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Toward Intelligent Financial Advisors for Identifying Potential Clients:A Multitask Perspective

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Big Data Mining and Analytics 2022年第1期5卷 64-78页

作者： Qixiang Shao Runlong Yu Hongke Zhao Chunli Liu Mengyi Zhang Hongmei Song Qi Liu Department of Anhui Province Key Laboratory of Big Data Analysis and Application(BDAA) School of Computer Science and TechnologyUniversity of Science and Technology of China Department of College of Management and Economics Tianjin University School of Management Hefei University of Technology Department of Information Technology China Merchants Bank

Intelligent Financial Advisors(IFAs)in online financial applications(apps)have brought new life to personal investment by providing appropriate and high-quality portfolios for users.In real-world scenarios,identifying potential clients is a crucial issue for IFAs,i.e.,identifying users who are willing to purchase the portfolios.Thus,extracting useful information from various characteristics of users and further predicting their purchase inclination are urgent.However,two critical problems encountered in real practice make this prediction task challenging,i.e.,sample selection bias and data sparsity.In this study,we formalize a potential conversion relationship,i.e.,user→activated user→client and decompose this relationship into three related tasks.Then,we propose a Multitask Feature Extraction Model(MFEM),which can leverage useful information contained in these related tasks and learn them jointly,thereby solving the two problems simultaneously.In addition,we design a two-stage feature selection algorithm to select highly relevant user features efficiently and accurately from an incredibly huge number of user feature fields.Finally,we conduct extensive experiments on a real-world dataset provided by a famous fintech bank.Experimental results clearly demonstrate the effectiveness of MFEM.

关键词： Intelligent Financial Advisor(IFA) potential client identification MultiTask Learning(MTL) feature selection

Intercellular adhesion molecule-1 expression in the hippocampal CA1 region of hyperlipidemic rats with chronic cerebral ischemia

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Neural Regeneration Research 2012年第17期7卷 1312-1317页

作者： Yingying Cheng Ying Zhang Hongmei Song Jiachun Feng Department of Neurology The First Bethune Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

Chronic cerebral ischemia is a pathological process in many cerebrovascular diseases and it is induced by long-term hypedipidemia, hypertension and diabetes mellitus. After being fed a high-fat diet for 4 weeks, rats were subjected to permanent occlusion of bilateral common carotid arteries to establish rat models of chronic cerebral ischemia with hypedipiclemia. Intercellular adhesion molecule-1 expression in rat hippocampal CA1 region was determined to better understand the mechanism underlying the effects of hypedipidemia on chronic cerebral ischemia. Water maze test results showed that the cognitive function of rats with hyperlipidemia or chronic cerebral ischemia, particulady in rats with hypedipidemia combined with chronic cerebral ischemia, gradually decreased between 1 and 4 months after occlusion of the bilateral common carotid arteries. This correlated with pathological changes in the hippocampal CA1 region as detected by hematoxylin-eosin staining. Immunohistochemical staining showed that intercellular adhesion molecule-1 expression in the hippocampal CA1 region was noticeably increased in rats with hyperlipidemia or chronic cerebral ischemia, in particular in rats with hyperlipidemia combined with chronic cerebral ischemia. These findings suggest that hyperlipidemia aggravates chronic cerebral ischemia-induced neurological damage and cognitive impairment in the rat hippocampal CA1 region which may be mediated, at least in part, by up-regulated expression of intercellular adhesion molecule-l.

关键词： hyperlipidemia chronic cerebral ischemia intercellular adhesion molecule-I hippocampus CA1 water maze test cognitive function neural regeneration

Experimental and numerical study on ignition and combustion characteristics of boron-magnesium composite powders

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Particuology 2024年第1期84卷 12-29页

作者： Shuyuan Liu Luyang Han hongmei Liu Yingkai song Linlin Liu songqi Hu Science and Technology on Combustion Internal Flow and Thermo-Structure LaboratoryNorthwestern Polytechnical UniversityXi'an710072China School of Mechanical Engineering and Rail Transit Changzhou UniversityChangzhou213164China Shanghai Institute of Space Propulsion Shanghai201112China Shanghai Engineering Research Center of Space Engine Shanghai201112China

A high-pressure laser ignition and combustion system with adjustable oxidizer gas atmosphere is established to investigate the ignition and combustion characteristics of boron-magnesium(BM)com-posite powders.An ignition and combustion model of BM powders is established and validated in the present study.The results show that increasing water content,O_(2) content and Mg content all result in shorter ignition delay time of BM powders,among which the effect of water content is the most obvious.However,ignition delay time increases as pressure increases.The combustion time decreases with increasing Mg content and ambient pressure but increases with water content.With the increase of O_(2) content,combustion time of BM powders first increases and then decreases,which means a critical O_(2) content exists above which combustion time decreases.The results show that there exists a trade-off between ignition and combustion performance of BM composite powders.

关键词： Boron magnesium powder Laser ignition Ignition and combustion model Reaction mechanism Numerical model

Tailoring Practically Accessible Polymer/Inorganic Composite Electrolytes for All-Solid-State Lithium Metal Batteries:A Review

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Nano-Micro Letters 2023年第3期15卷 266-297页

作者： hongmei Liang Li Wang Aiping Wang Youzhi song Yanzhou Wu Yang Yang Xiangming He Institute of Nuclear and New Energy Technology Tsinghua UniversityBeijing 100084People’s Republic of China

Solid-state electrolytes(SSEs)are widely considered the essential components for upcoming rechargeable lithium-ion batteries owing to the potential for great safety and energy density.Among them,polymer solid-state electrolytes(PSEs)are competitive candidates for replacing commercial liquid electrolytes due to their flexibility,shape versatility and easy machinability.Despite the rapid development of PSEs,their practical application still faces obstacles including poor ionic conductivity,narrow electrochemical stable window and inferior mechanical strength.Polymer/inorganic composite electrolytes(PIEs)formed by adding ceramic fillers in PSEs merge the benefits of PSEs and inorganic solid-state electrolytes(ISEs),exhibiting appreciable comprehensive properties due to the abundant interfaces with unique characteristics.Some PIEs are highly compatible with high-voltage cathode and lithium metal anode,which offer desirable access to obtaining lithium metal batteries with high energy density.This review elucidates the current issues and recent advances in PIEs.The performance of PIEs was remarkably influenced by the characteristics of the fillers including type,content,morphology,arrangement and surface groups.We focus on the molecular interaction between different components in the composite environment for designing high-performance PIEs.Finally,the obstacles and opportunities for creating high-performance PIEs are outlined.This review aims to provide some theoretical guidance and direction for the development of PIEs.

关键词： Polymer Inorganic composite electrolytes All-solid-state lithium metal batteries Fillers Ionic conductivity High voltage

The role of intraoperative neurophysiological monitoring in intramedullary spinal cord tumor surgery

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Chinese Neurosurgical Journal 2024年第1期10卷 57-66页

作者： Kai Liu Chengyuan Ma Dapeng Li Haisong Li Xuechao Dong Bo Liu Ying Yu Yuxiang Fan Hongmei Song Department of Neurosurgery Bethune First Hospital of Jilin UniversityChangchunJilinChina

Intramedullary tumors are a class of central nervous system tumors with an incidence of 2 to 4%.As they are located very deep and frequently cause postoperative neurological complications,surgical resection is difficult.In recent years,many surgeons have performed electrophysiological monitoring to effectively reduce the occurrence of post-operative neurological complications.Modern electrophysiological monitoring technology has advanced considerably,leading to the development of many monitoring methods,such as SSEPs,MEPs,DCM,and EMG,to monitor intramedullary tumors.However,electrophysiological monitoring in tumor resection is still being studied.In this article,we discussed the different monitoring methods and their role in monitoring intramedullary tumors by reviewing previous studies.Intratumorally tumors need to be monitored for a summary of the condition of the patient.Only by using various monitoring methods flexibly and through clear communication between surgeons and neurophysiological experts can good decisions be made during surgery and positive surgical results be achieved.

