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囊壁切除膝关节镜下后内双通道技术治疗腘窝囊肿的效果

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中外医学研究 2024年第15期22卷 48-52页

作者：刘晟罗浩门宏亮李杰赵绍宏金希张利恒长春中医药大学吉林长春130117 吉林省人民医院

目的:探讨囊壁切除膝关节镜下后内双通道技术治疗腘窝囊肿的效果。方法:选取2019年9月—2022年9月吉林省人民医院收治的218例腘窝囊肿患者,根据随机数表法将其分为对照组(n=109)和观察组(n=109)。对照组给予保留囊壁膝关节镜下内引流技... 详细信息

目的:探讨囊壁切除膝关节镜下后内双通道技术治疗腘窝囊肿的效果。方法:选取2019年9月—2022年9月吉林省人民医院收治的218例腘窝囊肿患者,根据随机数表法将其分为对照组(n=109)和观察组(n=109)。对照组给予保留囊壁膝关节镜下内引流技术,观察组给予囊壁切除膝关节镜下后内双通道技术。比较两组围手术期指标,术前及术后6个月膝关节功能、疼痛程度及腘窝囊肿程度,并发症及复发。结果:观察组术后首次下地行走时间早于对照组,总住院时间短于对照组,差异有统计学意义(P0.05)。观察组复发率低于对照组,差异有统计学意义(χ^(2)=4.317,P<0.05)。结论:囊壁切除膝关节镜下后内双通道技术可更为有效地缓解腘窝囊肿患者的囊肿程度及疼痛,优化膝关节功能,且治疗安全性有保障。

关键词：腘窝囊肿关节镜膝关节功能并发症

维普期刊数据库博看期刊

Double-layered osmotic pump controlled release tablets of actarit: In vitro and in vivo evaluation

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Asian Journal of Pharmaceutical Sciences 2019年第3期14卷 340-348页

作者： Yuenan Li hao Pan hongliang Duan Jianting Chen Zhihong Zhu Jingxin Fan Pingfei Li Xinggang Yang Weisan Pan Shenyang Pharmaceutical University No.103Wenhua RoadShenyang CityLiaoning Province110016China Liao Ning University No.66Chongshan Middle RoadHuanggu DistrictShenyang CityLiaoning Province110036China

The aim of the study was to develop actarit double-layered osmotic pump tablets to overcome the weak points of actarit common tablets, such as short half-life and large plasma concentration fluctuations. Single factor experiment and orthogonal test were applied to optimize the formulation;the pharmacokinetic study was performed in beagle dogs adopting actarit common tablets as reference tablets. The optimal formulation was as follows: drug layer: 150 mg actarit, 240 mg PEO-N80, 50 mg NaCl;push layer: 140 mg PEO-WSR303, 20 mg NaCl;coating solution: 30 g cellulose acetate and 6 g PEG 4000 in 1000 ml 94% acetone solution, 60 mg coating weight gain. The pharmacokinetic study showed that T max was prolonged by the contrast of commercial common tablets with constant drug release rate, but the bioavailability was equivalent. And a good in vivo –in vitro correlation of the actarit osmotic pump tablets was also established. The designed actarit osmotic pump tablets can be applied for rheumatoid arthritis, proposing a promising replacement for the marked common products.

关键词： Actarit Double-layered Osmotic pump tablet Pharmacokinetics In vivo –in vitro correlation

Hard carbons derived from pine nut shells as anode materials for Na-ion batteries

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Chinese Physics B 2019年第6期28卷 32-37页

作者： hao Guo Kai Sun Yaxiang Lu hongliang Wang Xiaobai Ma Zhengyao Li Yong-Sheng Hu Dongfeng Chen China Institute of Atomic Energy Beijing 102413China Key Laboratory for Renewable Energy Beijing Key Laboratory for New Energy Materials and DevicesBeijing National Laboratory for Condensed Matter PhysicsInstitute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China

Hard carbons as promising anode materials for Na-ion batteries(NIBs) have captured extensive attention because of their low operation voltage, easy synthesis process, and competitive specific capacity. However, there are still several disadvantages, such as high cost and low initial coulombic efficiency, which limit their large-scale commercial ***, pine nut shells(PNSs), a low-cost biomass waste, are used as precursors to prepare hard carbon materials. Via a series of washing and heat treatment procedures, a pine nut shell hard carbon(PNSHC)-1400 sample has been obtained and delivers a reversible capacity of around 300 mAh/g, a high initial coulombic efficiency of 84%, and good cycling performance. These excellent Na storage properties indicate that PNSHC is one of the most promising candidates of hard carbon anodes for NIBs.

