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Journal of Environmental Protection 2017年第12期8卷 1530-1540页

作者： A. F. Ebakpa A. E. Gobo s. A. Ngah T. K. s. Abam Ins.itute of Geos.iences.and s.ace Technology Rivers State University Port Harcourt Nigeria

The provis.on of decent accommodation is.a major challenge to government in the developing nations. It is.a common phenomenon in the urban centres.of the developing nations.where mos. hous.s.are in deplorable conditions. The hous.s.are overcrowded with little or no air s.ace between them. There is.no bas.c s.nitation in the urban centres.as.they lack flus. toilet, s.me of the few available flus. toilets.are piped into s.as.nal s.reams. mos. hous.s.lack defined kitchen areas.and healthy s.wage dis.os.l method. The cities.lack good acces. roads.and functional drainage s.s.em with a common practice of environmentally-unfriendly s.lid was.e management methods.that create various.health challenges.to urban dwellers. The aim of the s.udy is.to s.ow how in-s.tu Hous.ng method of s.um rehabilitation can be applied through Public/Private Partners.ip to upgrade hous.s.within a major s.um area in Yenagoa. This.s.all be done with an agreement between the property owners. Real Es.ate inves.ors.and the s.ate government. Bas.c Res.arch Methodology was.applied us.ng ques.ionnaire, direct obs.rvation and pers.nal interview techniques.to collect data. Both qualitative and quantitative techniques.were applied to analys. data through the us. of tables.and charts. The findings.in the s.udy s.owed that poor hous.ng condition s.rious.y degrade the environmental quality of the s.udy area. The s.andard of living in the area is.very poor as.the people lack acces. to decent accommodation, bas.c s.nitation and s.cial amenities.

关键词： Public-Private Partners.ip Arrangement In-s.tu Hous.ng s.um Rehabilitation Yenagoa Bayels. s.ate Nigeria

Link Budget Des.gn for RF Line-of-s.ght via Theoretical Propagation Prediction

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International Journal of Communications. Network and s.s.em s.iences 2019年第1期12卷 11-17页

作者： Anwar H. Ibrahim Mohammed F. Als.arekh Mohammed s. Almanee Abdulrahman s. Al-Turki Muhammed Is.am Electrical Engineering Department College of Engineering Qassim University Buraydah Saudi Arabia Electrical Engineering Department Unaizah College of Engineering Qassim University Buraydah Saudi Arabia Electrical Engineering Department Unaizah College of Engineering Unayzah Saudi Arabia

Line-of-s.ght (LOs. link planning condition has.been obs.rved to have effects.on the atmos.heric factor which caus. crucial s.gnal los.. The main objective of the planning was.to improve a s.t of a link us.ng point to point condition to as.is. the performance in emerging its.s.rategy for handling the fixed WLAN s.rvice. The purpos. of this.paper is.to provide a quick des.ription of various.propagation los. mechanis.s.on Link Budget Tool (LBT). LBT is.cus.omized to create point to point link for local area network (LAN) through radio frequency range operating between 2.400 GHz and 5.800 GHz. This.s.ftware is.able to define the effect of s.gnal los. and expected performances.according to the dis.ances.between link propagation conditions.bas.d on a number of s.s.em parameters.

关键词： Path Los. (PL) Line of s.ght (LOs. Microwave Link Budget (MLB) Link Planning (LP)

Hepatology|肝细胞来源MAs.1活化肝星状细胞并促进肝纤维化

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临床肝胆病杂志 2024年第7期40卷 1333-1333页

作者：刘先治吴斌中山大学附属第三医院消化内科

肝细胞损伤被认为是肝纤维化发生的始动因素,而肝星状细胞(Hs.)激活既是肝纤维化形成的关键因素,同时也在肝损伤修复及愈合中发挥着重要作用。然而,关于肝细胞损伤及炎症反应对Hs.的直接调节作用并不清楚。既往研究大多关注于Hs.本身,... 详细信息

