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Efficacy and safety of transvaginal mesh repair in a cohort with a minimum of 10-year follow-up

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Sc.ence china(Life Sc.ences) 2024年第5期67卷 1061-1068页

作者： Zhibo Zhang Jianbin Guo Weijie Tian Ye Zhang Yuelun Zhang Tianshu Sun Jiali Duan Xinmiao Bao Yuan Wang Yang Ye Qianqian Gao honghui Shi Abraham Nick Morse Juan c.en Lan Zhu Departmentof Obstetrics and Gynecology Peking Union MedicalCollege HospitalChinese Academyof Medical Sciences&Peking Union MedicalCollegeNational Clinical Research Center for Obstetricand Gynecologic DiseasesBeijing 100730China Department of Gynecology Guizhou Provincial People’s HospitalMedical College of Guizhou UniversityGuiyang 550002China Department of Obstetrics and Gynecology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China Medical Research center Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Medical Doctor Program Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Pathology Peking Union Medical College HospitalBeijing 100730China Tufts University School of Medicine Boston MA 02111USA

Although transvaginal mesh(TVM)repair is no longer used in some countries,long-term outcomes after TVM surgery are of great importance ***,reports with follow-up>10 years are ***,this study aimed to report outcomes in a prospective cohort with at least 10 years of *** with stageⅢ–Ⅳsymptomatic prolapse were approached consecutively from 2008 to 2013 at one tertiary *** main outcome measure was symptomatic *** outcomes included anatomic failure,recurrence,patient satisfaction,complications,and *** Kaplan-Meier curve was used to estimate the cumulative failure *** the 121 patients enrolled in the study,103(85.1%)completed a median follow-up of 11 *** estimated probability rates of symptomatic and anatomic failure were 17.6%and 8.8%in 11 years,*** estimated incidence of symptomatic failure increased by 8.2%between 5 and 11 years;however,the corresponding rate for anatomic failure was 3.7%.The most common complication was vaginal mesh exposure,and its estimated probability increased from 19.3%to 28.4%from 5 to 11 years,*** trimming resolved 80.0%of vaginal *** patients did not report decreased overall *** with vaginal mesh exposure requiring>3 office procedures or mesh removal in the operating room(5.8%by 11 years)had lower satisfaction rates(Pent Global Impression of Improvement≥2 were 2.5%,3.3%,and 94.2%,*** results of this study implied that TVM treatment gradually increased the symptomatic failure rate but provided durable anatomical support of the vaginal *** mesh exposure was common in women who were largely not sexually active;however,80%of the cases could be managed in the outpatient clinic,which did not affect patient satisfaction.

关键词： complication efficacy long-term follow-up pelvic organ prolapse safety transvaginal mesh

氮添加对内蒙古草原植物地上和地下碳氮磷化学计量学特征的影响

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Journal of Plant Ecology 2024年第1期17卷 57-67页

作者： Ziqi Wang Jie Wang honghui Wu Tian Yang Yixin An Yunlong Zhang Jianlin Bian Ying Li Haiyan Ren Ariuntsetseg Lkhagva Xu Wang Qiang Yu School of Grassland Sc.ence Beijing Forestry UniversityBeijing 100083China National Hulunber Grassland Ecosystem Observation and Research Station Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Ministry of Agriculture Key Laboratory of crop Nutrition and Fertilization Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081China Department of Biology University of Western OntarioLondonONCanada college of Grassland Sc.ence and Technology China Agricultural UniversityBeijing 100083China college of Resource environment and Tourism Capital Normal UniversityBeijing 100048China college of Agro-grassland Sc.ence Nanjing Agricultural UniversityNanjing 210095China Department of Biology School of Arts and SciencesNational University of MongoliaUlaanbaatar 14200Mongolia

氮沉降对生态系统功能和过程具有显著影响。已有研究表明氮添加会影响植物叶片c:N:P化学计量特征。然而,氮添加对植物根系c:N:P化学计量特征影响的研究罕有报道。本论文的主要目的是对比氮添加对草原植物群落地上和地下c:N:P化学计量特... 详细信息

