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Meta-analysis of electrical stimulation promoting recovery of gastrointestinal function after gynecological abdominal surgery

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World Journal of Gastrointestinal Surgery 2024年第11期16卷 3559-3567页

作者： Xue-Xia huang Hui-Feng Gu ping-hua shen Bo-Liang Chu Ying Chen Department of Obstetrics Huzhou Maternal and Child Health HospitalHuzhou 313000Zhejiang ProvinceChina Department of Nursing Huzhou Maternal and Child Health HospitalHuzhou 313000Zhejiang ProvinceChina Department of Gynaecology Huzhou Maternal and Child Health HospitalHuzhou 313000Zhejiang ProvinceChina

BACKGROUND The effects of electrical stimulation on gastrointestinal function recovery after gynecological abdominal surgery was not *** To systematically evaluate the effects of electrical stimulation on gastrointestinal function recovery after gynecological abdominal *** The Cochrane Library,Web of Science,PubMed,ProQuest,and the Chinese bio-medical literature databases Wanfang,Weipu,and CNKI were used to search for relevant studies on controlled trials of electrical stimulation in gynecological abdominal surgery patients from self-established databases to May *** RevMan software(version 5.3)was used to analyze the included literature and explore the heterogeneity of each *** Seven controlled trials,involving 520 patients,were *** results of meta-analysis showed that electrical stimulation could shorten the recovery time of intestinal sound after gynecological abdominal surgery[odds ratio(OR):-5.11,95%CI:-5.84 to-4.38,P<0.00001]and improve the time of first anal exhaust(OR:-1.19,95%CI:-1.38 to-0.99,P<0.00001),improved the time of first anal defecation(OR:-0.98,95%CI:-1.19 to-0.78,P<0.00001),The difference is *** to the funnel plot,if the scatter is symmetrical,it indicates that the funnel plot is *** Electrical stimulation can shorten this reduces the length of time it takes for the patient to recover from bowel sounds and also affects the time to first anal voiding and defecation to some extent,thereby promoting gas-trointestinal function recovery after gynecological abdominal *** quality of the studies included in this review was poor,which may have affected the final *** is necessary to conduct a randomized controlled study with higher quality and more samples to further confirm the promoting effect of electrical stimulation on gastrointestinal function recovery to guide clinical treatment.

关键词： Electrical stimulation Gynecology Abdominal surgery Gastrointestinal function Meta-analysis

NEW ORGANIC NONLINEAR OPTICAL MATERIALS OF CINNAMYLIDENE-ACETOPHENONE DERIVATIVES

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Chinese Chemical Letters 1993年第8期4卷 719-720页

作者： Yang CAO Ai hua YUAN Xiao ping shen Chemistry Department,Suzhou University,Suzhou,215006Wen Jian CHEN Chang Qing LIU Chemistry Department,Yangzhou Teachers College,Yangshou,225002

we have synthesised a series of new optically nonlinear organic materials of cinnamylidene-acetophenone derivatives which have large nonl inear optical susceptibilities and short cut-off wavelengths.

关键词： SHG der NEW ORGANIC NONLINEAR OPTICAL MATERIALS OF CINNAMYLIDENE-ACETOPHENONE DERIVATIVES

Clinical anlyisis of Laparoscopic cholecystectomy in patients with previous gastrectomy

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Clinical anlyisis of Laparoscopic cholecystectomy in patient...

Calcium Distribution in Escherichia coli Competent Cells

2015年浙江省外科学学术年会暨国家级肝胆胰疾病诊治进展学习班

作者： Ming-Jie Zhang Qiang Yan Guo-Lei Zhang Si-Yu Zhou Wen-Bin Yuan hua-ping shen Department of General surgery The Central Hospital of Huzhou

