检索结果-南通市图书馆

Factors and Their Impact on Treatment Effect of Acupuncture in Different Outcomes:A Meta-Regression of Acupuncture Randomized Controlled Trials

引用

chinese Journal of Integrative Medicine 2024年第3期30卷 260-266页

作者： XIU Wen-cui GANG Wei-juan ZHOU Qi SHI Lan-jun hu Xiang-yu MING Tian-yu LUO Zhen ZHANG yu-qing JING Xiang-hong institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing100700China China Center for Evidence-Based Traditional chinese Medicine China Academy of Chinese Medical SciencesBeijing100700China Department of Health Research Methods Evidenceand ImpactMcMaster UniversityHamiltonOntarioL8S 4L8Canada Center for Evidence-Based Integrative Medicine-Clarity Collaboration Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China

Background:The effects of acupuncture have varied in different randomized controlled trials(RCTs),and there are many factors that influence treatment effect of acupuncture in different outcomes,with conflicting ***:To identify factors and their impact on the treatment effect of acupuncture in different ***:Acupuncture RCTs were searched from 7 databases including Medline(Pub Med),Embase,Cochrane Central Register of Controlled Trials,China National Knowledge Infrastructure,Wanfang Database,VIP Database,and China Biology Medicine disc between January 1st,2015 and December 3.st,*** studies must compare acupuncture to no acupuncture,sham acupuncture,or waiting lists,and report at least 1patient-important outcome.A multi-level meta-regression was conducted using a 3.level robust mixed model and univariate analyses were performed for all independent variables,even those excluded from the multivariable model due to *** used thresholds of 0.2 and 0.4 for the difference of standardized mean differences(SMDs),categorising them as small(0.4) ***:The pain construct analysis involved 211 effect estimates from 153.studies and 14 independent ***-frequency acupuncture treatment sessions produced larger effects compared to low-frequency sessions [large magnitude,the difference of adjusted SMDs 0.46,95% confidence interval(CI) 0.07 to 0.84;P=0.02].The non-pain symptoms construct analysis comprised 3.3.effect estimates from 23. studies and 15 independent *** acupuncture showed moderately larger effects when compared to non-penetrating acupuncture(0.3.,95% CI 0.06 to 0.53.P=0.01).The function construct analysis included 495 effect estimates from 274 studies and 14 independent *** acupuncture and the flexible acupuncture regimen showed moderately larger effects,compared to non-penetrating acupuncture and fixed regimen,respectively(0.40,95% CI 0

关键词： acupuncture randomized controlled trial patient-important outcome meta-regression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reaction Kinetics and Secondary Organic Aerosol Composition Analysis of 2-Cyclohexen-1-one with NO_(3. Radicals

引用

Chemical Research in chinese Universities 2024年第4期40卷 730-736页

作者： hu Lin TONG Shengrui XU Yanyong ZHANG Hailiang yu Shanshan CHEN Meifang GE Maofa Structural Chemistry of Unstable and Stable Species Chinese Academy of Sciences Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing100190P.R.China College of Ecology and Environment Xinjiang UniversityUrumqi830017P.R.China University of chinese academy of sciences Beijing100049P.R.China

Unsaturated ketones are typical oxygenated volatile organic compounds(OVOCs)with high reactivity,and are important precursors in air *** sources of OVOCs are complex and include direct emissions and secondary oxidation formation of VOCs in the atmosphere.2-Cyclohexen-1-one is a widespread substance,and is derived from the industrial catalytic oxidation of *** this paper,we investigated the rate constants of the chemical reactions of 2-cyclohexen-1-one with NO_(3. radicals,which is(7.25±0.29)×10^(-15) cm^(3.·molecule^(-1)·s^(-1) at 298 K and under 1 atm(1 atm=1013.5Pa).It supplemented the kinetics of NO_(3. radicals database,and revealed its effects in the nighttime *** addition,the reaction products of 2-cyclohexen-1-one with NO_(3. radicals were detected by Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR MS),which revealed a series of nitrate esters in the composition of the secondary organic aerosol(SOA),which may reduce atmospheric ***,the possible pathways for the generation of the products were developed.

