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术前焦虑对肝癌患者麻醉苏醒与术后恢复的影响

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天津医药 2024年第7期52卷 762-765页

作者：朱文智邱倩谭宏宇北京大学肿瘤医院暨北京市肿瘤防治研究所麻醉科恶性肿瘤发病机制及转化研究教育部重点实验室100142

目的探讨术前焦虑对肝脏肿瘤切除手术患者术后苏醒和短期预后的影响。方法选择行择期开腹肝癌切除术的患者96例,美国麻醉师协会(ASA)Ⅰ—Ⅱ级,据汉密尔顿焦虑量表(HAMA)将患者分为对照组41例(HAMA<7分)和焦虑组55例(HAMA≥7分)。记录患... 详细信息

目的探讨术前焦虑对肝脏肿瘤切除手术患者术后苏醒和短期预后的影响。方法选择行择期开腹肝癌切除术的患者96例,美国麻醉师协会(ASA)Ⅰ—Ⅱ级,据汉密尔顿焦虑量表(HAMA)将患者分为对照组41例(HAMA<7分)和焦虑组55例(HAMA≥7分)。记录患者入手术室心率(HR)、平均动脉压(MAP)、手术时间、术中出血量、术中补液量、术中瑞芬太尼消耗量;记录苏醒时间,拔管时间,苏醒期躁动(EA)评分,拔出气管导管后5 min(T_(1)),术后6 h(T_(2))、12 h(T_(3))、24 h(T_(4))、48 h(T_(5))静息及活动疼痛视觉模拟(VAS)评分,以及患者自控静脉镇痛(PCIA)累计有效按压次数、镇痛药物补救情况、术后胃肠道反应情况、术后排气时间、术后5 d血清丙氨酸转氨酶(ALT)与天冬氨酸转氨酶(AST)值和术后住院天数。结果与对照组相比,焦虑组入手术室HR和MAP增高,苏醒时间、拔管时间延长;术中瑞芬太尼消耗量,EA评分,T_(1)、T_(2)、T_(3)静息及活动VAS评分,T_(4)活动VAS评分,PCIA按压次数,镇痛药物补救次数均增加,术后胃肠道反应的发生率升高,术后下床时间、排气时间、进食时间和术后住院天数延长(P<0.05)。结论术前焦虑不利于肝脏肿瘤切除术患者麻醉苏醒和短期预后。

关键词：癌,肝细胞焦虑麻醉苏醒延迟手术后并发症

颈前路椎体次全切融合术中应用3D打印椎体与纳米羟基磷灰石/聚酰胺66椎体的早期临床疗效比较

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中华实验外科杂志 2024年第2期41卷 386-389页

作者：岳玺武金亮杨科荣宋瑞鹏谭洪宇郑州大学第一附属医院骨科郑州450052

目的探讨3D打印椎体与纳米羟基磷灰石/聚酰胺66(n-HA/PA66)椎体对颈前路椎体次全切融合术(ACCF)术后颈椎矢状面影响及早期临床疗效。方法收集2020年6月至2022年1月在郑州大学第一附属医院开展ACCF的患者共56例, 其中应用3D打印椎体(3D组... 详细信息

