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Journal of Computational Mathematics 1999年第5期17卷 545-552页

作者： Wei, YM hu, qh Chinese Acad Sci Inst Policy & Management Beijing 100080 Peoples R China Wuhan Inst Chem Technol Wuhan 430073 Peoples R China

The branch-and-bound method with the revised dual simplex for bounded variables is very effective in solving relatively large-size integer linear programming problems. This paper, based on the general forms of the penalties by Beale and Small and the stronger penalties by Tomlin, describes the modifications of these penalties used for the method of bounded variables. The same examples from Petersen are taken and the satisfactory results are shown in comparison with those obtained by Tomlin.

关键词： penalties stronger penalties the revised dual simplex method for bounded variables

碱性成纤维细胞生长因子在人体脂肪移植中的应用

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中国组织工程研究与临床康复 2007年第29期11卷 5665-5667页

作者：易阳艳胡琼华林涛习娅琦万磊南昌大学第二附属医院整形美容科江西省南昌市330006

目的:碱性成纤维细胞生长因子可促进再血管化过程,有利于脂肪细胞的成活。观察碱性成纤维细胞生长因子在自体脂肪移植治疗面部凹陷畸形中的作用效果。方法:选择2001-11/2006-03于南昌大学第二附属医院整形美容科采用自体脂肪移植治疗面... 详细信息

目的:碱性成纤维细胞生长因子可促进再血管化过程,有利于脂肪细胞的成活。观察碱性成纤维细胞生长因子在自体脂肪移植治疗面部凹陷畸形中的作用效果。方法:选择2001-11/2006-03于南昌大学第二附属医院整形美容科采用自体脂肪移植治疗面部凹陷畸形的患者60例,共73个部位,所有患者均排除器质性病变且知情同意。按随机数字表法分为2组,每组30例。取出的脂肪经过清洗、过滤备用。①碱性成纤维细胞生长因子组在要移植的脂肪中加入10μg/L的碱性成纤维细胞生长因子和庆大霉素液,每100mL脂肪颗粒中加入庆大霉素8万单位及碱性成纤维细胞生长因子2万单位。②对照组只加入庆大霉素液不加碱性成纤维细胞生长因子。术后半年随访,观察一次注射后的治疗效果。评估标准:凹陷充填后丰满平坦,双侧对称满意者为优;凹陷充填后较丰满平坦,双侧基本对称较满意者为良。结果:①术后半年随访,本组60例患者均使凹陷部位得到不同改善,无一例发生感染、液化及干酪样坏死等并发症。②术后半年碱性成纤维细胞生长因子组优良率为87%,对照组优良率为57%,两组相比差异具有显著性意义(P<0.05)。结论:碱性成纤维细胞生长因子可以促进人体移植脂肪的存活,改善面部凹陷畸形脂肪移植的术后效果。

关键词：脂肪组织移植成纤维细胞生长因子碱性组织移植

增强型绿色荧光蛋白标记技术示踪组织工程化骨形成

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中国组织工程研究与临床康复 2007年第23期11卷 4496-4499页

作者：戴江华胡琼华戴闽尹东戴育成张吉翔南昌大学第二附属医院整形外科江西省南昌市330006

目的:观察以脂质体介导法转染的增强型绿色荧光蛋白质粒作为骨组织工程种子细胞示踪剂的可行性。方法:实验于2005-07/2006-11在南昌大学第二附属医院分子医学实验室完成。选取12个月龄中国青山羊2只作为骨髓基质干细胞供体。另取BACB/u... 详细信息

