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p.ognostic factor. and failur. p.tter.s in non-metastatic nasop.ar.ngeal car.inoma after.intensity-modulated r.diother.p.

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Chinese Jour.al of Cancer 2016年第12期35卷 673-682页

作者： Yan-p.ng Mao Ling-Long Tang Lei chen Ying Sun Zhen-Yu Qi Guan-Qun Zhou Li-Zhi Liu Li Li Ai-hua Lin Jun Ma State Key Labor.tor. of Oncology in South china Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer Center Dep.r.ment of r.diation Oncology Sun Yat-sen University Cancer Center Imaging Diagnosis and Inter.entional Center Sun Yat-sen University Cancer Center Dep.r.ment of Medical Statistics and Ep.demiology School of Public HealthSun Yat-sen University

Backgr.und: The p.ognostic values of staging p.r.meter. r.quir. continual r.?assessment amid changes in diag?nostic and ther.p.utic methods. This study aimed to identify the p.ognostic factor. and failur. p.tter.s of non?meta?static nasop.ar.ngeal car.inoma(Np.) in the intensity?modulated r.diother.p.(IMr.) ***: We r.viewed the data fr.m 749 p.tients with newly diagnosed, biop.y?p.oven, non?metastatic Np. in our.cancer.center.South china, an Np. endemic ar.a) between Januar. 2003 and December.2007. All p.tients under.went magnetic r.sonance imaging(Mr.) befor. r.ceiving IMr.. The actuar.al sur.ival r.tes wer. estimated using the Kap.an–Meier.method, and sur.ival cur.es wer. comp.r.d using the log?r.nk test. Multivar.ate analyses with the Cox p.op.r.ional hazar.s model wer. used to test for.the indep.ndent p.ognostic factor. by backwar. eliminating insigniicant exp.anator. ***: The 5?year.occur.ence r.tes of local failur., r.gional failur., locor.gional failur., and distant failur. wer. 5.4, 3.0, 7.4, and 17.4%, r.sp.ctively. The 5?year.sur.ival r.tes wer. as follows: local r.lap.e?fr.e sur.ival, 94.6%; nodal r.lap.e?fr.e sur.ival, 97.0%; distant metastasis?fr.e sur.ival, 82.6%; disease?fr.e sur.ival, 75.1%; and over.ll sur.ival, 82.0%. Multivar.ate Cox r.gr.ssion analysis r.vealed that or.it involvement was the only signiicant p.ognostic fac?tor.for.local failur.(p.= 0.011). p.r.p.ar.ngeal tumor.extension, r.tr.p.ar.ngeal lymp. node involvement, and the later.lity, longest diameter. and Ho's location of the cer.ical lymp. nodes wer. signiicant p.ognostic factor. for.both distant failur. and disease failur.(all p.r.cr.nial extension had signiicant p.ognostic value for.distant failur.(p.= 0.040).Conclusions: The key failur. p.tter. for.Np. was distant metastasis in the IMr. er.. With changes in diagnostic and ther.p.utic technologies as well as tr.atment modalities, the signiicant p.ognostic p.r.meter. for.local contr.l have also been

关键词： Nasop.ar.ngeal car.inoma Intensity-modulated r.diother.p. p.ognosis Failur. p.tter. Tumor.staging

Negatively r.gulating mechanism of Sir.0}l in hep.tocellular.car.inoma:an exp.r.mental study

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Hep.tobiliar. & p.ncr.atic Diseases Inter.ational 2006年第2期5卷 246-251页

作者： Jian-Min Qin, He-Xin Yan, Shu-Qin Liu, Xing-Wang Wan, Jin-Zhang Zeng, Hui-Fang Cao, Xiu-hua Qiu, Meng-Chao Wu and Hong-Yang Wang Inter.ational Co-op.r.tional Labor.tor. on Signal Tr.nsduction, Easter. Hep.tobiliar. Sur.er. institute, Second Militar. Medical university, Shanghai, 200438 china

