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Bladder Cancer: Epidemiological, Clinical and Histopathological Aspects at the University Hospital Point G, Mali

Open Journal of Urology 2021年第10期11卷 343-350页

作者： honoré jean gabriel berthé Dramane Cissé Moussa Salifou Diallo Amadou Kassogué Alkadri Diarra Mamadou Tidiani Coulibaly Mamadou Lamine Diakité Modibo Coulibaly Mory Koné Université des Sciences des Techniques et des Technologies de Bamako Bamako Mali CHU du Point G Bamako Bamako Mali Hô pital Sominé DOLO de Mopti Mopti Mali CHU Kati Kati Mali CHU Luxembourg Bamako Mali CHU gabriel TOURE Bamako Bamako Mali

Introduction: Bladder cancer is a new tissue formation most often of urothelial origin with potential for local, locoregional and distant invasion. Among its risk factors, urinary bilharzia is endemic in our study area. The aim of our study was to present the epidemiological, clinical and histopathological aspects of bladder cancer in our department. Patients and method: This was a descriptive cross-sectional study over a 12-month period from January 1 to December 31, 2019. The study took place in the urology department of the university hospital Point “G”. It included all patients hospitalized for bladder cancer. The epidemiological, clinical and histopathological characteristics have been sought and described. Results: A total of 74 patients were included in the study. Bladder cancer was the leading cause of cancer, accounting for 57.9% of all urological cancers. The mean age of the patients was 52.8 ± 16.25 years. A slight male predominance was observed with a sex-ratio of 1.2. Housewives were the most represented with 43.2% followed by farmers with 24.3%. Hematuria was the reason for consultation in 87.8% cases. The main risk factors found were urinary schistosomiasis (48.6%) and smoking (31.1%). These two factors were associated in 23.0% of cases. At diagnosis, 85.7% of patients were classified as T3 or T4 stage. Squamous cell carcinoma with 58.2% was the most common histological type followed by urothelial carcinoma in 26.0% of cases. Conclusion: Bladder cancer is very common of cancer in hospitalized patients in our department. Diagnosis is more often made at an advanced stage. The most common histological type is squamous cell carcinoma.

关键词： Bladder Cancer Epidemiology Clinic Histopathology

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Penile Skin Flap Urethroplasty for Urethral Stenosis at SominéDOLO Hospital of Mopti (MALI)

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Open Journal of Urology 2021年第7期11卷 240-250页

作者： Dramane Cissé honoré jean gabriel berthé Abdoulaye Traoré Mamadou Lamine Diakité Modibo Coulibaly Mory Koné Djibril Traoré Bréhima Traoré Diamilatou Thiam Mamadou Tidiani Coulibaly Alkadri Diarra Amadou Kassogué Moussa Salifou Diallo Oumar Guindo Université des Sciences des Techniques et des Technologies de Bamako Bamako Mali Hô pital Sominé DOLO de Mopti Mopti Mali CHU du Point G Bamako Bamako Mali Direction Régionale de la Santé de Mopti Mopti Mali CHU gabriel TOURE Bamako Bamako Mali CHU Luxembourg Bamako Mali CHU Kati Kati Mali

Introduction: Penile skin flap urethroplasty is a technique for replacing or enlarging an obstructed urethra. We aim to report our experience in the practice of this surgical technique. Patients and method: This was a prospective and descriptive study of penile skin flap urethroplasty indicated for urethral stenosis between January 2014 and December 2019. Results: A total of 21 penile skin flap urethroplasties for urethral stenosis were performed. The average age was 38.6 years old. The stenosis was of sclero-inflammatory origin in 15 cases (71.43%). It was of bulbo-perineal, penile, and penile-bulbar topography in about a third each. A history of urethral surgery was reported in 80.95% of the cases. The average length of the stenosis was 6.8 cm. Mundy circular skin flap urethroplasty about 15 cases (71.43%), and Quartey rectangular skin penile flap urethroplasty about 6 cases (28.57%) were the surgical techniques performed. The postoperative follow-up was favorable in 19 cases (90.48%). Two cases of urethral fistula (9.52%) underwent the 2nd urethroplasty. Urination at 1 year was satisfactory. No relapse has been reported to date. However, 4 patients (19.04%) reported asthenic ejaculation, and 1 patient (4.76%) a marked decrease in sexual pleasure. Conclusion: This surgical technique is effective in terms of voiding when the surgical indications are well chosen. The sexual aspect must be taken into account and the intervention only offered to those who really need it.