目的:观察以脂质体介导法转染的增强型绿色荧光蛋白质粒作为骨组织工程种子细胞示踪剂的可行性。方法:实验于2005-07/2006-11在南昌大学第二附属医院分子医学实验室完成。选取12个月龄中国青山羊2只作为骨髓基质干细胞供体。另取BACB/un裸鼠9只作为骨髓基质干细胞-珊瑚复合物受体。①将已转化pEGFP-N2大肠杆菌109菌种,进行质粒提取并经AvaⅡ酶切鉴定。②脂质体lipofectamine2000介导转染羊骨髓基质干细胞。分别于转染24h、6个月后计算荧光的转染效率。标记与未标记细胞经成骨诱导分化后,检测碱性磷酸酶活性和四环素钙结节染色,以未标记的同期细胞作对照。③将标记细胞接种于珊瑚支架,形成骨髓基质干细胞-珊瑚复合物,分别于体外培养4,7,14d后进行电镜扫描观察。④将体外培养7d的骨髓基质干细胞-珊瑚复合物移植于裸鼠皮下,8周后取出,荧光显微镜下进行示踪观察,苏木精-伊红染色观察组织结构。以未标记的骨髓基质干细胞-珊瑚复合物、单纯珊瑚作对照。结果:共纳入中国青山羊2只,BACB/un裸鼠9只,作为受体的9只裸鼠进入结果分析。①质粒经酶切后电泳,可见3条带,分别为445bp,1938bp,2354bp,确定所提质粒为pEGFP-N2。②转染24h后绿色荧光表达率35%;经G418筛选,转染6个月后绿色荧光表达率75%;与对照组相比,标记细胞碱性磷酸酶活性差异无统计学意义(P>0.05),均具有钙结节形成能力。③标记细胞与材料贴附生长良好,并分泌胶原纤维及钙盐结晶样基质。④组织学示新生骨样组织围绕材料孔隙生成;新生组织细胞内有绿色荧光表达,同时对照组未观察到绿色荧光。结论:脂质体介导法转染的pEGFP-N2标记骨髓基质干细胞,可用于裸鼠体内示踪,是一种理想的组织工程化骨组织的示踪方法。

关键词：组织工程化骨增强型绿色荧光蛋白质粒脂质体珊瑚组织构建

Wave-Current Propagation over a Frictional Topography

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China Ocean Engineering 1998年第4期13卷 417-426页

作者： Zuo, qh Ding, BC Nanjing Hydraul Res Inst River & Harbour Dept Nanjing 210024 Peoples R China

In this paper the parabolic approximation model based on mild-slope equation is used to study wave propagation over a slowly varying and frictional topography under wave-current interaction. A governing equation considering the friction effects is derived by the authors for the first time. A simplified form for the rate of wave energy dissipation is presented on the basis of the wave-current action conservation equation and the bottom friction model given by Yoo and O'connor (1987). Examples reveal that the present computational method can be used for the calculation of wave elements for actual engineering projects with large water areas.

关键词： wave-current frictional topography refraction-diffraction

Crystal Structure of 5 ( l Menthyloxy) 3 Chloro 4 Pyrrolidinyl 2(5H) Furanone

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Chinese Journal of Structural Chemistry 1999年第2期18卷 35-38页

作者： Geng, Z Chen, qh Capital Normal Univ Dept Chem Beijing 100037 Peoples R China Beijing Normal Univ Dept Chem Beijing 100875 Peoples R China

The molecular structure of the title compound 5 ( l menthyloxy) 3 chloro 4 pyrrolidinyl 2(5H) furanone, C 18 H 28 ClNO 3(Ⅰ), has been determined by X ray diffraction at 296(1)K. The crystal is monoclinic with space group P2 1, a=9 457(3), b=10.413(3), c=9.525(2) , β=95.19(2)°, V=934(1)  3, Z=2, M r=341.88, D x =1.22 g/cm 3, μ =2.15 cm -1 , F(000)=368. The final R factor is 0 059, and R w is 0.065 for 1020 observed reflections with I≥3σ(I) . The absolute configuration at C(14) of the acetal carbon was proved to be S , taking into account the known configuration of 1R, 2S, 5R menthyl moiety. There are three rings in the molecule of this compound: the furanone ring, the pyrrolidine ring and the mentholoxy group ring. The franone ring is connected with the pyrrolidine ring and the mentholoxy ring by N atom and μ 2 O bridge atom respectively.

