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Clinical validation of the early embryo viability assessment system: Analysis for the blastocyst morphology and pregnancy outcomes

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Asian pacific Journal of Reproduction 2024年第5期13卷 219-227页

作者： vu D Hop An M Cuong Phi t t Anh Nguyen t L Huong Le Hoang Nguyen V Hanh Assisted Reproductive technology Centre Tam Anh General HospitalHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:to determine the relationship between the early embryo viability assessment(EEVA)and blastocyst morphological parameters and pregnancy ***:this retrospective cohort study was conducted on 291 intracytoplasmic sperm injection cycles including 2522 embryos with indications of prolonging embryo culture to the blastocyst stage in the Genea embryo review incubator,and 511 single vitrified-warmed blastocyst transfer cycles from January 2020 to June *** EEVA system produced an EEVA score from E1(best)to E5(worse)for the potential of blastocyst *** morphology was *** association between the EEVA score and each type of blastocyst morphology,implantation rate,clinical pregnancy,and ongoing pregnancy were assessed using generalized estimating ***:the inner cell mass A(ICM A),trophectoderm A(tE A),blastocoele expansion degree of 3,4,5,6,7 rates were higher with lower the EEVA *** adjusted odd ratio(aOR)(E5 vs E1)was 0.3 for ICM A,0.174 for tE A and 0.210 for BL3,4,5,6,7(all Pting a significant association between lower EEVA scores and improved embryo *** implantation,clinical pregnancy,and ongoing pregnancy rate were also higher with lower the EEVA *** aOR of E5 vs E1 was 0.245 for implantation,0.185 for clinical pregnancy and 0.200 for ongoing pregnancy rate(Pthere were associations between blastocyst morphology,pregnancy outcome and EEVA *** good blastocyst morphology and pregnancy outcomes are higher with lower the EEVA score.

关键词： Automated embryo assessment Blastocyst Early embryo viability assessment Genea embryo review incubator

Enhanced urban functional land use map with free and open-source data

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International Journal of Digital Earth 2021年第11期14卷 1744-1757页

作者： t.t.vu N.V.A.vu H.P.Phung L.D.Nguyen Faculty of Engineering and Science Curtin University MalaysiaMiriMalaysia Vietnam National Space Center Vietnam Academy of Science and Technology(VAST)Ho Chi Minh cityVietnam

the study aims at developing an applicable methodology to produce the functional land-use map using only free and open-source ***-view Sentinel image and ground-view Open Street Map(OSM)data are chosen due to their extensive *** three-stage framework,including object-based image analysis,OSM data cleaning,and ontology-based decision fusion,is proposed and implemented with open-source *** applied the developed approach to districts 1,4,and 7 of HoChiMinh city,representing the complexities of the dynamic change in big *** result showed a good functional land use map with 78.70%overall *** outcome presents the mismatch between the data-driven approach and human knowledge,which can be improved by ontology-based fusion with OSM *** ontology-based framework comprises the common urban land-use classes and OSM attributes,which can be applied and extended in other urban *** text attributes may be applicable only locally and can be modified in our open-source ***-based image analysis takes advantage of Google Earth Engine computing power,whereas ontology-based processing works well on a local *** future studies,adopted natural language processing to pre-process OSM data and ontology-based fusion will be implemented on the cloud-computing platform to enhance computational efficiency.

关键词： Data fusion Remote Sensing Digital City Land use GIS

Bubble-enhanced quadrilateral finite element formulation for nonlinear analysis of geotechnical problems

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Underground Space 2018年第3期3卷 229-242页

作者： t.vu-Hoang t.Vo-Minh H.Nguyen-Xuan Department of Civil Engineering HCMC University of TechnologyHo Chi Minh CityViet Nam Department of Civil Engineering Hutech UniversityHo Chi Minh CityViet Nam Center for Interdisciplinary Research in technology Hutech UniversityHo Chi Minh CityViet Nam

We investigate a new numerical procedure based on a bubble-enriched finite element formulation in combination with the implicit backward Euler scheme for nonlinear analysis of strip footings and stability of *** soil body is modeled as a perfect plastic Mohr-Coulomb *** displacement field is approximated by a 4-node quadrilateral element discretization enhanced with bubble *** loads and failure mechanisms in cohesive frictional soil are determined by solving a few Newton-Raphson *** results of the present approach are verified by both analytical solutions and other numerical solutions available in the literature.

关键词： Material nonlinear analysis Backward Euler scheme Bearing capacity Slope stability Bubble functions Finite elements

Robust exponential stability and stabilization of linear uncertain polytopic time-delay systems

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控制理论与应用（英文版） 2008年第2期6卷 163-170页

作者： Nam PHAN t. Phat vu N. Department of Mathematics Quynhon UniversityQuynhonBinhdinhVietnam Institute of Mathematics 18 Hoang Quoc Viet RoadHanoiVietnam

this paper proposes new sufficient conditions for the exponential stability and *** linear uncertain polytopic time-delay systems. the conditions for exponential stability are expressed in terms of Kharitonov-type linear matrix inequalities （LMIs） and we develop control design methods based on LMIs for solving stabilization problem. Our method consists of a combination of the LMI approach and the use of parameter-dependent Lyapunov functionals, which allows to compute simultaneously the two bounds that characterize the exponetial stability rate of the solution. Numerical examples illustrating the conditions are given.

