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Is appendoscope a new option for the treatment of acute appendicitis?

World Journal of Gastroenterology 2024年第28期30卷 3386-3392页

作者： Shu-Jiong Feng Yi-Feng Zhou Jian-Feng Yang hong-zhang shen Guang-Xing Cui Xiao-Feng zhang Department of Gastroenterology Affiliated Hangzhou First People’s HospitalSchool of MedicineWestlake UniversityHangzhou 310000Zhejiang ProvinceChina Department of Gastroenterology Key Laboratory of Integrated Traditional Chinese and Western Medicine for Biliary and Pancreatic Diseases of Zhejiang ProvinceHangzhou 310000Zhejiang ProvinceChina Department of Gastroenterology Hangzhou Institute of Digestive DiseasesHangzhou 310000Zhejiang ProvinceChina

Acute appendicitis is a common surgical *** is commonly caused by obstruction of the appendiceal lumen due to fecaliths,tumors,or lymphoid *** over a century,appendectomy has been the primary treatment for acute *** Groves performed the first open appendectomy in *** 1983,Kurt Semm completed the first laparoscopic appendectomy,heralding a new era in ***,appendectomy is associated with certain complications and a rate of negative *** have suggested controversy over the impact of appendectomy on the development of inflammatory bowel disease and Parkinson’s disease,but an increasing number of studies indicate a possible positive correlation between appendectomy and colorectal cancer,gallstones,and cardiovascular *** the recognition that the appendix is not a vestigial organ and the advancement of endoscopic technology,Liu proposed the endoscopic retrograde appendicitis *** is an effective minimally invasive alternative for treating uncomplicated acute *** team has developed an appendoscope with a disposable digital imaging system operated through the biopsy channel of a colonoscope and successfully applied it in the treatment of *** article provides an overview of the progress in endoscopic treatment for acute appendicitis and offers a new perspective on the future direction of appendiceal disease treatment.

关键词： Acute appendicitis Endoscopic technology Endoscopic retrograde appendicitis therapy Appendoscope Appendiceal disease treatment

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穿透式自冲铆接接头成形工艺及力学性能

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塑性工程学报 2024年第5期31卷 48-54页

作者：秦怡歆邢保英张洪申王玉涛曾凯昆明理工大学机电工程学院云南昆明650500

为探究穿透式自冲铆接工艺,建立了穿透式自冲铆接过程的有限元仿真模型,并开展了工艺试验研究,探究了铆钉长度和底板厚度对铝合金/聚碳酸酯异质穿透式自冲铆接接头力学性能的影响,分析了PC板的预热温度对铆接成形裂纹产生的影响。结果表... 详细信息

为探究穿透式自冲铆接工艺,建立了穿透式自冲铆接过程的有限元仿真模型,并开展了工艺试验研究,探究了铆钉长度和底板厚度对铝合金/聚碳酸酯异质穿透式自冲铆接接头力学性能的影响,分析了PC板的预热温度对铆接成形裂纹产生的影响。结果表明,穿透式自冲铆接工艺过程可分为压紧、刺穿上板、刺穿下板和成形4个阶段;穿透式自冲铆接接头的失效载荷和能量吸收值均随着铆钉长度和底板厚度的增加而增加;热处理不仅可以抑制裂纹的产生,还可以提高接头的力学性能,预热处理后接头的最大失效载荷相较于常温处理的试样提升了26.21%。

关键词：穿透式自冲铆接接头成形工艺铆接工艺参数力学性能

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Aminated Copolymers as Flow Improvers for Super-viscous Crude Oils

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China Petroleum Processing & Petrochemical Technology 2007年第3期9卷 43-49页

作者： zhang hong shen Benxian Petroleum Processing Research Institute East China University of Science and Technology Shanghai 200237

The new flow improvers for super-viscous crude oils were developed via esterification of polybasic high carbon alcohol with methacrylate and copolymerizafion of monomers followed by amination of copolymers. The structure of the synthesized polymer flow improver additive was confirmed by IR spectroscopy and the crystal structure of the flow improver additives were determined by X-ray diffrac- tion analysis. The structure of wax crystals was also studied at the same time. The results showed that the wax crystal structure was closely related with the crystal structure of the flow improver, which could change the pour point depression and viscosity reduction behavior of the crude oil. When the wax crystal structure matched well with that of the additive, the wax crystals were dispersed satisfactorily, resulting in favorable effects in terms of pour point depression and viscosity reduction. The new synthe- sized aminated polymer flow improver additive was most efficient for treating super-viscous crude oils. The super-viscous crude oil had a high content of resins and asphaltenes, which might aggregate onto the surface of wax crystals to form blocks to limit the crude oil fluidity. However, amination of copolymers having similar structure with the resins and asphaltenes contained in crude oil could dissolve the huge polar groups to make the deposit formation difficult.