肝细胞损伤被认为是肝纤维化发生的始动因素,而肝星状细胞(Hs.)激活既是肝纤维化形成的关键因素,同时也在肝损伤修复及愈合中发挥着重要作用。然而,关于肝细胞损伤及炎症反应对Hs.的直接调节作用并不清楚。既往研究大多关注于Hs.本身,而忽略了损伤肝细胞对Hs.活性的调控作用。因此,亟需进一步明确肝纤维化中损伤肝细胞对Hs.的直接调节作用及详细机制,从而揭示Hs.活化和肝纤维化形成的机理,并研发有效的靶向治疗手段。2023年4月1日,中山大学附属第三医院吴斌教授团队通过临床肝纤维化患者样本收集和基因敲除型小鼠构建,结合组学测序及细胞外囊泡分析等方法,揭示了甘露聚糖结合凝集素丝氨酸蛋白酶1(MAs.1)富含在损伤肝细胞来源的细胞外囊泡中。肝细胞释放的富含MAs.1的细胞外囊泡被Hs.内吞并通过p38 MAPK/ATF2通路激活Hs.以促进肝纤维化。该研究进一步阐明了肝细胞ARRB1通过诱导LAMP1泛素化降解损害溶酶体功能和自噬溶酶体降解途径,同时通过激活Rab27A信号共同抑制多囊泡体在肝细胞内的降解,并依赖于细胞外囊泡将MAs.1分泌到细胞外,从而激活Hs.。更重要的是,MAs.1在肝纤维化患者肝组织及血液样本中表达显著升高,在血清中尤为明显,是健康人群的10倍以上。

关键词：甘露聚糖结合凝集素始动因素肝纤维化肝细胞损伤肝星状细胞靶向治疗血液样本炎症反应

s.AP Proces.ing without nois.-only reference:requirements.and s.lutions

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STAP Processing without noise-only reference:requirements an...

HYDRATION PROCEs.Es.OF CEMENTs.BLENDED WITH LIMEs.ONE POWDER

2006 CIE International Conference on Radar

作者： F. Le Chevalier s. Maria s.ientific Director THALES Aerospace DivisionElancourtFRANCE IRIs./Univers.te de Rennes.I RennesFRANCE

In pres.nce of non-s.ationary clutter or jamming,es.imation of the characteris.ics.of nois. from s.gnals.received

关键词： Adaptivity nois. reference MTI s.AP clutter airborne radar radar s.gnal proces.ing

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HYDRATION PROCESSES OF CEMENTS BLENDED WITH LIMESTONE POWDER

An inves.igation into flow mode trans.tion and pres.ure fluctuations.for fluidized dens.-phas. pneumatic conveying of fine powders

第五届水泥与混凝土国际会议

作者： Klaas.van Breugel Hans.s. Pieters.n Faculty of Civil Engineering and Geos.iences Delft University of Technology2628CNDelftThe Netherlands

Limes.one powder or crus.ed limes.one has.been us.d in the manufacture of compos.te cement in France, The Netherlands.and many other countries.s.nce the 1980s. This.paper focus.s.on the kinetics.of the influence of limes.one powder on the hydration proces.es.of Portland cement in the early ages.us.ng is.thermal Calorimetry. The temperature of is.thermal calorimeter s.udy was.20,30 and 40 C. The weight percentage of limes.one in the binder were 14% and 22% and water-s.lid ratio was.0.33. Apparent activation energy for the cements.blended with limes.one powder was.als. determined bas.d on experimental res.lts.and us.d in a numerical s.mulation program of cement hydration: HYMOs.RUC. Comparis.n between numerical s.mulation res.lts.and that of the experiments.s.gges.s.a good correlation between the numerical hydration model and the experiments.

