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Food Bioscience 2022年第5期49卷 853-862页

作者： hongbing fan Kaiyu Wu Jianping Wu Department of Agricultural Food and Nutritional Science4-10 Ag/For BuildingUniversity of AlbertaEdmontonAlbertaT6G 2P5Canada Cardiovascular Research Centre University of AlbertaEdmontonAlbertaT6G 2R7Canada

Leu-Arg-Trp(LRW),a pea-derived tripeptide,is an isomer of Ile-Arg-Trp(IRW),an egg-derived tripeptide possessing various health benefits including antihypertensive *** LRW and IRW are structural analogs,we hypothesized that LRW can significantly reduce blood pressure in spontaneously hypertensive *** showed a more potent in vitro ACE-inhibitory activity(IC50 value of 0.45±0.06μM)than that of IRW(1.65±0.14μM);molecular docking results also verified that LRW could form a more stable complex with ACE than that of *** addition,LRW could inhibit tumor necrosis factor alpha-induced endothelial inflammation in similar manners to ***,oral administration of LRW at a dose of 15 mg/kg/day body weight over 12 days did not cause any blood pressure reduction(p>0.05).Subsequent tissue analyses revealed no changes in the vascular renin-angiotensin system components and vascular inflammation,which are the primary targets of IRW,indicating that LRW might not be able to reach the blood circulation and exert in vivo ***,LRW demonstrated significantly lower gastrointestinal stability(p<0.001)and lower permeability(p<0.001)across human Caco-2 cell monolayers than those of *** findings indicated the low oral bioavailability of LRW which might underlie its failure in reducing blood pressure in vivo.

关键词： Pea ACE Caco-2 cells Endothelial inflammation Gastrointestinal digestion Molecular docking Spontaneously hypertensive rats

Effect of simulated gastrointestinal digestion on antioxidant,and anti-inflammatory activities of bioactive peptides generated in sausages fermented with Staphylococcus simulans QB7

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Food Science and Human Wellness 2024年第3期13卷 1662-1671页

作者： Hongying Li hongbing fan Zihan Wang Qiujin Zhu Jianping Wu Laboratory of Animal Genetics Breeding and Reproduction in the Plateau Mountainous RegionMinistry of EducationCollege of Life SciencesGuizhou UniversityGuiyang 550025China Department of Agricultural Food and Nutritional ScienceUniversity of AlbertaAlberta T6G 2P5Canada Department of Animal and Food Sciences University of KentuckyLexington 40546United States School of Liquor and Food Engineering Guizhou UniversityGuiyang 550025China

Dry-fermented sausages are a good source of bioactive peptides,whose stability against gastrointestinal(GI)digestion determines their *** study focused on evaluating the effect of peptide extracts from sausages fermented with Staphylococcus simulans QB7 during in vitro simulated GI digestion,including peptide profiles and antioxidant and anti-inflammatory *** present in sausages were degraded during digestion,with molecular weight reduced from>12 kDa to<1.5 ***,the content of amino acids increased from 381.15 to 527.07 mg/g,especially tyrosine being found only after GI *** anti-inflammatory activities were increased after GI digestion,however,the changes in antioxidant activities were the opposite.A total number of 255,252 and 386 peptide sequences were identified in undigested,peptic-digested and GI-digested samples,***,BIOPEP-UWM and admetSAR were used to further predict the functional properties and intestinal absorption of the identified peptide sequences from GI ***,18 peptides were discovered to possess either antioxidant or anti-inflammatory capacities.

关键词： Gastrointestinal digestion Sausages Bioaccessibility Anti-inflammatory activities

Almost every graph has a fixed edge

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Chinese Science Bulletin 1998年第2期43卷 99-101页

作者： fan hongbing Department of Mathematics, Shandong University, Jinan 250100, China Department of Mathematics Shandong University Jinan China

An edge e of a graph G is called a fixed edge if G-e+e′ G implies e′=e, and an isomorphic fixed edge if G-e+e′ G implies that there exists an automorphism of G-e, which maps the ends of e to the ends of e′. It is proved that almost every graph is with all its edges as fixed edges and isomorphic fixed edges, and it is conjectured that all graphs contain isomorphic fixed edges.

关键词： graph isomorphism automorphism group fixed edge.

EDGE RECONSTRUCTION OF PLANAR GRAPHS WITH MINIMUM DEGREE AT LEAST THREE-(Ⅰ)

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Systems Science and Mathematical Sciences 1993年第4期6卷 376-382页

作者： fan hongbing Department of Mathematics, Shandong University, Jinan 250100, China 山东大学山东济南

The object of this series of papers is to show that every planar graph ofminimum degree at least 3 is edge reconstructible. In this paper, we prove that such agraph with connectivity 2 is edge reconstructible.

关键词： Reconstruction isomorphism planar graph

EDGE RECONSTRUCTION OF PLANAR GRAPHS WITH MINIMUM DEGREE AT LEAST THREE-(IV)

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Systems Science and Mathematical Sciences 1994年第2期7卷 218-222页

作者： fan hongbing (Department of Mathematics, Shandong University, Ji’nan 250100, China)

ＥＤＧＥＲＥＣＯＮＳＴＲＵＣＴＩＯＮＯＦＰＬＡＮＡＲＧＲＡＰＨＳＷＩＴＨＭＩＮＩＭＵＭＤＥＧＲＥＥＡＴＬＥＡＳＴＴＨＲＥＥ－（ＩＶ）￥ＦＡＮＨｏｎｇｂｉｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＭａｔｈｅｍａｔｉｃｓ，Ｓｈａｎｄ... 详细信息

ＥＤＧＥＲＥＣＯＮＳＴＲＵＣＴＩＯＮＯＦＰＬＡＮＡＲＧＲＡＰＨＳＷＩＴＨＭＩＮＩＭＵＭＤＥＧＲＥＥＡＴＬＥＡＳＴＴＨＲＥＥ－（ＩＶ）￥ＦＡＮＨｏｎｇｂｉｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＭａｔｈｅｍａｔｉｃｓ，ＳｈａｎｄｏｎｇＵｎｉｖｅｒｓｉｔｙ，Ｊｉ＇...

关键词： Reconstruction planar graph embedding.

Key issues in rock mechanics of the Three Gorges Project in China

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Journal of Rock Mechanics and Geotechnical Engineering 2011年第4期3卷 329-342页

作者： Qixiang fan hongbing Zhu Xuchun Chen China Three Gorges Corporation Yichang 443002 China

The Three Gorges Project is one of the essential key projects for flood controlling and water resources regulation in the Yangtze River. The project includes a river-crossing dam, underground powerhouses, and navigation structures. Because of the huge size and complicated construction technologies, the project faced a series of challenging engineering issues. In terms of rock mechanics, there are many key technical issues, including the sliding resistance and stability of the dam section along the foundations of powerhouses No.l-5, the ,,;lope stability of the double-line five-stage shiplock, excavation of large-scale underground powerhouses, and curtain grouting under the dam. With decades of scientific research and 16 years of practical construction experiences and reservoir operations, these key technical issues in construction of the Three Gorges Project are successfully resolved, which will attribute to the development of hydropower technology. On the basis of the monitoring data during construction and normal operation periods of the Three Gorges Project, this paper presents a systematic analysis of these key rock mechanical issues in terms of behaviors, solutions, dynamic controlling, monitoring arrangement and integrated assessment.

关键词： Three Gorges Project rock mechanics dam sliding resistance and stability high shiplock slope undergroundpowerhouses curtain grouting

SIGNAL PROCESSING IN SATELLITE-BORNE RADAR ALTIMETER

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Journal of Electronics(China) 1996年第3期13卷 242-248页

作者： Ji hongbing fan Laiyao Wang Jianjun(Electronic Engineering Dept. Xidian University, Xi’an 710071) Electronic Engineering Dept Xidian University Xi’an

A new Suboptimal Maximum Likelihood Estimation (SMLE) algorithm based on full-deramp model and its implementation in satellite-borne radar altimeter are presented, with emphasis on the influence of both the return fluctuation and the receiver noise on height and slope estimation precision. Some conclusions are obtained and verified by computer simulation.