关键词： Urethral Stenosis Urethroplasty Pedicled Flap

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It’s not all in your feet: Improving penalty kick performance with humanavatar interaction and machine learning

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The Innovation 2024年第2期5卷 115-121页

作者： jean-Luc Bloechle Julien Audiffren Thibaut Le Naour Andrea Alli Dylan Simoni gabriel Wüthrich jean-Pierre Bresciani Control and Perception Laboratory University of FribourgBd Perolles 901700 FribourgSwitzerland Motion-up Le PrismePlace Albert Einstein56000 VannesFrance FC Basel 1893 Birsstrasse 320A4002 BaselSwitzerland

Penalty kicks are increasingly decisive in major international football ***,over 30%of shootout kicks are *** outcome of the kick often relies on the ability of the penalty taker to exploit anticipatory movements of the goalkeeper to redirect the kick toward the open side of the ***,this ability is difficult to train using classical *** used an augmented reality simulator displaying an holographic goalkeeper to test and train penalty kick performance with 13 young elite *** learning algorithms were used to optimize the learning rate by maintaining an optimal level of training *** training sessions of 20 kicks reduced the redirection threshold by 120 ms,which constituted a 28%reduction with respect to the baseline ***,redirection threshold reduction was observed for all trained players,and all things being equal,it corresponded to an estimated 35%improvement of the success rate.

关键词： kick penalty learning

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Nephroblastoma in Adults about a Clinical Case

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Surgical Science 2024年第2期15卷 81-88页

作者： Tounkara Cheickna Coulibaly Amara Malle Oumar Amadou Bréhima Bolo Coulibaly Bagoyoko Kaloga Daye Samake Hamidou berthe honoré jean-Baptiste gabriel Diakite Mamadou Lamine Department of General Surgery Hospital Center “Mother Child” Luxembourg Bamako Mali Directorate of Army Health Services Kati Mali Department of Urology and Andrology Point G University Hospital Bamako Mali

Nephroblastoma is the most common malignant renal tumor in children and is related to an abnormal proliferation of cells resembling those of the embryonic kidney (metanephroma), hence the terminology;embryonal tumor. These are tumors that remain and remain unstudied in Mali because they are common in adults in our context. Its annual incidence is estimated at approximately 1/10,000 births. Nephroblastoma is a rare or even exceptional tumor in adults. The clinical manifestation was a large swelling of the right hypochondrium;abdominal pain for a year;unquantified fever, hypertension, initial hematuria associated with burning during urination and anemia. The main clinical manifestation remained fever and abdominal pain. This renal tumor posed a diagnostic problem which was previously labeled as a mesenteric tumor in our general surgery department. The diagnosis was made by imaging: CT and magnetic resonance imaging. The treatment is multidisciplinary and combines chemotherapy, surgery with or without radiotherapy. The prognosis is poor due to late diagnosis and less effectiveness of chemotherapy compared to the child. Survival did not exceed a year and a half because the renal tumor in our patient was surgically overcome. We report a case of nephroblastoma in an 86-year-old patient with unfavorable histology (hematogenous metastases), operated on in the general surgery department and whose postoperative course was simple and who was referred to oncology for treatment.

关键词： Nephroblastoma Malignant Kidney Tumor Treatment Adult Mali

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Phenotypical Aspects of a Familial Syndromic Retinitis Pigmentosa

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Open Journal of Ophthalmology 2024年第2期14卷 168-173页

作者： Irma Eneida Dos Santos Joseph Matar Mass Ndiaye Mariama Diambone Badji Alioune Abdoulaye Ndongo Gerauld Akpo jean Pierre Diagne gabriel Karold Mendy Mouhamed Attye Aboubacry Sadikh Sow Elhadji Amadou Ba Paule Aida Ndoye Roth Ophthalmology Department of Aristide Le Dantec Hospital Dakar Senegal Pediatric Department of Aristide Le Dantec Hospital Dakar Senegal Radiological Imaging Department of Aristide Le Dantec Hospital Dakar Senegal Ophthalmology Department of Abass Ndao Hospital Dakar Senegal