关键词： Kinetics Unsaturated ketone Nitrate radical Secondary organic aerosol

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Local Scour Mechanisms and Prediction Methods Around Offshore Wind Turbine Foundations:Insights and Future Directions

引用

Journal of Ocean University of China 2024年第5期23卷 1248-1262页

作者： YANG Qi hu Ruigeng yu Peng ZHANG Peng XU Zhongqian XU Mengzhen State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China Sinopec Petroleum Engineering Corporation Dongying 257100China Key Laboratory of Geological Safety of Coastal Urban Underground Space Ministry of Natural ResourcesQingdao Geo-Engineering Surveying InstituteQingdao 266101China Qingdao Qingzi Engineering Consulting Co. Ltd.Qingdao 266061China Qingdao Water Affairs Development Service Center Qingdao 266033China

Local scour around offshore wind turbine foundations presents a considerable challenge due to its potential influence on structural stability,driven by hydrodynamic *** research has made strides in comprehending scouring mechanisms,notable complexities persist,specifically with newer foundation *** these limitations is vital for advancing our understanding of scour mechanisms and for improving mitigation strategies in offshore wind energy *** review synthesizes current findings on local scour across various offshore foundations,encompassing field observations,data-driven approaches,turbulence-sediment interactions,scour evolution processes,influencing factors,and numerical model *** objective is to enrich our understanding of local scour *** addition,future research directions are outlined,including the development of robust arti-ficial intelligence models for accurate predictions,the exploration of vortex structure characteristics,and the refinement of numerical models to strengthen prediction capabilities while minimizing computational efforts.

关键词： local scour offshore wind turbine foundations wave-current actions sediment transport multiscale vortices numerical modeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Recent advances in the application of MXenes for neural tissue engineering and regeneration

引用

Neural Regeneration Research 2024年第2期19卷 258-263页

作者： Menghui Liao Qingyue Cui Yangnan hu Jiayue Xing Danqi Wu Shasha Zheng yu Zhao Yafeng yu Jingwu Sun Renjie Chai State Key Laboratory of Digital Medical Engineering Department of Otolaryngology Head and Neck SurgeryZhongda HospitalSchool of Life Sciences and TechnologyAdvanced Institute for Life and HealthJiangsu Province High-Tech Key Laboratory for Bio-Medical ResearchSoutheast UniversityNanjingJiangsu ProvinceChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Oto-Rhino-Laryngology West China HospitalSichuan UniversityChengduSichuan ProvinceChina First Affiliated Hospital of Soochow University SuzhouJiangsu ProvinceChina Department of Otolaryngology-Head and Neck Surgery The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Otolaryngology Head and Neck Surgery Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina beijing Key Laboratory of Neural Regeneration and Repair Capital Medical UniversityBeijingChina

Transition metal carbides and nitrides(MXenes)are crystal nanomaterials with a number of surface functional groups such as fluorine,hydroxyl,and oxygen,which can be used as carriers for proteins and *** have excellent biocompatibility,electrical conductivity,surface hydrophilicity,mechanical properties and easy surface ***,at present,the stability of most MXenes needs to be improved,and more synthesis methods need to be *** are good substrates for nerve cell regeneration and nerve reconstruction,which have broad application prospects in the repair of nervous system *** the application of MXenes in neuroscience,mainly at the cellular level,the long-term in vivo biosafety and effects also need to be further *** review focuses on the progress of using MXenes in nerve regeneration over the last few years;discussing preparation of MXenes and their biocompatibility with different cells as well as the regulation by MXenes of nerve cell regeneration in two-dimensional and three-dimensional environments in *** have great potential in regulating the proliferation,differentiation,and maturation of nerve cells and in promoting regeneration and recovery after nerve *** addition,this review also presents the main challenges during optimization processes,such as the preparation of stable MXenes and long-term in vivo biosafety,and further discusses future directions in neural tissue engineering.

关键词： hydrogels MXenes nerve regeneration neural cells neural stem cells organoids spiral ganglion neurons

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Beyond clinical trials:CDK4/6 inhibitor efficacy predictors and nomogram model from real‐world evidence in metastatic breast cancer

引用

Cancer Innovation 2024年第6期3卷 58-75页

作者： Binliang Liu Zhe‐yu hu Ning Xie Liping Liu Jing Li xiaohong Yang huawu xiao Xuran Zhao Can Tian hui Wu Jun Lu Jianxiang Gao Xuming hu Min Cao Zhengrong Shui yu Tang Quchang Ouyang Department of Breast Cancer Medical Oncology Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangshaHunanChina Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Gastroenterology The Third Xiangya Hospital of Central South UniversityChangshaHunanChina

