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Ocular hypertension and severe intraocular pressure elevation after posterior subtenon injection of triamcinolone acetonide for various diseases

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 946-951页

作者： Yun-Hsiang Yang hua-hsuan kuo Wei-Cherng Hsu Yi-Ting Hsieh Department of Ophthalmology Taipei Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationNew Taipei 231TaiwanChina School of Medicine Tzu Chi UniversityHualien 970TaiwanChina Department of Ophthalmology National Taiwan University HospitalTaipei 10002TaiwanChina

AIM:To evaluate and compare the incidences of ocular hyper tension and severe intraocular pressure(IOP)elevation after posterior subtenon injection of triamcinolone acetonide(PSTA)for various ***:Totally 179 eyes that had received PSTA for diabetic macular edema(n=108),pseudophakic cystoid macular edema(n=20),branch retinal vein occlusion(n=16),central retinal vein occlusion(CRVO,n=14),choroidal neovascularization(n=14)or noninfectious uveitis(n=7)were retrospectively *** primary outcomes included ocular hypertension defined as an IOP>21 mm Hg,and severe IOP elevation defined as a rise of 10 mm Hg or more in IOP compared with *** regression models were used to analyze the hazard ratios(HRs)among different ***:After PSTA,the mean IOPs from month 1 to month 6 all significantly increased(P<0.05).Ocular hypertension occurred in 30.7%of eyes(median time:8 wk),and severe IOP elevation occurred in 16.2%of eyes(median time:9 wk).Patients receiving PSTA for CRVO or uveitis had a significantly higher risk for ocular hypertension(HR=3.049,P=0.004 for CRVO;HR=5.464,P=0.019 for uveitis)and severe IOP elevation(HR=2.913,P=0.034 for CRVO;HR=7.650,P=0.009 for uveitis).CONCLUSION:IOP significantly increases within 6 mo after PSTA,with the onset of ocular hypertension happening mostly at 2 to 3 *** of CRVO or noninfectious uveitis have a higher risk of ocular hypertension or severe IOP elevation after PSTA and should be monitored for IOP more carefully.

关键词： intraocular pressure ocular hypertension uveitis retinal vein occlusion triamcinolone acetonide

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Constrained reinforcement learning with statewise projection: a control barrier function approach

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Science China(Information Sciences) 2024年第3期67卷 136-154页

作者： Xinze JIN kuo LI Qingshan JIA Department of Automation Tsinghua University

Safety is a critical issue for reinforcement learning(RL), as it may be risky for some actual applications if the learning process involves unsafe exploration. Instead of formulating constraints as expectationbased in constrained RL, considering statewise safety in constrained RL is more meaningful. This work aims to address the issue of safe projection in RL by introducing a control barrier function that inherently learns a safe policy through a set certificate. We seek to analyze some theoretical properties of safe projection in the learning process, including convergence and performance bound, and extend the discussion into ensembles and guided controllers. Moreover, we approach analytical solutions for deterministic and stochastic system dynamics. Experimental results in different tasks show that the proposed method achieves better effects in terms of both performance and safety.

关键词： reinforcement learning safe projection control barrier function

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Research progress and prospect of low-carbon biological technology for nitrate removal in wastewater treatment

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 1-21页

作者： Ru Zheng kuo Zhang Lingrui Kong Sitong Liu College of Environmental Sciences and Engineering Peking UniversityBeijing 100871China Key Laboratory of Water and Sediment Sciences Ministry of Education of ChinaBeijing 100871China Eco-Environment and Resource Efficiency Research Laboratory School of Environment and EnergyPeking University Shenzhen Graduate SchoolShenzhen 518055China