氮沉降对生态系统功能和过程具有显著影响。已有研究表明氮添加会影响植物叶片c:N:P化学计量特征。然而,氮添加对植物根系c:N:P化学计量特征影响的研究罕有报道。本论文的主要目的是对比氮添加对草原植物群落地上和地下c:N:P化学计量特征的影响。我们在内蒙古锡林郭勒草原开展了一个7年的氮添加实验,该实验包括6个处理,分别是对照:control;N1:0.4 mol·m-2 N;N2:0.8 mol·m^(-2) N;N3:1.6 mol·m^(-2) N;N4:2.8 mol·m^(-2) N;N5:4 mol·m^(-2) N,每个处理6次重复。我们测量并分析了植物地上、地下生物量和c:N:P化学计量特征。研究结果表明,氮添加会导致植物群落地上部分碳浓度降低,氮浓度和磷浓度升高,c:N和c:P比值降低,N:P升高,而且地上碳、氮、磷库均因施氮而增加。然而,氮添加对0-10,10-30,30-50和50-100 cm 4个土层的地下部分碳、氮、磷浓度、比例、库和化学计量特征没有显著影响。综上所述,氮添加会显著改变植物群落地上部分c:N:P化学计量特征,进而影响草地生态系统的功能和过程,但对地下c:N:P化学计量特征几乎没有影响。

关键词：氮沉降 c:N:P 化学计量草地生态系统群落地下

cell-free supernatants of Bacillus inhibit the biofilms of Pseudomonas lundensis cultured with and without Acinetobacter johnsonii

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微生物学报 2024年第10期64卷 3886-3900页

作者： WU Shiyuan LU Zhong SHI honghui ZHANG Jun LU Haixia ZHU Junli School of Food Sc.ence and Biotechnology Zhejiang Gongshang UniversityHangzhou 310018ZhejiangChina

[Objective] Pseudomonas as one of the dominant spoilage bacteria highly form biofilms in chilled meat products and processing environment when contaminating single or mixed with other *** study aims to investigate the antibiofilm properties of the cell-free supernatants(cFSs) of three Bacillus species isolated from fermented food and rice seeds on Pseudomonas lundensis(PL) or and Acinetobacter johnsonii(AJ) as mono-or dual-species.[Methods] Biofilm biomass,extracellular polymeric substances(EPSs),and biofilm structure were measured by crystal violet staining,spectrophotometry,confocal laser scanning microscopy(cLSM),respectively,as well as transcription of biofilm-related genes determined by qPcR.[Results] The cFSs of Bacillus amyloliquefac.ens ZG08,*** B5,and *** YB11 inhibited the biofilm formation of PL and AJ without affecting their *** treatment with 50% cFSs of ZG08 and B5 decreased the cell viability of two biofilms by 12.73%–21.04%,which was higher than that of YB11(0.15%–4.38%).The inhibition rates of 50% cFSs of the three strains were 59.75%–79.59% against the PL biofilm and 63.62%–78.57% against the biofilm of PL+AJ,in which the cFS of YB11 had weaker *** content of exopolysaccharides and exoprotein in the two biofilms treated with these cFSs were reduced by 53.77%–73.30% and 54.84%–62.38%,*** treatment with the three cFSs also reduced the adhesive cells,loosened biofilm structures,and thinned their thickness by 57.63%–74.49% and 60.43%–64.64%,***,the cFSs of ZG08 and B5 effectively eradicated by 41.77%–69.79% against the mature biofilms of PL and PL+AJ,compared to weak activity of *** addition,the antibiofilm activities of the three cFSs were stable under four enzyme digestion and heating *** with the control,the cFSs of ZG08 and B5 significantly down-regulated the expression of six biofilm-related genes,lapA,alg44,pelG,luxR,wspR,and rpoS.[conclusion] The cFSs of

关键词： Bacillus spp. cell-free supernatant antibiofilm Pseudomonas lundensis Acinetobacter johnsonii biofilm of mixed species

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声门下支气管源性囊肿1例

中华耳鼻咽喉头颈外科杂志 2024年第2期59卷 177-179页

作者：宋柳杨慧景星涛张宏慧四川大学华西医院耳鼻咽喉-头颈外科成都610041

患者女,36岁,因“咽部异物感1个月余,呼吸困难15 d”就诊。门诊电子纤维喉镜提示,声门下一半球形肿物隆起,突入并堵塞气道90%,遂紧急行气管切开术。术前颈部增强cT见c6平面喉咽右侧壁软组织结节影凸向气管腔,边缘见低密度影。急诊在全... 详细信息

