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Study on psychological resilience and associated influencing factors in lung cancer patients with bone metastases

World Journal of Psychiatry 2024年第9期14卷 1326-1334页

作者： Chao-Fan Guo Li-Li wu Zhong-Zhong Peng hua-Long Lin jie-Ni Feng Department of Orthopedics The Third Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325200Zhejiang ProvinceChina Department of Medical Oncology The Third Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325200Zhejiang ProvinceChina Department of Medical Oncology Ningbo Hangzhou Bay HospitalNingbo 315336Zhejiang ProvinceChina

BACKGROUND Evaluating the psychological resilience of lung cancer(LC)patients helps understand their mental state and guides future ***,there is limited research on the psychological resilience of LC patients with bone *** To explore the psychological resilience of LC patients with bone metastases and identify factors that may influence psychological *** LC patients with bone metastases who met the inclusion criteria were screened from those admitted to the Third Affiliated Hospital of Wenzhou Medical *** psychological scores of the enrolled patients were *** were then grouped based on the mean psychological score:Those with scores lower than the mean value were placed in the low-score group and those with scores equal to or greater than the mean value was placed in the high-score *** baseline data(age,gender,education level,marital status,residence,monthly income,and religious beliefs),along with self-efficacy and medical coping mode scores,were *** This study included 142 LC patients with bone metastases admitted to our hospital from June 2022 to December 2023,with an average psychological resilience score of 63.24±9.96 *** grouping,the low-score group consisted of 69 patients,including 42 males and 27 females,with an average age of 67.38±9.55 *** high-score group consisted of 73 patients,including 49 males and 24 females,with a mean age of 61.97±5.00 years.χ2 analysis revealed significant differences between the two groups in education level(χ2=6.604,P=0.037),residence(χ2=12.950,P=0.002),monthly income(χ2=9.375,P=0.009),and medical coping modes(χ2=19.150,P=0.000).Independent sample t-test showed that the high-score group had significantly higher self-efficacy scores(t=3.383,P=0.001)and lower age than the low-score group(t=4.256,P<0.001).Furthermore,multivariate logistic regression hazard analysis confirmed that self-efficacy is an independent protective factor for psy

关键词： Lung cancer Bone metastases Psychological resilience Influencing factors Clinical evaluation

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Iron-Catalyzed Reductive C(aryl)—Si Cross-Coupling of Diaryl Ethers with Chlorosilanes

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Chinese Journal of Chemistry 2024年第6期42卷 578-584页

作者： Pei Liu Baowei wu Xuefeng Cong jie Kong School of Chemistry and Chemical Engineering Northwestern Polytechnical UniversityXi'anShaanxi710072 China Institute of Molecular Plus Department of Chemistry and Haihe Laboratory of Sustainable Chemical TransformationsTianjin University92 Weijin RoadTianjin300072 China

The reductive cross-coupling between C(aryl)—O and Si—Cl bonds is of much importance as a valuable strategy for the construction of C(aryl)—Si bonds but has remained a great ***,we report a reductive cross-coupling of diaryl ethers and chlorosilanes via strong electrophilic C(aryl)—O and Si—Cl bonds cleavage by iron catalysis,which constitutes an efficient protocol for the synthesis of a range of functionalized *** combination of low cost FeCl2 as the precatalyst and iPrMgCl as the reductant shows high activity in the successive cleavage of unactivated C(aryl)—O bonds of diaryl ethers and strong electrophilic Si—Cl bonds of chlorosilanes,allowing their cross-coupling in a reductive *** low-valent iron species generated in situ by reduction of FeCl2 with iPrMgCl was proposed,which prefers to initially cleavage the C(aryl)—O bond of diaryl ethers with the chelation help of an o-amide auxiliary.

