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Chinese Journal of Polymer Science 2014年第2期32卷 187-196页

作者： hong-ying zhao 赵京波 Hao Li Tong zhao Key Laboratory of Carbon Fiber and Functional Polymers Ministry of Education College of Materials Science and Engineering Beijing University of Chemical Technology Laboratory of Advanced Polymer Materials Institute of Chemistry Chinese Academy Science

Two polyborosiloxanes （PBSis） with char yield up to 74.13% at 800 ℃ were synthesized by the direct polycondensation of boric acid with phenyltrimethoxysilane in diglyme. The PBSis were characterized by gel permeation chromatography, IR spectroscopy as well as ^1H-, ^29Si- and ^11B-NMR. PBSi modified phenol-formaldehyde resins （PBSi/PFs） were prepared at different PBSi/PF mass ratios and were cured at 150 ℃. The PBSi/PFs were characterized by IR spectroscopy, scanning electron microscopy, thermogravimetric analysis and tensile test. The results revealed that the cured PBSi/PFs had sea-island morphology and higher char yield than the common PF. PBSi/PF blend with PBSi/PF mass ratio of 0.4：1 had char yield up to 70.83% at 800 ℃. The PBSi/PFs had tensile strength similar to PF. The ceramization of PBSi/PFs was also studied. The silicon boron oxycarbide （SiBOC） ceramics formed were characterized by IR spectroscopy and elemental analysis. This method provided a valuable way to prepare easily shapeable polymer blends as ceramic precursors.

关键词： Polyborosiloxane Phenolic resin Preparation Ceramic precursors SiBOC ceramics.

A SEMI-OPEN-LOOP CODING MODE SELECTION ALGORITHM BASED ON EFM AND SELECTED AMR-WB+ FEATURES

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Journal of Electronics(China) 2009年第2期26卷 274-278页

作者： hong ying zhao Shenghui Kuang Jingming School of Information Science and Technology Beijing Institute of Technology Beijing 100081 China

To solve the problems of the AMR-WB+(Extended Adaptive Multi-Rate-WideBand) semi-open-loop coding mode selection algorithm,features for ACELP(Algebraic Code Excited Linear Prediction) and TCX(Transform Coded eXcitation) classification are investigated.11 classifying features in the AMR-WB+ codec are selected and 2 novel classifying features,i.e.,EFM(Energy Flatness Measurement) and stdEFM(standard deviation of EFM),are ***,a novel semi-open-loop mode selection algorithm based on EFM and selected AMR-WB+ features is *** results of classifying test and listening test show that the performance of the novel algorithm is much better than that of the AMR-WB+ semi-open-loop coding mode selection algorithm.

关键词： Speech/Audio Semi-open-loop coding mode selection Features selection Energy Flat-ness Measurement(EFM)

Efficacy and safety of stellate ganglion block in chronic ulcerative colitis

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World Journal of Gastroenterology 2017年第3期23卷 533-539页

作者： hong-ying zhao Guo-Tao Yang Ning-Ning Sun Yu Kong Yun-Feng Liu Department of Elderly Internal Medicine Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of Third Neurology Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of First Digestion Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of Second Digestion Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina

AIM To investigate the efficacy and safety of stellate ganglion block for the treatment of patients with chronic ulcerative *** A total of 120 randomly selected patients with chronic ulcerative colitis treated in Cangzhou Central Hospital from January 2014 to January 2016 were included in this study. These patients were divided into two groups: control group(n = 30), patients received oral sulfasalazine treatment; experimental group(n = 90), patients received stellate ganglion block treatment. Clinical symptoms and disease activity in these two groups were compared before and after treatment using endoscopy. Blood was collected from patients on day 0, 10, 20 and 30 after treatment. Enzyme-linked immunosorbent assay was performed to determine interleukin-8(IL-8) level. The changes in IL-8 level post-treatment in the two groups were compared using repeated measures analysis of *** After treatment, clinical symptoms and disease activity were shown to be alleviated by endoscopy in both the control and experimental groups. However, patients in the control group did not have obvious abdominal pain relief. In addition, the degree of pain relief in the experimental group was statistically better than that in the control group(P < 0.05). Ten days after treatment, IL-8 level was found to be significantly lower in the experimental group than in the control group, and the difference was statistically significant(P < 0.05). In addition, adverse events were significantly higher in the control group than in the experimental group, and the difference was statistically significant(χ~2 = 33.215, P = 0.000).CONCLUSION The application of stellate ganglion block effectively improves treatment efficacy in chronic ulcerative colitis, relieves clinical symptoms in patients, and reduces the level of inflammatory factors. Furthermore, this approach also had a positive impact on the disease to a certain extent.

