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Majid conjecture: quantum Kac-Moody algebras version

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Frontiers of Mathematics in China 2021年第3期16卷 727-747页

作者： hongmei hu Naihong hu Limeng XIA School of Mathematical Sciences Suzhou University of Science and TechnologyShihu CampusSuzhou215009China School of Mathematical Sciences Shanghai Key Laboratory of PMMPEast China Normal UniversityMinhang CampusShanghai200241China Institute of Applied System Analysis Jiangsu UniversityZhenjiang212013China

Based on the n-fold tensor product version of the generalized double-bosonization construction,we prove the Majid conjecture of the quantum Kac-Moody algebras ***,we give explicitly the double-bosonization type-crossing constructions of quantum Kac-Moody algebras for affine types G(1)2,E(1)6,and Tp,q,r,and in this way,we can recover generators of quantum Kac-Moody algebras with braided groups defined by R-matrices in the related braided tensor *** gives us a better understanding for the algebra structures themselves of the quantum Kac-Moody algebras as a certain extension of module-algebras/module-coalgebras with respect to the related quantum subalgebras of finite types inside.

关键词： Double-bosonization quantum Kac-Moody algebras R-matrix

Speech Enhancement via Residual Dense Generative Adversarial Network

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Computer Systems Science & Engineering 2021年第9期38卷 279-289页

作者： Lin Zhou Qiuyue Zhong Tianyi Wang Siyuan Lu hongmei hu School of Information Science and Engineering Southeast UniversityNanjing210096China Medizinische Physik and Cluster of Excellence“Hearing4all” Department of Medical Physics and AcousticsUniversity of Oldenburg26129OldenburgGermany

Generative adversarial networks(GANs)are paid more attention to dealing with the end-to-end speech enhancement in recent *** GANbased enhancement methods are presented to improve the quality of reconstructed ***,the performance of these GAN-based methods is worse than those of masking-based *** tackle this problem,we propose speech enhancement method with a residual dense generative adversarial network(RDGAN)contributing to map the log-power spectrum(LPS)of degraded speech to the clean *** detail,a residual dense block(RDB)architecture is designed to better estimate the LPS of clean speech,which can extract rich local features of LPS through densely connected convolution ***,sequential RDB connections are incorporated on various scales of *** significantly increases the feature learning flexibility and robustness in the time-frequency *** show that the proposed method achieves attractive speech enhancement performance in various acoustic ***,in the untrained acoustic test with limited priors,e.g.,unmatched signal-to-noise ratio(SNR)and unmatched noise category,RDGAN can still outperform the existing GAN-based methods and masking-based method in the measures of PESQ and other evaluation *** indicates that our method is more generalized in untrained conditions.

关键词： Generative adversarial networks neural networks residual dense block speech enhancement

Effect of myosin heavy chain composition of muscles on meat quality in Laiwu pigs and Duroc

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Science China(Life Sciences) 2008年第2期51卷 127-132页

作者： hu hongmei, WANG JiYing, Zhu RongSheng, GUO JianFeng & WU Ying Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China Institute of Animal Science and Veterinary Medicine Shandong Academy of Agricultural Sciences Jinan China

In order to explain the mechanism of high meat quality in Laiwu pigs and investigate the relation between myosin heavy chains (MyHC) composition and meat quality, meat quality analysis was conducted and mRNA expression of MyHC I, IIa, IIx, IIb was quantified by real-time fluorescence PCR in longissimus muscle (LM) and semimembranous muscle of Laiwu pigs and Duroc. The result indicated that, compared with Duroc, mRNA expression of MyHC IIa, IIx in LM and semimembranous muscle of Laiwu pigs was significantly increased, mRNA expression of MyHC IIb was dramatically decreased. However, the expression of MyHC I was not significantly affected by breeds. The correlation between mRNA expression of MyHC I, IIa, IIx in LM and meat color, pH value, marbling, intramuscular fat content was positive, but shear value of LM was negative. The relation between MyHC IIb mRNA expression and marbling, intramuscular fat content was dramatically negative, whereas shear value was strikingly positive, as well as fiber diameter, but without reaching statistical significance. Therefore, the composition of MyHC I, IIa, IIx, IIb affected meat quality, furthermore, expression of MyHC I, IIa, IIx, IIb mRNA prominently influenced meat characteristics, especially edible quality of muscle, suggesting that mRNA expression level of MyHC I, IIa, IIx, IIb can exactly and impersonally estimate meat quality.

关键词： Laiwu pigs myosin heavy chain real-time PCR meat quality

影响地下隧道衬砌混凝土抗蚀性因素的优化设计(英文)

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硅酸盐学报 2008年第1期36卷 99-104页

作者：胡红梅马保国钱刚厦门大学建筑与土木工程学院福建厦门361005 武汉理工大学材料学院武汉430070 厦门东通道工程现场指挥部总监办福建厦门361009

从提高混凝土本体的密实性与防腐能力和维持钢筋钝化性能的化学环境出发,对影响地下隧道衬砌混凝土抗蚀性的主要因素进行了研究。通过对胶凝材料组分与颗粒级配、高效减水剂与新型高效钢筋阻锈剂进行优化设计,实现了对水化产物相和界面... 详细信息

从提高混凝土本体的密实性与防腐能力和维持钢筋钝化性能的化学环境出发,对影响地下隧道衬砌混凝土抗蚀性的主要因素进行了研究。通过对胶凝材料组分与颗粒级配、高效减水剂与新型高效钢筋阻锈剂进行优化设计,实现了对水化产物相和界面结构的调控与优化。研究结果表明:地下隧道衬砌混凝土的优化配比为5%～10%(质量分数,下同)硅灰与30%～40%大掺量粉煤灰复合内掺,1.30%萘系或1.25%聚羧酸系高效减水剂与8%还原铁粉或0.05%D–葡萄糖酸钠阻锈剂复合外掺,该多元组分混凝土满足抗渗等级>P20,氯离子扩散系数DRCM0.80的高防水抗蚀要求。

关键词：地下隧道衬砌混凝土抗蚀性优化设计

Deposition Pattern of Inosine Monophosphate( IMP) in Pig Muscle during Cold Storage

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Animal husbandry and Feed Science 2017年第4期9卷 197-199,218页

作者： Zhu Rongsheng Wang huaizhong Lin Song Wang Yanping hu hongmei Institute of Animal husbandry and Veterinary Medicine Shandong Academy of Agricultural Sciences/Shandong Provincial Key Laboratory of Disease Control and Animal Breeding

[ Objective] The paper was to investigate the degradation and deposition changes of inosine monophosphate （IMP） and its metabolites in muscle of lean pigs and crossbreeding pigs under cold storage condition at 4℃. [ Method] The contents of IMP and its metabolites in longissimus dorsi of lean pigs and crossbreeding pigs were determined by HPLC method. [ Result] Duroc, Landrace, Yorkshire and DLY pigs shared the same degradation and deposition pattern on IMP, inosine and hypoxanthine. On the second day of cold storage, the content of IMP reached the maximum value, which increased by 0.4% - 15.32% compared with the first day, and then it started to decline. On the fourth day of cold storage, the content of IMP significantly reduced by 23.81% - 39.06% than that on the second day. On the fifth and sixth day of cold storage, the content of IMP kept on falling down slowly and maintained around 1.0 mg/g. While the contents of inosine and hypoxanthine showed an increasing tendency with the extension of cold storage time. [ Conclusion ] Lean pigs Duroc, Landraee and Yorkshire and DLY three- way crossbreeding pigs shared the same degradation and deposition pattern on IMP and its metabolites. With the extension of cold storage, the content of IMP first increased then gradually decreased; while inosine and hypoxanthine gradually increased, and the difference among breeds was not significant.

关键词： Pig muscle IMP Inosine Hypoxanthine Deposition pattern

Comparative research on the mechanical property and precipitation of the 2101 and 2205 duplex stainless steels

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Baosteel Technical Research 2010年第2期4卷 54-58页

作者： ZHANG Wei JIANG Laizhu SONG hongmei hu Jincheng WANG Zhiyu Stainless Steel Technology Center Research Institute Baoshan Iron ＆ Steel Co. Ltd. Shanghai 200431 China

The mechanical property and precipitation of the 2101 and 2205 duplex stainless steels were investigated. The results show that with nitrogen-content increasing from 0.12% to 0.26% to partly replace nickel ,the yield strength of the 2101 steel gains an increase of 80 MPa whilst its elongation proportion keeps unchanged. The impact energy at a low temperature is obviously reduced. The temperature at which the impact energy starts decreasing is lower than 20℃, -20℃ and - 40℃ for the 2101 steels containing 0.5 % Ni, 1.5 % Ni and 2.5 % Ni respectively, whereas it is - 70℃ for the 5 % Ni- containing 2205 steel. The nose temperature of precipitation is 700℃ for the 2101 steel and 850℃ for the 2205 steel. The scanning electronic microscope （SEM） ,the transmission electron microscope （TEM） and the X-ray diffraction （XRD） analyses show that the drop in the impact energy of the 2101 steel can be mainly attributed to the precipitation of Cr2N upon ageing while it is attributed to the sigma phase for the 2205 steel.

关键词： duplex stainless steel : impact energy ageing precipitation

Genetic architecture of maize yield traits dissected by QTL mapping and GWAS in maize

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The Crop Journal 2022年第2期10卷 436-446页

作者： Xiao Zhang Zhiyong Ren Bowen Luo Haixu Zhong Peng Ma Hongkai Zhang hongmei hu Yikai Wang Haiying Zhang Dan Liu Ling Wu Zhi Nie Yonghui Zhu Wenzhu He Suzhi Zhang Shunzong Su Yaou Shen Shibin Gao Maize Research Institute Sichuan Agricultural UniversityChengdu 611130SichuanChina Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region Ministry of AgricultureChengdu 611130SichuanChina Guangxi Qingqing Agricultural Technology CO. LTD.Nanning 530000GuangxiChina Biotechnology and Nuclear Technology Research Institute Sichuan Academy of Agricultural SciencesChengdu 610066SichuanChina Crop Research Institute Sichuan Academy of Agricultural SciencesChengdu 610066SichuanChina State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Chengdu 611130SichuanChina g College of Agronomy Sichuan Agricultural UniversityChengdu 611130SichuanChina

The study of yield traits can reveal the genetic architecture of grain yield for improving maize *** this study, an association panel comprising 362 inbred lines and a recombinant inbred line population derived from X178 × 9782 were used to identify candidate genes for nine yield traits. High-priority overlap(HPO) genes, which are genes prioritized in a genome-wide association study(GWAS), were investigated using coexpression networks. The GWAS identified 51 environmentally stable SNPs in two environments and 36 pleiotropic SNPs, including three SNPs with both attributes. Seven hotspots containing 41 trait-associated SNPs were identified on six chromosomes by permutation. Pyramiding of superior alleles showed a highly positive effect on all traits, and the phenotypic values of ear diameter and ear weight consistently corresponded with the number of superior alleles in tropical and temperate germplasm. A total of 61 HPO genes were detected after trait-associated SNPs were combined with the coexpression networks. Linkage mapping identified 16 environmentally stable and 16 pleiotropic *** SNPs that were located in QTL intervals were assigned as consensus SNPs for the yield *** the candidate genes predicted by our study, some genes were confirmed to function in seed development. The gene Zm00001 d016656 encoding a serine/threonine protein kinase was associated with five different traits across multiple environments. Some genes were uniquely expressed in specific tissues and at certain stages of seed development. These findings will provide genetic information and resources for molecular breeding of maize grain yield.

