检索结果-南通市图书馆

Contents of myelin-basic protein and S-100 in serum and brain tissue of neonatal rats with intrauterine infection-caused brain injury

引用

Neural Regeneration Research 2006年第5期1卷 408-411页

作者： Xiaojie Li hongying Li Zhihai Lü Laboratory of Pediatric Neuro-rehabilitation Medical College of Rehabilitation Jiamusi University Jiamusi 154002Heilongjiang Province China Postgraduate of Jiamusi University Jiamusi 154002. Heilongjiang Province China

BACKGROUND： The change of the content of myelin basic protein （MBP） in serum and brain tissue is the biochemical diadynamic index of amyelination. S-100 is a specific and sensitive marker of central nervous system （CNS） injury. Whether or not the content of S-100 and MBP in blood and brain tissue can be used as the quantitative index for early diagnosing the intrauterine infection-caused brain injury still needs investigation. OBJECTIVE ： To observe whether or not MBP and S-100 detection can be used as the biochemical indexes for early diagnosing the intrauterine infection-caused brain injury. DESIGN： Randomized controlled animal experiment. SETTING ： Laboratory of Pediatric Neuro-rehabilitation, Medical College of Rehabilitation, Jiamusi University. MATERIALS ： Sixty female and thirty male common Wistar rats, weighing from 180 to 240 g, were provided by the Experimental Animal Center of Jiamusi University. Reagent： Lipopolysacchande（LPS, serological type 055： B5, SIGMA Company of USA）; MBP enzyme linked immunosobent assay （ELISA） immunoreagent kit （Preclinical Recombination DNA Laboratory, Chengdu Huaxi Medical Center, Sichuan Province）; S-100 ELISA immunoreagent kit （ Department of Physiology, the Fourth Military Medical University of Chinese PLA） and bovine serum albumin（Haitaike Biotechnology Co.,Ltd.）. METHODS ： This experiment was carried out in the Laboratory of Pediatric Neuro-Rehabilitation, Experimental Animal Center, Department of Pathology and Central Laboratory of Jiamusi University from July 2005 to March 2006. ① Preparation of models and grouping： The female and male rats were placed in one cage at 2： 1 at 17：00 o＇clock. Vaginal smear was checked at 8：00 on the next morning. Sperm was found and 0 day of pregnancy was recorded. Pregnant rats were bred in another cage. The pregnant 47 rats were randomly divided into 2 groups： control group （n =10） and experimental group （n =37）. The experimental pregnant rats were intraperitoneally injected wi

关键词： brain injury intrauterine infection electron microscope Experimental Animal biochemical indexes central nervous system inflammatory reaction myelin basic protein bovine serum albumin animal experiment measurement data the differences result analysis animal models Wistar rats

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of ultraviolet irradiation and chlorination on ampicillin-resistant Escherichia coli and its ampicillin resistance gene

引用

Frontiers of Environmental Science & Engineering 2016年第3期10卷 522-530页

作者： Yuchen PANG Jingjing HUANG Jinying XI hongying HU Yun ZHU Environmental Simulation and Pollution Control State Key Joint Laboratory School of Environment Tsinghua University Beijing 100084 China State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC) Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China China Power Engineering Consulting Group Corporation Beijing 100120 China Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China School of Life Sciences Tsinghua University Beijing 100084 China