Background:CDK4/6 inhibitors(CDK4/6i)have shown promising results in the treatment of hormone receptor‐positive(HR+)metastatic breast cancer(MBC)when combined with endocrine therapy(ET).It is crucial to evaluate the actual effectiveness and safety of CDK4/6i in clinical practice,as well as to analyze the factors that can predict their ***:Patients with HR+MBC who received CDK4/6i‐based therapy between May 2016 and May 2023.at hunan Cancer Hospital were evaluated for progression‐free survival(PFS).Adverse reactions were assessed based on the National Cancer institute Common Toxicity Criteria(version 5.0).Results:This study included 3.4 patients,with a median PFS(mPFS)of 12.8 months(range:10.4–15.2 months).After adjustment,Cox multivariate regression analysis revealed that visceral metastasis(specifically liver and brain metastases),Eastern Cooperative Oncology Group Performance Status(ECOG PS)≥1,estrogen receptor≤80%,progesterone receptor≤10%,Ki‐67>3.%,and treatment in later stages were significant factors associated with reduced *** on this,we created a prognostic nomogram and validated its performance,obtaining a C‐index of 0.714(95%confidence interval:0.640–0.787)as well as reliable calibration and clinical *** mPFS of CDK4/6i rechallenge was 7.7 months;for patients who initially discontinued CDK4/6i for reasons other than disease progression,CDK4/6i rechallenge still provided a mPFS of 11.4 *** tolerability and safety of combining CDK4/6is with ET were *** events led to treatment discontinuation in 3.8%of ***(29.1%),leukopenia(13.7%),and anemia(4.1%)were the primary grade 3.4 adverse ***:This real‐world study highlights the ample efficacy and reasonable safety of combined CDK4/6i and ET in patients with HR+*** treatment decisions and ongoing safety monitoring are important to optimize the therapeutic benefit of CDK4/6i treatment.

关键词： breast cancer CDK4/6 inhibitor efficacy predictive factors real‐word study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of self-similar stresses on scenario earthquake construction:An example along the Tanlu Fault

引用

Science China Earth sciences 2024年第5期67卷 1687-1697页

作者： Feng hu huajian YAO Houyun yu Zeyu LU Jieyi HOU Song LUO Zhigang SHAO xiaofei CHEN School of Earth and Space sciences University of Science and Technology of ChinaHefei 230026China Mengcheng Geophysical National Field Scientific Observatory Hefei 230026China Department of Earth and Space Science Southern University of Science and TechnologyShenzhen 518055China institute of Earthquake Prediction China Earthquake AdministrationBeijing 100036China

As a famous deep and large fault in eastern China,the Tanlu Fault passes through Anhui,Jiangsu,and Shandong and into northeastern *** is important to improve the understanding of seismic hazard assessments in areas near *** start a scenario earthquake simulation in the M7.5 earthquake potential area of the Xinyi-Sihong segment of the Tanlu *** fault rupture length and width are constrained according to the scaling law of large intraplate earthquakes,the background normal stress is depth dependent,and the initial shear stresses are determined using trial and error by matching the earthquake *** the 120 km rupture length of the M7.5 earthquake,we compare the horizontal uniform stress model and self-similar stress perturbation *** findings reveal that the seismic source time function of the horizontal uniform stress model is similar to that of the Haskell model and that of the self-similar stress perturbation model is more similar to that of a real earthquake *** compare the dynamic rupture simulation and ground motion results under four different stress conditions and find that the shorter the characteristic length of the self-similar function is,the rougher the initial *** the M7.5earthquake with an epicenter in the vicinity of Suqian,the Xinyi-Tancheng segment,which is located in the IX-intensity zone north of the epicenter,vibrates more strongly on the northern side than on the southern side due to the influence of the lowvelocity zone and the peak slip *** response spectra analysis at stations in the study area is useful for improving the earthquake resistance capability.

关键词： Scenario earthquakes Self-similar stress Tanlu Fault Dynamic rupture Ground motion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development

引用

Cell Research 2004年第1期14卷 8-15页

作者： yu Xin hu~*, Yong Hong WANG~*, Xin Fang LIU, Jia Yang LI~(**) institute of Genetics and Developmental Biology,{3., beijing 100101, China. Li JY Chinese Acad Sci Inst Genet & Dev Biol Beijing 100101 Peoples R China

RAV1 is a novel DNA-binding protein with two distinct DNA-binding domains unique in higher plants, but its role in plant growth and development remains unknown. Using cDNA array, we found that transcription of RAV1 is downregulated by epibrassinolide (epiBL) in Arabidopsis suspension cells. RNA gel blot analysis revealed that epiBL-regulated RAV1 transcription involves neither protein phosphorylation/dephosphorylation nor newly synthesized protein, and does not require the functional BRI1, suggesting that this regulation might be through a new BR signaling pathway. Overexpressing RAV1 in Arabidopsis results in a retardation of lateral root and rosette leaf development, and the underexpression causes an earlier flowering phenotype, implying that RAV1 may function as a negative regulatory component of growth and development.