关键词： aminated copolymers flow improver super-viscous crude oil

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酸性环境下粘接剂对异质压印接头剥离强度的影响

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塑性工程学报 2024年第1期31卷 159-164页

作者：赵腾飞邢保英何晓聪曾凯张洪申昆明理工大学机电工程学院云南昆明650500

为探究酸性环境下粘接剂对异质压印接头剥离强度的影响,以热轧双相钢DP590和AA5052作为原材料,以0.02 mol·L^(-1)的NaHSO_(3)溶液作为腐蚀液,对异质压印接头(压印接头)和粘接-压印接头(粘-压复合接头)进行了干湿周浸交替腐蚀试验,通过... 详细信息

为探究酸性环境下粘接剂对异质压印接头剥离强度的影响,以热轧双相钢DP590和AA5052作为原材料,以0.02 mol·L^(-1)的NaHSO_(3)溶液作为腐蚀液,对异质压印接头(压印接头)和粘接-压印接头(粘-压复合接头)进行了干湿周浸交替腐蚀试验,通过静力学试验、微观失效断口以及能谱分析研究了接头在酸性环境下的静力学性能和失效机理。结果表明:粘接剂的使用显著提高了接头的最大失效载荷,粘-压复合接头的承载能力较压印接头提高了56.3%。粘接剂的使用对接头的失效形式未产生影响,在腐蚀时间为0 h时,压印接头和粘-压复合接头的失效形式均为内锁拉脱失效,但随着腐蚀的进行,失效形式逐渐转变为颈部断裂失效。粘-压复合接头上板的微观断口形貌均表现为韧窝状,下板拉伸失效部位的划痕逐渐加深。酸性腐蚀环境下压印接头搭接区域表面元素特征较粘-压复合接头变化明显,表明粘接剂的使用对压印接头起到了一定的保护作用。

关键词：压印接头粘-压复合接头酸性环境静力学试验微观分析

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MISCIBILITY,CRYSTALLIZATION AND MECHANICAL PROPERTIES OF PPC/PBS BLENDS

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Chinese Journal of Polymer Science 2007年第6期25卷 589-597页

作者： Hui-liang zhang Xiao-hong Sun Qing-yong Chen Min-qiao Ren Zhi-hao zhang hong-fang zhang Zhi-shen Mo State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Graduate School of Chinese Academy of Science Changchun 130022 China

In this paper, melt blends of poly（propylene carbonate）（PPC） with poly（butylene succinate）（PBS） were characterized by dynamic mechanical analysis （DMA）, differential scanning calorimetry （DSC）, tensile testing, wide-angle X-ray diffraction （WAXD）, polarized optical microscopy and thermogravimetric analysis （TGA）. The results indicated that the glass transition temperature of PPC in the 90/10 PPC/PBS blend was decreased by about 11 K comparing with that of pure PPC. The presence of 10% PBS was partially miscible with PPC. The 90/10 PPC/PBS blend had better impact and tensile strength than those of the other PPC/PBS blends. The glass transition temperature of PPC in the 80/20, 70/30, and 60/40 PPC/PBS blends was improved by about 4.9 K, 4.2 K, and 13 K comparing with that of pure PPC, respectively; which indicated the immiscibility between PPC and PBS. The DSC results indicated that the crystallization of PBS became more difficult when the PPC content increased. The matrix of PPC hindered the crystallization process of PBS. While the content of PBS was above 20%, significant crystallization-induced phase separation was observed by polarized optical microscopy. It was found from the WAXD analysis that the crystal structure of PBS did not change, and the degree of crystallinity increased with increasing PBS content in the PPC/PBS blends.