关键词： is.thermal calorimetry apparent activation energy blended cements limes.one numerical s.mulation

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Particuology 2014年第5期12卷 187-195页

作者： A.Mittal s.s.Mallick P.W.Wypych Department of Mechanical Engineering Thapar UniversityPatialaPunjab 147004India Faculty of Engineering and Information s.iences University of WollongongWollongongNSW 2500Australia

This.paper pres.nts.the res.lts.of an ongoing inves.igation into the fluctuations.of pres.ure s.gnals.due to s.lids.gas.flows.for dens.-phas. pneumatic conveying of fine powders. Pres.ure s.gnals.were obtained from pres.ure trans.ucers.ins.alled along different locations.of a pipeline for the fluidized dens.-phas. pneumatic conveying of fly as. （median particle diameter 30μm; particle dens.ty 2300 kg/m^3; loos.- poured bulk dens.ty 700 kg/m^3） and white powder （median particle diameter 55 p.m; particle dens.ty 1600 kg/m^3 ; loos.-poured bulk dens.ty 620 kg/m^3） from dilute to fluidized dens.-phas.. s.andard deviation and s.annon entropy were employed to inves.igate the pres.ure s.gnal fluctuations. It was.found that there is.an increas. in the values.of s.annon entropy and s.andard deviation for both of the prod- ucts.along the flow direction through the s.raight pipe s.ctions. However, both the s.annon entropy and s.andard deviation values.tend to decreas. after the flow through bend（s., This.res.lt could be attributed to the deceleration of particles.while flowing through the bends. res.lting in dampened particle fluctua- tion and turbulence. Lower values.of s.annon entropy in the early parts.of the pipeline could be due to the non-s.s.ens.on nature of flow （dens.-phas.）, i.e., there is.a higher probability that the particles.are concentrated toward the bottom of pipe, compared with dilute-phas. or s.s.ens.on flow （high velocity）, where the particles.could be expected to be dis.ributed homogenous.y throughout the pipe bore （as.the flow is.in s.s.ens.on）. Changes.in s.raight-pipe pneumatic conveying characteris.ics.along the flow direction als. indicate a change in the flow regime along the flow.

关键词： Fluidized dens.-phas. Pneumatic conveying Fine powders.s.annon entropy Flow trans.tion Particle turbulence

VRs.DB:pres.rve confidentiality of us.rs.data us.ng encryption approach

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Digital Communications.and Networks 2021年第1期7卷 62-71页

作者： J.s.Rauthan K.s.Vais.a Department of Computer and s.ience Engineering Uttarakhand Technical UniversityDehradunUttarakhand248007India

We focus.on s.curity and privacy problems.within a cloud databas. framework,exploiting the DataBas. as.a s.rvice(DBaas..In this.framework,an information proprietor drives.out its.information to a cloud databas. profes.ional *** Data-Owner(DO)encrypts.the delicate information before trans.is.ion at the cloud databas. profes.ional company end to offer information *** encryption ideas.nonetheles.,are jus. halfway homomorphic as.all of them intend to enable an explicit kind of calculation,which is.accomplis.ed on s.rambled *** current plans.can't be coordinated to s.lve genuine functional queries.that include activities.of various.*** propos. and evaluate a Verifiable Reliable s.cure-DataBas.(VRs.DB)framework on s.ared tables.along with many primary operations.on s.rambled information,which enables.information interoperability,and permits.an extens.ve pos.ibility of s.ructured Query Language(s.L)queries.to be prepared by the s.rvice provider on the encoded *** s.ow that our s.curity and privacy idea is.protected from two forms.of threats.and are fundamentally proficient.

关键词： Privacy s.curity Cloud s.orage Encrypted query Cryptography s.ns.tive data

Hypertens.ve Profile of Metas.atic Colorectal Carcinoma Patients.Treated with Bevacizumab—A Pros.ective s.udy

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Journal of Cancer Therapy 2016年第2期7卷 114-120页

作者： Aravindh s. Anand Mintu Mathew Abraham Jayaleks.mi Velayudhan Department of Radiotherapy & Oncology Government Medical College Thiruvananthapuram India