患者女,36岁,因“咽部异物感1个月余,呼吸困难15 d”就诊。门诊电子纤维喉镜提示,声门下一半球形肿物隆起,突入并堵塞气道90%,遂紧急行气管切开术。术前颈部增强cT见c6平面喉咽右侧壁软组织结节影凸向气管腔,边缘见低密度影。急诊在全身麻醉下行经口支撑喉镜下cO 2激光声门下肿物切除术。病理标本大体检查示,肿瘤大小2.0 cm×1.0 cm,剖开内为黏稠胶冻样组织,囊壁厚0.2 cm,术后病理诊断为支气管源性囊肿。患者于术后第2天堵管,术后3 d出院,出院1年复查未见肿物复发,预后良好。

关键词：咽部异物感支气管源性囊肿肿物切除术病理标本声门下预后良好结节影低密度影

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兵团企业在科技创新中的主体地位提升研究

兵团党校学报 2024年第1期206卷 155-160,F0003页

作者：魏吟雪祝宏辉石河子大学新疆石河子832000

优化兵团科技结构,强化企业在兵团科技创新体系中的主体地位,对建设以企业为主体、市场为导向、产学研相结合的科技创新体系具有重要意义。通过对2017—2022年兵团龙头企业、高校和科研机构科技创新人员与经费投入、专利与创新项目产出... 详细信息

优化兵团科技结构,强化企业在兵团科技创新体系中的主体地位,对建设以企业为主体、市场为导向、产学研相结合的科技创新体系具有重要意义。通过对2017—2022年兵团龙头企业、高校和科研机构科技创新人员与经费投入、专利与创新项目产出的梳理与整理,发现兵团企业科技创新主体地位逐步强化,但仍存在创新意识薄弱、创新能力不足、创新企业梯队建设不完善等问题。通过加快构建以企业为主体的兵团“政产学研用”协同创新体系,加速培育兵团科技创新型企业梯队、支持大型国有企业开展基础创新研究等措施,能有效提升兵团企业科技创新能力和地位。

关键词：企业科技创新主体地位

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Adaptive optimization of agile organization of command and control resource

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Journal of Systems engineering and Electronics 2009年第3期20卷 558-564页

作者： Yang chunhui Liu Junxian c.en honghui Luo Xueshan Dept. of Management Naval Univ. of Engineering Wuhan 430033 P. R. China Key Lab. of c^4ISR National Univ. of Defense Technology Changsha 410073 P. R. China

Adaptive optimization is one of the means that agile organization of command and control resource （AOc2R） adapts for the dynamic battlefield environment. A math model of the adaptive optimization of AOc2R is put forward by analyzing the interrelating concept and research. The model takes the adaptive process as a multi-stage decision making problem. The 2-phases method is presented to calculate the model, which obtains the related parameters by running the colored Petri net （cPN） model of AOc2R and then searches for the result by ant colony optimization （AcO） algorithm integrated with genetic optimization techniques. The simulation results demonstrate that the proposed algorithm greatly improves the performance of AOc2R.

关键词： command and control organization adaptive optimization of organization dynamic-window-search ant colony optimization 3-phase organizational design.

GDM孕妇产后糖代谢转归失败危险因素分析及预测价值

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中国计划生育学杂志 2024年第3期32卷 680-684页

作者：陈红惠陆卫南通大学附属妇幼保健院 226000

目的:分析妊娠期糖尿病(GDM)孕妇产后糖代谢转归失败危险因素及其预测价值。方法:选取2021年3月-2023年5月在本院产科就诊的GDM患者214例临床资料,依据产后6~12周糖代谢转归情况分为转归失败组、转归正常组。收集患者孕前、孕期、新生... 详细信息

