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Liquid Crystal Based Label-Free Optical Sensors forBiochemical Application

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Photonic Sensors 2024年第2期14卷 57-88页

作者： Jieyuan TANG Zhibin LI Mengyuan XIE yunhan luo Jianhui yu Guojie CHEN Zhe CHEN School of Physics and Optoelectronic Engineering Foshan UniversityFoshan 528225China Guangdong-hong Kong.Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan UniversiyFoshan 528225China Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes Jinan UniversityGuangzhou 510632.China Department of Optoelectronic Engineering Jinan UniversityGuangzhou 510632China JiHua Laboratory Foshan 528200China

Biochemical sensors have important applications in biology,chemistry,and ***,many biochemical sensors are hampered by intricate techniques,cumbersome procedures,and the need for *** the past two decades,it has been discovered that liquid crystals can be used to achieve the optical amplification of biological *** modifying recognition molecules,a variety of label-free biochemical sensors can be ***,biochemical sensors based on the amplification of liquid crystals have become one of the most promising *** paper describes in detail the optical sensing principle of liquid crystals,sensing devices,and optical detection ***,the latest research findings are ***,the challenges and future research directions are discussed.

关键词： Optical sensor biochemistry liquid crystal label-free

Full-parameter omnidirectional transformation optical devices

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National Science Review 2024年第3期11卷 92-99页

作者： yuan Gao yu luo Jingjing Zhang Zhengjie Huang Bin Zheng hongsheng Chen Dexin Ye Interdisciplinary Center for Quantum Information State Key Laboratory of Extreme Photonics and InstrumentationZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang University School of Electrical and Electronic Engineering Nanyang Technological University CNRS-InternationalNTU-Thales Research Alliance Nanyang Technological University Institute of Electromagnetic Space Southeast University State Key Laboratory of Millimeter Waves Southeast University International Joint Innovation Center The Electromagnetics Academy at Zhejiang University Zhejiang University Key Laboratory of Advanced Micro/Nano Electronic Devices&Smart Systems of Zhejiang Jinhua Institute of Zhejiang UniversityZhejiang University Shaoxing Institute of Zhejiang University Zhejiang University

Transformation optics(TO) provides an unprecedented technique to control electromagnetic(EM) waves by engineering the constitutive parameters of the surrounding medium through a proper spatial transformation. In general, ideal transformation optical devices require simultaneous electric and magnetic responses along all three dimensions. To ease the practical implementation, previous studies usually made use of reduced parameters or other simplified approaches, which inevitably introduce extra reflection or unwanted phase shift. Up to today, experimental realizations of full-parameter transformation optical devices in free space are still quite limited. Here, a general design strategy is proposed to solve this *** a specific example, a full-parameter spatial-compression TO medium with constitutive parameters taking the diagonal form diag(a, a, 1/a) for the TM wave incidence was designed and realized experimentally. Such spatial-compression TO media were then applied to the implementation of an ideal omnidirectional invisibility cloak capable of concealing a large-scale object over a wide range of illumination angles. Both the simulation and experiment confirm that the cloak allows for nearly unity transmission of EM waves in the forward direction without introducing extra scattering or phase shift. This work constitutes an important stepping stone for future practical implementation of arbitrary full-parameter omnidirectional transformation optical devices.

关键词： transformation optical devices omnidirectional impedance matching full-parameter invisibility cloak

Hypoglycemic effect and the mechanism of action of a polysaccharide from sweet corncob in a high-fat diet and streptozotocin-induced diabetic mice

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Food Science and Human Wellness 2024年第3期13卷 1543-1555页

作者： Xin Wang Weiye Xiu Ye Han Zhili Wang yu luo Yongqiang Ma Heilongjiang Provincial Key Laboratory of Cereals and Comprehensive Processing of Cereal Resources College of Food EngineeringHarbin University of CommerceHarbin 150028China

