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The relationship between thermo-mechanical history,microstructure and mechanical properties in additively manufactured CoCrFeMnNi high entropy alloy

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Journal of Materials Science & Technology 2021年第18期77卷 187-195页

作者： hongge li Yongjiang Huang Jianfei Sun Yunzhuo Lu School of Materials Science and Engineering Harbin Institute of TechnologyHarbinChina School of Materials Science and Engineering Dalian Jiaotong UniversityDalianChina

Here,a single-track CoCrFeMnNi high entropy alloy(HEA)was successfully fabricated by laser melting deposition(LMD).Combining the experimental observations and numerical simulation,the microstructure and mechanical properties of the as-deposited parts were systematically studied from the perspective of thermo-mechanical history experienced during the LMD *** strengthening mechanisms of the LMDed CoCrFeMnNi HEA parts were *** frictional stress strengthening,grain boundary strengthening and dislocation strengthening contributed the whole yield strength of the *** strengthening dominated the strengthening *** was expected that the establishment of the relationship between thermo-mechanical history,microstructure and mechanical properties of the LMDed CoCrFeMnNi HEA could shed more insights into achieving HEA parts with the desired microstructure and high performance.

关键词： Laser melting deposition High entropy alloy Thermo-mechanical history Microstructure Mechanical property Strengthening mechanisms

Aluminum exposure impairs oocyte quality via subcellular structure disruption and DNA damage-related apoptosis in mice

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Journal of Environmental Sciences 2024年第5期139卷 308-319页

作者： hongge li Jingcai liu Weihua Nong Mengying Shen Sheng Dou Shaochen Sun Junli Wang The Affiliated Hospital of Youjiang Medical University for Nationalities Guangxi 533000China College of Animal Science and Technology Nanjing Agricultural UniversityNanjing 210095China School of Medical Laboratory Youjiang Medical University for NationalitiesGuangxi 533000China Industrial College of Biomedicine and Health Industry Youjiang Medical University for NationalitiesGuangxi 533000China Reproductive Medicine Guangxi Medical and Health Key Discipline Construction ProjectThe Affiliated Hospital of Youjiang Medical University for NationalitiesGuangxi 533000China

Aluminum(Al)can lead to an exposure of creature in varieties ways for its universality,and it could disturb normal physiological metabolism,with the damage to multisystem including *** the oocyte quality is critical for female reproduction,we inspected the toxicity of Al on mouse oocyte *** constructed in vitro exposure mouse model,and we found that 5 mmol/L Al had adverse effects on oocyte maturation by impairing organelle and *** spindle and misaligned chromosomes which might be considered to be caused by elevated levels of acetylation,as well as abnormal distribution of actin dynamics could hinder normal meiosis of *** dysfunction indicated that Al affected proteins synthesis,transport and digestion,which would further damage oocyte *** order to explore the mechanism of Al toxicity,our further investigation demonstrated that Al caused mitochondrial dysfunction and imbalance calcium homeostasis,resulting in limited energy ***,high level of reactive oxygen species,DNA damage and apoptosis caused by oxidative stress were also the manifestation of Al toxicity on *** conclusion,our study provided the evidence that Al exposure affected oocyte quality through its effects on spindle organization,actin dynamics,organelle function and the induction of DNA damage-related apoptosis with mouse model.

关键词： Aluminum Oocyte Cytoskeleton Organelle DNA damage

Increased Neuronal Hypoxic Tolerance Induced by Repetitive Chemical Hypoxia

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2002年第2期22卷 132-134页

作者： li hongge(李红戈) liU Chngqin(刘昌勤) SUN Shenggang(孙圣刚) Department of Neurology Xiehe Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Department of Neurology Xiehe Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Department of Neurology Xiehe Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022

Summary: To investigate the effects of time interval and cumulative dosage of repetitive mild cellular hypoxia on shape of neurodegeneration and neuroprotection in mice, population spike amplitude (PSA) was measured during hypoxia and posthypoxic recovery in hippocampal slices from untreated control and mice pretreated in vivo with a single or repeatedly intraperitoneal injection of 3-nitropropionate (3-NP). Posthypoxic recovery of PSA was dose-dependent in single pretreated slices, with maximal recovery on pretreatment attained with 20 mg/kg 3-NP (82±32%, P< 0.01). Upon 5 and 9 treatments with 20 mg/kg 3-NP (dosage interval 3 days), PSA recovered to (38±9) % with the difference being not significant vs control group and (72±45) % with the difference being significant (P< 0.05 to control, P<0.05 to 5 treatments), respectively. In contrast, with 2 days time interval, recovery after 5 and 9 treatments was (30±25) % and (16±14) %, respectively (without significant difference from control). Continued neuroprotection was also observed upon increase of dosage interval to 4 and 5 days. It was suggested that repetitive chemical hypoxia is a model for neurodegenerative disease and continued neuroprotection depending on time interval between repetitive hypoxic episodes rather than cumulative dosage. At appropriate time intervals increased neuronal hypoxic tolerance could be induced with number of hypoxic episodes.