关键词： Polytopic time-delay system Exponential stability Stabilization Parameter-dependent Lyapunov function Linear matrix inequalities

Hydrogeological Characteristics of a Karst Mountainous Catchment in the Northwest of Vietnam

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Acta Geologica Sinica(English Edition) 2001年第3期75卷 260-268页

作者： V.t.tAM t.M.N.vu O.BAtELAAN Research Institute of Geology and Mineral Resources Ministry of Industry VietnamResearch Institute of Geology and Mineral Resources Ministry of Industry VietnamDepartment of Hydrology and Hydraulic Engineering Free University Brussels Belgium

this paper presents a preliminary assessment of the hydrogeological characteristics of a karst mountainous catchment, the Suoi Muoi River catchment, in the northwest of Vietnam. the catchment is located at 600–700 m a.s.l. and covers an area of 284 km. Exposed limestone occupies 32% of the total catchment area. Various types of assessments have been carried out, including geological and hydrogeological field surveys, cave surveys, dye-tracer tests, meteorological and surface water monitoring. Geological studies and cave surveys have identified the most important active cave/conduit systems within the catchment. Although these data are essential, they are insufficient to make a comprehensive appraisal of the hydrologic nature of the catchment under interest. An attempt was made to calculate a global water balance of the catchment, based on short-term (15 months) meteorological and streamflow records. the results show that, despite the existence of a number of substantial cavern conduit systems, the groundwater system of the catchment is governed by the fracture/fissure matrix. the cavern conduit systems only collect groundwater from the adjacent fracture matrix and/or connect topographically isolated surface watercourses. the groundwater storage of the cavern conduit systems appears to be regionally insignificant in comparison with the governed fracture matrix groundwater system.

关键词： karst hydrology geology lowflow

Polygonal Finite Element for two-Dimensional Lid-Driven Cavity Flow

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Computers, Materials & Continua 2022年第3期70卷 4217-4239页

作者： t.vu-Huu C.Le-thanh H.Nguyen-Xuan M.Abdel-Wahab Faculty of Civil Engineering Vietnam Maritime University484 Lach Tray Str.Hai PhongVietnam Faculty of Civil Engineering and Electricity Ho Chi Minh City Open UniversityVietnam CIRtech Institute Ho ChiMinh City University of Technology(HUTECH)Ho Chi Minh CityVietnam Department of Architectural Engineering Sejong University209 NeungdongroGwangjinguSeoul05006Republic of Korea Soete Laboratory Faculty of Engineering and ArchitectureGhent UniversityTechnologiepark Zwijnaarde903B-9052ZwijnaardeBelgium

this paper investigates a polygonal finite element(PFE)to solve a two-dimensional(2D)incompressible steady fluid problem in a cavity *** is a well-known standard benchmark(i.e.,lid-driven cavity flow)-to evaluate the numerical methods in solving fluid problems controlled by the Navier-Stokes(N-S)equation *** approximation solutions provided in this research are based on our developed equal-order mixed PFE,called *** is an exciting development based on constructing the mixed scheme method of two equal-order discretisation spaces for both fluid pressure and velocity fields of flows and our proposed stabilisation *** this research,to handle the nonlinear problem of N-S,the Picard iteration scheme is *** proposed method’s performance and convergence are validated by several simulations coded by commercial software,i.e.,*** this research,the benchmark is executed with variousReynolds numbers up to the maximum Re=*** results then numerously compared to available sources in the literature.

关键词： Lid-driven cavity incompressible steady Navier-Stokes equations polygonal finite element method

Stabilization for Equal-Order Polygonal Finite Element Method for High Fluid Velocity and Pressure Gradient

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Computers, Materials & Continua 2020年第3期62卷 1109-1123页

作者： t.vu-Huu C.Le-thanh H.Nguyen-Xuan M.Abdel-Wahab Department of Electrical energy MetalsMechanical Constructions and SystemsFaculty of Engineering and ArchitectureGhent UniversityGhentBelgium Faculty of Civil Engineering Vietnam Maritime UniversityHai PhongVietnam Faculty of Civil Engineering and Electricity Ho Chi Minh City Open UniversityHo Chi MinhVietnam CIRtech Institute Ho Chi Minh City University of Technology(HUTECH)Ho Chi MinhVietnam Division of Computational Mechanics Ton Duc Thang UniversityHo Chi MinhVietnam Faculty of Civil Engineering Ton Duc Thang UniversityHo Chi MinhVietnam

this paper presents an adapted stabilisation method for the equal-order mixed scheme of finite elements on convex polygonal meshes to analyse the high velocity and pressure gradient of incompressible fluid flows that are governed by Stokes equations *** technique is constructed by a local pressure projection which is extremely simple,yet effective,to eliminate the poor or even non-convergence as well as the instability of equal-order mixed polygonal *** this research,some numerical examples of incompressible Stokes fluid flow that is coded and programmed by MAtLAB will be presented to examine the effectiveness of the proposed stabilised method.