Aim: To report a familial case of syndromic retinitis pigmentosa identified at Aristide Le Dantec Hospital in Dakar and to describe their clinical characteristics ophthalmic. Observation: We report a sibling group of nine children, four died at a young age from unknown causes. Three children were affected by retinitis pigmentosa, two cases were syndromic. A history of nyctalopia was found in all three affected children. The mean age of onset of decreased visual acuity was 6.6 years. Patient 1 affected by syndromic retinitis pigmentosa had an extraocular sign of cystic dilation of the main bile duct. Patient 2 had myoclonic epilepsy, psychomotor retardation, and the molar tooth sign on cerebral MRI (highly suggestive of Joubert syndrome). The third child had isolated retinitis pigmentosa. Ophthalmological examinations (fundus examination, electroretinogram, and visual evoked potentials) and pediatric examinations in the remaining two children were normal. Discussion and Conclusion: Retinitis pigmentosa is a rare degenerative disease that can be associated with several other malformations, highlighting the importance of screening for associated conditions. It presents a grim functional prognosis and a life prognosis dependent on extraocular manifestations. Molecular biology (karyotyping, next-generation sequencing) could have identified the implicated genes and allowed for a formal diagnosis and genetic counseling.

关键词： Retinitis Pigmentosa Syndromic Heredity Ciliopathy

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Multiscale Analysis of Semilinear Damped Stochastic Wave Equations

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Acta Mathematica Sinica,English Series 2023年第7期39卷 1305-1331页

作者： Aurelien FOUETIO gabriel NGUETSENG jean Louis WOUKENG Department of Mathematics Higher Teacher Training CollegeUniversity of NgaoundereP.O.Box 652BertouaCameroon Department of Mathematics University of Yaounde IP.O.Box 812YaoundeCameroon Department of Mathematics and Computer Science University of DschangP.O.Box 67DschangCameroon

In this paper we proceed with the multiscale analysis of semilinear damped stochastic wave motions. The analysis is made by combining the well-known sigma convergence method with its stochastic counterpart, associated to some compactness results such as the Prokhorov and Skorokhod theorems. We derive the equivalent model, which is of the same type as the micro-model. One of the novelties of the work is that the corrector problem is solved in the classical sense of distributions,thereby allowing numerical computations of the homogenized coefficients.

关键词： Hyperbolic stochastic equations Wiener Process sigma convergence tightness of probability measures

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Early Prosthetic Valve Endocarditis with Mycobacterium Tuberculosis after Mitral Valve Replacement: A Case Report

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World Journal of Cardiovascular Surgery 2024年第3期14卷 33-40页

作者： Papa Amath Diagne Mory Camara Papa Ousmane Ba Momar Sokhna Diop Moussa Samba Abdou Lahad Mbengue jean Claude Ndiogou Dione Myriam Bizrane Marième Soda Mbaye Moussa Seck Diop Toudiani Malam Kaka Papa Salmane Ba Papa Adama Dieng Amadou gabriel Ciss Assane Ndiaye Cardiovascular and Thoracic Surgery Department FANN National University Hospital Dakar Senegal

Background: Tuberculous endocarditis is a rare but serious complication of heart valve replacement surgery. We report the case of a 24-year-old patient, who presented with tuberculous endocarditis after mechanical mitral valve replacement, with a favorable clinical course following anti-tuberculosis treatment. Case Presentation: We report a 24-year-old male patient, admitted to the cardiac surgery department of the Fann Hospital (Dakar, Senegal), for the management of severe mixed (rheumatic and endocarditic) mitral insufficiency with associated tricuspid insufficiency. He had a history of recurrent angina and polyarthralgia in childhood, was hospitalized several times for refractory global cardiac decompensation, and for a suspected infective endocarditis a month before his admission. On admission, the clinical examination revealed signs suggestive of mitral and tricuspid insufficiency. Transthoracic echocardiography revealed severe post-endocarditic mitral insufficiency with A3 amputation, highly mobile 15 mm vegetations on the free edge of the large valve, moderate tricuspid insufficiency, and severe pulmonary artery hypertension. Mechanical mitral valve replacement and tricuspid valve annuloplasty using autologous pericardial strip were performed via median sternotomy. After ten days, the patient presented with global cardiac decompensation associated with a clinico-biological infectious syndrome, and tans-oesophageal echography revealed an abscess at the sinotubular junction, communicating with the aorta. A thoraco-abdomino-pelvic CT scan was done, which revealed a bilateral alveolar-interstitial syndrome with mediastinal lymphadenopathy. Anti-tuberculosis treatment with RHZE was initiated for 06 months. The clinical course was favorable. Conclusion: Tuberculous endocarditis in prostheses is a serious complication of heart valve replacement surgery, which may evolve favorably under medical treatment.