关键词： RAV1 Brassinosteroid signal transduction Arabidopsis thaliana.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Metal-Free,Site-Selective C-H Fluorination of Heteroarenes Under Visible Light

引用

CCS Chemistry 2024年第7期6卷 1681-1688页

作者： Cheng huang Chang-Ming You yu-Shu Qin Rui-Nan Ci Peng {3. Sheng Tang Bin Liu Zhenhong Wei Li-Zhu Wu hu Cai School of Chemistry and Chemical Engineering Nanchang UniversityNanchangJiangxi 330031 Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and ChemistryUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100190 School of Future Technology University of Chinese Academy of SciencesBeijing 100049

The site-selective C-H fluorination of heteroarenes is a straightforward approach to accessing valuable heteroaryl fluorides but remains a formidable ***,we report a general strategy for visible-light-induced C-H fluorination of heteroarenes via the merger of N-F fluorinating reagents and *** paramagnetic resonance experiments provide evidence for the homolytic cleavage of the N-F bond under blue light-emitting diode irradiation,which is the key step in the *** transformation is metal-free,photocatalysts-free,and site-selective under mild reaction conditions(ambient temperature,visible-light irradiation,tolerant to H2O).The robustness of this protocol has also been highlighted by late-stage modification of complex and medicinally relevant molecules.

关键词： selective C-H fluorination heteroaryl fluorides C(sp^(2))-F bond formation photochemistry radical chemistry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transfer force perception skills to robot‐assisted laminectomy via imitation learning from human demonstrations

引用

CAAI Transactions on Intelligence Technology 2024年第4期9卷 903-916页

作者： Meng Li xiaozhi Qi xiaoguang Han Ying hu Bing Li {3. Zhao Jianwei Zhang Harbin institute of Technology ShenzhenChina Shenzhen institute of Advanced Technology Chinese Academy of SciencesShenzhenChina Shenzhen Key Laboratory of Minimally Invasive Surgical Robotics and System Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenChina beijing Jishuitan Hospital Capital Medical UniversityBeijingChina Department of Orthopedics Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina University of Hamburg Hamburg22527Germany

A comparative study of two force perception skill learning approaches for robot‐assisted spinal surgery,the impedance model method and the imitation learning(IL)method,is *** impedance model method develops separate models for the surgeon and patient,incorporating spring‐damper and bone‐grinding *** surgeons'feature parameters are collected and mapped using support vector regression and image navi-gation *** imitation learning approach utilises long short‐term memory networks(LSTM)and addresses accurate data labelling challenges with custom *** results demonstrate skill recognition rates of 63.61%-74.62%for the impedance model approach,relying on manual feature ***,the imitation learning approach achieves a force perception recognition rate of 91.06%,outperforming the impedance model on curved bone *** findings demonstrate the potential of imitation learning to enhance skill acquisition in robot‐assisted spinal surgery by eliminating the laborious process of manual feature extraction.

关键词： learning(artificial intelligence) medical applications medical signal processing robotics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nanodiamond:a promising metal-free nanoscale material in photocatalysis and electrocatalysis

引用

Rare Metals 2024年第8期43卷 3501-3552页

作者： xiao-Wu Gao Zi-Wei Zhao Yang He Sai-Fei Fan Ke-Ran Jiao Si-yu Lou Xin-yue Han Peng-Fei Song Rong Cai Z{3.n {3. Zhong-Jie Jiang Yong-Jie Wang Jia-Qi Z{3. Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic Systems School of ScienceHarbin Institute of TechnologyShenzhen 518055China National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of TechnologyHarbin 150080China School of Advanced Technology Xi'an Jiaotong-Liverpool UniversitySuzhou215000China Department of Biosciences Rice UniversityHoustonTX 77251USA institute of Industrial Catalysis School of Chemical Engineering and TechnologyXi'an Jiaotong UniversityXi'an 710049China Guangzhou Key Laboratory for Surface Chemistry of Energy Materials New Energy Research Institute&Guangdong Engineering and Technology Research Center for Surface Chemistry of Energy MaterialsCollege of Environment and EnergySouth China University of TechnologyGuangzhou 510006China

Benefiting from its surface-rich functional groups,eco-friendliness,impressive electrochemical properties,excellent light absorption,structural tunability at the atomic/morphological level,and ultra-high stability under harsh conditions,nanodiamond has emerged as a promising carbon-based non-metallic material in the field of energy conversion such as electrocatalysis and ***,nanodiamond,as a new generation of green catalysts,can overcome the poisoning of catalysts by complex pollutants in advanced oxidation processes,thus effectively removing organic matter from water,which is unparalleled in reducing the cost of water purification and avoiding secondary cross-contamination of water by traditional heavy metal-based ***,we review the research and development of nanodiamonds as major electrocatalysts and photocatalysts for energy conversion and for air/water treatment for environmental *** relevant properties,trimming strategy,mechanistic understanding,and design principles of nanodiamond as a catalyst are described,as well as the challenges and prospects of this emerging field.

关键词： Carbon materials Nanodiamond Electrocatalysis Photocatalysis Energy conversion Pollutant treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：