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Clinical effect of laparoscopic radical resection of colorectal cancer based on propensity score matching

World Journal of Gastrointestinal Surgery 2024年第1期16卷 124-133页

作者： Yang Liu Xian-Xue wang Yu-Lin Li wen-Tao He Hong Li Hua Chen Department of General Surgery Changde HospitalXiangya School of MedicineCentral South University(The First People’s Hospital of Changde City)Changde 415000Hunan ProvinceChina Department of Anesthesiology Changde HospitalXiangya School of MedicineCentral South University(The First People’s Hospital of Changde City)Changde 415000Hunan ProvinceChina

BACKGROUND The incidence of colorectal cancer(CRC)is increasing *** radical resection of CRC is a minimally invasive procedure preferred in clinical *** To investigate the clinical effect of laparoscopic radical resection of CRC on the basis of propensity score matching(PSM).METHODS The clinical data of 100 patients who received inpatient treatment for CRC at Changde Hospital,Xiangya School of Medicine,Central South University(The First People’s Hospital of Changde City)were analyzed *** control group included patients who underwent open surgery(n=43),and those who underwent laparoscopic surgery formed the observation group(n=57).The baseline information of both groups was equipoised using 1×1 *** in the perioperative parameters,inflammatory response,immune function,degree of pain,and physical status between the groups were *** Thirty patients from both groups were successfully *** PSM,baseline data showed no statistically significant differences between the groups:(1)Periop-erative parameters:The observation group had a longer surgery time,less intra-operative blood loss,earlier first ambulation and first anal exhaust times,and shorter gastric tube indwelling time than the control group;(2)Inflammatory response:24 h after surgery,the levels of interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)between groups were higher than ***-6,CRP,and TNF-αlevels in the observation group were lower than in the control group;(3)Immune function:At 24 h after surgery,counts of CD4-positive T-lymphocytes(CD4+)and CD4+/CD8-positive T-lymphocytes(CD8+)in both groups were lower than those before surgery,whereas CD8+was higher than that before *** 24 h after surgery,both CD4+counts and CD4+/CD8+in the observation group were higher than those in the control group,whereas CD8+counts were lower;(4)Degree of pain:The visual analog scale scores in the observation gro

关键词： Colorectal cancer Laparoscopic Open surgery Inflammatory reaction Immune function Propensity score

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Microstructure Characteristics and Elevated Temperature Mechanical Properties of a B Containedβ-solidifiedγ-TiAl Alloy

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 738-746页

作者：王秀琦 GUO Ruiqi 刘国怀 LI Tianrui YANG Yuxuan CHEN Yang XIN Meiling wang Zhaodong State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China School of Materials Science and Engineering Harbin Institute of Technology at ShenzhenShenzhen 518055China School of Metallurgical Engineering Anhui University of TechnologyMaanshan 243000China

The improved microstructure and enhanced elevated temperature mechanical properties of Ti-44Al-5Nb-(Mo,V,B)alloys were obtained by vacuum arc re-melting(VAR)and primary annealing heat treatment(HT)of 1260℃/6 h/Furnace cooling(FC).The phase transformation,microstructure evolution and tensile properties for as-cast and HTed alloys were *** indicate that three main phase transformation points are determined,T_(eut)=1164.3℃,T_(γsolv)=1268.3℃and T_(βtrans)=1382.8℃.There are coarse lamellar colonies(300μm in length)and neighbor reticular B2 andγgrain(3-5μm)in as-cast alloy,while lamellar colonies are markedly refined and multi-oriented(20-50μm)as well as the volume fraction and grain sizes of equiaxedγand B2 phases(about 15μm)significantly increase in as-HTed *** transformations involvingα+γ→α+γ+β/B2 and discontinuousγcoarsening contribute to the above ***(1-3μm)act as nucleation sites forβ_(eutectic) and produce massiveβgrains with different orientations,thus effectively refining the lamellar colonies and forming homogeneous multi-phase *** curves show both the alloys exhibit suitable performance at 800℃.As-cast alloy shows a higher ultimate tensile stress of 647 MPa,while a better total elongation of more than 41%is obtained for as-HTed *** mechanical properties improvement is mainly attributed to fine,multi-oriented lamellar colonies,coordinated deformation of homogeneous multi-phase microstructure and borides within lamellar interface preventing crack propagation.