关键词： Na-ion battery anode hard carbon pine nut shells

Field-tuned magnetic structure and phase diagram of the honeycomb magnet YbCl_(3)

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Science China(Physics,Mechanics & Astronomy) 2021年第3期64卷 84-89页

作者： YiQing hao hongliang Wo YiMeng Gu XiaoWen Zhang YiQing Gu ShiYi Zheng Yang Zhao GuangYong Xu Jeffrey WLynn Kenji Nakajima Naoki Murai WenBin Wang Jun Zhao State Key Laboratory of Surface Physics and Department of Physics Fudan UniversityShanghai 200433China NIST Center for Neutron Research National Institute of Standards and TechnologyGaithersburg 20899USA Department of Materials Science and Engineering University of MarylandCollege Park 20742USA J-PARC Center Japan Atomic Energy Agency(JAEA)Ibaraki 319-1195Japan Institute of Nanoelectronic Devices and Quantum Computing Fudan UniversityShanghai 200433China Collaborative Innovation Center of Advanced Microstructures Nanjing 210093China

We report thermodynamic and neutron diffraction measurements on the magnetic ordering properties of the honeycomb lattice magnet YbCl_(3). We find YbCl_(3) exhibits a Ne′el type long-range magnetic order at the wavevector(0, 0, 0) below TN= 600 *** magnetic order is associated with a small sharp peak in heat capacity and most magnetic entropy release occurs above the magnetic ordering temperature. The magnetic moment lies in-plane, parallel to the monoclinic a-axis, whose magnitude mYb= 0.86(3) μBis considerably smaller than the expected fully ordered moment of 2.24 μBfor the doublet crystal-field ground state. The magnetic ordering moment gradually increases with increasing magnetic field perpendicular to the ab-plane, reaching a maximum value of 1.6(2) μBat 4 T, before it is completely suppressed above ~ 9 T. These results indicate the presence of strong quantum fluctuations in YbCl_(3).

关键词： magnetic order neutron diffraction honeycomb lattice

免人工肾积水针状肾镜系统治疗儿童肾结石的疗效分析

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中华全科医学 2024年第5期22卷 817-819,877页

作者：扎西达杰平措桑布次旺于洪亮王建忠郝宗耀龚宾宾西藏山南市人民医院泌尿外科西藏山南856000 安徽医科大学第一附属医院泌尿外科安徽合肥230022

目的探讨免人工肾积水针状肾镜系统(Needle-perc)辅助经皮肾镜碎石(percutaneous nephrolithotripsy,PCNL)治疗儿童肾结石的安全性和有效性。方法收集2021年8月—2022年10月期间山南市人民医院收治的11儿童肾结石资料,其中男7例,女4例,... 详细信息

目的探讨免人工肾积水针状肾镜系统(Needle-perc)辅助经皮肾镜碎石(percutaneous nephrolithotripsy,PCNL)治疗儿童肾结石的安全性和有效性。方法收集2021年8月—2022年10月期间山南市人民医院收治的11儿童肾结石资料,其中男7例,女4例,年龄5~16岁,其中右侧4例,左侧7例,单发肾盂结石5例,多发结石6例,结石最大直径为(18.46±6.52)mm,结石的CT值为(835.04±135.74)HU。均在全麻下行免人工肾积水可视化针状肾镜系统穿刺辅助经皮肾镜钬激光碎石术,术中在超声引导下使用4.5Fr可视化穿刺针在直视下行目标肾盏穿刺,随后建立F16经皮肾通道,配合使用550μm钬激光完成碎石,术后留置F12造瘘管,其中完全可视化肾镜碎石则无管化处理。评估手术时间、手术并发症、术后住院时间及术后结石清除率情况。结果所有患儿均成功完成手术,其中行完全可视化肾镜下钬激光碎石3例,8例行可视化穿刺系统辅助下经皮肾镜激光碎石术,手术时间(79.55±10.76)min,术后血红蛋白下降(10.09±5.25)g/L,术后住院时间(5.54±1.07)d,术后4周复查结石清除率为100%。术中术后未出现通道丢失、感染发热、严重出血、肾脏及邻近器官损伤等严重并发症。结论免人工肾积水针状肾镜辅助经皮肾镜碎石治疗儿童肾结石安全、有效,且手术并发症发生率低,可以达到满意的结石清除率,适合儿童肾结石的个体化治疗,在高原儿童肾结石好发地区具有一定的临床推广应用价值。

