检索结果-南通市图书馆

High prevalence of pathogenic Leptospira in wild and domesticated animals in an endemic area of China

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 841-845页

作者： Wang Yalin Zeng Lingbing yang hongliang Xu Jianmin Zhang Xiangyan Guo Xiaokui Pal Utpal Qin Jinhong Department of Medical Microbiology and Parasitology Institutes of Medical SciencesShanghai Jiao Tong University School of Medicine Department of Microbiology Immunology and PathologyColorado State UniversityFort CollinsCOUSA 80526 Jiangxi Provincial Center for Disease Control and Prevention Department of Veterinary Medicine University of MarylandCollege ParkMaryland20742USA

Objective:To assess the prevalence of Leptospira detected in wildlife and domesticated animals in Jiangxi Province,China,in ***:Urine samples from 28 buffaloes and kidney samples from 50 pigs,50 dogs and 38 rats were collected from Fuliang and Shangrao County,Jiangxi Province,China,in October *** chain reaction(PCR) and culture analyses were used to detect *** cultured isolates were typed using the microscopic agglutination lest(MAT).Results:The results showed that rats potentially serve as the main reservoir of leptospiral infection,followed by *** 16%of rats(6/38) were positive using culture analysis,PCR analysis using the diagnostic primers G1/G2 and B64Ⅰ/B64Ⅱor lipLS2 showed identification as 50%and 24%,respectively,of the rat samples as positive for the presence of leptospiral ***:PCR-based detection of leptospiral DNA in infected kidney tissues of reservoirs is more efficient when using G1/G2 primers than lipL32 primers. However,the latter primers have a potential application for detection in urine *** alarmingly high prevalence of leptospiral DMA in the wild rat population near human habitation underscores the utility of routine Leptospira surveillance,preferably using PCR methods,which are more sensitive than traditional culture-based methods.

关键词： Leptospirosis Prevalence China PCR Culture Reservoir

Manipulating submolecular-scale phototautomerization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Materials 2024年第6期67卷 2048-2050页

作者： Ping Zhou hongliang Chen Stoddart Institute of Molecular Science Department of ChemistryZhejiang UniversityHangzhou 310058China Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311215China

A recent study on the submolecular-scale control of phototautomerization methods and the underlying reaction mechanisms was reported in Nature Nanotechnology by Guillaume and co-workers[1],elucidating how the field confinement effect generated by the scanning tunneling microscope(STM)tip precisely triggers the phototautomerization of a free-base phthalocyanine at the submolecular level and demonstrating that the reaction process can be finely controlled by adjusting either the laser excitation wavelength or the position of the tip.

关键词： tunneling excitation phthalocyanine

High performance photodegradation resistant PVA@TiO_(2)/carboxyl-PES self-healing reactive ultrafiltration membrane

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第2期66卷 31-39页

作者： Yu Liang Yuanfang Fan Zhongmin Su Mingxin Huo Xia yang hongliang Huo Chi Wang Zhi Geng College of Environment Engineering Research Center of Low-Carbon Treatment and Green Development of Polluted Water in Northeast ChinaMinistry of EducationNortheast Normal UniversityChangchun 130117China School of Science Hainan UniversityHaikou 570225China

The occurrence of ultrafiltration(UF)membrane fouling frequently hampers the sustainable advancement of UF *** self-cleaning UF membranes can effectively alleviate the problem of membrane ***,the self-cleaning process may accelerate membrane *** these concerns,we present an innovative design concept for composite self-healing materials based on self-cleaning UF *** begin,TiO_(2)nanoparticles were incorporated into the polymer molecular structure via molecular design,resulting in the synthesis of TiO_(2)/carboxyl-polyether sulfone(PES)hybrid ***,the nonsolvent-induced phase inversion technique was employed to prepare a novel of UF ***,a polyvinyl alcohol(PVA)hydrogel coating was applied to the hybrid UF membrane surface to create PVA@TiO_(2)/carboxyl-PES self-healing reactive UF *** establishing a covalent bond,the TiO_(2)nanoparticles were effectively and uniformly dispersed within the UF membrane,leading to exceptional self-cleaning ***,the water-absorbing and swelling properties of PVA hydrogel,along with its capacity to form hydrogen bonds with water molecules,resulted in UF membranes with improved hydrophilicity and active self-healing *** results demonstrated that the water contact angle of PVA@5%TiO_(2)/carboxyl-PES UF membrane was 43.1°.Following a 1-h exposure to simulated solar exposure,the water flux recovery ratio increased from 48.16%to 81.03%.Moreover,even after undergoing five cycles of 12-h simulated sunlight exposure,the UF membranes exhibited a consistent retention rate of over 97%,thus fully demonstrating their exceptional self-cleaning,antifouling,and selfhealing *** anticipate that the self-healing reactive UF membrane system will serve as a pioneering and comprehensive solution for the self-cleaning antifouling challenges encountered in UF membranes while also effectively mitigating the aging effects of reactive

关键词： Ultrafiltration membrane Self-cleaning Self-healing Poly(aryl ether sulfone)

Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第2期35卷 118-130页

作者： Zihan Liu Han Liu Jialing Cheng hongliang Wang Yanfang yang Jun Ye Yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China

Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe *** are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse *** the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,reducing side effects,and improving patient *** this review,we summarize the pathophysiological characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating ***,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of *** but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field.

关键词： Ulcerative colitis Physiological characteristics Colon-specific drug delivery Mechanisms of action Targeted therapy of UC

An Energy Trading Method Based on Alliance Blockchain and Multi-Signature

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第2期78卷 1611-1629页

作者： hongliang Tian Jiaming Wang College of Electrical Engineering Northeast Electric Power UniversityJilin132012China

Blockchain,known for its secure encrypted ledger,has garnered attention in financial and data transfer realms,including the field of energy ***,the decentralized nature and identity anonymity of user nodes raise uncertainties in energy *** broadcast consensus authentication slows transaction speeds,and frequent single-point transactions in multi-node settings pose key exposure risks without protective measures during user *** address these,an alliance blockchain scheme is proposed,reducing the resource-intensive identity verification among *** integrates multi-signature functionality to fortify user resources and transac-tion security.A novel multi-signature process within this framework involves neutral nodes established through central *** neutral nodes participate in multi-signature’s signing and verification,ensuring user identity and transaction content *** interactions among user nodes enhances transaction efficiency by minimizing communication overhead during verification and consensus *** assessments on reliability and operational speed highlight superior security performance,resilient against conventional attack *** shows that compared to traditional solutions,this scheme has advantages in terms of running *** conclusion,the alliance blockchain framework introduces a novel approach to tackle blockchain’s limitations in energy *** integrated multi-signature process,involving neutral nodes,significantly enhances security and *** scheme’s efficiency,validated through analytical assessments and simulations,indicates robustness against security threats and improved transactional *** research underscores the potential for improved security and efficiency in blockchain-enabled energy trading systems.

关键词： Alliance blockchain multi-signature energy trading security performance transaction efficiency

A Blockchain-Based Access Control Scheme for Reputation Value Attributes of the Internet of Things

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第1期78卷 1297-1310页

作者： hongliang Tian Junyuan Tian College of Electrical Engineering Northeast Electric Power UniversityJilin132012China

The Internet of Things(IoT)access controlmechanism may encounter security issues such as single point of failure and data *** address these issues,a blockchain-based IoT reputation value attribute access control scheme is ***,writing the reputation value as an attribute into the access control policy,and then deploying the access control policy in the smart contract of the blockchain system can enable the system to provide more fine-grained access control;Secondly,storing a large amount of resources fromthe Internet of Things in Inter Planetary File System(IPFS)to improve system throughput;Finally,map resource access operations to qualification tokens to improve the performance of the access control *** simulation experiments based on the Hyperledger Fabric *** simulation experimental results,it can be seen that the access control system can achieve more fine-grained and dynamic access control while maintaining high throughput and low time delay,providing sufficient reliability and security for access control of IoT devices.

关键词： Blockchain IoT access control Hyperledger Fabric

基于有限差分法的高地应力隧道平导支护失效对正洞影响分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

兰州工业学院学报 2024年第3期31卷 37-43页

作者：雷飞田浩晟王雪冰刘大伟杨宏亮罗卫东伍正锟中国铁路昆明局集团有限公司滇西铁路建设指挥部云南昆明650200 西南交通大学交通隧道工程教育部重点实验室四川成都610031 中铁隧道局集团建设有限公司广东佛山528299 中铁二院昆明勘查设计研究院有限公司云南昆明650200

为探究高地应力下隧道平导支护结构破坏后的影响范围及对正洞影响程度,以丽香铁路在建玉龙雪山特长隧道为依托工程,采用数值模拟的方法,分析平导正洞不同净距及不同失效程度下,正洞围岩变形及支护结构受力变化规律,探明了正洞对不同情... 详细信息

为探究高地应力下隧道平导支护结构破坏后的影响范围及对正洞影响程度,以丽香铁路在建玉龙雪山特长隧道为依托工程,采用数值模拟的方法,分析平导正洞不同净距及不同失效程度下,正洞围岩变形及支护结构受力变化规律,探明了正洞对不同情况下平导支护失效的敏感程度。结果表明:平导支护体系完全失效所导致的正洞支护结构受力变化随净距减小呈先增大后减小的趋势,净距为1.5倍平导跨度时对正洞变形影响程度最大;正洞结构受力变化对平导径向锚杆失效最为敏感。高地应力隧道下平导支护结构失效对正洞影响较大,应对平导进行回填土或加强支护等措施,研究成果可为类似工程施工优化提供参考。

关键词：铁路隧道支护失效数值模拟平行导洞现场监测

Biomimetic leaf structures for ultra-thin electromagnetic wave absorption

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第5期17卷 4507-4516页

作者： Shikun Hou Ying Wang Feng Gao Fei Jin Benfeng Zhu Qiong Wu hongliang Ge Zhihai Cao Hua yang Magnetism Key Laboratory of Zhejiang Province&College of Optical and Electronic Technology China Jiliang UniversityHangzhou 310018China Department of Materials Science and Engineering Guangdong Technion-Israel Institute of TechnologyShantou 515063China Key Laboratory of Advanced Textile Materials and Manufacturing Technology and Engineering Research Center for Eco-Dyeing&Finishing of Textiles Ministry of EducationZhejiang Sci-Tech UniversityHangzhou 310018China

Ultra-thin electromagnetic wave(EMW)absorbers present challenging demands on EMW absorption *** inspiration from heather leaf structures,this study introduces an innovative design strategy for EMW absorbing material,proposing biomimetic leaf SnO_(2) structures(bio-SnO_(2))on carbon fabric(CF).By employing leaf-shaped SnS2 as precursors,biomimetic leaf SnO_(2) nanostructures are constructed on CF surface after a simple thermal treatment,resulting in bio-SnO_(2)@CF *** results indicate that bio-SnO_(2)@CF exhibits an exceptional minimum reflection loss of-54.8 dB at an incredibly thin thickness of 1.2 *** cross section(RCS)simulations further validate the outstanding EMW attenuation ability of bio-SnO_(2)@CF,attaining a maximum RCS reduction value of 16.9 dBm^(2) at an incident wave angle ofθ=0°.This novel research showcases the biomimetic structural design strategy and its remarkable function in enhancing the EMW absorbing performance at ultra-thin absorber thickness.

关键词： biomimetic leaf structures electromagnetic wave absorption ultra-thin thickness

Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第2期14卷 602-622页

作者： Han Liu Zhiyang Wen Zihan Liu Yanfang yang hongliang Wang Xuejun Xia Jun Ye Yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China

Calcium-based biomaterials have been intensively studied in the field of drug delivery owing to their excellent biocompatibility and ***-based materials can also deliver contrast agents,which can enhance real-time imaging and exert a Ca^(2+)-interfering therapeutic *** on these characteristics,amorphous calcium carbonate(ACC),as a brunch of calcium-based biomaterials,has the potential to become a widely used *** functional ACC can be either discovered in natural organisms or obtained by chemical synthesis However,the standalone presence of ACC is unstable in *** are required to be used as stabilizers or core-shell structures formed by permeable layers or lipids with modified molecules constructed to maintain the stability of ACC until the ACC carrier reaches its *** has high chemical instability and can produce biocompatible products when exposed to an acidic condition in vivo,such as Ca^(2+) with an immune-regulating ability and CO_(2) with an imaging-enhancing *** to these characteristics,ACC has been studied for selfsacrificing templates of carrier construction,targeted delivery of oncology drugs,immunomodulation,tumor imaging,tissue engineering,and calcium *** in this paper has been placed on the origin,structural features,and multiple applications of ***,ACC faces many challenges in clinical translation,and long-term basic research is required to overcome these *** hope that this study will contribute to future innovative research on ACC.

关键词： Amorphous calcium carbonate Drugdelivery system Nanoparticle Acid sensitivity Water instability,Tumortherapy Tissue engineering Calcium supplement