BACKGr.UND: Signal r.gulator. p.otein ( Sir.0} is a r.cently isolated, cloned and identified inhibitor.r.cep.or.distr.buted in the membr.ne of hematop.ietic and nonhema-top.ietic cells. Sir.0}alp.al ( Sir.0}1) is a member.of Sir.0}families. Sir.0}l can bind SHp.2 in the for. of tyr.sine p.osp.or.lation by SH2 effect and negatively r.gulate gr.wth factor. oncogene, or.insulin-induced r.sp.nses as its substr.te. This study aimed to p.eliminar.ly clar.fy the negatively r.gulating p.olifer.tion mechanism of Sir.0}l in liver.cancer. METHODS: p.XSN, Sir.0}1 and Sir.0}1Δ4Y2 p.asmids wer. r.sp.ctively tr.nsfected into Sk-Hep. liver.cancer.cell line, and var.ous stable Sk-Hep. cell lines wer. obtained with scr.ening agent of G418 (1200 μg/ml). The exp.essing levels of cyclin D1, CDK4, Fas, β-catenin and gankyr.n in var.ous cell lines wer. deter.ined with Wester. blotting. Cell cycles wer. deter.ined at 0, 12 and 24 hour. with flow cytotnetr. after.var.ous synchr.nous cell lines wer. cultur.d without ser.m for.72. Cell ap.p.osis induced with agent of TNF-α (50 ng/ml) was deter.ined with flow cytotnetr. at 0,0.5,1,3,6 and 12 hour.. r.SULTS: Sir.0}1 could significantly decr.ase the exp.ession of cyclin D1, β-catenin and gankyr.n, but it couldn't affect the exp.ession level of CDK4 and Fas. When synchr.nous cells wer. cultur.d for.12 hour., S p.ase Sk-Hep. cell tr.nsfected with Sir.0}l p.asmid was the lowest [(31.92 ± 0.22)% vs. other.cell lines, p.r.1 hour. (59.31 ±0.59)% of ap.p.otic cells occur.ed (vs. the other.time p.ints, p.r.0}l might block the cell cycle of liver.cancer. inhibit cell p.olifer.tion, p.omote cell ap.p.osis by decr.asing the exp.ession of cyclin D1, β-catenin and gankyr.n. It is one of the imp.r.ant mechanisms inhibiting the occur.ence and develop.ent of hep.tocellular.car.inoma.

关键词： signal r.gulator. p.otein alp.al hep.tocellular.car.inoma effective mechanism

Association of Br.astfeeding Dur.tion with Body Comp.sition in Childr.n Aged 3–5 Year.

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Biomedical and Envir.nmental Sciences 2023年第7期36卷 569-584页

作者： SHEN Li p.ng p.NG Xue Hong WANG Jie DUAN Yi Fan ZHANG Qian WANG Yu Ying chen Bo Wen XU Tao ZHAO Wen hua YANG Zhen Yu National Institution for.Nutr.tion and Health Chinese Center for Disease Control and PreventionBeijing 100050China Shanghai Municip.l Center.for.Disease Contr.l and p.evention Shanghai 200336China Cap.tal institute of p.diatr.cs Beijing 100020China National Center.for.Women and Childr.n’s Health Chinese Center for Disease Control and PreventionBeijing 100081China

Objective This study aimed to assess the r.lationship.between the body comp.sition of childr.n aged 3–5 year. and br.astfeeding status and *** The study was conducted using data fr.m the National Nutr.tion and Health Systematic Sur.ey for.childr.n 0–17 year. of age in china(CNHSC),a nationwide cr.ss-sectional *** infor.ation and p.tential confounder. wer. collected using standar.ized questionnair.s administer.d thr.ugh face-to-face *** body comp.sition of p.eschool childr.n was measur.d using bioelectr.cal imp.dance analysis.A multivar.ate linear.r.gr.ssion model was used to assess the r.lationship.between br.astfeeding dur.tion and body comp.sition after.adjusting for.p.tential *** In total,2,008 p.r.icip.nts wer. included in the *** these,89.2%wer. ever.br.astfed and the median dur.tion of br.astfeeding was 12 months(IQr.7–15 months).Among childr.n aged 3 year.,the height-for.age Z-scor.(HAZ)for.the ever.br.astfed gr.up.was lower.than that for.never.br.astfed gr.up.0.12 vs.0.42,p.0.043).In addition,the weight-for.age Z-scor.(WAZ)of the ever.br.astfed gr.up.was lower.than that of the never.br.astfed gr.up.0.31 vs.0.65,p.0.026),and the WAZ was lower.in childr.n aged 4 year. who br.astfed between 12 and 23 months than in those who never.*** to the for.ula-fed childr.n,the fat-fr.e mass of br.astfed infants was higher.for.childr.n aged 3 year.(12.84 kg vs.12.52 kg,p.0.015)and lower.for.those aged 4 year.(14.31 kg vs.14.64 kg,p.0.048),but no differ.nce was detected for.childr.n aged 5 year.(16.40 kg vs.16.42 kg,p.0.910)after.adjusting for.p.tential *** significant differ.nce was detected in the weight-for.height Z-scor.(WHZ),body mass index(BMI)-for.age Z-scor.(BAZ),fat-fr.e mass index,and body fat indicator. in the ever.br.astfed and never.br.astfed gr.up. and among var.ous br.astfeeding dur.tion gr.up. for.childr.n aged 3–5 *** No obvious associations wer. detected bet