关键词： Tuberculous Endocarditis Prosthetic Valve Endocarditis Mycobacterium Tuberculosis

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Donation after cardio-circulatory death liver transplantation

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World Journal of Gastroenterology 2012年第33期18卷 4491-4506页

作者： Hieu Le Dinh Arnaud de Roover Abdour Kaba Séverine Lauwick jean Joris jean Delwaide Pierre honoré Michel Meurisse Olivier Detry Department of Abdominal Surgery and Transplantation University Hospital of Liège University of Liège 4000 Liège Belgium Department of Anesthesia and Intensive Care Medicine University Hospital of Liège University of Liège 4000 Liège Belgium Department of Hepatology and Gastroenterol-ogy University Hospital of Liège University of Liège 4000 Liège Belgium

The renewed interest in donation after cardio-circulatory death (DCD) started in the 1990s following the limited success of the transplant community to expand the donation after brain-death (DBD) organ supply and following the request of potential DCD families. Since then, DCD organ procurement and transplantation activities have rapidly expanded, particularly for nonvital organs, like kidneys. In liver transplantation (LT), DCD donors are a valuable organ source that helps to decrease the mortality rate on the waiting lists and to increase the availability of organs for transplantation despite a higher risk of early graft dysfunction, more frequent vascular and ischemia-type biliary lesions, higher rates of re-listing and re-transplantation and lower graft survival, which are obviously due to theinevitable warm ischemia occurring during the declaration of death and organ retrieval process. Experimental strategies intervening in both donors and recipients at different phases of the transplantation process have focused on the attenuation of ischemia-reperfusion injury and already gained encouraging results, and some of them have found their way from pre-clinical success into clinical reality. The future of DCD-LT is promising. Concerted efforts should concentrate on the identification of suitable donors (probably Maastricht category Ⅲ DCD donors), better donor and recipient matching (high risk donors to low risk recipients), use of advanced organ preservation techniques (oxygenated hypothermic machine perfusion, normothermic machine perfusion, venous systemic oxygen persufflation), and pharmacological modulation (probably a multi-factorial biologic modulation strategy) so that DCD liver allografts could be safely utilized and attain equivalent results as DBD-LT.

关键词： Non-heart-beating donation Complication Bile duct Allocation Ischemia Ischemia-reperfusion injury Liver disease

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Advanced list scheduling heuristic for task scheduling with communication contention for parallel embedded systems

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Science China(Information Sciences) 2010年第11期53卷 2272-2286页

作者： NEZAN jean-Francois RAULET Mickaёl COUSIN jean-gabriel IETR/Image and Remote Sensing Group CNRS UMR 6164/INSA Rennes 35043 RENNES Cedex France

Modern embedded systems tend to use multiple cores or processors for processing parallel applications. This paper indeed aims at task scheduling with communication contention for parallel embedded systems and proposes three advanced techniques to improve the list scheduling heuristic. Five groups of node levels (two existing groups and three new groups) are firstly used as node priorities to generate node lists. Then the critical child technique improves the selection of a processor in the scheduling process. Finally, the communication delay technique enlarges the idle time intervals on communication links. We also propose an advanced dynamic list scheduling heuristic by combining the three techniques. Experimental results show that the combined advanced dynamic heuristic is efficient to shorten the schedule length for most of the randomly generated DAGs in the cases of medium and high communication. Our method accelerates an application up to 80% in the case of high communication and can also reduce the use of hardware resources.

关键词： list scheduling communication contention node level critical child communication delay

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Major Elements in Lake Muhazi,Rwanda,East Africa

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Acta Geologica Sinica(English Edition) 2009年第5期83卷 927-931页

作者： jean de la Paix MUPENZI GE Jiwen gabriel HABIYAREMYE China University of Geosciences Institute of Ecology and Environmental Sciences Wuhan 430074 China Hubei Wetland Evolution and Ecological Restoration Key Laboratory Wuhan 430074 China

The aim of this study undertaken at Lake Muhazi in Rwanda was to determine and analyze the major elements present in water. The presence of many major elements （Al, As, Ba, C, Ca, Cu, Fe, H^＋, K, Mg, Mn, N, P, S, Si, and Zn） was determined by spectroscopic technique. The concentrations of the elements were measured in water samples taken from three different locations of the lake from May to August 2008. The lake is polluted by water flow from mountain sides surrounding the lake. Other causes of pollution could be the use of agrochemicals in the sugar land, which surrounds the lake, and human activities near the lake. Finally, we proposed the strategies that can be applied in order to ensure good conservation of the environment and to prevent augmentation of heavy materials into the lake.

关键词： major elements environment spectroscopic technique water pollution Muhazi Lake Rwanda

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