Purpose:Previous gastrectomy has been considered a relative contraindication to laparoscopic cholecystectomy(LC).The aim of this study was to identify introducing preoperative evaluation procedure and special laparoscopic surgery techniques to improve the safety and efficacy of LC and investigate the possible risk factors which leading to severe cholecyst morbidity in the patients with previous *** and Methods:The clinical data of 1022 patients administering LC in our hospital were reviewed retrospectively from Jan,1,2010 to May,1,2015,27 patients(2.6%) had undergone previous *** introduced preoperative evaluation procedure and laparoscopic surgery techniques to administer LC in the patients with previous gastrectomy and compared the clinical outcomes to those without previous *** compared patients’ characteristics and clinical details to different severity degree of cholecyst morbidity in the patients with previous ***:The operative time was significantly longer(p0.05).The patients whose pathology type is malignant,combined with diabetes mullitus or hypercholesteremia,administering Billroth II gastroenterostomy or esophagusenterostomy,the cholecystitis attack frequency,gallstone formation time from first operation,gallbladder polyp combination rate and pancreatitis combination rate were more than the negative group(p<0.05).Conclusion:The comprehensive preoperative evaluation and appropriate surgical techniques are necessary to improve the safety and efficacy of LC in patients with previous *** the possible risk factors can reduce the occurrences of cholecyste morbidity in patients with previous gastrectomy.

关键词： gastrectomy gallbladder disease Laparoscopic cholecystectomy(LC)

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Calcium Distribution in Escherichia coli Competent Cells

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

湖北省遗传学会第七次代表大会暨学术讨论会

作者： Zhi-Xiong Xie Jian-Hong Ou Wen-hua Li ping shen (College of Life Sciences, Wuhan University, Wuhan, Hubei 430072)

关键词： Escherichia coil competence calcium distribution potassium pyroantimonate

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai Xu Zhen Gu hua Yan Dingding shen Xiaosong Gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

快速康复外科对肝胆外科手术患者炎性因子、胃肠激素及胃肠功能的影响

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世界华人消化杂志 2019年第5期27卷 305-310页

作者：周轼瑜慎华平张国雷孙诚湖州市中心医院普外科浙江省湖州市313000

背景肝胆外科手术因复杂的生理与组织解剖结构,手术难度及风险较大,患者会出现强烈的应激反应,影响手术的顺利进行及术后康复效果.快速康复外科通过运用各种经循证医学证实的有效措施,加强围术期过程管理,应用于肝胆外科手术效果值得肯... 详细信息

背景肝胆外科手术因复杂的生理与组织解剖结构,手术难度及风险较大,患者会出现强烈的应激反应,影响手术的顺利进行及术后康复效果.快速康复外科通过运用各种经循证医学证实的有效措施,加强围术期过程管理,应用于肝胆外科手术效果值得肯定.但目前还少有从炎性因子、胃肠激素展开比较的文献报道.本研究以炎性因子、胃肠激素为切入点,分析快速康复外科对肝胆外科手术患者胃肠功能的影响的可能作用机制.目的探讨快速康复外科对肝胆外科手术患者炎性因子、胃肠激素及胃肠功能的影响.方法选择2017-05/2018-04拟行肝胆外科手术患者126例为研究对象,随机分为干预组和对照组各63例.对照组给予常规手术管理方法 ,干预组给予快速康复外科管理方法 ,比较两组患者血清炎性因子、胃肠激素、胃肠功能恢复时间、并发症等指标.结果干预组患者血清肿瘤坏死因子-α、C反应蛋白、白细胞介素-6含量明显低于对照组[(36.20±5.32 vs43.55±6.12) pg/mL,(12.42±2.35 vs18.65±3.24) mg/L,(10.24±2.10 vs15.04±2.32)pg/L],差异有统计学意义(t=7.194, 12.355, 12.175, P<0.05, P<0.01);血清胃动素、胃泌素含量明显高于对照组(205.45±25.16vs168.24±24.25,124.32±24.15 vs104.36±20.42)pg/mL,差异有统计学意义(t=8.452,5.009, P <0.05,P <0.01);肠鸣音恢复时间、肛门排气时间、首次排便时间、术后住院时间明显短于对照组[(16.45±3.12 vs21.24±3.65) h,(20.34±4.54 vs41.25±6.12) h,(38.65±5.24 vs57.42±7.15) h,(9.21±1.32 vs13.54±2.12) d)],差异有统计学意义(t=7.918, 21.780, 18.607,13.762, P <0.05, P <0.01);切口感染等并发症9.52%明显低于对照组26.98%(χ~2=6.436, P <0.05).结论快速康复外科有助于促进肝胆外科手术患者胃肠功能恢复,减少并发症的发生,可能与抑制炎症反应、调节胃肠激素等因素有关.

