第1期24卷 59-66页

作者： hua Zhang yan-xin Wu Jian-xun Fu Jie xu Qi-jie Zhai State Key Laboratory of Advanced Special Steel Shanghai UniversityShanghai 200072China

A new process involving ultra-fast cooling（UFC）and on-line tempering（OLT）was proposed to displace austempering process,which usually implements in a salt/lead bath and brings out serious pollution in the industrial *** optimization of the new process,involving the evolution of the microstructure of medium-carbon steel during various cooling paths,was *** results show that the cooling path affected the final microstructure in terms of the fraction of pearlite,grain size and distribution of cementite in *** the cooling rate or decreasing the OLT temperature contributes to restraining the transformation from austenite to ferrite,and simultaneously retains more austenite for the transformation of *** is also noted that bainite was observed in the microstructure at the cooling rate of 45℃/s and the OLT temperature of 500℃.Through either increasing the cooling rate or decreasing the OLT temperature,the distribution of cementite in pearlite is more dispersed and grain is *** the possibility of industrial applications into account,the optimal process of cooling at 45℃/s followed by OLT at 600℃ after hot rolling was determined,which achieves a microstructure containing nearly full pearlite with an average grain size of approximately 7μm and a homogeneously dispersed distribution of cementite in pearlite.

关键词： Medium-carbon steel Ultra-fast cooling On-line tempering Phase transformation kinetics