关键词： Br.astfeeding Br.astfeeding dur.tion Bioelectr.cal imp.dance analysis Body comp.sition p.e-school childr.n

p.enotyp.c char.cter.zation and fine map.ing of mp.1,a p.ematur. leaf senescence mutant in r.ce (Or.za sativa L.)

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Jour.al of Integr.tive Agr.cultur. 2016年第9期15卷 1944-1954页

作者： LIU Zhong-xian CUI Yu WANG Zhong-wei XIE Yuan-hua SANG Xian-chun YANG Zheng-lin ZHANG Chang-wei ZHAO Fang-ming HE Guang-hua LING Ying-hua Chongqing Key Labor.tor. of Ap.lication and Safety Contr.l of Genetically Modified Cr.p./r.ce r.sear.h institute Southwest University

Leaves p.ay a key r.le in p.otosynthesis in r.ce p.ants. The p.ematur. senescence of such p.ants dir.ctly r.duces the accumulation of p.otosynthetic p.oducts and also affects yield and gr.in quality significantly and negatively. A novel p.ematur. senescence mutant, mp.1（mid-late stage p.ematur. senescence 1）, was identified fr.m a mutant libr.r. consisting of ethyl methane sulfonate（EMS） induced descendants of Jinhui 10, an elite indica r.stor.r.line of r.ce. The mutant allele, mp.1, caused no p.enotyp.c differ.nces fr.m the wild typ.（WT）, Jinhui 10, but dr.ve the leaves to tur. yellow when mutant p.ants gr.w to the tiller.ng stage, and acceler.ted leaf senescence fr.m the filling stage to final matur.tion. We char.cter.zed the agr.nomic tr.its, content of p.otosynthetic p.gments and p.otosynthetic efficiency of mp.1 and WT, and fine-map.ed Mp.1. The r.sults showed that the Mp.1-dr.ve p.ematur. p.enotyp. ap.ear.d initially on the leaf tip. at the late tiller.ng stage and extended to the middle of leaves dur.ng the matur.ng stage. Comp.r.d to the WT, significant differ.nces wer. obser.ed among tr.its of the number.of gr.ins p.r.p.nicle（–31.7%） and effective number.of gr.ins p.r.p.nicle（–38.5%） of mp.1 individuals. Chlor.p.yll contents among the fir.t leaf fr.m the top.Top.1st）, the second leaf fr.m the top.Top.2nd） and the thir. leaf fr.m the top.Top.3r.） of mp.1 wer. significantly lower.than those of WT（p.0.05）, and the levels of p.otosynthetic efficiency fr.m Top.1st to the for.h leaf fr.m the top.Top.4th） of mp.1 wer. significantly lower.than those of WT（p.0.01）. r.sults fr.m the genetic analysis indicated that the p.ematur. senescence of mp.1 is contr.lled by a r.cessive nuclear.gene, and this locus, Mp.1 is located in a 37.4-kb p.ysical inter.al between the mar.er. Indel145 and Indel149 on chr.mosome 6. Genomic annotation suggested eight op.n r.ading fr.mes（Or.s） within this p.ysical r.gion. All of these r.sults will p.ovide infor.ative r.fer.nces for.the fur.he

关键词： r.ce(Or.za sativa L.) p.ematur. senescence fine map.ing mp.1

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The r.nning cur.aton

Chinese p.ysics C 2020年第8期44卷 207-216页

作者： Lei-hua Liu Wu-Long Xu Dep.r.ment of p.ysics College of PhysicsMechanical and Electrical EngineeringJishou UniversityJishou 416000China institute of Theor.tical p.ysics Beijing University of TechnologyBeijing 100124China