关键词：儿童肾结石经皮肾镜碎石术针状肾镜临床疗效

Generating a sub-nanometer-confined optical field in a nanoslit waveguiding mode

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Advanced Photonics 2023年第4期5卷 33-41页

作者： Liu Yang Zhanke Zhou hao Wu hongliang Dang Yuxin Yang Jiaxin Gao Xin Guo Pan Wang Limin Tong Zhejiang University College of Optical Science and EngineeringNew Cornerstone Science LaboratoryInterdisciplinary Center for Quantum InformationHangzhouChina Jiaxing Institute of Zhejiang University Intelligent Optics and Photonics Research CenterJiaxingChina Shanxi University Collaborative Innovation Center of Extreme OpticsTaiyuanChina

We propose to generate a sub-nanometer-confined optical field in a nanoslit waveguiding mode in a coupled nanowire pair(CNP).We show that,when a conventional waveguide mode with a proper polarization is evanescently coupled into a properly designed CNP with a central nanoslit,it can be efficiently channeled into a high-purity nanoslit mode within a waveguiding length<10μ*** CNP can be either freestanding or on-chip by using a tapered fiber or planar waveguide for input-coupling,with a coupling efficiency up to 95%.Within the slit region,the output diffraction-limited nanoslit mode offers an extremely confined optical field(∼0.3 nm×3.3 nm)with a peak-to-background ratio higher than 25 dB and can be operated within a 200-nm *** group velocity dispersion of the nanoslit mode for ultrafast pulsed operation is also briefly *** with the previous lasing configuration,the waveguiding scheme demonstrated here is not only simple and straightforward in structural design but is also much flexible and versatile in ***,the waveguiding scheme we show here may offer an efficient and flexible platform for exploring light–matter interactions beyond the nanometer scale,and developing optical technologies ranging from superresolution nanoscopy and atom/molecule manipulation to ultra-sensitivity detection.

关键词： sub-nm confined optical field nanoslit evanescent coupling waveguide mode

Epitaxial fabrication of two-dimensional TiTe_2 monolayer onAu(111) substrate with Te as buffer layer

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Chinese Physics B 2019年第5期28卷 16-19页

作者： Zhipeng Song Bao Lei Yun Cao Jing Qi hao Peng Qin Wang Li Huang hongliang Lu Xiao Lin Ye-Liang Wang Shixuan Du Hong-Jun Gao Institute of Physics and University of Chinese Academy of Sciences Chinese Academy of Sciences CAS Center for Excellence in Topological Quantum Computation School of Information and Electronics Beijing Institute of Technology

Two-dimensional(2 D) materials provide a platform to exploit the novel physical properties of functional ***, we report on the formation of a new 2 D layered material, a well-ordered monolayer TiTe_2, on a Au(111) surface by molecular beam epitaxy(MBE). Low-energy electron diffraction(LEED) measurements of the samples indicate that the TiTe_2 film forms(√3 ×√7) superlattice with respect to the Au(111) substrate, which has three different orientations. Scanning tunneling microscopy(STM) measurements clearly show three ordered domains consistent with the LEED *** functional theory(DFT) calculations further confirm the formation of 2 H-TiTe_2 monolayer on the Au(111) surface with Te as buffer layer. The fabrication of this 2 D layered heterostructure expands 2 D material database, which may bring new physical properties for future applications.