Wastewater treatment plants are the major energy consumers and significant sources of greenhouse gas emissions,among which biological nitrogen removal of wastewater is an important contributor to carbon ***,traditional heterotrophic denitrification still has the problems of excessive residual sludge and the requirement of external carbon ***,the development of innovative low-carbon nitrate removal technologies is *** review outlines the key roles of sulfur autotrophic denitrification and hydrogen autotrophic denitrification in low-carbon wastewater *** discovered nitrate/nitrite dependent anaerobic methane oxidation enables sustainable methane emission reduction and nitrogen removal by utilizing available methane in *** microorganisms exhibited a promising potential to achieve carbon-negative nitrate ***,the algal-bacterial symbiosis system and photogranules offer effective and prospective low-carbon options for nitrogen ***,the emerging nitrate removal technology of photoelectrotrophic denitrification and the underlying,photoelectron transfer mechanisms are ***,we summarize and prospect these technologies,highlighting that solar-driven biological nitrogen removal technology is a promising area for future sustainable wastewater *** review has important guiding significance for the design of low-carbon wastewater treatment systems.

关键词： Carbon emissions Low-carbon Biological nitrogen removal Denitrification

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Converting an O-vacancy-rich oxide into a multifunctional separator modifier for long-lifespan lithium metal batteries

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Journal of Energy Chemistry 2024年第10期97卷 371-378页

作者： Juntao Si Xiaoying Li Yixuan Li kuo Cao Yiran Zhu Chunhua Chen CAS Key Laboratory of Precision and Intelligent Chemistry Department of Materials Science and Engineering University of Science and Technology of China

The lithium metal anode is hailed as the desired "holy grail" for the forthcoming generation of highenergy-density batteries,given its astounding theoretical capacity and low ***,the formation and growth of dendrites seriously compromise battery life and ***,an yttriastabilized bismuth oxide（YSB） layer is fabricated on the polypropylene（PP） separator,where YSB reacts with Li anode in-situ in the cell to form a multi-component composite interlayer consisting of Li3Bi,Li2O,and *** interlayer can function not only as a redistributor to regulate Li+distribution but also as an anion adsorber to increase the Li+transference number from 0.37 to 0.79 for suppressing dendrite nucleation and ***,compared with the cell with a baseline separator,those with modified separators exhibit prolonged lifespan in both Li/Li symmetrical cells and Li/Cu ***,the full cells coupled with ultrahigh-loading LiFePO4display an excellent cycling performance of 1700 cycles with a high capacity retention of ～80% at 1 C,exhibiting great potential for practical *** work provides a feasible and effective new strategy for separator modification towards building a much-anticipated dendrite-free Li anode and realizing long-lifespan lithium metal batteries.

关键词： Conversion-alloying reaction Dendrite-free Lithium metal battery Multifunctional interlayer Separator

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Novel variants in DNAH6 cause male infertility associated with multiple morphological abnormalities of the sperm flagella(MMAF)and ICSI outcomes

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Asian Journal of Andrology 2024年第1期26卷 91-98页

作者： Zhong-Mei Shao Yu-Tong Zhu Meng Gu Sen-Chao Guo Hui Yu kuo-kuo Li Dong-Dong Tang Yu-Ping Xu Ming-Rong Lv Reproductive Medicine Center Department of Obstetrics and Gynecologythe First Affiliated Hospital of Anhui Medical UniversityHefei 230022China Department of Obstetrics and Gynecology Fuyang Hospital of Anhui Medical UniversityFuyang 236112China NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract(Anhui Medical University) Hefei 230032China Key Laboratory of Population Health Across Life Cycle(Anhui Medical University) Ministry of Education of the People'sRepublicof ChinaHefei 230032China

Variations in the dynein axonemal heavy chain gene,dynein axonemal heavy chain 6(DNAH6),lead to multiple morphological abnormalities of the *** studies have reported that these deficiencies may result in sperm head ***,whether DNAH6 is also involved in human acrosome biogenesis remains *** purpose of this study was to investigate DNAH6 gene variants and their potential functions in the formation of defective sperm heads and ***-exome sequencing was performed on a cohort of 375 patients with asthenoteratozoospermia from the First Affiliated Hospital of Anhui Medical University(Hefei,China).Hematoxylin and eosin staining,scanning electron microscopy,and transmission electron microscopy were performed to analyze the sperm morphology and *** staining and Western blot analysis were conducted to examine the effects of genetic *** identified three novel deleterious variants in DNAH6 among three unrelated *** absence of inner dynein arms and radial spokes was observed in the sperm of patients with DNAH6 ***,deficiencies in the acrosome,abnormal chromatin compaction,and vacuole-containing sperm heads were observed in these patients with DNAH6 *** decreased levels of the component proteins in these defective structures were further confirmed in sperm from patients with DNAH6 variants using Western *** intracytoplasmic sperm injection(ICSl)treatment,the partner of one patient with a DNAH6 variant achieved successful ***,novel variants in DNAH6 genes that contribute to defects in the sperm head and flagella were identified,and the findings indicated Icsl as an effective clinical treatment for such patients.