关键词：肝胆外科快速康复外科炎性因子胃肠激素胃肠功能

喷吹焦炉煤气对COREX竖炉还原的影响研究

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科学技术与工程 2016年第34期16卷 32-37页

作者：张哲铠吴胜利鲁华杜开平沈炜北京科技大学冶金与生态工程学院北京100083

为降低COREX的固体燃料消耗,焦炉煤气(COG)作为一种清洁、高热值能源被引入到COREX炉中,以替代原有的循环冷却煤气。计算了不喷吹焦炉煤气、喷吹焦炉煤气以取消冷却煤气和喷吹焦炉煤气以取消冷却煤气和过剩煤气(完全取消煤气冷却)三种... 详细信息

为降低COREX的固体燃料消耗,焦炉煤气(COG)作为一种清洁、高热值能源被引入到COREX炉中,以替代原有的循环冷却煤气。计算了不喷吹焦炉煤气、喷吹焦炉煤气以取消冷却煤气和喷吹焦炉煤气以取消冷却煤气和过剩煤气(完全取消煤气冷却)三种情况下入竖炉煤气的成分,并通过实验室模拟试验,对焦炉煤气中的甲烷在竖炉中的行为和含铁炉料还原情况进行研究。结果甲烷在竖炉中存在少量的分解,竖炉喷吹焦炉煤气会降低含铁炉料还原。

关键词： COREX 竖炉焦炉煤气还原

脂质转移蛋白SiLTP1基因参与谷子耐盐响应初探

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作物学报 2025年第1期51卷 58-67页

作者：孟凡花刘敏沈傲刘炜山东省农业科学院农作物种质资源研究所山东济南250100 上海应用技术大学生态技术与工程学院上海201418

土壤盐渍化严重制约农业生产发展,通过提高植物耐盐性进行盐碱地综合利用,对于保障粮食安全,提升农业生产效率具有重要意义。脂质转移蛋白是一类在高等植物中广泛存在的小分子蛋白质,能够参与植株生长、信号转导以及多种生物和非生物胁... 详细信息

土壤盐渍化严重制约农业生产发展,通过提高植物耐盐性进行盐碱地综合利用,对于保障粮食安全,提升农业生产效率具有重要意义。脂质转移蛋白是一类在高等植物中广泛存在的小分子蛋白质,能够参与植株生长、信号转导以及多种生物和非生物胁迫过程。前期本课题组克隆到一个谷子中编码脂质转移蛋白的基因SiLTP1,本研究通过构建其原核表达载体和植物双元过表达载体,获得了该基因的原核表达蛋白及同源转化过表达阳性植株,经进一步筛选获得4个纯合株系。体外耐盐性试验显示, SiLTP1的原核表达蛋白具有一定耐盐性;转基因植株苗期耐盐生理指标测定显示,SiLTP1过表达植株在遭受盐胁迫时,植株体内MDA积累减少,抗氧化酶含量升高,可积累更少的过氧化氢,从而降低胁迫对植株的氧化损伤,显示基因过表达植株具有更好的耐盐性。本研究结果初步揭示, SiLTP1可正向调控谷子的耐盐性,其在谷子耐盐抗逆方面具有潜在功能,为耐盐谷子品种改良及新品种培育提供了理论基础和候选基因资源。

关键词：脂质转移蛋白 SiLTP1 盐胁迫谷子耐盐响应

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang shen Su-hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin