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Recent Advances on Surface-modified Biomaterials Promoting Selective Adhesion and Directional Migration of Cells

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Chinese Journal of Polymer Science 2021年第7期39卷 815-823页

作者： Chen-Xi Tu Chang-you Gao MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China

The surfaces and interfaces of biomaterials interact with the biological systems in multi-scale levels,and thereby influence the biological functions and comprehensive performance in vitro and in *** particular,a surface promoting the selective adhesion and directional migration of desired types of cells in complex environment is extremely important in the repair and regeneration of tissues such as peripheral nerve and blood vessel,and long-term application of intracorporal devices such as intravascular ***,surface modification of biomaterials is a facile and effective method to achieve the desired cell-biomaterials *** this short review,recent advances on the surface modification of biomaterials to regulate selective cell adhesion and migration are briefly *** particular,the surface properties of biomaterials are manipulated via the convenient introduction of amino groups to the ester-based polymers,the formation of polyelectrolyte multilayers,and the fabrication of topology and gradient cues,etc.,followed by the association of chemical and biological signals such as collagen,heparin,hyaluronic acid,peptides and cell growth *** selective adhesion and directional migration of various types of cells such as endothelial cells(ECs),smooth muscle cells(SMCs),hepatocytes and Schwann cells(SCs)are achieved over the competitive counterpart cells by the use of cell-resisting substances and cell-selective motifs on gradient substrates in most *** advances on cell behaviors in three-dimensional(3D)ceH-extracellular matrix(ECM)-mimicking substrates are also reviewed.

关键词： Biomaterials Surface modification Gradient Cell migration Cell selectivity

On China's High-Speed Railway Technology

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第12期12卷 883-884页

作者： you-tong FANG College of Electrical Engineering Zhejiang University Hangzhou 310027 China

Energy and environmental issues have become increasingly prominent in matters of *** with road,air,and sea transportation,railway transportation has the advantages of a large transmission capacity,with rapid,safe,and on-time travel,requiring less land resources,with lower energy consumption,less environmental pollution,and the capacity to operate under most weather *** particular,high-speed railway technology has been growing *** the world's first high-speed railway was built in Japan in 1964,more than ten countries and regions have developed high-speed railways,operating over a total of more than 10000 ***-speed railways not only provide the public with a new type of rapid,convenient,safe,and comfortable travel,but also greatly boost the socio-economic development of the country.

关键词：铁路技术中国铁路运输能源消耗环境问题海上运输传输容量环境污染

Unconventionally anisotropic growth of PbSe nanorods:Controllable fabrication under solution-solid-solid regime over Ag2Se catalysis for broadband photodetection

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Nano Research 2021年第10期14卷 3386-3394页

作者： Su you Li Zhang Qing Yang Hefei National Laboratory of Physical Sciences at the Microscale(HFNL) Department of ChemistryLaboratory of Nanomaterials for Energy Conversion(LNEC)University of Science and Technology of ChinaHefei 230026China

Broadband optoelectronic devices intrigue enormous interests on account of their promising potential in optical communications,sensors and environmental *** nanocrystals are promising candidates for the construction of next-generation photodetectors due to their fascinating intrinsic properties and solution-processed compatibility with varied ***,we report the fabrication of a broadband photodetector on the basis of high-quality solution-processed PbSe nanorods in rock-salt phase grown along unconventionally anisotropic growth direction ofzone *** rock-salt PbSe nanorods are synthesized in solution phase over the catalysis of Ag2Se with relatively high-temperature body-centered cubic phase via a solution-solid-solid growth regime using oleylamine and oleic acid as solvents and stabilizer surfactants,from which the PbSe nanorods with the unconventionally anisotropic growth direction are controllably grown in size and shape in the synthetic procedure typically with about 17 nm in diameter and 58 nm in length on ***,the PbSe nanorods-based photodetector exhibits a broadband response from 405 to 1,064 nm with a high responsivity of 0.78 A·W^(-1)and a fast response time of 17.5μ*** response time is much faster in comparison with most of the PbSe-based photodetectors with response time in millisecond level.