关键词： crystal structure absolute configuration Michael addition elimination reaction

ANALYSIS ON SMALL SCALE BRIDGING IN FIBROUS MONOLITHIC CERAMICS

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Acta Mechanica Solida Sinica 1999年第3期12卷 227-238页

作者： Wu, ZJ Cai, qh Tsing hua Univ Dept Mech Engn Beijing 100084 Peoples R China

Based on shear lag model of interface between fiber and matrix, a new formula that relates the crack opening displacement and bridging force in fibrous monolithic ceramics was constructed under the framework of small scale bridging. This formula was applied to predict the fracture resistance or R-curve response of a three-point bending specimen made of fibrous monolithic ceramics. A parametric investigation on the influences of fiber volume fraction, fiber radius, characteristics of constituents, BN's fracture toughness and specimen's geometry on the bridging forces and fracture resistance in Si3N4/BN composite was carried out. The upper and lower limits of the R-curve of Si3N4/BN in small scale bridging were derived. This research revealed the role played by the above parameters in the fracture toughness of fibrous monolithic ceramics.

关键词： fibrous monolithic ceramics fiber bridging R-curve fracture toughness

Investigation of the Surface State of Zeolite HZSM-5 Pretreated with Toluene by Using Fast Atom Bombardment Mass Spectrometry (FABMS)

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Chinese Chemical Letters 1998年第7期9卷 671-674页

作者： Zhu, JH Xu, qh Nanjing Univ Dept Chem Nanjing 210093 Peoples R China

Toluene pretreatment caused many activated toluene species existing on the surface of zeolite HZSM-5, by which the activity of sample was increased. Moreover, variation in the surface Si+/Al+ ratio of HZSM-5 was sensi... 详细信息

关键词： zeolite HZSM-5 surface state FABMS toluene ethylation

Crystal Structure of 5-(l-Menthyloxy)-3-Bromo-4-(R)-(+)-Methylbenzylamino-2(5H)-Furanone

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Chinese Journal of Structural Chemistry 1999年第2期18卷 32-34页

作者： Geng, Z huang, B Chen, qh Capital Normal Univ Dept Chem Beijing 100037 Peoples R China Beijing Normal Univ Dept Chem Beijing 100875 Peoples R China

The crystal structure of the title compound 1, C 22 H 30 BrNO 3, was determined by X ray analysis at 296(1)K. The crystal belongs to othorhombic system, space group P2 12 12 1 with a=9.842(5), b=12.510(5), c=17.763(6) , V=2187(3)  3, Z=4, M r=436.37, D x =1.33 g/cm 3, μ =18.79 cm 1 , F(000) =912 and the final R=0.047 and R w=0.053 for 1429 observed reflections with I≥3σ(I). Structure analysis reveals that the absolute configuration at C 14 of the acetal carbon of the title compound is S.

关键词： crystal structure 2(5H) furanone absolute configuration.

THE DETERMINATION OF AN EQUIVALENT ELASTIC MODULUS FOR BODIES WITH CRACKS BY BOUNDARY ELEMENT METHOD

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Acta Mechanica Solida Sinica 1996年第3期9卷 210-216页

作者： Fei, Q Cen, ZZ Du, qh TSING huA UNIV DEPT MECH ENGNBEIJING 100084PEOPLES R CHINA

The equivalent elastic modulus of cracked bodies with orderly distributed cracks was computed with the boundary element method. A practical self-consistent scheme has been proposed in consideration of the mutual interaction effects of the cracks. The Influence of friction coefficients and orientation of cracks has been investigated. Some computational examples have been given, and the results show that the proposed method is adequate and the scheme is efficient.

关键词： boundary element method self-consistent method equivalent elastic modulus

Clinicopathologic study of primary intestinal B cell malignantlymphoma

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World Journal of Gastroenterology 1999年第6期5卷 538-540页

作者： Zhou Q Xu TR Fan qh Zhen ZX Nanjing Med Univ Affiliated Hosp 1 Dept Pathol Nanjing 210029 Jiangsu Prov Peoples R China

INTRODUCTIONPrimary intestinal B cell lymphoma is one of the most common extra-nodal lymphomas, which includes two types: intestinal mucosa-associated lymphoid tissue lymphoma (IMALToma) and lymphomatous polyposis (LP). Both have characteristic pathologic features, immunophen-otypes and biological behaviors. In this article, twenty-five cases were retrospectively analyzed with regard to criteria of diagnosis and clinicopathologic characteristics.

关键词： lymphoma/pathology intestinal neoplasms/pathology intestinal neoplasms/diagnosis