目的:分析妊娠期糖尿病(GDM)孕妇产后糖代谢转归失败危险因素及其预测价值。方法:选取2021年3月-2023年5月在本院产科就诊的GDM患者214例临床资料,依据产后6~12周糖代谢转归情况分为转归失败组、转归正常组。收集患者孕前、孕期、新生儿资料,通过多因素logistic回归分析确定患者产后糖代谢转归失败的独立危险因素,受试者工作特征(ROc)曲线观察独立危险因素预测产后糖代谢转归失败价值。结果:年龄、孕前BMI、糖尿病家族史、FPG、HbA1c及孕期使用胰岛素均为产后糖代谢转归失败的独立危险因素(Pc曲线显示,年龄≥35岁、孕前体质指数≥24 kg/m^(2)、糖尿病家族史、空腹血糖、糖化血红蛋白及孕期使用胰岛素均对GDM孕妇产后糖代谢转归失败有一定预测效能,曲线下面积(AUc)分别为0.582、0.590、0.638、0.858、0.651、0.609(均P<0.05)。结论:GDM孕妇产后糖代谢转归失败与年龄大、孕前BMI高、糖尿病家族史、血糖指标高、孕期使用胰岛素有关,且上述因素均对转归失败有一定预测价值。

关键词：妊娠期糖尿病产后糖代谢转归危险因素预测

二阶随机扰动下HBV流行病模型全局正解的存在唯一性与平稳分布

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青岛理工大学学报 2024年第3期45卷 151-161页

作者：周俊桦卢春刘洪辉青岛理工大学理学院青岛266525

提出一个二阶随机扰动下的乙型肝炎病毒(HBV)感染模型,并在垂直传播比例μωνc不被认为是新感染的条件下研究了该模型的动力学行为。首先,证明了该随机模型全局正解的存在唯一性。其次,通过构造合适的Lyapunov函数,证明了在Ros>1的情况... 详细信息

提出一个二阶随机扰动下的乙型肝炎病毒(HBV)感染模型,并在垂直传播比例μωνc不被认为是新感染的条件下研究了该模型的动力学行为。首先,证明了该随机模型全局正解的存在唯一性。其次,通过构造合适的Lyapunov函数,证明了在Ros>1的情况下,该随机模型平稳分布的存在唯一性和遍历性,并且得到了一个当噪声等于0时与基本再生数R0相等的随机临界值Ros。

关键词：乙型肝炎病毒模型随机干扰平稳分布

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浮筏式牡蛎养殖对大型底栖动物群落功能结构的影响——以大鹏澳为例

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热带海洋学报 2024年第5期43卷 69-83页

作者：饶义勇赵美榕旷泽行黄洪辉谭萼辉中国水产科学研究院南海水产研究所广东广州510300 广东省渔业生态环境重点实验室广东广州510300 海南大学南海海洋资源利用国家重点实验室海南海口570228

牡蛎养殖的环境生态效应存在争议,其对大型底栖动物的影响机理缺乏清晰认识。本研究于2020年11月(秋季)和2021年1月(冬季)在大鹏澳浮筏式牡蛎养殖区及邻近海域进行了2个航次大型底栖动物和相关环境因子的调查监测。2个航次共获得大型底... 详细信息

牡蛎养殖的环境生态效应存在争议,其对大型底栖动物的影响机理缺乏清晰认识。本研究于2020年11月(秋季)和2021年1月(冬季)在大鹏澳浮筏式牡蛎养殖区及邻近海域进行了2个航次大型底栖动物和相关环境因子的调查监测。2个航次共获得大型底栖动物103种,种类组成以多毛类、双壳类和甲壳类物种占优势。大型底栖动物群落的物种组成在季节间(秋季和冬季)和区域间(养殖区和对照区)具有显著差异。冬季大型底栖动物的种类数、栖息密度和生物量等群落参数高于秋季,对照区高于养殖区。生物性状分析(biological traits analysis,BTA)结果显示,大型底栖动物群落的性状组成仅在季节间具有显著差异。牡蛎养殖区和对照区大型底栖动物群落的性状组成差异不显著,但生物扰动方式、个体大小、摄食类型等性状在区域间仍有一定的差别。牡蛎养殖区大型底栖动物群落的功能丰富度(functional richness,Fric)低于对照区,但功能均匀度(functional evenness,Feve)和功能分散度(functional divergence,Fdiv)在区域之间的差异不大。表层水体的叶绿素a、悬浮物、营养盐以及沉积物的有机碳、硫化物和中值粒径是影响大型底栖动物物种组成和性状组成的重要环境因子。摄食类型、栖息方式以及幼体发育方式等性状与环境因子的关系比较密切,物种丰富度(d)和功能丰富度指数具有较高的环境指示意义。

关键词：大型底栖动物牡蛎养殖物种多样性功能多样性生物性状分析