Antibiotic resistance is a serious public health risk that may spread via potable and reclaimed water. Effective disinfection is important for inactivation of antibiotic-resistant bacteria and disruption of antibiotic resistance genes. Ampicillin is a widely prescribed antibiotic but its effectiveness is increasingly undermined by resistance. In this study, changes in ampicillin resistance for Escherichia coli （E. coli） CGMCC 1.1595 were analyzed after exposure to different doses of ultraviolet （UV） or chlorine, and damage incurred by the plasmid encoding ampicillin resistance gene blaTEM-1 was assessed. We reported a greater stability in ampicillinresistant E. coli CGMCC 1.1595 after UV irradiation or chlorination when compared with previously published data for other E. coli strains. UV irradiation and chlorination led to a shift in the mortality frequency distributions of ampicillin-resistant E. coli when subse-quently exposed to ampicillin. The ampicillin hemiinhibitory concentration （IC5o） without disinfection was 3800mg·L^-1, and an increment was observed after UV irradiation or chlorination. The IC50 of ampicillin-resistant E. coli was 1.5-fold higher at a UV dose of 40 mJ·cm^-2, and was 1.4-fold higher when exposed to 2.0 mg·L^-1 chlorine. These results indicate that UV irradiation and chlorination can potentially increase the risk of selection for E. coli strains with high ampicillin resistance. There was no evident damage to blaTEM-1 after 1-10 mg Cl2· L^-1 chlorination, while a UV dose of 80 mJ·cm^-2 yielded a damage ratio for blaTEM-1 of approximately ***, high UV doses are required for effective disruption of antibiotic resistance genes in bacteria.

关键词： antibiotic resistance Escherichia coli ampicillin resistance gene ultraviolet irradiation chlorination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characteristics of Heavy Minerals and Quantitative Provenance Identification of Sediments from the Muddy Area Outside the Oujiang Estuary Since 5.8 kyr

引用

Journal of Ocean University of China 2018年第6期17卷 1325-1335页

作者： SONG hongying LIU Jinqing YIN Ping ZHANG Yong CHEN Xiaoying Center for Isotope Geochemistry and Geochronology Qingdao National Laboratory for Marine Science and Technology Key Laboratory of Marine Environmental Geology Ministry of Natural Resources Qingdao Institute of Marine Geology Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology College of Earth Science and Engineering Shandong University of Science and Technology

The heavy mineral compositions of the sediments in core D04 with a length of 20.2 m from the muddy area outside the Oujiang Estuary along the coast of Zhejiang-Fujian Provinces have been analyzed. Core D04 can be divided into three units: DU1(0–7.4 m), DU2(7.4–11.4 m) and DU3(11.4–20.2 m). The results showed that the heavy minerals are authigenic pyrite(65.6%)– hornblende(16.0%) – epidote(4.6%) assemblages. The core sediments are mainly composed of clayey silt, which belongs to the clinoform deposit formed since 5.8 kyr, indicating a weak hydrodynamic environment. The deposition rates changed in the trend of high-low-high upward. Quantitative analysis shows that the core sediments were mainly from the suspended sediments of the Changjiang(Yangtze) River, accounting for 79.2%, with only 10.0% from Oujiang, and 10.8% from other provenance. The Oujiang-derived sediments were gradually increased from the bottom unit DU3(3.1%) to the top unit DU1(17.8%), but the Changjiang-derived sediments were gradually decreased. The source changes are closely related to the development of Yangtze River Delta and Wenzhou Bay, climate changes and human activities. During the period of 2.1–3.7 kyr, the sediment supply was greatly reduced due to the poor reclamation capacity of the river basins, resulting in a low deposition rate. Since 2 kyr, the enhancement of human activities in the Yangtze River Basin and the Oujiang River Basin led to more soils to be eroded and transported to the study area. Due to the short distance of the site of core D04 from the Oujiang River mouth, the study area received more Oujiang-derived sediments when upper unit(DU1) deposited than the lower units(DU2 and DU3).

关键词： mud deposit Oujiang Estuary mid-Holocene heavy mineral quantitative identification

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Performance of CMIP6 models in simulating the dynamic sea level:Mean and interannual variance

引用

Atmospheric and Oceanic Science Letters 2023年第1期16卷 34-40页

作者： hongying Chen Zhuoqi He Qiang Xie Wei Zhuang State Key Laboratory of Tropical Oceanography South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhouChina First Institute of Oceanography and Key Laboratory of Marine Science and Numerical ModelingMinistry of Natural ResourcesQingdaoChina Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) GuangzhouChina Institute of Deep-Sea Science and Engineering Chinese Academy of SciencesSanyaChina State Key Laboratory of Marine Environmental Science Xiamen UniversityChina University of Chinese Academy of Sciences BeijingChina

