检索结果-南通市图书馆

Lewis Base Catalyzed Selenofunctionalization of Alkynes with Acid-Controlled Divergent Chemoselectivity

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第14期42卷 1623-1629页

作者： ling-ling chen Ren-Fei Cao hua Ke Zhi-Min chen School of Chemistry and Chemical Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral DrugsShanghai Jiao Tong UniversityShanghai200240 China Engineering Technology Research Center for Environmental Protection Materials Pingxiang UniversityPingxiangJiangxi337055 China

Lewis base catalyzed and Brønsted acid controlled chemodivergent electrophilic selenofunctionalizations of alkynes were developed for the first *** selenium-containing tetrasubstituted alkenes were readily obtained in moderate to excellent yields with complete E/Z *** the substrates were 1-ethynyl naphthol derivatives,linear selenium-containing tetrasubstituted alkenes were produced via intermolecular oxygen nucleophilic attack in the absence of acid additive;in contrast,cyclic selenium-containing tetrasubstituted alkenes were generated through intramolecular carbon nucleophilic capture with the addition of Brønsted acid.

关键词： Alkynes Electrophilic addition Chemoselectivity Lewis base catalysis Selenofunctionalization

Advanced Functional Electromagnetic Shielding Materials:A Review Based on Micro‑Nano Structure Interface Control of Biomass Cell Walls

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 98-134页

作者： Yang Shi Mingjun Wu Shengbo Ge Jianzhang Li Anoud Saud Alshammari Jing Luo Mohammed A.Amin hua Qiu Jinxuan Jiang Yazeed M.Asiri Runzhou huang hua Hou Zeinhom M.El‑Bahy Zhanhu Guo Chong Jia Kaimeng Xu Xiangmeng chen Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China State Key Laboratory of Efficient Production of Forest Resourced Beijing Forestry UniversityQinghua East Road 35Haidian DistrictBeijing 100083People’s Republic of China Department of Physics Faculty of Sciences‑ArarNorthern Border UniversityArar 91431Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Integrated Composites Lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024People’s Republic of China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr CityCairo 11884Egypt Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products International Joint Research Center for Biomass MaterialsSouthwest Forestry UniversityKunming 650224People’s Republic of China School of Science Henan Agricultural UniversityZhengzhou 450002People’s Republic of China

Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass *** materials offer numerous advantages such as being lightweight,porous,and *** to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding *** concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding *** particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be *** preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and *** composite methods and fillers of various biomass materials were *** paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.

关键词： Biomass materials Electromagnetic interference shielding Micro-nano structure interface control Conductivity

改良式硅橡胶印模定位平行投照技术的临床应用

在线全文

学校读者我要写书评

暂无评论

口腔医学研究 2019年第6期35卷 611-614页

作者：韩超高安天王铁梅花凌晨李厚轩林梓桐南京大学医学院附属口腔医院南京市口腔医院口腔颌面医学影像科江苏南京210008 南京大学医学院附属口腔医院南京市口腔医院牙周科

目的:探讨改良式硅橡胶印模定位平行投照技术的临床运用。方法:选取24例牙周炎牙周治疗患者及 24例牙体牙髓科根管治疗的患者,分别进行硅橡胶印模定位平行投照和分角线投照,分别测量数字式根尖片上沿牙长轴方向的牙体长度(L)及釉牙骨质... 详细信息

目的:探讨改良式硅橡胶印模定位平行投照技术的临床运用。方法:选取24例牙周炎牙周治疗患者及 24例牙体牙髓科根管治疗的患者,分别进行硅橡胶印模定位平行投照和分角线投照,分别测量数字式根尖片上沿牙长轴方向的牙体长度(L)及釉牙骨质界牙体宽度(W),按照牙位分为前牙+上颌磨牙组和下颌磨牙组,使用SPSS 22.0软件进行配对 t 检验及相关性分析比较2种投照技术2次投照的差异。结果:虽然两种投照技术前后2次投照的牙体长度及宽度的配对 t 检验均不具有显著性差异( P >0.05),但是与分角线投照技术相比,改良式硅橡胶印模定位平行投照技术所得到的前后两次根尖片上的牙体长度和宽度的组内相关系数更高。结论:改良式硅橡胶印模定位投照技术是一种稳定可靠、可操作性强的根尖片投照技术,适用于需要进行纵向定量对比的各类口腔科疾病诊断和分析。

关键词：硅橡胶印模平行投照技术分角线投照技术

High-quality voice conversion system based on GMM statistical parameters and RBF neural network

在线全文

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2014年第5期21卷 68-75,93页

作者： chen Xian-tong ZHANG ling-hua College of Telecommunications and Information Engineering Nanjing University of Posts and Telecommunications

A voice conversion （VC） system was designed based on Gaussian mixture model （GMM） and radial basis function （RBF） neural network. As a voice conversion model, RBF network needs quantities of training data to improve its performance. For one speech, the networks trained by different segments of data have different transformation effects. Since trying segment by segment to obtain the best conversion effect is complex, a conversion method was proposed, that uses GMM for statistics before training RBF network to aim at the problem. The speech transformation and representation using adaptive interpolation of weighted spectrum （STRAIGHT） model is used for accurate extraction of vocal tract spectrum. Then GMM is used to classify the numerous spectral parameters. The obtained mean parameters were trained in RBF network. Experiment reveals that, the soft classification ability of GMM can promptly realize the reduction and classification of training data under the premise of ensuring the training effect. The selection complexity is decreased thereafter. Compared to the conventional RBF network training methods, this method can make the transformation of spectral parameters more effective and improve the quality of converted speech.