关键词： PbSe nanorod solution-solid-solid(SSS)growth regime superionic conductor catalysis unconventionally anisotropic growth direction near-infrared photodetector broadband photodetection

Assessing artificial neural network performance for predicting interlayer conditions and layer modulus of multi-layered flexible pavement

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Frontiers of Structural and Civil Engineering 2020年第2期14卷 487-500页

作者： Lingyun you Kezhen YAN Nengyuan LIU College of Civil Engineering Hunan UniversityChangsha 410082China Department of Civil and Environmental Engineering Michigan Technological UniversitHoughtonMI 49931USA

The objective of this study is to evaluate the performance of the artificial neural network(ANN)approach for predicting interlayer conditions and layer modulus of a multi-layered flexible pavement *** achieve this goal,two ANN based back-calculation models were proposed to predict the interlayer conditions and layer modulus of the pavement *** corresponding database built with ANSYS based finite element method computations for four types of a structure subjected to flling weight deflectometer *** addition,two proposed ANN models were verifed by comparing the results of ANN models with the results of PADAL and double multiple regression *** measured pavement deflection basin data was used for the *** comparing results concluded that there are no significant differences between the results estimated by ANN and double multiple regression *** modeling results were not accurate due to the inability to reflect the real pavement structure because pavement structure was not completely *** prediction and verification results concluded that the proposed back-calculation model developed with ANN could be used to accurately predict layer modulus and interlayer *** addition,the back-calculation model avoided the back-calculation errors by considering the interlayer condition,which was barely considered by former models reported in the published studies.

关键词： asphalt pavement interlayer conditions finite element method artificial neural network back-calculation

Invariants and Quantum Fluctuations of a Mesoscopic RLC Circuit in a Squeezed State and Squeezed Number State

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Communications in Theoretical Physics 2008年第4期49卷 1052-1054页

作者： YU you-Hong Department of Applied Physics Zhejiang University of Technology Hangzhou 310014 China

The invariants for a mesoscopic RLC circuit with a power source are studied and used to construct the squeezed states and squeezed number states for the system. The quantum fluctuations of the mesoscopic RLC circuit i... 详细信息

关键词： mesoscopic RLC circuit invariant squeezed state

A robust visual SLAM system in dynamic man-made environments

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Science China(Technological Sciences) 2020年第9期63卷 1628-1636页

作者： LIU JiaCheng MENG ZiYang you Zheng Department of Precision Instrument Tsinghua UniversityBeijing 100084China

This paper presents a robust visual simultaneous localization and mapping(SLAM) system that leverages point and structural line features in dynamic man-made environments. Manhanttan world assumption is considered and the structural line features in such man-made environments provide rich geometric constraint, e.g., parallelism. Such a geometric constraint can be therefore used to rectify 3 D maplines after initialization. To cope with dynamic scenarios, the proposed system are divided into four main threads including 2 D dynamic object tracking, visual odometry, local mapping and loop closing. The 2 D tracker is responsible to track the object and capture the moving object in bounding boxes. In such a case, the dynamic background can be excluded and the outlier point and line features can be effectively removed. To parameterize 3 D lines, we use Pl ¨ucker line coordinates in initialization and projection processes, and utilize the orthonormal representation in unconstrained graph optimization process. The proposed system has been evaluated in both benchmark datasets and real-world scenarios, which reveals a more robust performance in most of the experiments compared with the existing state-of-the-art methods.

关键词： SLAM Manhanttan world dynamic scenarios line feature graph optimization

Forward osmosis coupled with lime-soda ash softening for volume minimization of reverse osmosis concentrate and CaCO_(3) recovery: A case study on the coal chemical industry

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Frontiers of Environmental Science & Engineering 2021年第1期15卷 135-144页

作者： Jiandong Lu Shijie you Xiuheng Wang State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China

