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Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 37-42页

作者： Maissa ben Thayer Fatma Khanchel Imen Helal Dorra Chiboub Hedhli Raoueh Ehsen ben Brahim Raja Jouini Aschraf Chadli-Debbiche Faculty of Medicine of Tunis Tunis El Manar UniversityTunisTunisia Depatment of Pathology Habib Thameur's HospitalTunisTunisia Department of Otorhinolaryngology-Head and Neck surgery Habib Thameur's HospitalTunisTunisia

Background:Thyroid carcinoma(TC)accounts for almost 0.5%–1%of total *** incidence is increasing rapidly *** studies have drawn up the epidemiological profile of TC and its clinical and pathological ***,to date,no similar studies have been conducted in ***:To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our *** and Methods:We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4-year ***:We collected a sample of 192 cases of *** consisted of 31 males and 161 females(83.8%)with a sex-ratio M/F of *** mean age was 46.4 *** thyroid carcinoma was the most frequent histological *** multifocality rate was 33.8%.The mean size of TC was 2.2±1.9 cm.60.9%of TC were staged pT1 and 20.3%had nodal *** thyroid microcarcinomas were noted in 37.5%of ***:Our results were consistent with those of the literature.A high proportion of pT1 and pN0 tumors were noted in our series,suggesting that TC's diagnosis and management was performed at an early stage of the disease in our *** addition,our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our *** studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.

关键词： coronavirus disease 19 epidemiology papillary thyroid carcinoma papillary thyroid microcarcinoma pathology thyroid carcinoma

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Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia

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World Journal of Gastroenterology 2010年第4期16卷 479-483页

作者： Imen Sfar Walid ben Aleya Leila Mouelhi houda Aouadi Thouraya ben Rhomdhane Mouna Makhlouf Salwa Ayed-Jendoubi houda Gargaoui Taoufik Najjar Taieb ben Abdallah Khaled Ayed Yousr Gorgi Laboratory of Immunology Charles Nicolle HospitalTunis 1006Tunisia Department of Gastroenterology Charles Nicolle HospitalTunis 1006Tunisia

AIM:To assess the possible association between PTPN22(R620W) gene polymorphism and inflammatory bowel disease(IBD).METHODS:One hundred and sixty-four patients with IBD 105 Crohn's disease(CD) and 59 ulcerative colitis(UC) and 100 healthy controls were *** of the PTPN22 gene 1858C→T polymorphism was performed by restriction fragment length polymorphism-polymerase chain reaction with Rsa Ⅰ ***:The genotypic and allelic frequencies of(R620W) PTPN22 gene polymorphism reveal a significant association of the PTPN22 620-W allele with IBD,compared to the healthy control group(OR:17.81,95% CI:4.18-21.86,P = 0.00001).Nevertheless,nodifference in this polymorphism was found between CD and UC *** significant association was found between the frequencies of genotypes of the PTPN22 gene with either the clinical features such as sex,age,age at disease onset,and extent of colitis,or the production of serological markers(anti-Saccharomyces cerevisiae antibody in CD and perinuclear anti-neutrophil cytoplasmic antibody in UC).CONCLUSION:These observations confirm the association of IBD susceptibility with the PTPN22 1858T(620-W) allele in Tunisian patients.

关键词： Inflammatory bowel disease PTPN22 Genetic polymorphism Genetic susceptibility

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光量子精密测量研究进展(特邀)

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中国激光 2024年第1期51卷 354-368页

作者：王犇张利剑南京大学现代工程与应用科学学院江苏南京210023 智能光传感与调控技术教育部重点实验室江苏南京210023 人工微结构科学与技术协同创新中心江苏南京210023 南京大学固体微结构物理国家重点实验室江苏南京210023

量子精密测量作为当代量子力学的主要应用方面之一,近些年来一直是量子科技的重要研究和发展方向。量子精密测量的主要研究目标是针对物理系统中的未知参数,利用量子资源进行量子增强测量,以提升参数测量精度。与其他物理系统相比,光子... 详细信息