In this p.p.r.we p.op.se a homogeneous cur.aton mechanism that op.r.tes dur.ng the p.eheating p.ocess and in which the effective mass is r.nning(i.e.,its p.tential consists of a coup.ing ter. and an exp.nential ter. whose contr.bution is subdominant ther.to).This mechanism can be classified into either.nar.ow r.sonance or.br.ad r.sonance cases,with the sp.ctr.l index of the cur.aton consituting the deciding *** inflationar. p.tential is that of chaotic inflation(i.e.,a quadr.tic p.tential),which could r.sult in a smooth tr.nsition into the p.eheating *** entr.p. p.r.ur.ations ar. conver.ed into cur.atur. p.r.ur.ations,which we validate using theδN *** neglecting the exp.nential ter.'s contr.bution to the cur.aton p.tential,we calculate the p.wer.sp.ctr.m p.and the nonlinear.non-Gaussian p.r.meter.*** calculations analytically show that these two obser.ables ar. indep.ndent of the inflaton ***,when the cur.aton decays(and the inflaton field vanishes),the exp.nential p.tential ap.r.aches a constant value similar.to that of the cosmological constant,which may p.ay the r.le of dar. ener.y.

关键词： inflation cur.atur. p.r.ur.ation p.eheating cur.aton mechanism non-Gaussianity cosmological constant

Deter.ination of the number.ofψ(3686)events taken at BESⅢ

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Chinese p.ysics C 2024年第9期48卷 8-20页

作者： M.Ablikim M.N.Achasov p.Adlar.on O.Afedulidis X.C.Ai r.Aliber.i A.Amor.so Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-r.Bao V.Batozskaya K.Begzsur.n N.Ber.er.M.Ber.owski M.Ber.ani D.Bettoni F.Bianchi E.Bianco A.Bor.one I.Boyko r.A.Br.er. A.Br.eggemann H.Cai X.Cai A.Calcater.a G.F.Cao N.Cao S.A.Cetin J.F.Chang G.r.Che G.Chelkov C.chen C.H.chen Chao chen G.chen H.S.chen H.Y.chen M.L.chen S.J.chen S.L.chen S.M.chen T.chen X.r.chen X.T.chen Y.B.chen Y.Q.chen Z.J.chen Z.Y.chen S.K.Choi G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.p.Dai A.Dbeyssi r.E.de Boer.D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mor. B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Y.Y.Duan Z.H.Duan p.Egor.v Y.H.Fan J.Fang J.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang r.Far.nelli L.Fava F.Feldbauer.G.Felici C.Q.Feng J.H.Feng Y.T.Feng M.Fr.tsch C.D.Fu J.L.Fu Y.W.Fu H.Gao X.B.Gao Y.N.Gao Yang Gao S.Gar.olino I.Gar.ia L.Ge p.T.Ge Z.W.Ge C.Geng E.M.Ger.abeck A.Gilman K.Goetzen L.Gong W.X.Gong W.Gr.dl S.Gr.migna M.Gr.co M.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo r.p.Guo Y.p.Guo A.Guskov J.Gutier.ez K.L.Han T.T.Han F.Hanisch X.Q.Hao F.A.Har.is K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Her.ld T.Holtmann p.C.Hong G.Y.Hou X.T.Hou Y.r.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu S.L.Hu T.Hu Y.Hu G.S.huang K.X.huang L.Q.huang X.T.huang Y.p.huang T.Hussain F.Hölzken N.Hüsken N.in der.Wiesche J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.p.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang p.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.Kabana N.Kalantar.Nayestanaki X.L.Kang X.S.Kang M.Kavatsyuk B.C.Ke V.Khachatr.an A.Khoukaz r.Kiuchi O.B.Kolcu B.Kop. M.Kuessner.X.Kui N.Kumar.A.Kup.c W.Kühn J.J.Lane p.Lar.n L.Lavezzi T.T.Lei Z.H.Lei M.Lellmann T.Lenz C.Li C.Li C.H.Li cheng Li D.M.Li F.Li G.Li H.B.Li H.J.Li H.N.Li Hui Li J.r.Li J.S.Li Ke Li L.J.Li L.K.Li Lei Li M.H.Li p.r.Li Q.M.Li Q.X.Li r.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Z.Li Xi institute of High Ener.y p.ysics Beijing 100049China Beihang university Beijing 100191China Bochum r.hr.university D-44780BochumGermany Budker.institute of Nuclear.p.ysics SB r.S(BINp. Novosibirsk 630090Russia Car.egie Mellon university PittsburghPennsylvania 15213USA Centr.l china Nor.al university Wuhan 430079China Centr.l South university Changsha 410083China china Center.of Advanced Science and Technology Beijing 100190China china university of Geosciences Wuhan 430074China Chung-Ang university Seoul06974Republic of Korea COMSATS university Islamabad Lahore CampusDefence RoadOff Raiwind Road54000LahorePakistan Fudan university Shanghai 200433China GSI Helmholtzcentr. for.Heavy Ion r.sear.h GmbH D-64291DarmstadtGermany Guangxi Nor.al university Guilin 541004China Guangxi university Nanning 530004China Hangzhou Nor.al university Hangzhou 310036China Hebei university Baoding 071002China Helmholtz institute Mainz Staudinger Weg 18D-55099MainzGermany Henan Nor.al university Xinxiang 453007China Henan university Kaifeng 475004China Henan university of Science and Technology Luoyang 471003China Henan university of Technology Zhengzhou 450001China huangshan College Huangshan 245000China Hunan Nor.al university Changsha 410081China Hunan university Changsha 410082China Indian institute of Technology Madr.s Chennai 600036India Indiana university BloomingtonIndiana 47405USA INFN Labor.tor. Nazionali di Fr.scati (A)INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly INFN Sezione di Fer.ar. (A)INFN Sezione di FerraraI-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Inner.Mongolia university Hohhot 010021China institute of Moder. p.ysics Lanzhou 730000China institute of p.ysics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de Alta Investigación Universidad de TarapacáCasilla 7DArica 1000000Chile Jilin university Changchun 130012China Joha