关键词： asthenoteratospermia DNAH6 intracytoplasmic sperm injection male infertility

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SG-NeRF:Sparse-Input Generalized Neural Radiance Fields for Novel View Synthesis

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Journal of Computer Science & Technology 2024年第4期39卷 785-797页

作者： kuo Xu Jie Li Zhen-Qiang Li Yang-Jie Cao School of Cyber Science and Engineering Zhengzhou UniversityZhengzhou 450002China Intelligent Big Data System(iBDSys)Lab Shanghai Jiao Tong UniversityShanghai 200240China School of Computer and Artificial Intelligence Zhengzhou UniversityZhengzhou 450001China

Traditional neural radiance fields for rendering novel views require intensive input images and pre-scene optimization,which limits their practical *** propose a generalization method to infer scenes from input images and perform high-quality rendering without pre-scene optimization named SG-NeRF(Sparse-Input Generalized Neural Radiance Fields).Firstly,we construct an improved multi-view stereo structure based on the convolutional attention and multi-level fusion mechanism to obtain the geometric features and appearance features of the scene from the sparse input images,and then these features are aggregated by multi-head attention as the input of the neural radiance *** strategy of utilizing neural radiance fields to decode scene features instead of mapping positions and orientations enables our method to perform cross-scene training as well as inference,thus enabling neural radiance fields to generalize for novel view synthesis on unseen *** tested the generalization ability on DTU dataset,and our PSNR(peak signal-to-noise ratio)improved by 3.14 compared with the baseline method under the same input *** addition,if the scene has dense input views available,the average PSNR can be improved by 1.04 through further refinement training in a short time,and a higher quality rendering effect can be obtained.

关键词： Neural Radiance Fields(NeRF) multi-view stereo(MVS) new view synthesis(NVS)

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Optimal Shape Factor and Fictitious Radius in the MQ-RBF:Solving Ill-Posed Laplacian Problems

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 3189-3208页

作者： Chein-Shan Liu Chung-Lun kuo Chih-Wen Chang Center of Excellence for Ocean Engineering Taiwan Ocean UniversityKeelung202301TaiwanChina Department of Mechanical Engineering National United UniversityMiaoli36063TaiwanChina

To solve the Laplacian problems,we adopt a meshless method with the multiquadric radial basis function(MQRBF)as a basis whose center is distributed inside a circle with a fictitious radius.A maximal projection technique is developed to identify the optimal shape factor and fictitious radius by minimizing a merit function.A sample function is interpolated by theMQ-RBF to provide a trial coefficient vector to compute the merit *** can quickly determine the optimal values of the parameters within a preferred rage using the golden section search *** novel method provides the optimal values of parameters and,hence,an optimal MQ-RBF;the performance of the method is validated in numerical ***,nonharmonic problems are transformed to the Poisson equation endowed with a homogeneous boundary condition;this can overcome the problem of these problems being *** optimal MQ-RBF is extremely *** further propose a novel optimal polynomial method to solve the nonharmonic problems,which achieves high precision up to an order of 10^(−11).