关键词： TiAl alloy phase transformation heat treatment boride microstructure mechanical properties

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An overview of metal hydroxyfluoride-A novel semiconductor material

ChemPhysMater

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ChemPhysMater 2024年第2期3卷 125-142页

作者： Xingyu Yao Rutao wang Jinbo Zhao Fei Liu Zhidong Jin Zhou wang Fenglong wang Jiurong Liu Lili Wu Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationSchool of Materials Science and EngineeringShandong UniversityJinan250061China School of Materials Science and Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China

Semiconductors have been widely used in many high-tech fields such as photo-and electro-catalysis,ion bat-teries,and solar *** addition to the earliest discovered elemental and compound semiconductors,such as monocrystalline silicon and metal oxides,new types of compound semiconductors have been *** them,metal hydroxyfluorides(MOHF)are an emerging type of semiconductor that are easy to synthesize and ***,many of their properties and applications are not well ***,some MOHF materials,such as ZnOHF and CoOHF,have been sufficiently developed,and their applications have been extensively *** review focuses on a new compound semiconductor,MOHF,with ZnOHF and CoOHF as the *** a short introduction to their physical and chemical properties,their common applications are illustrated with several ***,other less-researched MOHF and MOHF-like materials,as well as their applications,are ***,the expectations and development directions of MOHFs are briefly summarized.

关键词： Metal hydroxyfluoride Semiconductor Functionalmaterials Photocatalysts Electrochemistry

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Segmented Summarization and Refinement:A Pipeline for Long-Document Analysis on Social Media

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Journal of Social Computing 2024年第2期5卷 132-144页

作者： Guanghua wang Priyanshi Garg Weili Wu the Department of Computer Science The University of Texas at DallasRichardsonTX 75080USA

Social media’s explosive growth has resulted in a massive influx of electronic documents influencing various facets of daily ***,the enormous and complex nature of this content makes extracting valuable insights *** document summarization emerges as a pivotal technique in this context,serving to distill extensive texts into concise and comprehensible *** paper presents a novel three-stage pipeline for effective long document *** proposed approach combines unsupervised and supervised learning techniques,efficiently handling large document sets while requiring minimal computational *** methodology introduces a unique process for forming semantic chunks through spectral dynamic segmentation,effectively reducing redundancy and repetitiveness in the summarization *** to previous methods,our approach aligns each semantic chunk with the entire summary paragraph,allowing the abstractive summarization model to process documents without truncation and enabling the summarization model to deduce missing information from other *** enhance the summary generation,we utilize a sophisticated rewrite model based on Bidirectional and Auto-Regressive Transformers(BART),rearranging and reformulating summary constructs to improve their fluidity and *** studies conducted on the long documents from the Webis-TLDR-17 dataset demonstrate that our approach significantly enhances the efficiency of abstractive summarization *** contributions of this paper thus offer significant advancements in the field of long document summarization,providing a novel and effective methodology for summarizing extensive texts in the context of social media.

关键词： long document summarization abstractive summarization text segmentation text alignment rewrite model spectral embedding

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A duplex TaqMan probe-based real-time PCR method for rapid detection and differentiation of the classical and VB strains of human immunodeficiency virus

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Science China(Life Sciences) 2024年第1期67卷 208-210页

作者： Aiping wang Haili wang Jianguo Zhao Yumei Chen Hongliang Liu Peiyang Ding Yan Niu Gaiping Zhang Longhu Laboratory Zhengzhou 450046China School of Advanced Agricultural Sciences Peking UniversityBeijing 100871China

Dear Editor,Human immunodeficiency virus(HIV)is a lentivirus that,if left untreated,can lead to acquired immunodeficiency syndrome(AIDS).The virus can be divided into two types based on genetic differences:HIV-1 and ***-1 is widely distributed worldwide and is the primary strain responsible for the global AIDS epidemic due to its high replication capacity,greater likelihood of transmission,and more severe clinical symptoms(Oeschger et al.,2021).