关键词： Satellite-borne radar altimeter Signal processing SMLE Estimation precision

飞灰-氢氧化钙/聚苯硫醚(PPS)滤料对烟气中单质汞的脱除

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环境工程学报 2015年第3期9卷 1349-1354页

作者：陈强刁永发范红兵东华大学环境科学与工程学院上海201620

在汞固定床实验台上进行了飞灰-氢氧化钙和PPS滤料负载飞灰-氢氧化钙吸附单质汞,以及不同温度、气体成分对滤料负载吸附剂脱除汞影响的实验研究。实验结果表明,质量配比为2∶1的飞灰-Ca(OH)2吸附剂对Hg0的脱除效果最好,最高可达到34.5%... 详细信息

在汞固定床实验台上进行了飞灰-氢氧化钙和PPS滤料负载飞灰-氢氧化钙吸附单质汞,以及不同温度、气体成分对滤料负载吸附剂脱除汞影响的实验研究。实验结果表明,质量配比为2∶1的飞灰-Ca(OH)2吸附剂对Hg0的脱除效果最好,最高可达到34.5%左右,比纯飞灰条件下的脱除效率提高了近10%。120℃条件下,PPS滤料负载飞灰-Ca(OH)2吸附剂对汞的脱除率最高达72%,远高于滤纸薄膜上吸附剂的脱除率。随着温度升高,PPS滤料负载吸附剂的脱除效率降低。HCl、SO2和NO对PPS负载吸附剂脱除汞表现出不同程度的促进作用,HCl具有很强的促进作用,少量HCl足以大幅度提高脱除效果,SO2有一定的促进作用,NO的促进效果并不明显。

关键词：飞灰-氢氧化钙吸附剂 PPS滤料 Hg0脱除

聚苯硫醚滤料协同飞灰-CaCO_3配方型吸附剂脱除烟气中Hg^0的实验研究

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环境工程学报 2014年第8期8卷 3355-3360页

作者：范红兵刁永发陈强东华大学环境科学与工程学院上海201620

通过固定床实验系统模拟烟气脱除Hg0的实验,研究了布袋常用的聚苯硫醚(polyphenylene sulfide,PPS)滤料协同飞灰-CaCO3配方型吸附剂对模拟烟气中Hg0的脱除效率,以及不同温度、气体成分对Hg0氧化及吸附的影响,分析了其影响机理。结果表明... 详细信息

通过固定床实验系统模拟烟气脱除Hg0的实验,研究了布袋常用的聚苯硫醚(polyphenylene sulfide,PPS)滤料协同飞灰-CaCO3配方型吸附剂对模拟烟气中Hg0的脱除效率,以及不同温度、气体成分对Hg0氧化及吸附的影响,分析了其影响机理。结果表明,在温度为120℃,N2+4%O2的条件下,质量比为3∶1的飞灰-CaCO3配方型吸附剂对Hg0的脱除效率最高,虽低于纯飞灰条件下的28%,但其吸附催化寿命较长;温度越高,Hg0的脱除效率越低,PPS滤料协同飞灰-CaCO3配方型吸附剂对Hg0的吸附主要表现为物理吸附;HCl对脱除Hg0的促进作用较为明显;SO2条件下其附加产物对Hg0的脱除表现出一定的抑制作用;NO对Hg0的脱除具有一定的促进作用,但与HCl相比,其促进效果较弱。

关键词： PPS滤料飞灰-CaCO3吸附剂 Hg0 脱除率

Minimal regular 2-graphs and applications

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Science China Mathematics 2006年第2期49卷 158-172页

作者： fan hongbing, LIU Guizhen & LIU Jiping Department of Physics and Computer Science, Wilfrid Laurier University, Waterloo, ON., N2L 3C5 Canada School of Mathematics and System Science, Shandong University, Jinan 250100, China Department of Mathematics and Computer Science, University of Lethbridge, Lethbridge, AB., T1K 3M4, Canada Department of Physics and Computer Science Wilfrid Laurier University Waterloo Canada School of Mathematics and System Science Shandong University Jinan China Department of Mathematics and Computer Science University of Lethbridge Lethbridge Canada

A 2-graph is a hypergraph with edge sizes of at most two. A regular 2-graph is said to be minimal if it does not contain a proper regular factor. Let f2(n) be the maximum value of degrees over all minimal regular 2-graphs of n vertices. In this paper, we provide a structure property of minimal regular 2-graphs, and consequently, prove that f2(n) = n+3-i/3, where 1 ≤ i ≤ 6, i ≡ n (mod 6) and n ≥ 7, which solves a conjecture posed by fan, Liu, Wu and Wong. As applications in graph theory, we are able to characterize unfactorable regular graphs and provide the best possible factor existence theorem on degree conditions. Moreover, fa(n) and the minimal 2-graphs can be used in the universal switch box designs, which originally motivated this study.

关键词： graph regular factor 2-graph switch box design.