目的探讨3D打印椎体与纳米羟基磷灰石/聚酰胺66(n-HA/PA66)椎体对颈前路椎体次全切融合术(ACCF)术后颈椎矢状面影响及早期临床疗效。方法收集2020年6月至2022年1月在郑州大学第一附属医院开展ACCF的患者共56例, 其中应用3D打印椎体(3D组)28例, n-HA/PA66椎体(n-HA/PA66组)28例, 比较两组患者术前一般资料, 术后临床和影像学指标。结果 3D组术后3、6、12、18个月C2~7 Cobb高于n-HA/PA66组(19.42±3.20比17.71±2.50、18.71±3.15比17.04±1.94、18.49±3.13比16.86±2.17、18.32±2.89比16.40±1.48, t=-2.233、-2.385、-2.267、-3.121, P<0.05), 3D组术后3、6、12、18个月C2~7 SVA低于n-HA/PA66组(14.52±2.45比16.88±2.50、14.74±2.21比17.30±3.86、14.81±2.28比17.38±3.91、15.27±2.23比17.84±3.76, t=2.595、3.052、3.004、3.107, P<0.05), 3D组术后3、6、12、18个月T1倾斜角高于n-HA/PA66组(24.11±2.88比21.47±2.11、23.15±2.67比20.46±2.02、23.23±2.70比20.64±2.08、22.58±2.44比20.04±2.02, t=-3.912、-4.257、-4.011、-4.253, P<0.05), 3D组术后3个月融合率高于n-HA/PA66组[82.1%(46/56)比65.5%(36/56), χ^(2)=4.004, P<0.05], 3D组术后12、18个月下沉率低于n-HA/PA66组[5.4%(3/56)比21.4%(12/56)、7.1%(4/56)比25.0%(14/56), χ^(2)=6.235、6.619, P<0.05]。结论 3D打印椎体和n-HA/PA66椎体应用于ACCF都可取得良好的早期临床效果, 但3D打印椎体在椎体融合速度、维持生理曲度和减缓沉降方面更具优势。

关键词： 3D打印椎体临床疗效

A Fibonacci View on the Galois NFSR Used in Trivium

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Journal of Systems Science & Complexity 2024年第3期37卷 1326-1350页

作者： WANG hongyu ZHENG Qunxiong QI Wenfeng PLA Strategic Support Force Information Engineering University Zhengzhou 450001China

Trivium is an international standard of lightweight stream ciphers(ISO/IEC 29192-3:2012).In this paper,the Trivium-like NFSRs,a class of Galois NFSRs generalized from the Galois NFSR of Trivium,are studied from the perspective of Fibonacci *** is shown that an n-stage Trivium-like NFSR cannot be equivalent to an n-stage Fibonacci NFSR,which is proved by showing the existence of“collision initial states”.As an intermediate conclusion,a necessary and sufficient condition for a kind of linear degeneracy of a Trivium-like NFSR is obtained from the persepective of interleaved ***,the smallest stage number of a Fibonacci NFSR that can generate all the output sequences of an n-stage Trivium-like NFSR is shown to be greater than n-7 and this value is no less than 371=287+min{93,84,111}specifically for the 288-stage Galois NFSR used in *** results contradict the existence of a equivalent Fibonacci model of Trivium NFSR of small stage,which implies that Trivium algorithm possesses a fair degree of immunity against“structure attack”.

关键词： Fibonacci NFSR galois NFSR interleaved sequence linear degeneracy trivium

SHARP POINTWISE-IN-TIME ERROR ESTIMATE OF L1 SCHEME FOR NONLINEAR SUBDIFFUSION EQUATIONS

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Journal of Computational Mathematics 2024年第3期42卷 662-678页

作者： Dongfang Li hongyu Qin Jiwei Zhang School of Mathematics and Statistics Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory of Engineering Modeling and Scientific Computing Huazhong University of Science and TechnologyWuhan 430074China School of Mathematics and Statistics Wuhan UniversityWuhan 430072China

An essential feature of the subdiffusion equations with theα-order time fractional derivative is the weak singularity at the initial *** weak regularity of the solution is usually characterized by a regularity parameterσ∈(0,1)∪(1,2).Under this general regularity assumption,we present a rigorous analysis for the truncation errors and develop a new tool to obtain the stability results,i.e.,a refined discrete fractional-type Grönwall inequality(DFGI).After that,we obtain the pointwise-in-time error estimate of the widely used L1 scheme for nonlinear subdiffusion *** present results fill the gap on some interesting convergence results of L1 scheme onσ∈(0,α)∪(α,1)∪(1,2].Numerical experiments are provided to demonstrate the effectiveness of our theoretical analysis.

