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Devonian integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1036-1070页

作者： Wenkun QIE Kun LIANG Wen GUO Biao GAO Junjun SONG Bo chen Pu HUANG Li QIAO honghe XU Jitao chen Yucong SUN Yichun ZHANG State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Nanjing 211135China

The Devonian System in the Qinghai-Tibetan Plateau and its surrounding areas is widely distributed,diverse in lithotypes and rich in fossils.It records the crucial processes of continuous subduction and reduction of the Paleo-Asian Ocean in the northern hemisphere and the transformation of the Proto-Tethys Ocean into the Paleo-Tethys Ocean in the southern hemisphere.Thus,it is of great significance for explaining the global paleogeographic evolution,tectonic activities and biodiversity changes during this critical period.The blocks on both sides of the southern Tienshan suture zone and the Longmu Co-ShuanghuChangning-Menglian suture zone belong to different sedimentary systems and paleobiogeographic realms and regions,showing important tectonic paleogeographic partitioning significance.The two suture zones represent the main branches of the PaleoAsian Ocean and the Paleo-Tethys Ocean,respectively,and on this basis the Devonian System can be subdivided into three types:the Tienshan type,the Tethys type and the Gondwana type.Based on recent research progress on the Devonian stratigraphy and paleontology in combining provenance analysis and biotic characteristics in the Qinghai-Tibetan Plateau and surrounding areas,this paper aims to establish the latest integrative stratigraphic framework and conduct paleogeographic reconstruction,providing foundation for exploring the geological evolution and dynamic mechanisms of various terranes and blocks in the northern margin of Gondwana.The results indicate that the North Qiangtang,South Qiangtang,Simao,Baoshan and Tengchong terranes,as well as the Himalaya Tethys Zone and the South China Block have affinities with the Indian Block,while the Lhasa Terrane has affinities with the Australian Block,and may be located between the South China and Australian blocks.In the Emsian(Early Devonian),the South China Block separated from the northern margin of Gondwana,a process that was accompanied by the opening of the Jinshajiang-Ailaoshan Ocean.In the Middle Devonian,the mid-oceanic

关键词： Devonian Paleo-Tethys Ocean Integrative stratigraphy Biotas Provenance Analysis Paleogeography

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Different Responses of Two Highly Permissive Cell Lines Upon HCV Infection

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Virologica Sinica 2013年第4期28卷 202-208页

作者： honghe chen Rongjuan Pei Xinwen chen State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences University of Chinese Academy of Sciences

The construction of the first infectious clone JFH-1 speeds up the research on hepatitis C virus (HCV). However, Huh7 cell line was the only highly permissive cell line for HCV infection and only a few clones were fully permissive. In this study, two different fully permissive clones of Huh7 cells, Huh7.5.1 and Huh7-Lunet-CD81 (Lunet-CD81) cells were compared for their responses upon HCV infection. The virus replication level was found slightly higher in Huh7.5.1 cells than that in Lunet-CD81 cells. Viability of Huh7.5.1 cells but not of Lunet-CD81 cells was reduced significantly after HCV infection. Further analysis showed that the cell cycle of infected Huh7.5.1 cells was arrested at G1 phase. The G1/S transition was blocked by HCV infection in Huh7.5.1 cells as shown by the cell cycle synchronization analysis. Genes related to cell cycle regulation was modified by HCV infection and gene interaction analysis in GeneSpring GX in Direct Interactions mode highlighted 31 genes. In conclusion, the responses of those two cell lines were different upon HCV infection. HCV infection blocked G1/S transition and cell cycle progress, thus reduced the cell viability in Huh7.5.1 cells but not in Lunet-CD81 cells. Lunet-CD81 cells might be suitable for long term infection studies of HCV.

关键词：感染性克隆细胞株 HCV 反应丙型肝炎病毒细胞周期调控病毒感染相关基因

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The monkey microbial biobank brings previously uncultivated bioresources for nonhuman primate and human gut microbiomes

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mLife 2022年第2期1卷 210-217页

作者： Danhua Li Chang Liu Rexiding Abuduaini Mengxuan Du Yujing Wang Haizhen Zhu honghe chen Nan Zhou Yuhua Xin Linhuan Wu Juncai Ma Yuguang Zhou Yong Lu chengying Jiang Qiang Sun Shuang-Jiang Liu State Key Laboratory of Microbial Resources and Environmental Microbiology Research Center at Institute of Microbiology Chinese Academy of SciencesBeijingChina College of Life Science University of Chinese Academy of SciencesBeijingChina State Key Laboratory of Microbial Biotechnology Shandong UniversityQingdaoChina China General Microorganism Culture Collection Institute of MicrobiologyChinese Academy of SciencesBeijingChina Microbial Resources and Big Data Center Institute of MicrobiologyChinese Academy of SciencesBeijingChina State Key Laboratory of Neuroscience CAS Key Laboratory of Primate NeurobiologyCAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesInstitute of NeuroscienceShanghaiChina