量子精密测量作为当代量子力学的主要应用方面之一,近些年来一直是量子科技的重要研究和发展方向。量子精密测量的主要研究目标是针对物理系统中的未知参数,利用量子资源进行量子增强测量,以提升参数测量精度。与其他物理系统相比,光子系统具有相干时间长、不易受到环境干扰等优越性,因而常被用作量子信息处理的载体。以光子为基础的传感器提升传感精度是光量子精密测量的主要任务。介绍了量子精密测量的一般性原理,给出参数估计的量子极限精度下界。同时,介绍了目前光量子精密测量的理论与实验研究进展以及相应的挑战。

关键词：量子光学量子精密测量参数估计海森堡极限传感

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Quasi-three-dimensional hydrodynamics of the corona region of laser irradiation of a slab

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Chinese Physics B 2024年第8期33卷 351-360页

作者：董晓梅关本金李英骏 State Key Laboratory for Tunnel Engineering China University of Mining and TechnologyBeijing 100083China

This paper introduces and establishes a quasi-three-dimensional physical model of the interaction between a laser and a slab *** contrast to previous one-dimensional analytical models,this paper innovatively fits the real laser conditions based on an isothermal,homogeneous expansion similarity solution of the ideal hydrodynamic *** this simple model,the evolution law and analytical formulae for key parameters(e.g.,temperature,density and scale length)in the corona region under certain conditions are *** analytical solutions agree well with the relevant results of computational hydrodynamics *** constant laser irradiation,the analytical solutions provide a meaningful power-law scaling *** model provides a set of mathematical and physical tools that give theoretical support for adjusting parameters in experiments.

关键词： plasma self-similarity method fluid dynamics calculations

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RDA注册表——走向网络时代编目工作的基础

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图书馆建设 2024年第4期 4-8页

作者：顾犇国家图书馆

1 RDA概况《英美编目条例》(Anglo-American Cataloguing Rules,简称AACR)是美国、英国、加拿大图书馆界共同制订的主要适用于西方语文文献资料的图书馆编目规则。1967年出版第1版(AACR1),1978年出版第2版(AACR2),1988年出版AACR2的修订... 详细信息

1 RDA概况《英美编目条例》(Anglo-American Cataloguing Rules,简称AACR)是美国、英国、加拿大图书馆界共同制订的主要适用于西方语文文献资料的图书馆编目规则。1967年出版第1版(AACR1),1978年出版第2版(AACR2),1988年出版AACR2的修订版,1990年出版AACR2第2版,已经成为事实上的国际性编目规则,并被各国用于制定本国编目规则的参考依据。

关键词： AACR2 编目规则图书馆编目编目工作加拿大图书馆注册表文献资料 RDA

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人与野生动物共存研究进展

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生态学报 2024年第3期44卷 885-892页

作者：马奔雷硕中国人民大学环境学院北京100872 中国环境科学研究院生态研究所北京100012

人类和野生动物生存空间高度重叠,冲突不可避免,如何从冲突走向共存是学术研究的热点和难点。研究评述了人与野生动物共存的概念解析、量化评估、影响因素以及实现机制四方面的进展,发现人与野生动物共存的概念定义和量化评估还存在争... 详细信息

人类和野生动物生存空间高度重叠,冲突不可避免,如何从冲突走向共存是学术研究的热点和难点。研究评述了人与野生动物共存的概念解析、量化评估、影响因素以及实现机制四方面的进展,发现人与野生动物共存的概念定义和量化评估还存在争议。大多研究认为共存并不意味着没有冲突,而是不可避免的冲突被控制在可容忍范围内。研究多采用容忍度、接受度、保护态度和行为等变量对人与野生动物共存状态进行量化。野生动物相关的成本效益是影响人与野生动物共存的关键因素。经济和教育手段是实现共存的重要路径。经济手段包括补偿、保险、生态旅游、保护投资等措施,通过增加野生动物保护效益、减少保护成本可以实现共存。教育手段通过提升社区保护意识和野生动物保护效益感知、增强冲突应对能力实现人与野生动物共存。未来研究可以从生态和生计视角构建主客观相结合的指标体系对人与野生动物共存进行量化;基于社会生态系统框架识别影响人与野生动物共存的关键因素,总结实现共存的成功经验;采用实验经济学方法探索适用于本土的多样化共存干预措施组合。