关键词： Poly(propylene carbonate) Poly(butylene succinate) Miscibility Crystallization Mechanical properties.

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Metal stent combined with ileus drainage tube for the treatment of delayed rectal perforation: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8406-8416页

作者： Si-Le Cheng Lu Xie Hao-Wei Wu Xiao-Feng zhang Li-Lan Lou hong-zhang shen Department of Gastroenterology The Affiliated Hangzhou First People's HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Gastroenterology Zhejiang Chinese Medical UniversityHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Acute iatrogenic colorectal perforation(AICP)is a serious adverse event,and immediate AICP usually requires early endoscopic *** surgical repair is required if the perforation is large,the endoscopic closure fails,or the patient's clinical condition *** cases of delayed AICP(>4 h),surgical repair or enterostomy is usually performed,but delayed rectal perforation is *** SUMMARY A 53-year-old male patient underwent endoscopic submucosal dissection(ESD)at a local hospital for the treatment of a laterally spreading tumor of the rectum,and the wound was closed by an endoscopist using a purse-string ***,the patient then presented with delayed rectal perforation(6 h after ESD).The surgeons at the local hospital attempted to treat the perforation and wound surface using transrectal endoscopic microsurgery(TEM);however,the perforation worsened and became enlarged,multiple injuries to the mucosa around the perforation and partial tearing of the rectal mucosa occurred,and the internal anal sphincter was *** a result,the perforation became more *** to the increased bleeding,surgical treatment with suturing could not be performed using ***,the patient was sent to our medical center for follow-up *** a multidisciplinary discussion,we believed that the patient should undergo an ***,the patient strongly refused this treatment *** the position of the rectal perforation was relatively low and the intestine had been adequately prepared,we attempted to treat the complicated delayed rectal perforation using a self-expanding covered mental stent(SECMS)in combination with a transanal ileus drainage tube(TIDT).CONCLUSION For patients with complicated delayed perforation in the lower rectum and adequate intestinal preparation,a SECMS combined with a TIDT can be used and may result in very good outcomes.

关键词： Endoscopic submucosal dissection Complicated delayed rectal perforation Delayed perforation Transanal ileus drainage tube Self-expanding covered metallic stent Case report

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Hydrodynamic Characteristics of Undular Tidal Bores in the Qiantang River Based on Field Observations

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China Ocean Engineering 2024年第3期38卷 505-518页

作者： zhang Shu-yu PAN Cun-hong zhang shen-yang LI Ruo-hua CHENG Wenlong XIE Dong-feng Zhejiang Tongji Vocational College of Science and Technology Hangzhou 311231China Zhejiang Institute of Hydraulics and Estuary Hangzhou 310020China

Understanding the undular tidal bores in the Qiantang River is essential for effective river management and *** breaking tidal bores have been studied extensively, reports on undular tidal bores in the Qiantang Riverremain limited. Furthermore, observed data on undular tidal bores fulfilling the requirements of short measurementtime intervals, and spring, medium, and neap tide coverage, and providing detailed data for the global vertical stratificationof flow velocity are quite limited. Based on field observations at Qige in the Qiantang estuary, we analyzedthe characteristics of undular tidal bores. The results showed that the flooding amplitude (a) of the first wave isalways larger than its ebbing amplitude (b). Moreover, the vertical distribution of the maximum flood velocity exhibitesthree shapes, influenced by the tidal range, while that of the maximum ebb velocity exhibites a single shape. Duringthe initial phase of the flood tide in the spring and medium tides, the upper water body experiences multiple oscillatingchanges along the flow direction, corresponding to the alternating process of the crest and trough of the tide levelupon the arrival of the tidal bore. The tidal range is a crucial parameter in tidal bore hydrodynamics. By establishingthe relationship between hydrodynamic parameters and tidal range, other hydrodynamic parameters, such as the tidalbore height, maximum flood depth–averaged velocity, maximum flood stratified velocity at the measurement points,and duration of the flood tide current, can be effectively predicted, thereby providing an important reference for rivermanagement and maintenance.