关键词： Cross-coupling Diaryl ethers Chlorosilanes C—O bond cleavage Iron catalyst 3d transition metals Selectivity Regioselectivity

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Privacy-Preserving Frank-Wolfe on Shuffle Model

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Acta Mathematicae Applicatae Sinica 2024年第4期40卷 887-907页

作者： Ling-jie ZHANG Shi-song wu Hai ZHANG School of Mathematics Northwest UniversityXi’an 710127China School of Mathematics and Information Science Baoji University of Arts and SciencesBaoji 721013China China Southern Power Grid Artificial Intelligence Technology Company Limited Guangzhou 510700China

In this paper,we design the differentially private variants of the classical Frank-Wolfe algorithm with shuffle model in the optimization of machine *** weak assumptions and the generalized linear loss(GLL)structure,we propose a noisy Frank-Wolfe with shuffle model algorithm(NoisyFWS)and a noisy variance-reduced Frank-Wolfe with the shuffle model algorithm(NoisyVRFWS)by adding calibrated laplace noise under shuffling scheme in thel_(p)(p∈[1,2])-case,and study their privacy as well as utility guarantees for the H?lder smoothness *** particular,the privacy guarantees are mainly achieved by using advanced composition and privacy amplification by *** utility bounds of the Noisy FWS and NoisyVRFWS are analyzed and obtained the optimal excess population risksO(n-(1+α/4α+log(d)√log(1/δ)/n∈and O(n-1+α/4α+log(d)√log1(+δ)/n^(2)∈with gradient complexity O(n(1+α)^(2)/4α^(2)forα∈[1/√3,1].It turns out that the risk rates under shuffling scheme are a nearly-dimension independent rate,which is consistent with the previous work in some *** addition,there is a vital tradeoff between(α,L)-Holder smoothness GLL and the gradient *** linear gradient complexity O(n)is showed by the parameterα=1.

关键词： differential privacy Frank-Wolfe algorithm privacy amplification shuffle model

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Performance Analysis and Optimization of Energy Harvesting Modulation for Multi-User Integrated Data and Energy Transfer

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China Communications 2024年第1期21卷 148-162页

作者： Yizhe Zhao Yanliang wu jie Hu Kun Yang School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Integrated data and energy transfer(IDET)enables the electromagnetic waves to transmit wireless energy at the same time of data delivery for lowpower *** this paper,an energy harvesting modulation(EHM)assisted multi-user IDET system is studied,where all the received signals at the users are exploited for energy harvesting without the degradation of wireless data transfer(WDT)*** joint IDET performance is then analysed theoretically by conceiving a practical time-dependent wireless *** the aid of the AO based algorithm,the average effective data rate among users are maximized by ensuring the BER and the wireless energy transfer(WET)*** results validate and evaluate the IDET performance of the EHM assisted system,which also demonstrates that the optimal number of user clusters and IDET time slots should be allocated,in order to improve the WET and WDT performance.

关键词： energy harvesting modulation(EHM) integrated data and energy transfer(IDET) performance analysis wireless data transfer(WDT) wireless energy transfer(WET)

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Engineering particles towards 3D supraballs-based passive cooling via grafting CDs onto colloidal photonic crystals

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Chinese Chemical Letters 2024年第4期35卷 457-463页

作者： jie wu Xiaoqing Yu Guoxing Li Su Chen State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 210009China

Particle engineering has opened the floodgates to material science in both fundamental and application field. However, covalent interactions have not yet been adequately designed in the particle engineering for functional colloidal photonic crystals(CPCs). Herein, we achieved covalent coupling between carboxylrich poly(styrene-acrylic acid)(P(St-AA)) monodispersed colloidal particles and amine-rich carbon dots(CDs) based on an feasible and universal particle engineering strategy. The designed CDs-grafted P(St-AA)monodispersed colloidal particles initiate a hydrogen bond-driven assembly mode and ensure the construction of large-scale crack-free CPCs. Moreover, the CDs equipped with selective broad-band absorption capacity could improve the saturation of structural colors for high-visibility CPCs. Furthermore, an injectable photonic hydrogel(IPH) is developed to design CPC supraball hydrogel via integrating the CDsgrafted P(St-AA) CPC supraballs with supramolecular hydrogel. Combining superior flexibility, sufficient self-healing capacity of supramolecular hydrogel with visual optical information of our CPC supraballs, a cyclically reversible coding and decoding system was developed. Meanwhile, we firstly demonstrated the novel strategy of 3D supraballs-based passive cooling. The designed 3D CPC supraball hydrogel presents nearly full observation angle reflections behavior and excellent water evaporation capacity and achieves3.6 ℃ temperature drops, showing the application advantages in 3D thermal management. This work not only provides a new insight for manipulating optical properties of CPCs, but also demonstrates an easyto-perform platform, as well as indicates the direction for the promising application of CPCs.