Reverse osmosis(RO)is frequently used for water reclamation from treated wastewater or desalination *** RO concentrate(ROC)produced from the coal chemical industry(CCI)generally contains refractory organic pollutants and extremely high-concentration inorganic salts with a dissolved solids content of more than 20 g/L contributed by inorganic ions,such as Na^(+),Ca^(2+),Mg^(2+),Cl^(−),and SO_(4)^(2−).To address this issue,in this study,we focused on coupling forward osmosis(FO)with chemical softening(FO-CS)for the volume minimization of CCI ROC and the recovery of valuable resources in the form of CaCO_(3).In the case of the real raw CCI ROC,softening treatment by lime-soda ash was shown to effectively remove Ca^(2+)/Ba^(2+)(>98.5%)and Mg^(2+)/Sr^(2+)/Si(>80%),as well as significantly mitigate membrane scaling during *** softened ROC and raw ROC corresponded to a maximum water recovery of 86%and 54%,*** cyclic FO tests(4×10 h),a 27%decline in the water flux was observed for raw ROC,whereas only 4%was observed for softened *** cleaning efficiency using EDTA was also found to be considerably higher for softened ROC(88.5%)than that for raw ROC(49.0%).In addition,CaCO3(92.2%purity)was recovered from the softening sludge with an average yield of 5.6 kg/m^(3) treated *** study provides a proof-of-concept demonstration of the FO-CS coupling process for ROC volume minimization and valuable resources recovery,which makes the treatment of CCI ROC more efficient and more economical.

关键词： Coal chemical industry Forward osmosis Chemical softening Reverse osmosis concentrate

Facilitation of cascade biocatalysis by artificial multi-enzyme complexes——A review

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Chinese Journal of Chemical Engineering 2020年第11期28卷 2799-2809页

作者： Xinlei Wei Pingping Han Chun you Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin 300308China

Multi-enzyme complexes are the results of natural evolution to facilitate cascade *** enzyme colocalization within a complex,the transfer efficiency of reaction intermediates between adjacent cascade enzymes can be promoted,resulting in enhanced overall reaction *** by nature,a variety of approaches have been developed for the assembly of artificial multi-enzyme complexes with different spatial organizations,aiming at improving the catalytic efficiency of enzyme cascade.A recent trend of this research area is the creation of enzyme complexes with a controllable spatial organization which helps with the mechanistic studies and bears the potential to further increase metabolic *** this review,we summarize versatile strategies for the assembly of artificial multi-enzyme complexes,followed by an inspection of the mechanistic studies of artificial multi-enzyme complexes for their enhancement of catalytic ***,we provide some highlighted in vivo,ex vivo,and in vitro examples that demonstrate the ability of artificial multi-enzyme complexes for enhancing the overall production efficiency of value-added *** research progress has revealed the great biotechnological potential of artificial multi-enzyme complexes as a powerful tool for biomanufacturing.

关键词： Enzyme Biocatalysis Cascade reaction scaffold substrate channeling synthetic biology

Anisotropic magnetocaloric effect in a dysprosium(Ⅲ) single-molecule magnet——Commemorating the 100th anniversary of the birth of Academician Guangxian Xu

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Journal of Rare Earths 2021年第12期39卷 1554-1559,I0004页

作者： you-Song Ding Yan-Zhen Zheng Xi'an Jiaotong University Shenzhen Research Academy Shenzhen 518057China Frontier Institute of Science and Technology Xi'an Jiaotong University

Dysprosium compounds with high magnetic anisotropy are widely studied as single molecule magnets(SMMs).Here the anisotropic magnetocaloric effect in a Dy(Ⅲ)SMM,{[Dy(OSiMe_(3))_(2)(4-Mepy)5(BPh_(4))]0.5 Toluene},was studied by single *** dependent magnetization can be observed at 300 K because of its high magnetic *** behavior measured along the easy axis direction is identical to that of the polycrystalline *** magnetization from the easy axis to the hard plane gives a maximum magnetic entropy change(-ΔSR)of 3.05 J/(kg·K)at 19 K atΔB=5 T,which enables the Dy(Ⅲ)SMM to be used as a low-temperature rotating magnetic refrigerant.

关键词： Lanthanide complex Magnetic anisotropy Rotate magnetocaloric effect Single molecule magnets Rare earths