关键词：人与野生动物共存容忍度成本效益经济手段

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2型糖尿病合并外周动脉斑块与凝血功能的相关性

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海军军医大学学报 2024年第9期45卷 1174-1179页

作者：陈犇鲁瑾海军军医大学(第二军医大学)第一附属医院内分泌科上海200433

目的探讨凝血功能与2型糖尿病患者合并外周动脉斑块的相关性。方法纳入2022年5-8月在我院内分泌科住院治疗的2型糖尿病患者269例,分别根据有无颈动脉斑块和有无下肢动脉斑块将患者分为颈动脉斑块组(131例)和无颈动脉斑块组(138例)、下... 详细信息

目的探讨凝血功能与2型糖尿病患者合并外周动脉斑块的相关性。方法纳入2022年5-8月在我院内分泌科住院治疗的2型糖尿病患者269例,分别根据有无颈动脉斑块和有无下肢动脉斑块将患者分为颈动脉斑块组(131例)和无颈动脉斑块组(138例)、下肢动脉斑块组(134例)和无下肢动脉斑块组(135例)。比较各组患者的一般临床资料及凝血功能指标的差异,采用logistic回归分析评估2型糖尿病合并外周动脉斑块的独立影响因素。结果颈动脉斑块组患者的纤维蛋白原水平高于无颈动脉斑块组[3.15(2.79,3.79)g/L vs 2.99(2.66,3.42)g/L,P=0.005]。logistic回归分析显示,纤维蛋白原为2型糖尿病合并颈动脉斑块的独立危险因素(OR=1.338,95%CI 1.061~2.078,P0.05)。结论2型糖尿病合并不同部位外周动脉斑块与凝血功能的相关性不同。合并颈动脉斑块的患者纤维蛋白原水平较无颈动脉斑块的患者升高,且在控制其他混杂因素后纤维蛋白原是颈动脉斑块发生的独立危险因素;而合并下肢动脉斑块与凝血功能指标无关。

关键词： 2型糖尿病颈动脉斑块下肢动脉斑块纤维蛋白原

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MXene@c-MWCNT Adhesive Silica Nanofiber Membranes Enhancing Electromagnetic Interference Shielding and Thermal Insulation Performance in Extreme Environments

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Nano-Micro Letters 2024年第10期16卷 82-98页

作者： Ziyuan Han Yutao Niu Xuetao Shi Duo Pan Hu Liu Hua Qiu Weihua Chen ben Bin Xu Zeinhom MEl-Bahy Hua Hou Eman Ramadan Elsharkawy Mohammed AAmin Chuntai Liu Zhanhu Guo Key Laboratory of Materials Processing and Mold(Zhengzhou University) Ministry of EducationNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450002People's Republic of China School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026People's Republic of China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Advanced Materials DivisionSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123People's Republic of China Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi'an 710072People's Republic of China College of Chemistry&Green Catalysis Center Zhengzhou UniversityZhengzhou 450001People's Republic of China Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle Upon Tyne NE18UK Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr City 11884CairoEgypt Department of Chemistry Faculty of ScienceNorthern Border UniversityArarSaudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia

A lightweight flexible thermally stable composite is fabricated by com-bining silica nanofiber membranes(SNM)with MXene@c-MWCNT hybrid *** flexible SNM with outstanding thermal insulation are prepared from tetraethyl orthosilicate hydrolysis and condensation by electrospinning and high-temperature calcination;the MXene@c-MWCNT_(x:y)films are prepared by vacuum filtration *** particular,the SNM and MXene@c-MWCNT_(6:4)as one unit layer(SMC_(1))are bonded together with 5 wt%polyvinyl alcohol(PVA)solution,which exhibits low thermal conductivity(0.066 W m^(-1)K^(-1))and good electromagnetic interference(EMI)shielding performance(average EMI SE_(T),37.8 dB).With the increase in func-tional unit layer,the overall thermal insulation performance of the whole composite film(SMC_(x))remains stable,and EMI shielding performance is greatly improved,especially for SMC_(3)with three unit layers,the average EMI SET is as high as 55.4 *** addition,the organic combination of rigid SNM and tough MXene@c-MWCNT_(6:4)makes SMC_(x)exhibit good mechanical tensile ***,SMC_(x)exhibit stable EMI shielding and excellent thermal insulation even in extreme heat and cold ***,this work provides a novel design idea and important reference value for EMI shielding and thermal insulation components used in extreme environmental protection equipment in the future.