Impact statement Nonhuman primates(NHPs)such as monkeys are the closest living relatives to humans and are the best available models for causative studies of human health and diseases.Gut microbiomes are intensively involved in host health.In this study,by large-scale cultivation of microbes from fecal samples of monkeys,we obtained previously uncultured bacterial species and constructed a Macaca fascicularis Gut Microbial Biobank(MfGMB).The MfGMB consisted of 250 strains that represent 97 species of 63 genera,25 families,and 4 phyla.The information of the 250 strains and the genomes of 97 cultured species are publicly accessible.The MfGMB represented nearly 50% of core gut microbial compositions at the genus level and covered over 80% of the KO-based known gut microbiome functions of M.fascicularis.Data mining showed that the bacterial species in the MfGMB were prevalent not only in NHPs gut microbiomes but also in human gut microbiomes.This study will help the understanding and future investigations on how gut microbiomes interact with their mammalian hosts.

关键词： statement monkey gut

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1944年延安卫生展览会中的宣传与动员

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中州大学学报 2024年第2期41卷 64-69,81页

作者：李洪河陈震华河南师范大学政治与公共管理学院河南新乡453007

抗日战争时期,延安的环境卫生和广大群众的不良生活习惯深深影响着民众的身体健康乃至革命事业的进程。为改变民众的愚昧迷信和不卫生习惯,推动延安卫生事业的发展,党和政府于1944年7月在延安杨家岭大礼堂筹办了以卫生防疫、妇婴卫生和... 详细信息

抗日战争时期,延安的环境卫生和广大群众的不良生活习惯深深影响着民众的身体健康乃至革命事业的进程。为改变民众的愚昧迷信和不卫生习惯,推动延安卫生事业的发展,党和政府于1944年7月在延安杨家岭大礼堂筹办了以卫生防疫、妇婴卫生和反对巫神迷信为主要内容的规模宏大的卫生展览会,并从会前筹备、氛围营造、会议过程设计和会后的模范评定多个方面进行了广泛的宣传和社会动员。此次卫生展览会以其丰富的展陈内容、多样的宣传形式使广大民众产生了强烈的思想共鸣,这对民众政治认同的提升、延安地区科学卫生观念的传播和中西医结合治疗方式的推动等都起到一定的积极作用。

关键词：延安卫生展览会社会动员社会影响

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水环境和水产品中β-N-甲氨基-L-丙氨酸(BMAA)检测方法和检出情况的研究进展

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环境化学 2024年第3期43卷 864-874页

作者：王琛刘桂华秦逍云刘红河姜杰杨胜园袁冠湘深圳市疾病预防控制中心深圳518055 南华大学公共卫生学院衡阳421001

本文对蓝藻毒素β-N-甲氨基-L-丙氨酸(β-N-methylamino-L-alanine,BMAA)的结构形态、检测方法、环境和食物中的检出情况等方面进行系统综述.研究结果表明,BMAA主要存在3种赋存形态(游离态、溶解结合态、沉淀结合态);环境和食物中的BMA... 详细信息

本文对蓝藻毒素β-N-甲氨基-L-丙氨酸(β-N-methylamino-L-alanine,BMAA)的结构形态、检测方法、环境和食物中的检出情况等方面进行系统综述.研究结果表明,BMAA主要存在3种赋存形态(游离态、溶解结合态、沉淀结合态);环境和食物中的BMAA类目前主要采用经过AQC衍生的LCMS/MS法检测,样品需经形态分离后、采用MCX固相萃取小柱处理.水环境、水产品和藻类保健品中BMAA类的污染已被大量报道.亚洲、北美洲、欧洲的相关环境和食物中均有一定的检出(检出浓度:水样<0.01—25.3μg·L^(-1);藻类<0.01—300μg·g^(-1);非鲨鱼水产品中0.08—115.3μg·g^(-1);藻类保健品中0.04—0.73μg·g^(-1)).BMAA存在生物积累和生物放大的现象,水产品中营养级别越高的生物检出浓度就越高,如鲨鱼类产品中检出浓度高达34—2011μg·g^(-1),需要引起重视.我国目前对BMAA的相关研究还很有限,未来应加强检测方法、现场调查、风险评估等相关方面的研究,以全面了解我国人群对BMAA类物质的暴露风险.