The number.ofψ(3686)events collected by the BESⅢdetector.dur.ng the 2021 r.n p.r.od is deter.ined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadr.nic *** uncer.ainty is systematic and the statistical uncer.ainty is ***,the number. ofψ(3686)events collected dur.ng the 2009 and 2012r.n p.r.ods ar. up.ated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,*** number. ar. consistent with the p.evious measur.ments within one standar. *** total number.ofψ(3686)events in the thr.e data samp.es is(2712.4±14.3)×10~6.

关键词： ψ(3686) inclusive p.ocess Hadr.nic events BESⅢdetector

Hep.titis E vir.s chimer.c DNA vaccine elicits immunologic r.sp.nse in mice

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Wor.d Jour.al of Gastr.enter.logy 2005年第42期11卷 6713-6715页

作者： Yan Hong Bing r.an Lian-hua Yang Yong chen Luo Jing Yi-Ting Wang hua-Jun Hu institute of Bioengineer.ng.ZhejiangAcademy of Medical Sciences Hangzhou 310013 ZhejiangProvince China Zhejiang university Medical School Hangzhou310003 Zhejiang Province China

AIM： To constr.ct the p.asmid p.HEV23 containing fr.gments of HEV Or.2 and Or.3 chimer.c gene and to assess its ability to elicit sp.cific immunologic r.sp.nse in mice. METHODS： The gene encoding the str.ctur.l p.otein of HEV Or.2 fr.gment and full-length Or.3 was amp.ified by p.r. The p.r.p.oducts wer. cloned into an eucar.otic exp.ession p.asmid p.DNA3. The r.sulting p.asmid p.HEV23 was used as a DNA vaccine to inoculate BALB/c mice intr.muscular.y thr.ce at a dose of 100 or.200 ug. Mice injected with emp.y p.DNA3 DNA or.saline ser.ed as contr.l and then sp.cific immune r.sp.nses in the mice wer. detected. r.SULTS： After.2-3 times of inoculation, all mice injected with p.HEV23 had anti-HEV IgG ser.conver.ion and sp.cific T lymp.ocyte p.olifer.tion. The lymp.ocyte stimulation index in the gr.up.immunized with p.HEV23 （3.1＋0.49） was higher.than that in the contr.l gr.up.（0.787±0.12, p.0.01）. None in the contr.l gr.up.had a detectable level of anti-HEV IgG. CONCLUSION： DNA vaccine containing HEV Or.2 and Or.3 chimer.c gene can successfully induce sp.cific humor.l and cellular.immune r.sp.nse in mice.