关键词： Intramedullary spinal cord tumor Intraoperative neurophysiological monitoring D-wave

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特异性抗体检测的临床意义

中华儿科杂志 2020年第4期58卷 343-345页

作者：宋红梅中国医学科学院北京协和医学院北京协和医院儿科 100730

特异性抗体也称为免疫球蛋白,是介导体液免疫应答的重要效应分子,在抗感染免疫过程中起着非常重要的作用,也是临床上感染性疾病诊断和治疗的重要依据。了解特异性抗体的产生、生物特性以及不同病原体特异性抗体之间的差别等相关知识,对... 详细信息

特异性抗体也称为免疫球蛋白,是介导体液免疫应答的重要效应分子,在抗感染免疫过程中起着非常重要的作用,也是临床上感染性疾病诊断和治疗的重要依据。了解特异性抗体的产生、生物特性以及不同病原体特异性抗体之间的差别等相关知识,对相关疾病的诊治有重要的临床指导意义。本文将简要介绍在临床工作中经常用到的、以及常见几种感染相关疾病抗体的基本知识点,希望对大家的临床工作有所帮助。

关键词：体液免疫应答抗感染免疫免疫球蛋白生物特性临床指导意义特异性抗体效应分子基本知识点

感染和免疫中的中庸之道:认识疾病耐受的概念

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中华儿科杂志 2020年第12期58卷 963-965页

作者：宋红梅中国医学科学院北京协和医学院北京协和医院儿科100730

疾病耐受是指在不减少病原载量的情况下,通过适宜的反应使机体保持健康状态。这是一种独特的防御策略,其机制涉及免疫适宜、免疫代谢等方面。面对感染,是“和平共生”还是“顽强抵抗”,要找寻其中的“中庸之道”。

关键词：防御策略中庸之道载量免疫健康状态顽强抵抗耐受感染

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关注原发性免疫缺陷病患儿的生活质量

中华儿科杂志 2019年第12期57卷 905-908页

作者：宋红梅中国医学科学院北京协和医学院北京协和医院儿科100730

原发性免疫缺陷病(PID)是由于先天性免疫器官、细胞和分子等缺陷导致的一组临床综合征,目前分为9大类共354种疾病.近年来PID患儿的生存率有了明显提高,关注和改善这些患儿的生活质量是对儿童免疫科医生提出的新任务和挑战.早期识别、及... 详细信息

原发性免疫缺陷病(PID)是由于先天性免疫器官、细胞和分子等缺陷导致的一组临床综合征,目前分为9大类共354种疾病.近年来PID患儿的生存率有了明显提高,关注和改善这些患儿的生活质量是对儿童免疫科医生提出的新任务和挑战.早期识别、及时诊断是第一步;其次是选择适当的治疗方法,尽早骨髓移植是治疗重症联合免疫缺陷病的关键;再者,对可药物治疗的PID患儿进行正确规范的药物治疗及预防感染等对症和支持措施也同样重要.

关键词：原发性免疫缺陷病临床综合征免疫科骨髓移植先天性免疫早期识别及时诊断重症联合免疫缺陷病

Hemispherectomy for symptomatic hemiconvulsion-hemiplegia-epilepsy:A case report

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Neural Regeneration Research 2011年第17期6卷 1342-1345页

作者： Yunqian Li Lichao Sun Hongmei Song Jiqing Qiu Department of Neurosurgery First Hospital of Jilin University Changchun 130021 Jilin Province China Epilepsy Center Department of Neurology First Hospital of Jilin University Changchun 130021 Jilin Province China

We described a case of hemiconvulsion-hemiplegia-epilepsy syndrome treated by anatomical hemispherectomy. A 9-year-old boy who suffered from frequent convulsions at 1 month old, left hemiparesis, free of fever, followed by epileptic seizure at 4 years of age, and was diagnosed with hemiconvulsion-hemiplegia-epilepsy syndrome. Clinical manifestations and Wada test results confirmed that the impaired function of the affected cerebral hemisphere had been compensated by the normal hemisphere. The patient was treated by anatomic hemispherectomy. After the operation, the patient was seizure-free, but did not take any anti-epileptic drugs, and the hemiplegia was not aggravated. These findings demonstrated that the cortex controlling sensory and motor function has transferred.

关键词： hemispherectomy epilepsy hemiplegia