本研究采用卫星测高数据与第六次国际耦合模式比较计划(CMIP6)海平面动力进行对比,重点针对40S-40N地区的动力海平面(DSL),评估了模式对其平均态与年际变率的综合模拟能力,结果表明,对于DSL平均态的模拟,模式与观测结果非常吻合,模式之... 详细信息

本研究采用卫星测高数据与第六次国际耦合模式比较计划(CMIP6)海平面动力进行对比,重点针对40S-40N地区的动力海平面(DSL),评估了模式对其平均态与年际变率的综合模拟能力,结果表明,对于DSL平均态的模拟,模式与观测结果非常吻合,模式之间的差异较小.其中,副热带北大西洋是模拟偏差和模式间差异较为显著的区域,对于DSL年际变率的模拟,模式之间保持较高的一致性,但是,模式与观测结果存在明显差异,模式普遍低估了DSL的年际方差;其中,误差大值区域出现在副热带西边界流附近,模式分辨率会影响CMIP6对中小尺度海洋过程的重现能力,这可能是导致CMIP6历史模拟出现误差的原因之一.

关键词：动力海平面 CMIP6 平均态年际变率模式分辨率

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical study of laser-induced collision process in Eu-Sr in strong field

引用

Science China(Physics,Mechanics & Astronomy) 2005年第1期48卷 78-88页

作者： ZHANG hongying XlAYuanqin CHEN Deying XIAO Pan FAN Rongwei MA Zuguang State Key Laboratory of Tunable Laser Technology Institute of Opto-ElectronicsHarbin Institute of TechnologyHarbin 150001China

Theoretically based on the four-level model,one LICET process in Eu-Sr system in both weak and strong fields was calculated by immediate numerical *** results in weak field are in fair to good agreement with analytical *** results in strong field show that:(a)the peak of the LICET profiles moves to the violet side and the tuning range of the profiles obviously becomes narrower when the laser field intensity increases;and(b)numerical results in strong field differ a lot from analytical ones,which indicates that in strong field,the analytical expressions are not applicable any longer.

关键词： laser-induced collisional energy transfer(LICET) tuning range cross section strong field effect.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Carotid Doppler and transcranial Doppler in diagnosing transient ischemic attack: A healthy control

引用

Neural Regeneration Research 2006年第3期1卷 283-285页

作者： Huiling Chen Jinhua Qiu hongying Liu Department of Neuroelectrophysiology Central People＇s Hospital of Huizhou Huizhou 516001 Guangdong Province China

BACKGROUND： If changes of hemodynamics in internal or external cranial artery and stenosis of atherosclerosis are found eady, patients with transient ischemic attack （TIA） may be treated at an eady phase so as to prevent and decrease the onset of cerebral infarction. Carotid Doppler can analyze carotid canal wall, hemodynamic properties and stenosis, and changes of plaque morphology; however, transcranial Doppler （TCD） can evaluate vascular stenosis and occlusion and judge collateral circulation in cranium through detecting velocity and direction of blood flow. Can the association of them increase the diagnostic rate of TIA？ OB3ECTIVE： To evaluate the effect of the association of carotid Doppler and TCD on TIA in internal carotid artery. DESIGN： Contrast observational study SETTING： Department of Neuroelectrophysiology, Central People＇s Hospital of Huizhou PARTICIPANTS： A total of 54 patients with TIA in internal carotid artery were selected from the Department of Neurology of Huizhou Central People＇s Hospital from May 2004 to June 2005. There were 35 males and 24 females aged 46-81 years. The clinical situation was asthenia of single limb, hemiplegia, anaesthesia of single upper or lower limb, hemianesthesia, sensory disorder and aphasia. The symptoms lasted for less than 2 hours. All cases were diagnosed with CT, and those who had pathological changes of acute cerebral infarction and history of cardiac disease were excluded. Additionally, 50 healthy subjects who were regarded as control group were selected from the Department of Neurology of Huizhou Central People＇s Hospital. There were 30 males and 20 females aged 45-80 years. All subjects were consent. METHODS： HD15000 color Doppler ultrasound （Philips Company, USA） and Muliti-DopX2 TCD （DWL Company, Germany） were used to detect hemodynamics, stenosis and distribution of atherosclerosis in carotid artery and internal carotid artery. Evaluation of marker： Stenosis was calculated by the ratio between the minimal c