Type 2 diabetes mellitus(T2DM)is a metabolic disease caused by a glycolipid metabolism disorder and isletβ-cell ***-80-I is a biologically active water-soluble polysaccharide isolated from sweet corncob,an agricultural *** hypoglycemic effects of SCP-80-I on T2DM mice and its mechanisms were investigated in this ***-80-I was found to significantly reduce blood glucose and lipid deposition levels in T2DM mice,as well as decrease serum leptin and increase adiponectin ***,real time-polymerase chain reaction(RT-PCR)and Western blotting results revealed that SCP-80-I could regulate the expression of several glycolipid metabolisms and insulin secretion genes and proteins,including 5'-AMP-activated protein kinase(AMPK),carnitine palmitoyltransferase I(CPTI),and acetyl coenzyme A carboxylase(ACC)in the liver and AMPK,sirtuin1(Sirtl),peroxisome proliferator-activated receptorycoactivator-1(PGC-1α),and uncoupling protein 2(UCP2)in the *** have a hypoglycemic effect,SCP-80-1 regulated glycolipid metabolism and islet cell function in the liver by regulating the AMPK/AC C/CPT1 signaling pathway and the AMPK/Sirt1/PGC-1αand AMPK/Sirtl/UCP2 signaling *** findings improve our understanding of polysaccharides derived from sweet corncob and the use of SCP-80-I in the production of hypoglycemic foods.

关键词： Sweet corn cob polysaccharide Type 2 diabetes Signal pathway 5’-AMP-activated protein kinase(AMPK)

Numerical modeling of all-day albedo variation for bifacial PV systems on rooftops and annual yield prediction in Beijing

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Building Simulation 2024年第6期17卷 955-964页

作者： Xiaoxiao Su Chenglong luo Xinzhu Chen Jie Ji Yanshun yu yuandan Wu Wu Zou School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing210094China Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230027China Institute of Energy Research Jiangxi Academy of SciencesNanchang330096China

Bifacial PV modules capture solar radiation from both sides,enhancing power generation by utilizing reflected ***,there are difficulties in obtaining ground albedo data due to its dynamic *** address this issue,this study established an experimental testing system on a rooftop and developed a model to analyze dynamic albedo variations,utilizing specific data from the *** results showed that the all-day dynamic variations in ground albedo ranged from 0.15 to 0.22 with an average of ***,this study evaluates the annual performance of a bifacial PV system in Beijing by considering the experimental conditions,utilizing bifacial modules with a front-side efficiency of 21.23%and a bifaciality factor of 0.8,and analyzing the dynamic all-day albedo data obtained from the numerical *** results indicate that the annual radiation on the rear side of bifacial PV modules is 278.90 kWh/m^(2),which accounts for only 15.50%of the front-side ***,when using the commonly default albedo value of 0.2,the rear-side radiation is 333.01 kWh/m^(2),resulting in an overestimation of 19.40%.Under dynamic albedo conditions,the bifacial system is predicted to generate an annual power output of 412.55 kWh/m^(2),representing a significant increase of approximately 12.37%compared to an idealized monofacial PV system with equivalent front-side *** a 25-year lifespan,the bifacial PV system is estimated to reduce carbon emissions by 8393.91 kgCO_(2)/m^(2),providing an additional reduction of 924.31 kgCO_(2)/m^(2)compared to the idealized monofacial PV *** findings offer valuable insights to promote the application of bifacial PV modules.

关键词： bifacial PV module ground albedo simulation carbon emission reduction

Roles of nanoparticles in arsenic mobility and microbial community composition in arsenic-enriched soils

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Journal of Environmental Sciences 2024年第4期138卷 301-311页

作者： Ting luo Qining Zheng Jie yu Weihao Liang Yan Sun Guixiang Quan Feng Zhou School of Environmental Science and Engineering Yancheng Institute of TechnologyYancheng 224051China Jiangsu Provincial Key Laboratory of Coastal Ecology and Pollution Control Yancheng 224051China School ofEnvironment and Civil Engineering Jiangnan UniversityWuxi 214122China