关键词： immunodeficiency untreated

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自闭症儿童言语和非言语社交沟通技能的游戏式干预模式

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听力学及言语疾病杂志 2024年第1期32卷 75-79页

作者：温雯王树峰谢晴晴高立群北京语言大学语言康复学院北京100083 北京听力协会

社交沟通障碍是自闭症谱系障碍儿童的核心障碍之一,本文介绍了五种可以改善自闭症谱系障碍儿童社交沟通技能的游戏式干预模式。在精准康复理念的指导下,掌握这些方法有利于针对自闭症谱系障碍儿童的社交沟通问题"对症下药",实现个性化... 详细信息

社交沟通障碍是自闭症谱系障碍儿童的核心障碍之一,本文介绍了五种可以改善自闭症谱系障碍儿童社交沟通技能的游戏式干预模式。在精准康复理念的指导下,掌握这些方法有利于针对自闭症谱系障碍儿童的社交沟通问题"对症下药",实现个性化治疗方案指导下的处方性治疗,在解决问题的同时保证自闭症谱系障碍儿童身心的健康发展,并为我国自闭症谱系障碍儿童康复领域的家长、临床工作者和研究者提供借鉴、开拓思路。

关键词：自闭症谱系障碍游戏式干预模式社交沟通技能

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Ultrafast Molecular Movies:Probing Chemical Dynamics with Femtosecond Electron and X-Ray Diffraction

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CCS Chemistry 2024年第5期6卷 1092-1109页

作者： Qianci wang Longteng Yun Jie Yang Center of Basic Molecular Science Department of ChemistryTsinghua UniversityBeijing 100084

Understanding the process of chemical reactions has always been a relentless pursuit for *** development of femtosecond pump-probe techniques since the 1980s has revolutionized the field of chemical dynamics,enabling the capture of timeresolved snapshots of reactions on the femtosecond *** from the 2010s,breakthroughs in femtosecond electron and X-ray sources has enabled ultrafast electron and X-ray diffraction techniques,which is able to directly reveal the temporal evolution of atomic geometries of molecules,allowing for the creation of molecular ***-phase molecular movies reveal intrinsic intramolecular processes,while liquid-phase molecular movies provide insights for complicated solvent-solute *** minireview focuses on the advances in studying gasphase and liquid-phase molecular dynamics(MD)using ultrafast electron and X-ray diffraction techniques on femtosecond and picosecond *** fast-developing experimental capability of the direct observation of molecular structural evolution during chemical reactions,on its natural femtosecond timescale and subangstrom length scale,offers tremendous potential for the field of chemical kinetics and MD.

关键词： molecular movie electron diffraction X-raydiffraction femtosecond gasphase liquidphase

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Risk mapping of wildlife-vehicle collisions across thestate of Montana,USA:a machine-learning approach forimbalanced data along rural roads

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Transportation Safety and Environment 2024年第3期6卷 124-132页

作者： Matthew Bell Yiyi wang Rob Ament Western Transportation Institute Montana State University2327 University WayBozemanMT 59717USA School of Engineering San Francisco State University1600 Holloway AveSan FranciscoCA 94132USA