关键词： TIA Carotid Doppler and transcranial Doppler in diagnosing transient ischemic attack A healthy control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mode transition induced by gas pressure in dusty acetylene microdischarges: two-dimensional simulation

引用

Plasma Science and Technology 2020年第4期22卷 64-70页

作者： Xiangmei LIU Ningning ZU hongying LI Jingyao LI School of Science Qiqihar UniversityQiqihar 161006People's Republic of China

Radio-frequency microdischarge in acetylene is investigated by use of a fluid model and an aerosol dynamics model in a cylindrical discharge *** this article,the results at a pressure of 100–500 Torr,a voltage of 80–150 V,and an electrode gap of 400–1000μm are carefully analyzed and *** is shown that two electron heating modesαandγappear in the microdischarge,and the pressure-dependent transition fromαtoγwas accompanied by the abrupt decrease of electron density and electron *** mode transition phenomenon is further confirmed by the variation of the electron temperature axial profiles,the profiles vary continuously from a center high at the pressure of 100 Torr to an edge high at the pressure of500 ***,in theαmode(100 Torr)the plasma density increases linearly with the increase of electrode gap,but decreases sharply with the increase of electrode gap in theγmode(>100 Torr).The gas pressure and applied voltage effects on the nanoparticle density and degree of nonuniformity are also *** has been shown that the gas pressure greatly influences the axial profiles of nanoparticle density and the values of the degree of nonuniformity,while the values of the plasma parameters(electron density and nanoparticle density)strongly depend on the applied voltage.

关键词： radio-frequency capacitive discharge acetylene microplasma nanoparticle dynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Systematic functional analysis and potential application of a serine protease from cold-adapted Planococcus bacterium

引用

Food Science and Human Wellness 2023年第5期12卷 1751-1761页

作者： Weijun Leng Xiaoyun Wu Xianghui Qi hongying Liu Li Yuan Ruichang Gao School of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013China Ocean College of Hebei Agriculture University Qinhuangdao 066000China

In this study, a gene encoding serine protease(PmSpr288)from cold-adapted bacterium, namely Planococcus maritimus XJ11, was cloned and overexpressed in Escherichia coli BL21(DE3). Bioinformatics analysis revealed that PmSpr288 belongs to serine protease S8 superfamily with a classical catalytic triad comprised by the Asp49, His86 and Ser251. Moreover, PmSpr288 was found to be active over broad alkaline pH and low-moderate temperature, and exhibited wide range of protein substrate specificity. In addition, PmSpr288 was able to hydrolyze the meat proteins actin and myosin, and molecular docking results suggested that the crucial interaction between PmSpr288 and actin/myosin complexes was mainly occupied by hydrogen bonds. The muscle protein hydrolysates of silver carp prepared by PmSpr288 was shown to have antioxidant activity via DPPH radical scavenging assay, which presented an IC_(50) valve of 1.309 mg/mL. In conclusion, these characteristics imply that PmSpr288 has potential biotechnological application prospect for the production of bioactive peptides.

关键词： Protease Silver carp Protein hydrolysates Molecular docking Bioactive peptides

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Carboniferous ridge subduction in the Xingmeng Orogenic Belt:Constraints from geochronological,geochemical,and Sr-Nd-Hf isotopic analysis of strongly peraluminous granites and gabbro-diorites in the Xilinhot micro-continent

引用

Geoscience Frontiers 2021年第3期12卷 314-332页

作者： Changfeng Liu Zhiguang Zhou Guosheng Wang Chen Wu hongying Li Shiwei Ma School of Ocean Sciences China University of Geosciences(Beijing)Beijing 100083China School of Earth Science and Resources China University of Geosciences(Beijing)Beijing 100083China Key laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau Researchand Center for Excellence in Tibetan Plateau Earth SciencesChinese Academy of SciencesBeijing 100101China Sichuan University of Science&Engineering ZigongSichuan 643002China Beijing No.11 High School Beijing100062 China