关键词： Sharp pointwise-in-time error estimate Ll scheme Nonlinear subdiffusion equations Non-smooth solutions

A novel evasion guidance for hypersonic morphing vehicle via intelligent maneuver strategy

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Chinese Journal of Aeronautics 2024年第5期37卷 441-461页

作者： Xun LI Xiaogang WANG hongyu ZHOU Yu LI Department of Aerodynamics Harbin Institute of TechnologyHarbin 150001China Beijing Aerospace Technology Institute Beijing 100074China

This paper presents a novel evasion guidance law for hypersonic morphing vehicles,focusing on determining the optimized wing's unfolded angle to promote maneuverability based on an intelligent ***,the pursuit-evasion problem is modeled as a Markov decision *** the agent's action consists of maneuver overload and the unfolded angle of wings,which is different from the conventional evasion guidance designed for fixed-shape *** reward function is formulated to ensure that the miss distances satisfy the prescribed bounds while minimizing energy ***,to maximize the expected cumulative reward,a residual learning method is proposed based on proximal policy optimization,which integrates the optimal evasion for linear cases as the baseline and trains to optimize the performance for nonlinear engagement with multiple ***,offline training guarantees improvement of the constructed evasion guidance law over conventional ***,the guidance law for online implementation includes only analytical *** maps from the confrontation state to the expected angle of attack and the unfolded angle while retaining high computational *** show that the proposed evasion guidance law can utilize the change of unfolded angle to extend the maximum overload *** it surpasses conventional maneuver strategies by ensuring better evasion efficacy and higher energy efficiency.

关键词： Hypersonic vehicles Variable-sweep wings Evasion guidance Reinforcement learning Pursuit-evasion problem

3D打印实物模型在颈椎疾患住院医师规范化培训教学中的应用和探讨

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中国毕业后医学教育 2024年第5期8卷 369-372页

作者：王玉强许建中谭洪宇鲍恒李宇刘会范王秀玲马陶然花卉郑州大学第一附属医院骨科河南郑州450052 郑州大学第一附属医院教育处河南郑州450052

目的探讨3 D打印实物模型在提高颈椎疾患住院医师规范化培训(简称住培)教学效果中的作用。方法选取参加骨科住培的颈椎疾患学习的住院医师80名为研究对象,随机分为两组,观察组(40人)以幻灯讲解加3 D打印实物模型教学,对照组(40人)采用... 详细信息

目的探讨3 D打印实物模型在提高颈椎疾患住院医师规范化培训(简称住培)教学效果中的作用。方法选取参加骨科住培的颈椎疾患学习的住院医师80名为研究对象,随机分为两组,观察组(40人)以幻灯讲解加3 D打印实物模型教学,对照组(40人)采用幻灯讲解教学。课后即时和课后1月分别对住院医师的知识掌握情况和诊疗技术进行现场测试,利用问卷的形式对住院医师的满意度和参与兴趣(10分法)进行调查。结果课后即时观察组的知识掌握情况和对照组相当(P>0.05),但是观察组的诊疗技术测试成绩显著高于对照组(P<0.05),观察组的满意度和参与兴趣评分均显著高于对照组,两者对比差异有统计学意义(均P<0.05);课后1月时,观察组的知识掌握情况和诊疗技术测试成绩均显著高于对照组(均P<0.05)。结论3 D打印实物模型应用于颈椎疾患住培的带教中,可显著提高教学效果,提升住院医师的满意度和参与兴趣,值得在住培教学中推广。

关键词： 3D打印实物模型颈椎教学住院医师规范化培训

Elucidating the enhancement of kaolinite flotation by iron content through density functional theory: A study on sodium oleate adsorption efficiency

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International Journal of Mining Science and Technology 2024年第6期34卷 855-866页