关键词： Stellate ganglion block Chronic ulcerative colitis

Correlation between serum vitamin B12 level and peripheral neuropathy in atrophic gastritis

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World Journal of Gastroenterology 2018年第12期24卷 1343-1352页

作者： Guo-Tao Yang hong-ying zhao Yu Kong Ning-Ning Sun Ai-Qin Dong Department of Third Neurology Cangzhou Central Hospital Cangzhou Clinical Medical School of Hebei Medical University Department of Elderly Internal Medicine Cangzhou Central Hospital Cangzhou Clinical Medical School of Hebei Medical University Department of Second Digestion Cangzhou Central Hospital Cangzhou Clinical Medical School of Hebei Medical University Department of First Digestion Cangzhou Central Hospital Cangzhou Clinical Medical School of Hebei Medical University

AIM To explore the correlation between serum vitamin B12 level and peripheral neuropathy in patients with chronic atrophic gastritis(CAG). METHODS A total of 593 patients diagnosed with chronic gastritis by gastroscopy and pathological examination fromSeptember 2013 to September 2016 were selected for this study. The age of these patients ranged within 18-to 75-years-old. Blood pressure, height and weight were measured in each patient, and the body mass index value was calculated. Furthermore, gastric acid, serum gastrin, serum vitamin and serum creatinine tests were performed, and peripheral nerve conduction velocity and Helicobacter pylori(H. pylori) were detected. In addition, the type of gastritis was determined by gastroscopy. The above factors were used as independent variables to analyze chronic gastritis with peripheral neuropathy and vitamin B12 deficiency risk factors, and to analyze the relationship between vitamin B12 levels and peripheral nerve conduction velocity. In addition, in the treatment of CAG on the basis of vitamin B12, patients with peripheral neuropathy were observed. RESULTS Age, H. pylori infection, CAG, vitamin B9 and vitamin B12 were risk factors for the occurrence of peripheral nerve ***,CAG and H. pylori infection were risk factors for chronic gastritis associated with vitamin B12 deficiency. Serum vitamin B12 level was positively correlated with sensory nerve conduction velocity in the tibial nerve(R = 0.463). After vitamin B12 supplementation, patients with peripheral neuropathy improved. CONCLUSION Serum vitamin B12 levels in patients with chronic gastritis significantly decreased, and the occurrence of peripheral neuropathy had a certain correlation. CAG and H. pylori infection are risk factors for vitamin B12 deficiency and peripheral neuropathy. When treating CAG, vitamin B12 supplementation can significantly reduce peripheral nervous system lesions. Therefore, the occurrence of peripheral neuropathy associat

关键词： Chronic gastritis Chronic atrophic gastritis Vitamin B12 Peripheral neuropathy

Study of the effects of nesfatin-1 on gastric function in obese rats

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World Journal of Gastroenterology 2017年第16期23卷 2940-2947页

作者： Guo-Tao Yang hong-ying zhao Yu Kong Ning-Ning Sun Ai-Qin Dong Department of Third Neurology Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of Elderly Internal Medicine Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of Second Digestion Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina Department of First Digestion Cangzhou Central HospitalCangzhou Clinical Medical School of Hebei Medical UniversityCangzhou 061001Hebei ProvinceChina

AIM To investigate the effects of nesfatin-1 on gastric function in obese rats. METHODS The obese rat model was induced by a high-fat diet. The gastric emptying rate and gastric acid secretory capacity of the rats were determined after treatment with different drug concentrations of nesfatin-1 and administration routes. Based on this, the expression of H+/K+-ATPase was measured using RT-PCR and western blot to preliminarily explore the mechanism of gastric acid secretion changes. RESULTS Body weight, body length, and Lee's index of the rats significantly increased in the high-fat dietinduced obese rat model. Two hours after lateral intracerebroventricular injection of nesfatin-1, the gastric emptying rate and gastric acid secretory capacity of rats decreased. Four hours after injection, both were restored to normal levels. In addition, the expression of H+/K+-ATPase decreased and moved in line with changes in gastric acid secretory capacity. Thisin vivo experiment revealed that intracerebroventricular injection of nesfatin-1, rather than intravenous injection, could suppress gastric function in obese rats. Moreover, its effect on the gastric emptying and gastric acid secretory capacity of rats is dose-dependent within a certain period of *** Through this research, we provide a theoretical basis for further studies on nesfatin-1, a potential antiobesity drug.