关键词： β-N-甲氨基-L-丙氨酸(BMAA) LC-MS/MS 水环境水产品藻类产品

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胆汁酸在畜禽及水产养殖中的应用

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中国饲料 2024年第13期 15-21页

作者：陈玉艳李静刘鸿鹤付师一谷旭刘璐马莹中国农业科学院饲料研究所北京100081 辽宁省检验检测认证中心辽宁沈阳110036 江西省农业技术推广中心江西南昌330046 北京林业大学经济管理学院北京100083

胆汁酸是胆固醇的末端代谢物,具有调控机体糖脂代谢、能量代谢及免疫应答等生理作用,因此,作为一种新型饲料添加剂被广泛应用于动物养殖。本文对胆汁酸的生理功能及其在家禽、生猪、水产和其他动物养殖中的应用现状进行综述,以期为外源... 详细信息

胆汁酸是胆固醇的末端代谢物,具有调控机体糖脂代谢、能量代谢及免疫应答等生理作用,因此,作为一种新型饲料添加剂被广泛应用于动物养殖。本文对胆汁酸的生理功能及其在家禽、生猪、水产和其他动物养殖中的应用现状进行综述,以期为外源性胆汁酸添加提供参考。

关键词：胆汁酸饲料添加剂畜牧业水产养殖

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基于APRI和PALBI构建的列线图对肝硬化并发食管胃底静脉曲张破裂出血的预测价值

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临床肝胆病杂志 2024年第3期40卷 521-526页

作者：李欣忆李娇娇李莹莹魏虹合熊雨凡张新驰孙蔚陈丽苏州大学附属第一医院感染科江苏苏州215000

目的评估天冬氨酸转氨酶与血小板比值指数(APRI)和血小板-白蛋白-胆红素评分(PALBI)对肝硬化并发食管胃底静脉曲张破裂出血风险的预测价值。方法选取苏州大学附属第一医院于2021年5月—2022年6月收治的肝硬化患者119例,收集患者的临... 详细信息

目的评估天冬氨酸转氨酶与血小板比值指数(APRI)和血小板-白蛋白-胆红素评分(PALBI)对肝硬化并发食管胃底静脉曲张破裂出血风险的预测价值。方法选取苏州大学附属第一医院于2021年5月—2022年6月收治的肝硬化患者119例,收集患者的临床资料、血常规、血清生化及血凝等检查结果。根据是否合并食管胃底静脉曲张破裂出血,将患者分为未出血组(n=59)和出血组(n=60),比较组间差异。正态分布的计量资料两组间比较采用独立样本t检验,非正态分布的计量资料两组间比较采用Mann-Whitney U检验。计数资料组间比较采用χ^(2)检验或Fisher精确概率法。使用多因素Logistic回归分析,筛选肝硬化并发食管胃底静脉曲张破裂出血的独立危险因素,并构建列线图预测模型。结果出血组男性患者占75.00%,未出血组男性患者占40.68%,两组在性别构成方面,差异具有统计学意义(χ^(2)=14.384,P<0.001)。出血组和未出血组患者病因均以慢性乙型肝炎为主(53.33%vs 38.98%),两者构成比差异无统计学意义(χ^(2)=2.464,P=0.116)。出血组患者抗凝血酶原Ⅲ活性(AT-IIIA)水平高于未出血组(t=3.329,P=0.001),PLT、TBil、Ca、TC、TT水平则低于未出血组(P值均<0.05)。APRI和PALBI在出血组和未出血组之间比较,差异均有统计学意义(χ^(2)值分别为6.175、19.532,P值均<0.05)。进一步二元Logistic回归分析发现,APRI(OR=0.309,95%CI:0.109~0.881,P=0.028)、PALBI(OR=7.667,95%CI:2.005~29.327,P=0.003)、Ca(OR=0.001,95%CI:0.000~0.141,P=0.007)、TC(OR=0.469,95%CI:0.226~0.973,P=0.042)和TT(OR=0.599,95%CI:0.433~0.830,P=0.002)是影响肝硬化并发食管胃底静脉曲张破裂出血的独立影响因素。基于以上因素建立列线图模型,一致性指数(C-index)为0.899,校准曲线拟合良好。结论 APRI及PALBI对肝硬化并发食管胃底静脉曲张破裂出血具有良好的预测价值,基于本研究构建的列线图模型可以个体化预测肝硬化患者食管胃底静脉曲张破裂出血发生率。

关键词：肝硬化食管和胃静脉曲张胃肠出血 APRI PALBI 列线图

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Motivating Ru-bri site of RuO_(2)by boron doping toward high performance acidic and neutral oxygen evolution

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Nano Research 2022年第8期15卷 7008-7015页