关键词： hypoxia electrophysiology Huntington's disease 3-nitropropionate

Genomic insight into the divergence and adaptive potential of a forgotten landrace *** ***

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Journal of Genetics and Genomics 2021年第6期48卷 473-484页

作者： Mian Faisal Nazir Shoupu He Haris Ahmed Zareen Sarfraz Yinhua Jia hongge li Gaofei Sun Muhammad Shahid Iqbal Zhaoe Pan Xiongming Du State Key Laboratory of Cotton Biology Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyangHenan 455000China School of Agricultural Sciences Zhengzhou UniversityZhengzhouHenan 450001China Cotton Research Institute Ayub Agricultural Research InstituteMultan 60000Pakistan Research Base State Key Laboratory of Cotton BiologyZhengzhou UniversityZhengzhouHenan 450001China

Wild progenitors are an excellent source for strengthening the genetic basis and accumulation of desirable variation lost because of directional selection and adaptation in modern ***,we re-evaluate a landrace of Gossypium hirsutum,formerly known as Gossypium *** study seeks to understand the genomic structure,variation,and breeding potential of this landrace,providing potential insights into the biogeographic history and genomic changes likely associated with domestication.A core set of accessions,including current varieties,obsolete accessions,***,and other geographical landraces,are subjected to genotyping along with multilocation *** fixation statistics suggests a marked differentiation between *** and three other groups,emphasizing the divergent genomic behavior of *** analysis establishes the primitive nature of ***,identifying it as a vital source of functional variation,the inclusion of which in the upland cotton(cultivated ***)gene pool may broaden the genetic basis of modern ***-wide association results indicate multiple loci associated with domestication regions corresponding to flowering and fiber ***,the conserved nature of *** can also provide insights into the evolutionary process of ***.

关键词： Gossypium purpurascens Upland cotton Genetic differentiation G.hirsutum Domestication

Genetic dissection and origin of pleiotropic loci underlying multilevel fiber quality traits in upland cotton(Gossypium hirsutum L.)

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Journal of Integrative Agriculture 2024年第10期23卷 3250-3263页

作者： hongge li Shurong Tang Zhen Peng Guoyong Fu Yinhua Jia Shoujun Wei Baojun Chen Muhammad Shahid Iqbal Shoupu He Xiongming Du Zhengzhou Research Base State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/School of Agricultural SciencesZhengzhou UniversityZhengzhou 450001China State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/Institute of Cotton Research Chinese Academy of Agricultural SciencesAnyang 455000China

Cotton fiber quality is a persistent concern that determines planting benefits and the quality of finished textile ***,the limitations of measurement instruments have hindered the accurate evaluation of some important fiber characteristics such as fiber maturity,fineness,and neps,which in turn has impeded the genetic improvement and industrial utilization of cotton ***,12 single fiber quality traits were measured using Advanced Fiber Information System(AFIS)equipment among 383 accessions of upland cotton(Gossypium hirsutum L.).In addition,eight conventional fiber quality traits were assessed by the High Volume Instrument(HVI)***-wide association study(GWAS),linkage disequilibrium(LD)block genotyping and functional identification were conducted sequentially to uncover the associated elite loci and candidate genes of fiber quality *** a result,the previously reported pleiotropic locus FL_D11 regulating fiber length-related traits was identified in this *** importantly,three novel pleiotropic loci(FM_A03,FF_A05,and FN_A07)regulating fiber maturity,fineness and neps,respectively,were detected based on AFIS *** highly promising candidate genes were screened out by integrating RNA-seq and qRT-PCR analyses,including the reported GhKRP6 for fiber length,the newly identified GhMAP8 for maturity and GhDFR for *** origin and evolutionary analysis of pleiotropic loci indicated that the selection pressure on FL_D11,FM_A03 and FF_A05 increased as the breeding period approached the present and the origins of FM_A03 and FF_A05 were traced back to cotton *** findings reveal the genetic basis underlying fiber quality and provide insight into the genetic improvement and textile utilization of fiber in ***.

关键词： upland cotton single fiber quality pleiotropic loci candidate genes locus origin

Beneficial effects of deep cryogenic treatment on mechanical properties of additively manufactured high entropy alloy:cyclic vs single cryogenic cooling

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Journal of Materials Science & Technology 2022年第20期115卷 40-51页

作者： hongge li Wenjie Zhao Tian Chen Yongjiang Huang Jianfei Sun Ping Zhu Yunzhuo Lu Alfonso H.W.Ngan Daqing Wei Qing Du Yongchun Zou School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China School of Materials Science and Engineering Dalian Jiaotong UniversityDalian 116028China Department of Mechanical Engineering The University of Hong KongHong KongChina Center of Analysis Measurement and Computing Harbin Institute of TechnologyHarbin 150001China