关键词： Polygonal finite element method fluid computation stokes equation mixed method local projection

Clinical outcomes of patients with chronic hepatitis C after generic direct-acting antiviral treatments in Vietnam: A retrospective analysis

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Asian Pacific Journal of tropical Medicine 2020年第11期13卷 487-493页

作者： Huong tt vu Azumi Ishizaki Quynh t Nguyen Huyen N Nguyen Hoi t Le Kinh V Nguyen Hiroshi Ichimura National Hospital for tropical Disease HanoiVietnam Department of Viral Infection and International Health Graduate School of Medical SciencesKanazawa UniversityJapan

Objective:to evaluate the outcomes of generic direct-acting antiviral treatments for chronic hepatitis C in ***:the medical records of 522 patients(median 45 years;Female,25.3%)with chronic hepatitis C treated at a tertiary hospital in northern Vietnam in 2016 were retrospectively ***:Female patients were significantly older than male patients(median 52,IQR 41-59 vs.43 years,IQR:39-55;Ptients,49.4%were infected with hepatitis C virus(HCV)genotype 6,followed by 1 a(19.0%),1 b(13.0%),and 3(5.9%).Coinfection with hepatitis B virus or human immunodeficiency virus was noted in 5.8%and 3.1%of patients,*** were treated with ledipasvir/sofosbuvir with or without ribavirin(70.9%),sofosbuvir/pegylated-interferon+ribavirin(13.2%),daclatasvir/sofosbuvir with or without ribavirin(12.5%),or sofosbuvir/ribavirin(3.4%),and 96.4%(n=503)completed the direct-acting antiviral *** patient discontinued treatment due to adverse event(s).A sustained virologic response 12 weeks after the end of the treatment(SVR12)was evaluated in 62.6%of *** sustained virologic response 12 weeks after the end of the treatment was 98.7%regardless of HCV genotypes or direct-acting antiviral *** severity of liver stiffness was significantly decreased from 10.2 to 6.3 kilopascals measured by transient elastography by the treatment(Ptients who completed the directacting antiviral treatment,17.7%returned for further follow-ups after ***:In Vietnam,the current generic direct-acting antiviral treatment for chronic hepatitis C was effective regardless of HCV genotypes and direct-acting antiviral regimens with the attenuation of liver *** is feasible to implement direct-acting antiviral treatment to cure chronic hepatitis C patients at any liver fibrosis stages in Vietnam.

关键词： Vietnam Chronic hepatitis C Generic direct-acting antiviral Improvement of liver stiffness

Role of CD97^(stalk) and CD55 as molecular markers for prognosis and therapy of gastric carcinoma patients

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2005年第9期6卷 913-918页

作者：柳咏陈力彭淑牖陈周浔 HOANG-vu C Department of Surgery Second Affiliated Hospital School of Medicine Yangzhou University Yangzhou 225001 China Department of Surgery Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China Department of Surgery Second Affiliated Hospital School of Medicine Zhejiang UniversityHangzhou 310009 China Department of Surgery University of Halle-WittenbergHalle Germany

Objectives： to explore the mechanism of development and aggressiveness in gastric carcinomas by investigating the expression and role of CD97 and its cellular ligand CD55 in gastric carcinomas. Methods： tumor and corresponding normal mucosal tissue, collected from 39 gastric carcinoma patients, were examined by immunohistochemistry and Rt-PCR for the expression of CD97 and CD55. Results： CD97^stalk was strongly stained on scattered tumor cells or small tumor cell clusters at the invasion front of gastric carcinomas. the expression of CD97^stalk was frequently observed in tumors of stage Ⅰ and t1 gastric carcinoma patients. the expression of CD97^stalk between Stage Ⅰ and Stage Ⅱ, Ⅲ, Ⅳ specimens showed significant difference （P〈0.05）, between t1 and t2, t3, t4 specimens also showed significant difference （P〈0.05）. Specimens with tumor invasion depth limited in mucosa of t1 specimens showed higher positive CD55 expression than specimens with the same tumor invasion depth in t2, t3, t4 specimens, the expression of CD55 between t1 and t2, t3, t4 specimens was significantly different （P〈0.05）. there was strong correlation between the distribution patterns of CD97^stalk and CD55 on tumor tissues （r=0.73, P〈0.05）. Signet ring cell carcinomas frequently contained strong CD97^stalk and CD55-staining. Conclusions： Our results suggest that CD97^stalk is probably involved in the growth, invasion and aggressiveness of gastric carcinomas by binding its cellular ligand CD55. CD97^stalk and CD55 could be useful as molecular markers for prognosis and therapy of gastric carcinoma patients.

关键词： CD97^stalk CD55 Gastric carcinoma Molecular markers