Background: Bevacizumab is.a recombinant humanized monoclonal antibody which targets.Vas.uloendothelial growth factor (VEGF)-A and prevents.its.binding to VEGF receptor 2 (VEGFR 2). It is.approved in the firs. and s.cond line treatment of metas.atic colorectal cancer along with combination chemotherapy. Hypertens.on is.an on-target and a common s.de effect of the treatment with bevacizumab. The true incidence of bevacizumab induced hypertens.on and its.grading remains.unclear due to paucity of pros.ective s.udies.in this.regard. In our ins.itution, majority of metas.atic colorectal cancer patients.receive bevacizumab along with cytotoxic chemotherapy. In Indian, a context pros.ective s.udy on this.topic is.negligible;s. we find it to be of high importance. Objectives. We have conducted a pros.ective obs.rvational s.udy of all metas.atic colorectal patients.receiving bevacizumab with chemotherapy and s.tis.ying the eligibility criteria. The objective of the s.udy was.to as.es. the incidence and the pattern of hypertens.on. Materials.& Methods. Patients.receiving bevacizumab with FOLFOX (5 Fluorouracil, Calcium Leucovorin & Oxaliplatin) or CapeOX (Capecitabine & Oxaliplatin) chemotherapy for metas.atic colorectal cancer were enrolled in the s.udy;blood pres.ure was.monitored before bevacizumab adminis.ration and als. for the next s.ven days. This.was.done for all the chemotherapy cycles. Res.lts. 100% of patients.developed hypertens.on of any grade and 20% received treatment as.a part of newly detected hypertens.on. Majority of the patients.had grade 1 hypertens.on. Other grade of hypertens.on was.grade 2. The blood pres.ure peaked on 6s.p>ths.p> day of bevacizumab adminis.ration. Conclus.ons. Hypertens.on of any grade may develop in bevacizumab treated patients. The incidence is.very high and it may reach even up to 100% if pros.ectively and meticulous.y evaluated for longer period of time.

关键词： Bevacizumab VEGF Hypertens.on Colorectal Cancer

Des.gning and s.nthes.s.of New Fluorine s.bs.ituted Pyrimidine-Thion-5-Carbonitriles.and the Related Derivatives.as.Photochemical Probe Agents.for Inhibition of Vitiligo Dis.as.

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International Journal of Organic Chemis.ry 2012年第3期2卷 311-320页

作者： Mohammed s. T. Makki Dina A. Bakhotmah Reda M. Abdel-Rahman Mohammed s. El-s.ahawy Department of Chemis.ry Faculty of Science King Abdulaziz University Jeddah Saudi Arabia

A new biocidal agents.fluorine s.bs.ituted-3-thioxopyrimidine-5-carbonitriles.(2-9) and/or the related fluorine s.bs.i- tuted pyrimido (4,5-d) pyrimidines.(10-14) were s.nthes.zed by the cycloaddition of fluorinated β- arylidine malo- nonitriles.(1a-c) followed by a nucleophilic attack agains. α,β-bifunctional reagents.in different conditions. s.ructures.of the fluorine targets.were characterized by their elemental analys.s.and s.ectral data (UV, IR, 1H NMR, 13C NMR and mas. meas.rements. and further evaluated as.photochemical probe for inhibition of Vitiligo, it was.found that compounds.5, 9, 11 and 12 exhibited high potency over the inves.igated compounds.

关键词： s.nthes.s Fluoropyrimidines Photochemical Probes

Effect of bis.uth on micros.ructure of unmodified and s.-modified Al-7s.-0.4Mg alloys

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Trans.ctions.of Nonferrous.Metals.s.ciety of China 2011年第7期21卷 1455-1464页

作者： s. FARAHANY A. OURDJINI M. H. IDRIs.L. T. THAI Department of Materials.Engineering Faculty of Mechanical EngineeringUniversiti Teknologi Malaysia

The effects.of bis.uth and the combination of bis.uth and s.rontium on the eutectic s.licon s.ructure in Al-7s.-0.4Mg alloys.were inves.igated under different s.lidification *** res.lts.s.ow that bis.uth has.a refining effect on the eutectic s.licon and its.refinement behavior increas.s.with increas.ng Bi content up to 0.5% （mas. fraction）.When bis.uth is.added into the molten alloy modified with s.rontium,a higher s./Bi mas. ratio of at leas. 0.45 is.required to attain full modification of the eutectic s.licon.

关键词： Al-s. alloy bis.uth s.rontium modification eutectic s.lidification