Additively manufactured(AM)metallic materials commonly possess substantial tensile surface residual stress,which is detrimental to the load-bearing service ***,we demonstrated that deep cryogenic treatment(DCT)is an effective method for improving the tensile properties of CoCrFeMnNi high-entropy alloy(HEA)samples fabricated by laser melting deposition(LMD),by introducing high compressive residual stress and deformation microstructures without destroying the AM ***,carrying out the DCT in a single-step mode does not improve the residual stress gradients inherent from the LMD process,which are undesirable as the mechanical properties will not be homogeneous within the *** this work,we show that carrying out the DCT in a cyclic mode with repeated cryogenic cooling and reheating can significantly homogenize the residual stress in LMD-fabricated Co Cr Fe Mn Ni HEA,and improve tensile strength and ductility,compared with single-step DCT of the same cryogenic soaking *** cyclic DCT,the thermal stress is re-elevated to a high value at each cryogenic cooling step,leading to the formation of denser and more intersecting reinforcing crystalline defects and hcp phase transformation,compared to single-step DCT of the same total cryogenic soaking duration in which the thermal stress relaxes towards a low value over *** enhancement of defect formation in the cyclic mode of DCT also leads to more uniform residual stress distribution in the sample after the *** results here provide important insights on optimizing DCT processes for post-fabrication improvement of mechanical properties of AM metallic net shapes.

关键词： Additive manufacturing High entropy alloy Deep cryogenic treatment Residual stress Mechanical properties

QTL mapping of agronomic and economic traits for four F_(2)populations of upland cotton

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Journal of Cotton Research 2021年第1期4卷 12-23页

作者： li hongge PAN Zhaoe HE Shoupu JIA Yinhua GENG Xiaoli CHEN Baojun WANG liru PANG Baoyin DU Xiongming State Key Laboratory of Cotton Biology/Institute of Cotton Research Chinese Academy of Agricultural SciencesAnyangHenan 455000China

Background:Upland cotton(Gossypium hirsutum)accounts for more than 90%of the annual world cotton output because of its high yield ***,yield and fiber quality traits often show negative *** constructed four F_(2)populations of upland cotton,using two normal lines(4133B and SGK9708)with high yield potential but moderate fiber quality and two introgression lines(Suyuan04–3 and J02–247)with superior fiber quality,and used them to investigate the genetic basis underlying complex traits such as yield and fiber quality in upland *** also phenotyped eight agronomic and economic traits and mapped quantitative trait loci(QTLs).Results:Extensive phenotype variations and transgressive segregation were found across the segregation *** constructed four genetic maps of 585.97 centiMorgan(cM),752.45 cM,752.45 cM,and 1163.66 cM,one for each of the four F_(2)*** QTLs were identified across the four populations(7 for plant height,27 for fiber quality and 16 for yield).The same QTLs were identified in different populations,including qBW4 and qBW2,which were linked to a common simple sequence repeat(SSR)marker,NAU1255.A QTL cluster containing eight QTLs for six different traits was characterized on linkage group 9 of the 4133B×Suyuan04–3 ***:These findings will provide insights into the genetic basis of simultaneous improvement of yield and fiber quality in upland cotton breeding.

关键词： Upland cotton Yield traits Fiber quality traits QTL mapping Simultaneous improvement

Identification and expression analysis of Tubulin gene family in upland cotton

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Journal of Cotton Research 2021年第3期4卷 229-238页

作者： CHEN Baojun ZHAO Junjie FU Guoyong PEI Xinxin PAN Zhao'e li hongge AHMED Haris HE Shoupu DU Xiongming State Key Laboratory of Cott on Biology Institute of Cotton ResearchChinese Academy of Agricultural Sciences(ICRCAAS)Anyang 455000China

Background:Cott on fibers are single-celled exte nsions of the seed epidermis,a model tissue for studying *** genes play a critical role in synthesizing the microtubules(MT)as a core element of the ***,there is a lack of studies concerning the systematic characterization of the tubulin gene family in ***,the identification and portrayal of *** tubulin genes can provide key targets for molecular manipulation in cotton ***:In this study,we investigated all tubulin genes from different plant species and identified 98 tubulin genes in *** an a lysis showed that tubulin family genes were classified into three *** protein motifs and gene structure ofβ-tubulin genes are more conserved compared withγ-tubulin *** tubulin genes are located at the proximate ends of the *** expression pattern by transcriptome and qRT-PCR analysis revealed that 12α-tubulin andβ-tubulin genes are specifically expressed during different fiber development ***,Gh.A03G027200,Gh.D03G 169300,and Gh.A1lG258900 had differential expression patterns at distinct stages of fiber development in varieties JO2508 and ***:In this study,the evol ut io nary an alysis showed that the tubulin genes were divided into three *** genetic structures and molecular functions were highly con served in different *** candidate genes,Gh.A03G027200f Gh.D03G169300,and Gh.A11G258900 may play a key role during fiber development complementing fiber length and strength.

关键词： Upland cotton Fiber quality Cytoskeleton Microtubules(MT) Tubulin

A tradeoff between on and off current for armchair graphene nanoribbon field effect transistors explained by the complex band structure

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A tradeoff between on and off current for armchair graphene ...