作者： Chongjing Liu Beibei Sheng Quan Zhou Dengfeng Cao honghe Ding Shuangming chen Pengjun Zhang Yujian Xia Xiaojun Wu Li Song National Synchrotron Radiation Laboratory CAS Center for Excellence in NanoscienceUniversity of Science and Technology of ChinaHefei 230029China Institute of Energy Hefei Comprehensive Nation Science CenterHefei 230031China Hefei National Laboratory for Physical Sciences at the Microscales Department of Materials Sciences and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

The electrocatalysis of oxygen evolution reaction(OER)plays a key role in clean energy storage and transfer.Nonetheless,the sluggish kinetics and poor durability under acidic and neutral conditions severely hinder practical applications such as electrolyzer compatible with the powerful proton exchange membrane and biohybrid fuel production.Here,we report a borondoped ruthenium dioxide electrocatalyst(B-RuO_(2))fabricated by a facile boric acid assisted strategy which demonstrates excellent acidic and neutral OER performances.Density functional theory calculations and advanced characterizations reveal that the boron species form an anomalous B–O covalent bonding with the oxygen atoms of RuO_(2)and expose the fully coordinately bridge ruthenium site(Ru-bri site),which seems like a switch that turns on the inactive Ru-bri site into OER-active,resulting in more exposed active sites,modified electronic structure,and optimized binding energy of intermediates.Thus,the B-RuO_(2)exhibits an ultralow overpotential of 200 mV at 10 mA/cm^(2)and maintains excellent stability compared to commercial RuO_(2)in 0.5 M sulfuric acid.Moreover,the superior performance is as well displayed in neutral electrolyte,surpassing most previously reported catalysts.

关键词： acidic and neutral oxygen evolution reaction RuO_(2) boron doping the fully coordinately bridge ruthenium site(Ru-bri site) density functional theory

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拟制亲属与家观念延续:以红河南岸哈尼族为例

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原生态民族文化学刊 2024年第4期16卷 118-127,156页

作者：陈民炎云南大学西南边疆少数民族研究中心昆明650091

拟制亲属关系是很多西南民族实现家与社会延续的重要手段之一,通过拟制血亲来确认本家与被认对象之间的亲缘关系,继而实现家观念的延续以及地方社会整合。红河南岸哈尼族选择拟制血亲的内生动力在于:本家父子连名制度的延续、土地房屋... 详细信息

拟制亲属关系是很多西南民族实现家与社会延续的重要手段之一,通过拟制血亲来确认本家与被认对象之间的亲缘关系,继而实现家观念的延续以及地方社会整合。红河南岸哈尼族选择拟制血亲的内生动力在于:本家父子连名制度的延续、土地房屋等物质财富、房屋守护神祇灵力、祖先灵力的继承以及完成仪式上的道德义务与责任。

关键词：家观念拟制亲属红河南岸哈尼族

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Devonian integrative stratigraphy and timescale of China

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Science China Earth Sciences 2019年第1期62卷 112-134页

作者： Wenkun QIE Xueping MA honghe XU Li QIAO Kun LIANG Wen GUO Junjun SONG Bo chen Jianfeng LU CAS Key Laboratory of Economic Stratigraphy and Palaeogeography Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and Paleoenvironment Chinese Academy of Sciences School of Earth and Space Sciences Peking University State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and Paleoenvironment Chinese Academy of Sciences Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and Paleoenvironment Chinese Academy of Sciences

The Global Boundary Stratotype Sections and Points(GSSPs) for the bases of all seven international Devonian stages have been formally defined and ratified by IUGS till 1996, and nowadays, the main tasks for Devonian stratigraphers include further subdivision of these standard stages, strictly constrained absolute ages for the boundaries, and precise neritic-pelagic and marine-terrestrial correlations using multidisciplinary stratigraphy methods. Establishment of high-resolution Devonian integrative stratigraphy framework and timescale of China would play an important role in improving regional and international correlation, facilitating the recognition of important stratigraphic levels in different paleogeographic settings, and understanding the evolution pattern of biota, paleoclimate and paleoenvironment during this critical interval. Based on well-studied bio-and chronostratigraphy of Devonian in South China and adjacent areas, in combination with recent achievements in carbon isotope stratigraphy, event stratigraphy and radioactive isotope ages, this paper briefly summarize the research history and current status of Devonian chronostratigraphy of China, and for the first time introduce Devonian integrative stratigraphy framework of China.Up to date, few studies have been conducted on the astronomical cyclostratigraphy and high-resolution radioactive isotope dating in Devonian of China, which should be our main focuses in the near future.

关键词： Devonian Chronostratigraphy Biostratigraphy Carbon isotope stratigraphy Event stratigraphy

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