关键词： TiTe2 epitaxial fabrication superlattice scanning tunneling microscopy (STM) low-energy electron diffraction (LEED)

Frustrated Magnetic Interactions and Quenched Spin Fluctuations in CrAs

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Chinese Physics Letters 2022年第12期39卷 89-93页

作者： Yayuan Qin Yao Shen Yiqing hao hongliang Wo Shoudong Shen Russell A.Ewings Yang Zhao Leland W.Harriger Jeffrey W.Lynn Jun Zhao State Key Laboratory of Surface Physics and Department of Physics Fudan UniversityShanghai 200433China Shanghai Qizhi Institute Shanghai 200232China ISIS Pulsed Neutron and Muon Source STFC Rutherford Appleton LaboratoryHarwell CampusDidcotOxonOX110QXUnited Kingdom NIST Center for Neutron Research National Institute of Standards and TechnologyGaithersburgMD 20899USA Department of Materials Science and Engineering University of MarylandCollege ParkMD 20742USA Institute of Nanoelectronics and Quantum Computing Fudan UniversityShanghai 200433China Shanghai Research Center for Quantum Sciences Shanghai 201315China

The discovery of pressure-induced superconductivity in helimagnets(CrAs,MnP)has attracted considerable interest in understanding the relationship between complex magnetism and unconventional ***,the nature of the magnetism and magnetic interactions that drive the unusual double-helical magnetic order in these materials remains ***,we report neutron scattering measurements of magnetic excitations in CrAs single crystals at ambient *** experiments reveal well defined spin wave excitations up to about 150 meV with a pseudogap below 7 meV,which can be effectively described by the Heisenberg model with nearest neighbor exchange *** surprisingly,the spin excitations are largely quenched above the Néel temperature,in contrast to cuprates and iron pnictides where the spectral weight is mostly preserved in the paramagnetic *** results suggest that the helimagnetic order is driven by strongly frustrated exchange interactions,and that CrAs is at the verge of itinerant and correlation-induced localized states,which is therefore highly pressure-tunable and favorable for superconductivity.

关键词： excitation exchange pressure

Cardiac autonomic nerve fiber regeneration in chronic heart failure Do Akt gene-transduced mesenchymal stem cells promote repair?

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Neural Regeneration Research 2010年第1期5卷 28-34页

作者： hongliang Kong Zhanquan Li Shumei Zhao Li Zhu Yingjun Zhao Weiwei Zhang GuipingXu Wenjun hao Huijun Li Guoxian Qi Department of Cardiology the First Affiliated Hospital of China Medical University Shenyang 110001 Liaoning Province China Department of Cardiology the People's Hospital of Liaoning Province Shenyang 110016 Liaoning Province China Shenyang Normal University Shenyang 110034 Liaoning Province China

BACKGROUND： Transplantation of Akt-over-expressing mesenchymal stem ceils （Akt-MSCs） has been shown to repair infarcted myocardium and improve cardiac function. However, little is known about the therapeutic effects of Akt-MSCs on cardiac autonomic neuropathy in chronic heart failure （CHF）. OBJECTIVE： The present study used adriamycin-induced CHF rat models to observe the effect of Akt-MSCs on cardiac autonomic nervous regeneration and the factors mediating this effect. DESIGN, TIME AND SETTING： A randomized, controlled animal experiment was performed at the Central Laboratory of Basic Medical College, China Medical University, between September 2008 and April 2009. MATERIALS： Rabbit anti-choline acetyltransferase （CHAT）, growth associated protein-43 （GAP-43） synaptophysin （SYN） polyclonal antibodies and the secondary antibody （goat anti-rabbit IgG） were purchased from Boster, China. Cat-A-Kit assay system was provided by Amersham, USA. METHODS：（1） Adult rat MSCs were isolated and cultured for the preparation of Akt-MSCs. （2） Forty male Wistar rats were intramyocardially administered adriamycin at 2 mg/kg over 3 days for a total of five times and once a week for additional five times thereafter to establish CHF models. At 2 weeks after final adriamycin treatment, 34 successful CHF rat models were randomized to three groups： Akt-MSCs （n = 11）, simple MSCs （s-MSCs, n =11）, and control （n = 12）. Each group was intravenously administered Akt-MSCs （2x106 cells in 100 IJL PBS）, s-MSCs （2×10^6 cells in 100 μL PBS） or equal volume of phosphate buffered saline, once a day for a total of three times. MAIN OUTCOME MEASURES： At 4 weeks after final adriamycin treatment, myocardial norepinephrine （NE） content was detected using a Cat-A-Kit assay system. Myocardial CHAT, SYN and GAP-43 were performed by immunohistochemistry and Western blot analysis. Prior to, 2 and 4 weeks after adriamycin treatment, echocardiographic examination was performed and left ventricular ejection fract

关键词： mesenchymal stem cells Akt gene transfection chronic heart failure neural regeneration autonomic nerve system