关键词： VC system STRAIGHT vocal tract spectrum GMM RBF

在线全文

学校读者我要写书评

暂无评论

超支化有机硅嵌段水性聚氨酯的合成

印染 2017年第1期43卷 11-14页

作者：武迪王海峰管永华张晓玲陈颖徐锦锦南通大学纺织服装学院江苏南通226000

以异佛尔酮二异氰酸酯(IPDI)、端羟基有机硅嵌段聚醚(自制)、二羟甲基丙酸(DMPA)、1,4-丁二醇(BDO)和二乙醇胺(DEA)为主要原料,合成超支化有机硅嵌段水性聚氨酯(LWPU)。以合成产物的自乳化性、—NCO质量分数以及整理后织物性能为评价指... 详细信息

以异佛尔酮二异氰酸酯(IPDI)、端羟基有机硅嵌段聚醚(自制)、二羟甲基丙酸(DMPA)、1,4-丁二醇(BDO)和二乙醇胺(DEA)为主要原料,合成超支化有机硅嵌段水性聚氨酯(LWPU)。以合成产物的自乳化性、—NCO质量分数以及整理后织物性能为评价指标,对端氢硅油相对分子质量、n(LWPU)∶n(DEA)配比、反应时间和加料方式进行优化。结果表明,n(LWPU)∶n(DEA)=3∶1,在反应温度0~5℃,反应时间50 min的条件下,以相对分子质量为2 500的端氢硅油合成的整理剂能均匀分散,且稳定性良好,处理后的织物抗起毛起球性能达到4级,并且手感良好。

关键词：化学整理合成超支化有机硅水性聚氨酯针织物棉

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： Yang-Zheng Lan Zheng Wu Wen-Jia chen Xin-Ning Yu hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

Role of the Greenland Sea ice anomaly in the late-spring drought over Northwest China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atmospheric and Oceanic Science Letters 2025年第1期18卷 1-5页

作者： Yang Liu Huopo chen Nansen-Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of SciencesBeijingChina Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University for Information Science and TechnologyNanjingChina

Drought across Northwest China in late spring has exerted a vital effect on the local climate and agricultural production,and has been alleviated during the past *** study explored the influence of the preceding Arctic sea ice on the May drought in Northwest China caused by the precipitation *** analysis indicated that when the Greenland Sea ice concentration is abnormally high during February to April,the dry conditions in Northwest China tend to be *** increase of sea ice in the Greenland Sea can excite a meridional circulation,which causes sea surface temperature(SST)anomalies in the North Atlantic via the sea-air interaction,manifested as significant warm SST anomalies over the south of Greenland and the subtropical North Atlantic,but negative SST anomalies over the west of the *** abnormal SST pattern maintains to May and triggers a zonal wave train from the North Atlantic through Scandinavia and Central Asia to Northwest China,leading to abnormal cyclones in Northwest ***,Northwest China experiences a more humid climate than usual.

关键词： Arctic sea ice Greenland Sea North Atlantic SST Drought Northwest China

Cell polarization in ischemic stroke: molecular mechanisms and advances

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling chen Danyang chen Gaigai Li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

HPLC法同时测定人血浆中的对乙酰氨基酚、水杨酸和咖啡因的含量

在线全文

学校读者我要写书评

暂无评论

沈阳药科大学学报 2009年第7期26卷 547-550,582页

作者：刘伟卢姗秦峰高桂花陈凌云李发美沈阳药科大学药学院辽宁沈阳110016

目的建立同时测定人血浆中对乙酰氨基酚、水杨酸和咖啡因浓度的HPLC法,并将其应用于阿咖酚胶囊复方制剂的人体药动学研究。方法以甲醇-四氢呋喃-10 mmol.L-1醋酸盐缓冲液(含体积分数为0.1%的冰醋酸溶液)(体积比为23∶2∶77)为流动相,茶... 详细信息

目的建立同时测定人血浆中对乙酰氨基酚、水杨酸和咖啡因浓度的HPLC法,并将其应用于阿咖酚胶囊复方制剂的人体药动学研究。方法以甲醇-四氢呋喃-10 mmol.L-1醋酸盐缓冲液(含体积分数为0.1%的冰醋酸溶液)(体积比为23∶2∶77)为流动相,茶碱为内标,采用krom asil苯基柱分离,在237 nm处进行检测。结果血浆中对乙酰氨基酚、水杨酸和咖啡因测定方法的线性分别为0.203~16.2、0.503~80.4、0.103~8.24μg.L-1;方法的准确度?RE?分别为-4.2%~0.5%、-9.2%^-0.5%、-7.8%~1.9%;日内精密度?RSD?分别小于5.2%、6.5%、7.0%;日间精密度?RSD?分别小于8.1%、5.2%、6.2%。结论建立的HPLC方法可用于阿咖酚胶囊复方制剂的人体药动学研究。

关键词：高效液相色谱法对乙酰氨基酚水杨酸咖啡因药动学