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Molecular Typing of Brucella Suis Collected from 1960s to 2010s in China by MLVA and PFGE

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Biomedical and Environmental Sciences 2013年第6期26卷 504-508页

作者： LI Zhen Jun CUI Bu Yun CHEN Hai CHEN Jing Diao ZHAO Hong Yan piao Dong ri JIANG Hai ZHANG Li TANG Xu KE Chang Wen YAO zhen TIAN Guo Zhong State Key Laboratory for Communicable Disease Prevention and Control National Institute for Communicable Disease Control and Prevention Hainan Provincial People's Hospital Guangdong Provincial Center for Disease Control and Prevention

Brucellosis is a bacterial anthropozoonosis usually caused by Brucella abortus, Brucella melitensis, Brucella suis and Brucella canis. Brucella suis, the causative agent of swine brucellosis, is classified into five biovars and preferentially infects different animal hostsIll. In China, brucellosis is a national notifiable communicable disease both in animals and in human. In 2009, 35 816 brucellosis cases were reported. The annual incidence was 2.7 per 100 000 population.

关键词： MLVA Molecular Typing of Brucella Suis Collected from 1960s to 2010s in China by MLVA and PFGE 2010

Comparing Arsenic-Containing Qinghuang Powder and Low-Intensity Chemotherapy in Elderly Patients with Acute Myeloid Leukemia

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Chinese Journal of Integrative Medicine 2023年第9期29卷 832-837页

作者： WU Yu-he XIAO Hai-yan QUAN ri-cheng TANG Xu-dong LIU Wei-yi LYU Yan CHEN Zhuo LIU Chi hu Xiao-mei Department of Hematology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China Graduate School China Academy of Chinese Medical SciencesBeijing100700China

Objective To compare the clinical effect of arsenic-containing Qinghuang Powder(QHP)and low-intensity chemotherapy(LIC)in treatment of elderly acute myeloid leukemia(eAML)*** Clinical data of 80 eAML patients treated at Xiyuan Hospital of China Academy of Chinese Medical Sciences from January 2015 to December 2020 were retrospectively *** treatment scheme was designed by real world study according to patients’preference,and patients were divided into a QHP group(35 cases)and a LIC group(45 cases).The median overall survival(mOS),1-,2-,and 3-year OS rates,and incidence of adverse events were compared between the two *** The mOS of 80 patients was 11 months,and the 1-,2-,and 3-year OS rates were 45.51%,17.96%,and 11.05%,*** QHP and LIC groups demonstrated no significant difference in mOS(12 months vs.10 months),1-(48.57%vs.39.65%),2-(11.43%vs.20.04%),and 3-year OS rates(5.71%vs.13.27%,all P>0.05).Moreover,the related factors of mOS demonstrated no significant difference in patients with age>75 years(11 months vs.8 months),secondary AML(11 months vs.8 months),poor genetic prognosis(9 months vs.7 months),Eastern Cooperative Oncology Group performance status score≥(10 months vs.7 months)and hematopoietic stem cell transplant comorbidity index≥4(11 months vs.7 months)between the QHP and LIC groups(all P>0.05).However,the incidence of myelosuppression was significantly lower in the QHP group than that in the LIC group(28.57%vs.73.33%,P<0.01).Conclusions QHP and LIC had similar survival rates in eAML patients,but QHP had a lower myelosuppression ***,QHP can be an alternative for eAML patients who do not tolerate LIC.

关键词： acute myeloid leukemia elderly Qinghuang Powder low-intensity chemotherapy Chinese medicine

Recent Advances in Understanding Multi-scale Climate Variability of the Asian Monsoon

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Advances in Atmospheric Sciences 2023年第8期40卷 1429-1456页

作者： Wen CHEN Renhe ZHANG Renguang WU Zhiping WEN Liantong ZHOU Lin WANG Peng hu Tianjiao MA Jinling piao Lei SONG Zhibiao WANG Juncong LI Hainan GONG Jingliang huANGFU Yong LIU Department of Atmospheric Sciences Yunnan UniversityKunming 650500China Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Department of Atmospheric and Oceanic Sciences Fudan UniversityShanghai 200438China Department of Atmospheric Sciences School of Earth SciencesZhejiang UniversityHangzhou 310058China

Studies of the multi-scale climate variability of the Asian monsoon are essential to an advanced understanding of the physical processes of the global climate *** this paper,the progress achieved in this field is systematically reviewed,with a focus on the past several *** achievements are summarized into the following topics:(1)the onset of the South China Sea summer monsoon;(2)the East Asian summer monsoon;(3)the East Asian winter monsoon;and(4)the Indian summer ***,new results are highlighted,including the advanced or delayed local monsoon onset tending to be synchronized over the Arabian Sea,Bay of Bengal,Indochina Peninsula,and South China Sea;the basic features of the record-breaking mei-yu in 2020,which have been extensively investigated with an emphasis on the role of multi-scale processes;the recovery of the East Asian winter monsoon intensity after the early 2000s in the presence of continuing greenhouse gas emissions,which is believed to have been dominated by internal climate variability(mostly the Arctic Oscillation);and the accelerated warming over South Asia,which exceeded the tropical Indian Ocean warming,is considered to be the main driver of the Indian summer monsoon rainfall recovery since 1999.A brief summary is provided in the final section along with some further discussion on future research directions regarding our understanding of the Asian monsoon variability.