关键词： Maize Yield traits Genome-wide association study(GWAS) Quantitative trait locus(QTL) Coexpression networks

鼓浪屿历史风貌建筑砂浆退化现状分析及修复技术探讨

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材料导报 2021年第2期35卷 2026-2031页

作者：胡红梅刘涛吴琪昕厦门大学建筑与土木工程学院厦门361005

通过实地调研与取样,研究分析鼓浪屿历史风貌建筑砂浆的现状与性能退化原因。结果表明:鼓浪屿历史风貌建筑多由石灰基砂浆砌筑而成,其中大部分为石灰黏土混合砂浆,少部分为石灰砂浆,现已普遍出现开裂、发霉发黑、渗水、风化剥落等严重... 详细信息

通过实地调研与取样,研究分析鼓浪屿历史风貌建筑砂浆的现状与性能退化原因。结果表明:鼓浪屿历史风貌建筑多由石灰基砂浆砌筑而成,其中大部分为石灰黏土混合砂浆,少部分为石灰砂浆,现已普遍出现开裂、发霉发黑、渗水、风化剥落等严重退化。长期遭受海风、盐雾的侵蚀和高温、高湿等多种破坏因素的交互作用是加剧石灰基砂浆性能退化的外部原因,且距离海岸线越近,破坏越严重。而石灰的气硬性属性和石灰与黏土、石英砂之间的低火山灰反应程度,是导致石灰基砂浆自身强度及其与砌体之间的粘结强度低且耐久性差的内在原因。基于“原材料、原工艺,最小干预”的古建筑修复原则,提出在传统壳灰砂浆中加入活性硅铝质材料,通过改性技术将气硬性壳灰转变为同时兼具水硬性与气硬性的改性壳灰,用改性壳灰砂浆置换退化砂浆的砌体结构置换补强修复技术。

关键词：鼓浪屿历史风貌建筑砂浆退化修复

Demethylzeylasteral induces PD-L1 ubiquitin-proteasome degradation and promotes antitumor immunity via targeting USP22

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Acta Pharmaceutica Sinica B 2024年第10期14卷 4312-4328页

作者： Yanyan Zhang Yun huang Dianping Yu Mengting Xu hongmei hu Qing Zhang Minchen Cai Xiangxin Geng Hongwei Zhang Jianhua Xia Mengmeng Guo Dong Lu Hanchi Xu Linyang Li Xing Zhang Qun Wang Sanhong Liu Weidong Zhang Shanghai Frontiers Science Center of TCM Chemical Biology Institute of Interdisciplinary Integrative Medicine ResearchShanghai University of Traditional Chinese MedicineShanghai 201203China Department of Phytochemistry School of PharmacySecond Military Medical UniversityShanghai 200433China Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100193China The Research Center for Traditional Chinese Medicine Shanghai Institute of Infectious Diseases and BiosafetyInstitute of Interdisciplinary Integrative Medicine ResearchShanghai University of Traditional Chinese MedicineShanghai 201203China

Programmed cell death ligand-1(PD-L1)is a T cell inhibitory immune checkpoint molecule that interacts with programmed cell death-1(PD-1)to promote immune escape of tumor *** with antibody therapies,small molecule drugs show better prospects due to their advantages such as higher bioavailability,better tissue penetration,and reduced risk of ***,we found that the small molecule demethylzeylasteral(Dem)can significantly downregulate the expression of PD-L1 in colorectal cancer cells and enhance the killing effect of T cells on tumor ***,Dem binds to the deubiquitinating enzyme USP22 and promotes its degradation,resulting in increased ubiquitination and degradation of PD-L1 through the proteasome *** addition,Dem increased the activity of cytotoxic T cells and reduced the number of myeloid-derived suppressor cells(MDSCs)and regulatory T cells(Tregs)in tumor-infiltrating lymphocytes(TILs),thereby activating the tumor immune microenvironment and inhibiting the growth of subcutaneous MC38 tumors in C57BL/6 ***,we also found that the combination of Dem and CTLA4 antibodies can further improve the efficacy of antitumor *** study reveals the mechanism by which Dem promotes PD-L1 degradation and suggests that the combination of Dem and CTLA4 antibodies may improve the efficacy of immunotherapy.

关键词： Demethylzeylasteral PD-L1 USP22 Deubiquitination Tumor-infiltrating lymphocytes Colorectal cancer Immune checkpoint blockade Antitumor immunity