Wildlife-vehicle collisions(WVCs)with large animals are estimated to cost the USA over 8 billion USD in property damage,tens of thousands of human injuries and nearly 200 human fatalities each *** WVCs occur on rural roads and are not collected evenly among road segments,leading to imbalanced *** are a disproportionate number of analysis units that have zero WVC cases when investigating large geographic areas for collision *** units with zero WVCs can reduce prediction accuracy and weaken the coefficient estimates of statistical learning *** study demonstrates that the use of the synthetic minority over-sampling technique(SMOTE)to handle imbalanced WVC data in combination with statistical and machine-learning models improves the ability to determine seasonal WVC risk across the rural highway network in Montana,*** array of regularized variables describing landscape,road and traffic were used to develop negative binomial and random forest models to infer WVC rates per 100 million vehicle miles *** random forest model is found to work particularly well with SMOTE-augmented data to improve the prediction accuracy of seasonal WVC ***-augmented data are found to improve accuracy when predicting crash risk across fine-grained grids while retaining the characteristics of the original *** analyses suggest that SMOTE augmentation mitigates data imbalance that is encountered in seasonally divided WVC *** research provides the basis for future risk-mapping models and can potentially be used to address the low rates of WVCs and other crash types along rural roads.

关键词： wildlife-vehicle collisions machine learning SMOTE negative binomial risk mapping

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Efficacy and safety of fecal microbiota transplantation for treatment of ulcerative colitis:A post-consensus systematic review and metaanalysis

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World Journal of Clinical Cases 2024年第21期12卷 4691-4702页

作者： Jin-Tao Zhang Nan Zhang Xue-Tao Dong Xiao-Ran wang Hong-wen Ma Yan-Di Liu Mu-Ran Li Department of Clinical Medicine School of MedicineNankai UniversityTianjin 300071China Department of Gastroenterology Tianjin Union Medical CenterTianjin 300122China

BACKGROUND Numerous studies have assessed the efficacy and safety of fecal microbiota transplantation(FMT)as a therapy for ulcerative colitis(UC).However,the treatment processes and outcomes of these studies *** To evaluate the efficacy and safety of FMT for treating UC by conducting a systematic *** The inclusion criteria involved reports of adult patients with UC treated with FMT,while studies that did not report clinical outcomes or that included patients with infection were *** remission(CR)and endoscopic remission(ER)were the primary and secondary outcomes,*** We included nine studies retrieved from five electronic *** FMT group had better CR than the control group[relative risk(RR)=1.53;95%confidence interval(CI):1.19-1.94;P<0.0008].ER was statistically significantly different between the two groups(RR=2.80;95%CI:1.93-4.05;P<0.00001).Adverse events did not differ significantly between the two *** FMT demonstrates favorable performance and safety;however,well-designed randomized clinical trials are still needed before the widespread use of FMT can be ***,standardizing the FMT process is urgently needed for improved safety and efficacy.

关键词： Fecal microbiota transplantation Randomized clinical trials Remission Ulcerative colitis Meta-analysis

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Influence of biological treatments on intestinal microbiota of psoriasis patients

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Chinese Medical Journal 2024年第16期137卷 1996-1998页

作者： Zhuyuan wen Xiaoling Lu Hao Nie Jing Xu Yang Zou Kun Huang Aijun Chen Yichi Zhang Min Cao Qi Yin Ping wang Department of Dermatology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China School of Pediatrics Chongqing Medical University Pediatric CollegeChongqing 400016China School of Public Health Chongqing Medical UniversityChongqing 400016China Department of Urology Third People’s Hospital of ChengduChengduSichuan 610014China

To the Editor:Psoriasis is a common,chronic inflammatory skin disease occurring worldwide and presenting at any age.[1]Biologics are the most important therapeutic advances in psoriasis treatment.[2]With the development of 16S rRNA sequencing technology,the association between psoriasis and intestinal flora has been gradually *** bacteria secrete short-chain fatty acids(SCFAs)with anti-inflammatory properties,serving as active microbial metabolites that regulate the function of immune cells in the intestine and other tissues.[3]However,the impact of biological treatment on gut microbiota and related functional changes in psoriasis patients remains *** study aimed to explore the effects of biological treatments on the intestinal microbiota of psoriasis patients.

关键词： psoriasis patients intestine

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