关键词： Asian monsoon multi-scale climate variability monsoon onset East Asian summer monsoon East Asian winter monsoon Indian summer monsoon

Adaptive output feedback formation tracking for a class of multiagent systems with quantized input signals

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Frontiers of Information Technology & Electronic Engineering 2018年第9期19卷 1086-1097页

作者： Jing-lin hu Xiu-xia SUN Lei HE ri LIU Xiong-feng DENG Equipment Management and UAV Engineering College Air Force Engineering Universit

A novel adaptive output feedback control approach is presented for formation tracking of a multiagent system with uncertainties and quantized input signals. The agents are described by nonlinear dynamics models with unknown parameters and immeasurable states. A high-gain dynamic state observer is established to estimate the immeasurable states. With a proper design parameter choice, an adaptive output feedback control method is developed employing a hysteretic quantizer and the designed dynamic state observer. Stability analysis shows that the control strategy can guarantee that the agents can maintain the formation shape while tracking the reference trajectory. In addition, all the signals in the closed-loop system are bounded. The effectiveness of the control strategy is validated by simulation.

关键词： Multiagent system Adaptive output feedback Formation tracking Hysteretic quantizer

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长白山旅游纪念品的开发策略研究

艺术百家 2010年第S2期26卷 172-175页

作者：朴成日延边大学美术学院

目前,影响和制约长白山旅游纪念品市场健康发展的主要因素是,产品质量差、档次低、品种单一、产品定位不清、无特色等。长白山旅游业只有不断地挖掘和利用旅游纪念品的价值,抓住地域特点、民俗特色、追求创新、注重质量、改善经营思路,... 详细信息

目前,影响和制约长白山旅游纪念品市场健康发展的主要因素是,产品质量差、档次低、品种单一、产品定位不清、无特色等。长白山旅游业只有不断地挖掘和利用旅游纪念品的价值,抓住地域特点、民俗特色、追求创新、注重质量、改善经营思路,其开发才能尽快走出低谷,开辟新的具有长白山地域特色的旅游纪念品市场,使长白山旅游业造成商旅一体化发展模式,才能有利于长白山旅游资源的保护和长白山旅游经济的可持续发展。

关键词：长白山旅游纪念品艺术设计地域特色开发

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航渡中反潜直升机的配置

舰船科学技术 2012年第3期34卷 118-121页

作者：朴成日海军大连舰艇学院作战与训练系辽宁大连116018

水面舰艇编队航渡时,针对潜艇威胁,通常利用反潜直升机隐蔽、迅速的优势,将其配置在某一区域实施警戒,以达到对潜防御的目的。本文基于潜艇的威胁方向,分别对编队前方、侧翼以及综合前方和侧翼,探讨了反潜直升机警戒线的配置方法。在确... 详细信息

水面舰艇编队航渡时,针对潜艇威胁,通常利用反潜直升机隐蔽、迅速的优势,将其配置在某一区域实施警戒,以达到对潜防御的目的。本文基于潜艇的威胁方向,分别对编队前方、侧翼以及综合前方和侧翼,探讨了反潜直升机警戒线的配置方法。在确定反潜直升机使用吊放声呐搜索方法的基础上,采用自同步思想,对反潜直升机警戒线的配置参数给出了定量描述。得出的结论实用、可行,为制定对潜防御方案提供了参考依据。

关键词：配置反潜直升机对潜防御

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我国图们江地区开发开放的战略思考

经济纵横 2007年第7期 47-49页

作者：朴日勋中共吉林省委讲师团吉林长春130033

图们江地区国际合作开发已进入稳步发展时期。为早日实现图们江地区"东北亚物流中心"这一目标,需要采取相应的的对策。

关键词：图们江地区国际开发现状对策

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综合作战区中双航母编队区域防空舰阵位配置

计算机仿真 2017年第4期34卷 17-20+124页

作者：朴成日海军大连舰艇学院舰船指挥系

双航母编队在综合作战区执行作战任务时,通常运用防空舰前出一定距离执行区域防空任务,区域防空舰阵位配置理论研究对提高编队防空能力具有重要的军事意义。研究区域防空舰阵位配置问题,难点在于明确区域防空舰阵位配置的影响因素及约... 详细信息

双航母编队在综合作战区执行作战任务时,通常运用防空舰前出一定距离执行区域防空任务,区域防空舰阵位配置理论研究对提高编队防空能力具有重要的军事意义。研究区域防空舰阵位配置问题,难点在于明确区域防空舰阵位配置的影响因素及约束条件,这也是建立区域防空舰阵位配置模型的关键依据。基于区域防空舰作战任务,提出了阵位配置的约束条件,针对前出距离、防空纵深、防空扇面角度、巡逻线长度、数量需求等影响因素,运用解析法建立了区域防空舰阵位配置模型,并通过设定合理参数,进行仿真分析验证模型。区域防空舰阵位配置实质上是在各影响因素之间进行平衡,所构建模型为区域防空舰阵位配置提供了理论依据。

关键词：配置区域防空双航母编队综合作战区

7-苄氨基-9,10-二氢-1,2,4-三氮唑并[4,3-a]喹啉衍生物的合成及环合反应的探讨

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化学试剂 2005年第2期27卷 95-96,114页

作者：赵立明朴虎日全哲山延边大学药学院吉林延吉133000

以 6 -氨基 - 3,4- 二氢 - 2 (1H) - 喹啉酮为起始原料 ,经缩合、还原、硫代、环合等反应合成了 5个 7 -苄氨基 - 9,10- 二氢- 1,2 ,4- 三氮唑并 [4 ,3- a]喹啉衍生物。产物的结构经核磁共振谱和质谱确证。

关键词：三氮唑并[4,3-a]喹啉合成环合反应