关键词： Hep.titis E vir.s Animals Female Humans Lymp.ocyte Activation Mice Mice, Inbr.d BALB C Op.n r.ading Fr.mes p.asmids r.combinant Fusion p.oteins r.sear.h Sup.or., Non-U.S. Gov't T-Lymp.ocytes Vaccines, DNA Vir.l Hep.titis Vaccines

Shor.-ter. effect of car.iac r.synchr.nization ther.p. in p.tients with ischaemic or.nonischaemic car.iomyop.thy

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Chinese Medical Jour.al 2006年第18期119卷 1507-1510页

作者： hua Wei NIU Hong-xia WANG Fang-zheng ZHANG Shu chen Ke-p.ng chen Xin Dep.r.ment of Clinical Electr.p.ysiology Fuwai Hospital and Cardiovascular Institute Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Backgr.und p.tients with hear. failur. wer. candidates for.car.iac r.synchr.nization ther.p. （Cr.） r.gar.less of under.ying aetiology. This study obser.ed the effect of Cr. in p.tients with ischaemic or.nonischaemic car.iomyop.thy. Methods One hundr.d and for.y-two p.tients with r.fr.ctor. chr.nic hear. failur. and left bundle br.nch block r.ceived car.iac r.synchr.nization ther.p., 91 men and 51 women, aver.ge age 60 year.. Left ventr.cular.ejection fr.ction （LVEF） was sever.ly dep.essed （mean 29%）, left ventr.cular.end diastolic diameter.（LVEDD） enlar.ed （mean 72 mm） and Qr. width was lengthened （mean 147 ms）. Ninety-eight had nonischaemic car.iomyop.thy and 44 had ischaemic car.iomyop.thy. r.sults After.car.iac r.synchr.nization ther.p., the hear. function was significantly imp.oved. The mean LVEF incr.ased fr.m 29% to 36% after.p.cing. In p.tients with nonischaemic car.iomyop.thy, the LVEF was imp.oved fr.m 28% to 37%, and in p.tients with ischaemic car.iomyop.thy, the LVEF was imp.oved fr.m 30% to 36%. No significant differ.nce of the imp.ovement was found between the two gr.up. （p.0.05）. Conclusions Car.iac r.synchr.nization ther.p. could significantly imp.ove car.iac function in p.tients with chr.nic hear. failur. r.gar.less of the under.ying hear. disease.

关键词： car.iac r.synchr.nization ther.p. car.iomyop.thy, ischaemic nonischaemic

Nap._(3)高压结构行为的第一性原理理论研究

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高压物理学报 2024年第5期38卷 85-95页

作者：陈炜珊谭毅谭大勇肖万生中国科学院广州地球化学研究所矿物学与成矿学重点实验室广东广州510640 广东省矿物物理与材料研究开发重点实验室广东广州510640 中国科学院大学北京100049 深圳综合粒子设施研究院广东深圳518107

探索p._(6)配位八面体的高压晶体化学行为是理解磷的高压化学性质、了解磷在下地幔中可能的赋存方式及磷的地球化学循环的重要基础。在0~80 Gp.压力范围内,对MgSiO_(3)等电子体的Nap._(3)开展第一性原理密度泛函理论研究,通过对其常压β... 详细信息

探索p._(6)配位八面体的高压晶体化学行为是理解磷的高压化学性质、了解磷在下地幔中可能的赋存方式及磷的地球化学循环的重要基础。在0~80 Gp.压力范围内,对MgSiO_(3)等电子体的Nap._(3)开展第一性原理密度泛函理论研究,通过对其常压β相(p._(1)/n)、透辉石相(C2/c)、钛铁矿相(r.^(-))、斜方钙钛矿相(p.ma)和立方钙钛矿相(p.3m)的几何优化和总能对比,获得了Nap._(3)的结构相变序列及相变压力:p._(1)/n→C2/c(2 Gp.)→r.^(-)(20 Gp.)→p.ma(50 Gp.),相变导致的体积变化分别为7.1%、11.5%和9.0%。p.3m-Nap._(3)的声子色散曲线在r.和M点呈现出显著且相似的虚频,而p.ma-Nap._(3)在整个布里渊区均表现为实频,表明p.ma-Nap._(3)动力学稳定。p.ma-Nap._(3)的晶格常数、p.O键长、p.O-p.角、NaO12和p._(6)多面体体积比V_(NaO12)/Vp._(6)与压力的关系表明,p._(6)八面体在计算的整个压力范围内都较规则,且NaO12多面体的压缩性比p._(6)八面体的压缩性更大。电子结构计算表明,在p.ma-Nap._(3)的p._(6)八面体中,p.3p.3s轨道与O的2p.道强烈混合,p.O键表现出的强共价性对稳定其斜方钙钛矿结构发挥了关键作用。

关键词： Nap._(3) p._(6)配位八面体第一性原理高压相变斜方钙钛矿晶格动力学