关键词： Laplace equation nonharmonic boundary value problem Ill-posed problem maximal projection optimal shape factor and fictitious radius optimal MQ-RBF optimal polynomial method

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A highly reliable encoding and decoding communication framework based on semantic information

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Digital Communications and Networks 2024年第3期10卷 509-518页

作者： Yichi Zhang Haitao Zhao kuo Cao Li Zhou Zhe Wang Yueling Liu Jibo Wei College of Electronic Science and Technology National University of Defense TechnologyChangsha 410073China

Increasing research has focused on semantic communication,the goal of which is to convey accurately the meaning instead of transmitting symbols from the sender to the *** this paper,we design a novel encoding and decoding semantic communication framework,which adopts the semantic information and the contextual correlations between items to optimize the performance of a communication system over various *** the sender side,the average semantic loss caused by the wrong detection is defined,and a semantic source encoding strategy is developed to minimize the average semantic *** further improve communication reliability,a decoding strategy that utilizes the semantic and the context information to recover messages is proposed in the *** simulation results validate the superior performance of our strategies over state-of-the-art semantic coding and decoding policies on different communication channels.

关键词： Semantic information Semantic encoding method Context-based decoding method

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Patent-based technological developments and surfactants application of lithium-ion batteries fire-extinguishing agent

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Journal of Energy Chemistry 2024年第1期88卷 39-63,I0002页

作者： Jianqi Zhang Tao Fan Shuai Yuan Chongye Chang kuo Wang Ziwei Song Xinming Qian State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100084China Industrial Safety Research Institute China Academy of Safety Science and TechnologyBeijing 100012China Fire Engineering Department China People’s Police UniversityLangfang 065000HebeiChina

While newer,more efficient Lithium-ion batteries(LIBs)and extinguishing agents have been developed to reduce the occurrence of thermal runaway accidents,there is still a scarcity of research focused on the application of surfactants in different LIBs extinguishing agents,particularly in terms of patented *** aim of this review paper is to provide an overview of the technological progress of LIBs and LIBs extinguishing agents in terms of patents in Korea,Japan,Europe,the United States,China,*** initial part of this review paper is sort out LIBs technology development in different *** addition,to compare LIBs extinguishing agent progress and challenges of liquid,solid,combination of multiple,and *** subsequent section of this review focuses on an in-depth analysis dedicated to the efficiency and challenges faced by the surfactants corresponding design principles of LIBs extinguishing agents,such as nonionic and anionic surfactants.A total of 451,760 LIBs-related patent and 20 LIBs-fire-extinguishing agent-related patent were included in the *** extinguishing effect,cooling performance,and anti-recombustion on different agents have been *** a comprehensive comparison of these agents,this review suggests that temperature-sensitive hydrogel extinguishing agent is ideal for the effective control of LIBs *** progress and challenges of surfactants have been extensively examined,focusing on key factors such as surface activity,thermal stability,foaming properties,environmental friendliness,and electrical ***,it is crucial to emphasize that the selection of a suitable surfactant must align with the extinguishing strategy of the extinguishing agent for optimal firefighting effectiveness.

关键词： LIBs Fire-extinguishing agent Surfactants Patent

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基于变载波频率的永磁同步电机驱动系统效率优化控制

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东南大学学报（自然科学版） 2024年第3期54卷 724-729页

作者：刘凯张阔花为胡铭觐东南大学电气工程学院南京210096

为降低永磁同步电机驱动系统的损耗,提高系统效率,提出了一种基于母线电流反馈的变载波频率优化控制方法.首先,建立了系统损耗数学模型,探究了载波频率与系统损耗的关系.然后,针对离线优化方法对于参数敏感的问题,设计了一种基于母线电... 详细信息

为降低永磁同步电机驱动系统的损耗,提高系统效率,提出了一种基于母线电流反馈的变载波频率优化控制方法.首先,建立了系统损耗数学模型,探究了载波频率与系统损耗的关系.然后,针对离线优化方法对于参数敏感的问题,设计了一种基于母线电流反馈的载波频率在线寻优方法.结果表明,在不同转速与负载条件下均存在使系统损耗最小的最优载波频率,其随转速与负载条件变化而变化.在各个工作点,系统损耗的计算值均与实测值基本吻合.在线寻优方法在中高负载情况下能够实现约0.6%的效率优化,并且在负载变化的情况下仍然能够实现损耗优化.

关键词：变载波频率损耗模型效率优化永磁同步电机

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