关键词： Particle engineering Carbon dots Colloidal photonic crystals Passive cooling Digital coding

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Experimental investigation about the incipient velocity of spherical particles on a hemispherical bed surface

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Particuology 2024年第5期88卷 49-61页

作者： Chuannan Li jie Chen Changbo Jiang Xie Li Zhiyuan wu School of Hydraulic and Environmental Engineering Changsha University of Science & TechnologyChangsha 410114China Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province Changsha 410114China Key Laboratory of Water-Sediment Sciences and Water Disaster Prevention of Hunan Province Changsha 410114China

The sediment particles play a huge role in shaping the bed load *** this research,240 water-tunnel experiments are carried out to investigate the incipient velocity of the observation particles in two particle *** accurately predict the incipient velocity of the observation particles,the equation is conceived by the rolling instability *** incipient velocity equations and experimental data are used to analyze the trend of dispersive pressure and the effect of arrangement position on *** find that it is appropriate to choose the coefficient of drag as 0.261 and the coefficient of lift as 0.198 for the incipient velocity equation of spherical particles on the hemispherical bed ***,the dispersive pressure is closely related to the flow state,particle size,and particle arrangement,which leads to the incipient velocity of the observation particle being at a minimum when the interference particle angle is 45°.Finally,the particle spacing and the projected area changed with the arrangements,directly affecting the incipient velocity of the observed *** analysis of four aspects for the coefficients,dispersive pressure,different particle spacing,and projected area will facilitate the prediction of particle incipient velocity,especially on hemispherical beds.

关键词： Hemispherical bed surface Observed particle Interference particle Dispersive pressure Incipient velocity

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HSP110 aggravates ischemia-reperfusion injury after liver transplantation by promoting NF-κB pathway

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Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 344-352页

作者： Qing-Zhi Hu Zhen-Rui Cao Wei-Xiong Zheng Min-jie Zhao Jun-hua Gong Cong Chen Zhong-Jun wu Rui Tao Department of Hepatobiliary Surgery Bishan Hospital of Chongqing Medical UniversityChongqing 402760China Department of Cardiothoracic Surgery the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China c Department of Hepatobiliary Surgery the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Hepatobiliary Surgery the Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China

Background:Ischemia-reperfusion injury(IRI)poses a significant challenge to liver transplantation(LT).The underlying mechanism primarily involves overactivation of the immune *** shock protein 110(HSP110)functions as a molecular chaperone that helps stabilize protein ***:An IRI model was established by performing LT on Sprague-Dawley rats,and HSP110 was silenced using ***-eosin staining,TUNEL,immunohistochemistry,ELISA and liver enzyme analysis were performed to assess IRI following *** blotting and quantitative reverse transcription-polymerase chain reaction were conducted to investigate the pertinent molecular ***:Our findings revealed a significant increase in the expression of HSP110 at both the mRNA and protein levels in the rat liver following LT(P<0.05).However,when rats were injected with siRNAHSP110,IRI subsequent to LT was notably reduced(P<0.05).Additionally,the levels of liver enzymes and inflammatory chemokines in rat serum were significantly reduced(P<0.05).Silencing HSP110 with siRNA resulted in a marked decrease in M1-type polarization of Kupffer cells in the liver and downregulated the NF-κB pathway in the liver(P<0.05).Conclusions:HSP110 in the liver promotes IRI after LT in rats by activating the NF-κB pathway and inducing M1-type polarization of Kupffer *** HSP110 to prevent IRI after LT may represent a promising new approach for the treatment of LT-associated IRI.

关键词： Ischemia-reperfusion injury Liver transplantation Inflammation HSP110 Heat shock proteins NF-κB

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A novel Ag/ZnO core-shell structure for efficient sterilization synergizing antibiotics and subsequently removing residuals

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Green Energy & Environment 2024年第2期9卷 366-377页

作者： Wenmei Han Wenli Wang jie Fan Runping Jia Xuchun Yang Tong wu Qingsheng wu School of Chemical Science and Engineering Shanghai Key Laboratory of Chemical Assessment and SustainabilityInstitute of Advanced StudyTongji UniversityShanghai200092China College of Textile and Clothing Engineering China National Textile and Apparel Council Key Laboratory of Natural DyesSoochow UniversitySuzhou215123China Department of Urology Shanghai First People’s HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai200080China School of Materials Science and Engineering Shanghai Institute of TechnologyShanghai201418China