The Xingmeng Orogenic Belt evolved through a long-lived orogeny involving multiple episodes of subduction and ***,there is a debate on its tectonic evolution during the Late ***,we report geochemical,geochronological,and isotopic data from strongly peraluminous granites and gabbro-diorites from the Sunidzuoqi-Xilinhot *** U-Pb ages suggest that the intrusive rocks were emplaced during the Early Carboniferous(333-322 Ma).The granites exhibit geochemical characteristics similar to S-type granites,with high SiO_(2)(72.34-76.53 wt.%),Al_(2)O_(3)(12.45-14.65 wt.%),and A/CNK(1.07-1.16),but depleted Sr,Nb,and Ta *** exhibit positiveε_(Nd)(t)andε_(Hf)(t)values(-0.3 to 2.8 and 2.7-5.7,respectively)and young Nd and Hf model ages(T_(DM2)(Nd)=853-1110 Ma and T_(DM2)(Hf)=975-1184 Ma),suggesting that they may be the partial melting products of heterogeneous sources with variable proportions of pelite,psammite,and metabasaltic *** meta-gabbro-diorites from the Maihantaolegai pluton have low SiO_(2)(47.06-53.49 wt.%)and K_2O(0.04-0.99 wt.%)contents,and demonstrate slight light rare earth element(REE)depletion in the chondritenormalized REE *** have high zirconε_(Hf)(t)values(14.41-17.34)and young Hf model ages(T_(DM2)(Hf)=230-418 Ma),indicating a more depleted mantle *** variations of the Sm/Yb and La/Sm ratios can thus be used to assess the melting degree of the mantle source from 5%to 20%,suggesting a quite shallow mantle melting *** propose that the petrogenesis and distribution of the strongly peraluminous granites and gabbro-diorites,as well as the tectonic architecture of the region,can be explained by a ridge subduction *** on these results,and previous studies,we suggest a southward ridge subduction model for the Sunidzuoqi-Xilinhot region.

关键词： Strongly peraluminous granites Gabbro-diorite Xingmeng Orogenic Belt Carboniferous Ridge subduction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Correlation between dominant bacterial community and non-volatile organic compounds during the fermentation of shrimp sauces

引用

Food Science and Human Wellness 2023年第1期12卷 233-241页

作者： Ruichang Gao Huijie Liu Ying Li hongying Liu Yue Zhou Li Yuan School of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013China Ocean College of Hebei Agriculture University Qinghuangdao 066000China

Shrimp sauce,one of the traditional salt-fermented food in China,has a unique flavor that is influenced by the resident *** quality of salt-fermented shrimp sauce was evaluated in this work by determining the total volatile basic nitrogen(TVB-N),the amino acid nitrogen(AAN),organic acid,5’-nucleotide and free amino acids(FAA).Moreover,the dynamics of microbial diversity during processing was investigated by using high-throughput sequencing *** results showed that the AAN,TVB-N,organic acid,5’-nucleotide and FAA content were in range of 0.93-1.42 g/100 mL,49.91-236.27 mg/100 mL,6.65-20.68 mg/mL,3.51-6.56 mg/mL and 81.27-102.90 mg/*** the microbial diversity found in the shrimp sauce,Tetragenococcus,Flavobacterium,Polaribacter,Haematospirillum and Staphylococcus were the predominant *** analysis indicated that the bacteria Tetragenococcus and Staphylococcus were important in the formation of non-volatile *** positively correlated with a variety of FAAs;Staphylococcus positively correlated with 5’-*** analysis indicated that Tetragenococcus and Staphylococcus were the core genera affecting non-volatile *** findings indicate the dynamics of the bacterial community and non-volatile components inter-relationships during shrimp sauce fermentation and provide a theoretical basis for improving the fermentation process of shrimp sauce.

关键词： Shrimp sauces Non-volatile compounds Bacterial community Electronic tongue Correlation analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：