作者： Lingyun Liu Chuilei Kong hongyu Zhao Fangqin Lu Joint National-Local Engineering Research Centre for Safe and Precise Coal Mining Huainan 232001China Department of Materials Science and Engineering Anhui University of Science and TechnologyHuainan 232001China School of Civil and Resource Engineering University of Science and Technology BeijingBeijing 100083China

This study delves into the intricate relationship between iron(Fe)content in kaolinite and its impact on the adsorption behavior of sodium *** effects of different iron concentrations on adsorption energy,hydrogen bond kinetics and adsorption efficiency were studied through simulation and experimental *** results show that the presence of iron in the kaolinite structure significantly improves the adsorption capacity of sodium *** samples with high iron content have better adsorption properties,lower adsorption energy levels and shorter and stronger hydrogen bonds than pure *** optimal concentration of oleic acid ions for achieving maximum adsorption efficiency was identified as 1.2 mmol/L across different kaolinite *** this concentration,the adsorption rates and capacities reach their peak,with Fe-enriched kaolinite samples exhibiting notably higher flotation recovery *** optimal concentration represents a balance between sufficient oleic acid ion availability for surface interactions and the prevention of self-aggregation phenomena that could hinder *** study offers promising avenues for optimizing the flotation process in mineral processing applications.

关键词： Iron Influence Sodium Oleate Adsorption Kaolinite Surfaces Molecular Interaction Analysis Flotation Efficiency Optimization

State Estimation of Drive-by-Wire Chassis Vehicle Based on Dual Unscented Particle Filter Algorithm

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 99-113页

作者： Zixu Wang Chaoning Chen Quan Jiang hongyu Zheng Chuyo Kaku State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130022China Jiangsu Chaoli Electric Co.Ltd. Zhenjiang 212321China

Accurate vehicle dynamic information plays an important role in vehicle driving ***,due to the characteristics of high mobility and multiple controllable degrees of freedom of drive-by-wire chassis vehicles,the current mature application of traditional vehicle state estimation algorithms can not meet the requirements of drive-by-wire chassis vehicle state *** paper proposes a state estimation method for drive-by-wire chassis vehicle based on the dual unscented particle filter algorithm,which make full use of the known advantages of the four-wheel drive torque and steer angle parameters of the drive-by-wire chassis *** the dual unscented particle filter algorithm,two unscented particle filter transfer information to each other,observe the vehicle state information and the tire force parameter information of the four wheels respectively,which reduce the influence of parameter uncertainty and model parameter changes on the estimation accuracy during *** performance with the dual unscented particle filter algorithm,which is analyzed in terms of the time-average square error,is superior of the unscented Kalman filter *** effectiveness of the algorithm is further verified by driving simulator *** this paper,a vehicle state estimator based on dual unscented particle filter algorithm was proposed for the first time to improve the estimation accuracy of vehicle parameters and states.

关键词： Drive-by-wire chassis vehicle Vehicle state estimation Dual unscented particle filter Tire force estimation Unscented particle filter

The Life Cycle of Knowledge in Big Language Models:A Survey

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Machine Intelligence Research 2024年第2期21卷 217-238页

作者： Boxi Cao hongyu Lin Xianpei Han Le Sun Chinese Information Processing Laboratory Beijing 100190China State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 101408China

Knowledge plays a critical role in artificial ***,the extensive success of pre-trained language models(PLMs)has raised significant attention about how knowledge can be acquired,maintained,updated and used by language *** the enormous amount of related studies,there is still a lack of a unified view of how knowledge circulates within language models throughout the learning,tuning,and application processes,which may prevent us from further understanding the connections between current progress or realizing existing *** this survey,we revisit PLMs as knowledge-based systems by dividing the life circle of knowledge in PLMs into five critical periods,and investigating how knowledge circulates when it is built,maintained and *** this end,we systematically review existing studies of each period of the knowledge life cycle,summarize the main challenges and current limitations,and discuss future directions.

关键词： Pre-trained language model knowledge acquisition knowledge representation knowledge probing knowledge editing knowledge application