The massive use of antibiotics has led to the aggravation of bacterial resistance and also brought environmental pollution *** poses a great threat to human *** the dosage of antibiotics is reduced by increasing its bactericidal performance,the emergence of drug resistance is certainly delayed,so that there's not enough time for developing drug resistance during ***,we selected typical representative materials of metal Ag and semiconductor ZnO nano-bactericides to design and synthesize Ag/ZnO hollow core-shell structures(AZ for short).Antibiotics are grafted on the surface of AZ through rational modification to form a composite sterilization *** research results show that the antibacterial efficiency of the composite system is significantly increased,from the sum(34.7%+22.8%-57.5%)of the antibacterial efficiency of AZ and gentamicin to 80.2%,net synergizes 22.7%,which fully reflects the effect of 1+1>***,the dosage of antibiotics can be drastically reduced in this way,which makes both the possibility of bacterial resistance and medical expenses remarkably ***,residual antibiotics can be degraded under simple illumination using AZ-self as a photocatalyst,which cuts off the path of environmental *** short,such an innovative route has guiding significance for drug resistance.

关键词： Ag/ZnO hollow Core-shell structures Antibiotics Gentamycin Synergistic sterilization Photodegradation

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Monte Carlo Simulation-Based Robust Workflow Scheduling for Spot Instances in Cloud Environments

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Tsinghua Science and Technology 2024年第1期29卷 112-126页

作者： Quanwang wu Jianzhao Fang jie Zeng Junhao Wen Fengji Luo College of Computer Science Chongqing UniversityChongqing 400044China National Experimental Teaching Demonstration Center Chongqing UniversityChongqing 400044China College of Big Data and Software Engineering Chongqing UniversityChongqing 400044China School of Civil Engineering The University of SydneySydney 2006Australia

When deploying workflows in cloud environments,the use of Spot Instances(SIs)is intriguing as they are much cheaper than on-demand ***,Sls are volatile and may be revoked at any time,which results in a more challenging scheduling problem involving execution interruption and hence hinders the successful handling of conventional cloud workflow scheduling *** some scheduling methods for Sls have been proposed,most of them are no more applicable to the latest Sls,as they have evolved by eliminating bidding and simplifying the pricing *** study focuses on how to minimize the execution cost with a deadline constraint when deploying a workflow on volatile Sls in cloud *** on Monte Carlo simulation and list scheduling,a stochastic scheduling method called MCLS is devised to optimize a utility function introduced for this *** the Monte Carlo simulation framework,MCLS employs sampled task execution time to build solutions via deadline distribution and list scheduling,and then returns the most robust solution from all the candidates with a specific evaluation mechanism and selection *** results show that the performance of MCLS is more competitive comparedwithtraditionalalgorithms.

关键词： constrained optimization Monte Carlo simulation robustness Spot Instances(Sls) workflow scheduling

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In Situ Reconfiguration of Assembling Pattern for Modular Continuum Robots

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Journal of Bionic Engineering 2024年第4期21卷 1695-1706页

作者： jie Zhang Jiannan Cai Ke Ma Jinzhao Yang Zhigang wu Haijun Peng Jianing wu School of Mechanical Engineering Dalian University of TechnologyDalian116024People’s Republic of China School of Advanced Manufacturing Sun Yat-Sen UniversityShenzhen518107People’s Republic of China School of Aeronautics and Astronautics Sun Yat-Sen UniversityShenzhen518107People’s Republic of China

Modular continuum robots possess significant versatility across various scenarios;however,conventional assembling methods typically rely on linear connection between *** limitation can impede the robotic interaction capabilities,especially in specific engineering ***,inspired by the assembling pattern between the femur and tibia in a human knee,we proposed a multidirectional assembling *** strategy encompasses linear,oblique,and orthogonal connections,allowing a two-module continuum robot to undergo in-situ reconfiguration into three distinct initial *** anticipate the final configuration resulting from diverse assembling patterns,we employed the positional formulation finite element framework to establish a mechanical model,and the theoretical results reveal that our customizable strategy can offer an effective route for robotic *** showcased diverse assembling patterns for coping with interaction *** experimental results indicate that our modular continuum robot not only reconfigures its initial profile in situ but also enables on-demand regulation of the final *** capabilities provide a foundation for the future development of modular continuum robots,enabling them to be adaptable to diverse environments,particularly in unstructured surroundings.

关键词： Assembling patterns Continuum robot In-situ reconfiguration Tensegrity structure Varying stiffness

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