关键词： Obesity Nesfatin-1 H^+/K^+-ATPase

Flexible molecules dedicate to release strain of inverted inorganic perovskite solar cell

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Journal of Energy Chemistry 2025年第1期100卷 87-93页

作者： hongrui Sun Sanlong Wang Pengyang Wang Yali Liu Shanshan Qi Biao Shi ying zhao Xiaodan Zhang Institute of Photoelectronic Thin Film Devices and Technology Renewable Energy Conversion and Storage Center State Key Laboratory of Photovoltaic Materials and CellsNankai University Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Haihe Laboratory of Sustainable Chemical Transformations Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells （IPSCs）,which reduces the defect formation ***,a flexible molecule 5-maleimidovaleric acid （5-MVA） was introduced as a strain buffer to release the residual strain of *** anhydride and carboxyl groups in 5-MVA interact strongly with the uncoordinated Pb2+through Lewis acid-base reaction,thus tightly“pull”the perovskite *** in-between soft carbon chain increased the structural flexibility of CsPbI2.85Br0.15perovskite materials,which effectively relieved the intrinsic internal strain of CsPbI2.85Br0.15,resisted the corrosion of external strain,and also reduced the formation of defects such as VIand *** addition,the introduction of 5-MVA improved crystal quality,passivated residual defects,and narrowed energy level ***,power conversion efficiency （PCE） of NiOxbased inverted IPSCs increased from 19.25% to 20.82% with the open-circuit voltage enhanced from 1.164 V to 1.230 *** release of strain also improved the stability of CsPbI2.85Br0.15perovskite films and devices.

关键词： Inverted inorganic perovskite solar cells Flexible molecules Strain release Crystallization Energy barrier High PCE

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网上社科信息资源建设与开发标准化问题研究

图书情报工作 2003年第6期47卷 20-23页

作者：洪颖赵妍姝天津音乐学院图书馆天津300171 天津南开大学图书馆学系天津300071

论述网上社科信息资源的特点和存在问题,从宏观和微观两个角度对网上社科信息资源标准化问题进行深入的分析。

关键词：网络信息资源社科信息资源资源建设开发利用标准化资源共享导航服务

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang zhao Mingkai Zhang Qimeng Li Xuemin Wang Jie Lu ying Han Yanning Cai Department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

A Novel Digital Audio Watermarking Scheme in the Wavelet Domain

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A Novel Digital Audio Watermarking Scheme in the Wavelet Dom...

中药制剂中绿原酸的电化学敏感测定及其与DNA的相互作用

The 1st Chinese Conference on Trusted Computing and Information Security

作者： Xiang-yang, YANG hong-ying, zhao hong School of Computer and Information Technique, Liaoning Normal University, Dalian 116029, Liaoning,China State Key Laboratory of Information Security, Institute of Software of Chinese Academy of Sciences, Beijing 100039, China

＜正＞ We present a novel quantization-based digital audio watermarking scheme in wavelet domain. By quantizing a host audio’ s wavelet coefficients （Integer Lifting Wavelet Transform ） and utilizing the characteristics of human auditory system （HAS）, the gray image is embedded using our watermarking method. Experimental results show that the proposed watermarking scheme is inaudible and robust against various signal processing such as noising adding, lossy compression, low pass filtering, re-sampling, and re-quantifying.

关键词： digital audio watermarking lifting wavelet transform human auditory system chaotic sequence quantization

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分析测试学报 2017年第3期36卷 398-402,408页

作者：李红英赵炜王学亮汪涛王朝霞中国矿业大学化工学院江苏徐州221116 菏泽学院化学化工系山东菏泽274015

制备了铂纳米粒子和聚3,4-乙烯二氧噻吩(PEDOT)修饰玻碳电极,并将此电极用于绿原酸的电化学研究。实验结果表明,相比裸电极,绿原酸在此修饰电极上的氧化还原峰电流均有所增加,尤以氧化峰电流增加显著。最佳实验条件下,绿原酸的氧化峰电... 详细信息

制备了铂纳米粒子和聚3,4-乙烯二氧噻吩(PEDOT)修饰玻碳电极,并将此电极用于绿原酸的电化学研究。实验结果表明,相比裸电极,绿原酸在此修饰电极上的氧化还原峰电流均有所增加,尤以氧化峰电流增加显著。最佳实验条件下,绿原酸的氧化峰电流与其浓度在0.2~100μmol/L范围内呈良好的线性关系,检出限为0.05μmol/L。相比较已报道的其它方法,此方法线性范围较宽,检出限较低。将此电极用于中药制剂双黄连注射液中绿原酸含量的测定,测得加标回收率为97.7%~102.1%。对绿原酸与DNA的相互作用进行研究,得到它们的结合数为3,结合常数为1.62×103L/mol。相关参数可为绿原酸的药理研究以及相似药物的筛选提供参考与理论指导。

关键词：绿原酸修饰电极 PEDOT 铂纳米粒子 DNA