Environmental effects of nano remediation engineering of arsenic(As)pollution need to be *** this study,the roles of Fe_(2)O_(3)and TiO_(2)nanoparticles(NPs)on the microbial mediated As mobilization from As contaminated soil were *** addition of Fe_(2)O_(3)and TiO_(2)NPs restrained As(V)release,and stimulated As(Ⅲ)***(V)concentration decreased by 94% and 93% after Fe_(2)O_(3)addition,and decreased by 89% and 45% after Ti O_(2)addition compared to the Biotic and Biotic+Acetate(amended with sodium acetate)controls,*** maximum values of As(Ⅲ)were 20.5 and 27.1μg/L at 48 d after Fe_(2)O_(3)and TiO_(2)NPs addition,respectively,and were higher than that in Biotic+Acetate control(12.9μg/L).The released As co-precipitated with Fe in soils in the presence of Fe_(2)O_(3)NPs,but adsorbed on TiO_(2)NPs in the presence of TiO_(2)***,the addition of NPs amended with sodium acetate as the electron donor clearly promoted As(V)reduction induced by *** NPs addition changed the relative abundance of soil bacterial community,while Proteobacteria(42.8%-70.4%),Planctomycetes(2.6%-14.3%),and Firmicutes(3.5%-25.4%)were the dominant microorganisms in *** potential As/Fe reducing bacteria were related to Pseudomonas,Geobacter,Desulfuromonas,and *** addition of Fe_(2)O_(3)and TiO_(2)NPs induced to the decrease of arr A *** results indicated that the addition of NPs had a negative impact on soil microbial population in a long *** findings offer a relatively comprehensive assessment of Fe_(2)O_(3)and TiO_(2)NPs effects on As mobilization and soil bacterial communities.

关键词： Fe_(2)O_(3)and TiO_(2)nanoparticles Arsenic reduction Mobilization Functional gene Microbial community

Challenges and strategies of chlorine inhibition in anode systems for seawater electrolysis

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Science China Chemistry 2024年第10期67卷 3198-3208页

作者： Chuqiang Huang Zhouzhou Wang Shaojun Cheng yunpeng Liu Binglu Deng Shaoyi Xu luo yu Ying yu School of Materials Science and Hydrogen Energy Foshan University Institute of Nanoscience and Nanotechnology College of Physical Science and TechnologyCentral China Normal University Department of Physics and Texas Center for Superconductivity at the University of Houston (TcSUH) University of Houston Laboratory of Solar Fuel Faculty of Materials Science and ChemistryChina University of Geosciences

Seawater electrolysis for green hydrogen production is one of the key technologies for achieving carbon neutrality. However, in anode systems, the chloride ions（Cl-） in seawater will trigger an undesired chlorine evolution reaction（CER） that competes with an oxygen evolution reaction（OER）, resulting in inferior OER activity and selectivity. Besides, the corrosive Cl-and its derivative products will corrode anodes during seawater electrolysis, leading to poor stability. Therefore, great efforts have been devoted to developing efficient strategies for chlorine inhibition to improve the activity, selectivity, and stability of anode materials. Herein, focusing on chlorine inhibition, we present a mini review to comprehensively and concisely summarize the recent progress in anode systems for boosting seawater electrolysis. In particular, two strategies of physical and chemical regulation to inhibit Cl-are summarized in some representative cases. Finally, some challenges and future opportunities in anode systems for seawater electrolysis are prospected. This mini review aims to shed light on designing highly efficient anode materials for seawater electrolysis.

关键词： seawater electrolysis anode systems chlorine inhibition physical regulation chemical regulation

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High-frequency repetitive transcranial magnetic stimulation promotes neural stem cell proliferation after ischemic stroke

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Neural Regeneration Research 2024年第8期19卷 1772-1780页

作者： Jing luo yuan Feng Zhongqiu hong Mingyu Yin Haiqing Zheng Liying Zhang Xiquan Hu Department of Rehabilitation Medicine The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Hepatobiliary Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Prolife ration of neural stem cells is crucial for promoting neuronal regeneration and repairing cerebral infarction *** magnetic stimulation(TMS)has recently emerged as a tool for inducing endogenous neural stem cell regeneration,but its underlying mechanisms remain unclea r In this study,we found that repetitive TMS effectively promotes the proliferation of oxygen-glucose deprived neural stem ***,repetitive TMS reduced the volume of cerebral infa rction in a rat model of ischemic stro ke caused by middle cerebral artery occlusion,im p roved rat cognitive function,and promoted the proliferation of neural stem cells in the ischemic ***-sequencing found that repetitive TMS activated the Wnt signaling pathway in the ischemic penumbra of rats with cerebral ***,PCR analysis revealed that repetitive TMS promoted AKT phosphorylation,leading to an increase in mRNA levels of cell cycle-related proteins such as Cdk2 and *** effect was also associated with activation of the glycogen synthase kinase 3β/β-catenin signaling pathway,which ultimately promotes the prolife ration of neural stem ***,we validated the effect of repetitive TMS on AKT *** found that repetitive TMS promoted Ca2+influx into neural stem cells by activating the P2 calcium channel/calmodulin pathway,thereby promoting AKT phosphorylation and activating the glycogen synthase kinase 3β/β-catenin *** findings indicate that repetitive TMS can promote the proliferation of endogenous neural stem cells through a Ca2+influx-dependent phosphorylated AKT/glycogen synthase kinase 3β/β-catenin signaling *** study has produced pioneering res ults on the intrinsic mechanism of repetitive TMS to promote neural function recove ry after ischemic stro *** results provide a stro ng scientific foundation for the clinical application of repetitive ***,repetitive TMS treatment may not only be an efficient an