关键词： SiO_(2)nanofiber membranes MXene@c-MWCNT Composite film Thermal insulation Electromagnetic interference shielding

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Flexible dual-Janus porous membrane for underwater gas bubbles anti-buoyancy unidirectional transportation

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Science China Chemistry 2024年

作者： Shuang ben Han Ma Rui Liu Yuzhen Ning Zhihong Zhao Xudong Zhang Qiang Li Kesong Liu School of Materials Science and Engineering Shenyang Ligong University Tianmushan Laboratory School of Equipment Engineering Shenyang Ligong University Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology School of Chemistry Beihang University School of Mechanical Engineering and Automation Beihang University

Controllable transportation of bubbles in surfactant or aqueous is very important in daily chemical products, food fermentation,mineral flotation and other fields. However, bubbles are mainly dominated by buoyancy and move upward in solution, which makes the manipulation of bubbles difficult. Although some progress has been made in controlling underwater bubbles,achieving continuous transportation and collection of underwater bubbles without relying on external forces is still a great challenge. To this end, we bionically designed a flexible polydimethylsiloxane(PDMS) porous surface with dual-Janus characteristics. Namely, a porous PDMS membrane integrating structural gradient and wettability gradient realizes the underwater anti-buoyancy unidirectional transportation of bubbles without external force input, and possesses the capability of underwater gas anti-buoyancy transportation and storage. This work provides inspiration and direction for the development and design of underwater gas transportation and storage devices and provides innovative thinking for the implementation of seabed carbon dioxide storage technology.

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Prevention of H2O2 Induced Oxidative Damages of Rat Testis by Thymus algeriensis

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Biomedical and Environmental Sciences 2016年第4期29卷 275-285页

作者： Fatma Guesmi Hamida Beghalem Amit K Tyagi Manel ben Ali Ramla ben Mouhoub houda Bellamine Ahmed Landoulsi Laboratory of Biochemistry and Molecular Biology Faculty of Sciences of Bizerte Zarzouma Bizerte 7021 Tunisia Cytokine Research Laboratory Department of Experimental Therapeutics The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Boulevard Houston TX 77030 USA Laboratory of Biomonitoring of the Environment (LRO1/ES14) Faculty of Sciences of Bizerte Zarzouma Bizerte 7021 Tunisia Service of Anatomo-Pathology of Menzel Bourguiba Bizerte 7050 Tunisia

Objective We evaluate the effects of Thymus algeriensis （TEO） against hydrogen peroxide （H202） toxicity on body and testis weight, testis sperm count, testis lipid peroxidation, and antioxidant enzyme activities in rats. Methods Rats were treated with low （LD） and high dose （HD） of H202 （0.1 and 1 mmol/L） in the presence or absence of TEO （150 mg/kg）. Results The results exhibited a significant decrease in body weight and testis weight, in total sperm number decrease （P〈0.05）, sperm motility and percentage of sperm viability, leading to complete arrest, in sperm flagellar beat frequency by the gavage of 1 mmol/L H202 compared to controls. The administration of H2O2 resulted in a significant reduction in testis GSH, GPx, CAT, SOD, and GST activity and significant increase （P〈0.05） in MDA concentration compared with the untreated control animals. TEO pre-treatment protected testis from the H2O2 generated oxidative stress. These results were confirmed by histological architecture examinations. Conclusion H2O2 has the ability to alter the sperm function, characteristics and development of testis. However, TEO is an efficient natural agent, which can prevent the testis from H2O2-induced oxidative damage in rats.

关键词： Testis Hydrogen peroxide TEO Antioxidants Infertility

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