关键词： tidal bores Qiantang Estuary tidal bore height tidal bore velocity propagation speed

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Interventional endoscopic ultrasound for a symptomatic pseudocyst secondary to gastric heterotopic pancreas

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World Journal of Gastroenterology 2017年第34期23卷 6365-6370页

作者： hang-bin jin lei lu jian-feng yang qi-feng lou jing yang hong-zhang shen xiao-wei tang xiao-feng zhang Department of Gastroenterology Hangzhou First People’s HospitalNanjing Medical University

Heterotopic pancreas(HP) is a relatively uncommon entity that is defined as pancreatic tissue without a true anatomical or vascular connection to the pancreas. HP does not cause symptoms in most cases but can occasionally produce various manifestations, including nausea, vomiting, abdominal pain, and even heterotopic pancreatitis. Here, we report an unusual case in which heterotopic pancreatitis complicated by the formation of a pseudocyst that caused gastric outlet obstruction was diagnosed based on serum hyperamylasemia and findings from endoscopic ultrasonography(EUS)-guided fine needle aspiration(EUS-FNA) cytology. EUS-guided single pigtail stent insertion was successfully performed for recurrent gastric outlet obstruction. The patient has remained healthy and symptom-free during 4 years of surveillance. In the context of the relevant literature, the described case is a rare case of HP complicated by a pseudocyst treated via EUS-FNA and stent insertion.

关键词： Heterotopic pancreas Pseudocyst gastric outlet obstruction Endoscopic ultrasound-guided fine needle aspiration

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Single nanozyme-based colorimetric biosensor for dopamine with enhanced selectivity via reactivity of oxidation intermediates

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Chinese Chemical Letters 2024年第10期35卷 399-403页

作者： Caixia Zhu Qing hong Kaiyuan Wang Yanfei shen Songqin Liu Yuanjian zhang Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Devices Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical ResearchSchool of Chemistry and Chemical EngineeringMedical SchoolSoutheast UniversityNanjing 211189China

Reliable and selective sensing of dopamine(DA)is essential for early diagnosis of mental *** the various potential methods,nanozyme-based sensing systems have demonstrated promising sensitivity and ***,owing to the lack of substrate specificity,it is challenging to selectively detect DA using ***,based on the reactivity of the DA oxidation intermediates,we report a cascade colorimetric sensing system for the selective detection of DA using only a single *** was disclosed that the oxidation product of DA catalyzed by Co-N-doped carbon sheets(Co-N-C,a common oxidase-like nanozyme),dopamine quinone(DAQ),showed significant biocatalytic electron-donating activity in the reduction of O_(2)to generate O_(2)·-.Further using O_(2)·-to oxidize3,3,5,5-tetramethylbenzidine(TMB),a colorimetric sensing platform for DA was constructed with a linear detection range of 50 nmol/L to 50μmol/L and a low limit of detection of 4 nmol/*** to the reactivity of the oxidation product,without any biometric units(such as nucleic acids,enzymes,and antibodies/antigens),the reaction selectivity of DA against other interferences(e.g.,ascorbic acid,adrenaline,5-hydroxytryptamine,and glutathione)was enhanced up to *** complicated cascade systems requiring at least two nanozymes,sophisticated artificial recognition via multiple interactions was simplified by exploiting the oxidative properties of product intermediates;thus,only a single common oxidase-like nanozyme was *** work offers a new strategy to enhance the selectivity of nanozymes for bioanalytical applications.

关键词： Nanozyme Colorimetry Selectivity Dopamine Artificial recognition

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China CDC weekly 2024年第37期6卷 968-971页

作者： Zou Chen hong zhang Yifeng shen Chuchu Ye Shanghai Pudong New Area Center for Disease Control and Prevention ShanghaiChina Fudan University Pudong Institute of Preventive Medicine ShanghaiChina

What is already known about this topic?Noroviruses are highly infectious with rapid transmission capabilities,causing illness for an average duration of 12-60 *** China,individuals in educational agencies may return to class 72 hours after symptom *** is added by this report?This outbreak was precipitated by a potential source of infection in a child resuming class after a 72-hour quarantine post-symptom resolution,leading to a cluster of cases within the *** are the implications for public health practice?While extending the quarantine period for children may be considered from a safety perspective,it is a challenge for educational *** outbreak is deemed a low-probability event;however,further investigation into the detoxification period of asymptomatic patients is warranted.

关键词： return break Nor

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