关键词： AKT/β-catenin signaling brain stimulation Ca2+influx cell proliferation ischemic stroke middle cerebral artery occlusion neural stem cells neurological rehabilitation repetitive transcranial magnetic stimulation

Effects of Helicobacter pylori and Moluodan on the Wnt/β-catenin signaling pathway in mice with precancerous gastric cancer lesions

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 979-990页

作者： Yi-Mei Wang Zheng-Wei luo yu-Lin Shu Xiu Zhou Lin-Qing Wang Chun-hong Liang Chao-Qun Wu Chang-Ping Li Department of Gastroenterology The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND Helicobacter pylori(***)is the primary risk factor for gastric cancer(GC),the Wnt/β-Catenin signaling pathway is closely linked to *** has a high mortality rate and treatment cost,and there are no drugs to prevent the progression of gastric precancerous lesions to ***,it is necessary to find a novel drug that is inexpensive and preventive to against *** To explore the effects of *** and Moluodan on the Wnt/β-Catenin signaling pathway and precancerous lesions of GC(PLGC).METHODS Mice were divided into the control,N-methyl-N-nitrosourea(MNU),***+MNU,and Moluodan *** first created an *** infection model in the ***+MNU and Moluodan groups.A PLGC model was created in the remaining three groups except for the control *** was fed to mice in the Moloudan group ad *** general condition of mice were observed during the whole experiment *** tissues of mice were grossly and microscopically *** quantitative real-time PCR(qRT-PCR)and Western blotting analysis,the expression of relevant genes were *** Mice in the ***+MNU group showed the worst performance in general condition,gastric tissue visual and microscopic observation,followed by the MNU group,Moluodan group and the control ***-PCR and Western blotting analysis were used to detect the expression of relevant genes,the results showed that the ***+MNU group had the highest expression,followed by the MNU group,Moluodan group and the control *** *** can activate the Wnt/β-catenin signaling pathway,thereby facilitating the development and progression of *** suppressed the activation of the Wnt/β-catenin signaling pathway,thereby decreasing the progression of PLGC.

关键词： Helicobacter pylori Gastric cancer Wnt/β-catenin signaling pathway Moluodan

A survey on model-based reinforcement learning

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Science China(Information Sciences) 2024年第2期67卷 59-84页

作者： Fan-Ming luo Tian XU Hang LAI Xiong-Hui CHEN Weinan ZHANG Yang yu National Key Laboratory for Novel Software Technology Nanjing University Polixir. ai Department of Computer Science and Engineering Shanghai Jiao Tong University

Reinforcement learning(RL) interacts with the environment to solve sequential decision-making problems via a trial-and-error approach. Errors are always undesirable in real-world applications, even though RL excels at playing complex video games that permit several trial-and-error attempts. To improve sample efficiency and thus reduce errors, model-based reinforcement learning(MBRL) is believed to be a promising direction, as it constructs environment models in which trial-and-errors can occur without incurring actual costs. In this survey, we investigate MBRL with a particular focus on the recent advancements in deep RL. There is a generalization error between the learned model of a non-tabular environment and the actual environment. Consequently, it is crucial to analyze the disparity between policy training in the environment model and that in the actual environment, guiding algorithm design for improved model learning, model utilization, and policy training. In addition, we discuss the recent developments of model-based techniques in other forms of RL, such as offline RL, goal-conditioned RL, multi-agent RL, and meta-RL. Furthermore,we discuss the applicability and benefits of MBRL for real-world tasks. Finally, this survey concludes with a discussion of the promising future development prospects for MBRL. We believe that MBRL has great unrealized potential and benefits in real-world applications, and we hope this survey will encourage additional research on MBRL.

关键词： reinforcement learning model-based reinforcement learning planning model learning model learning with reduced error model usage