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Do stress fractures induce hypertrophy of the grafted fibula？ A report of three cases received free vascularized fibular graft treatment for tibial defects

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Chinese Journal of Traumatology 2016年第3期19卷 179-181页

作者： Yong Qi hong-Tao Sun Yue-Guang Fan Fei-Meng Li zhou-Sheng Lin Department of Orthopaedics Guangdong Second People's Hospital Guangzhou 510317 China Guangzhou University of Traditional Chinese Medicine Guangzhou 510405 China Department of Orthopaedics The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Guangzhou 510405 China

The presence of large segmental defects of the diaphyseal bone is challenging for orthopedic surgeons. Free vascularized fibular grafting （FVFG） is considered to be a reliable reconstructive procedure. Stress fractures are a common complication following this surgery, and hypertrophy is the main physiological change of the grafted fibula. The exact mechanism of hypertrophy is not completely known. To the best of our knowledge, no studies have examined the possible relationship between stress fractures and hypertrophy. We herein report three cases of patients underwent FVFG. Two of them developed stress fractures and significant hypertrophy, while the remaining patient developed neither stress fractures nor significant hypertrophy. This phenomenon indicates that a relationship may exist between stress frac~ tures and hypertrophy of the grafted fibula, specifically, that the presence of a stress fracture may initiate the process of hypertrophy,

关键词： Free vascularized fibular graftsBone defectsFractures stressHypertrophy

From gut changes to type 2 diabetes remission after gastric bypass surgeries

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Frontiers of Medicine 2013年第2期7卷 191-200页

作者： Bing Li Xinrong zhou Jiarui Wu Huarong zhou Key Laboratory of Systems Biology SIBS-Novo Nordisk Translational Research Centre for PreDiabetesShanghai Institutes for Biological SciencesCASShanghai 200233China Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Increasing evidence suggests that the gut may influence the host’s metabolism and ultimately change the outcomes of type 2 diabetes mellitus(T2DM).We review the evidence on the relationship between the gut and T2DM remission after gastric bypass surgery,and discuss the potential mechanisms underlying the above relationship:gut anatomical rearrangement,microbial composition changes,altered gut cells,and gut hormone ***,the exact changes and their relative importance in the metabolic improvements after gastric bypass surgery remain to be further *** the precise metabolic mechanisms of T2DM resolution after bypass surgery will help to reveal the molecular mechanisms of pathogenesis,and facilitate the development of novel diagnoses and preventative interventions for this common disease.

关键词： gastric bypass T2DM gut

Modular chaotification model with FPGA implementation

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Science China(Technological Sciences) 2021年第7期64卷 1472-1484页

作者： HUA Zhong Yun zhou BingHang ZHANG YinXing zhou YiCong School of Computer Science and Technology Harbin Institute of TechnologyShenzhenShenzhen518055China College of Electrical and Information Engineering Hunan UniversityChangsha410082China Department of Computer and Information Science University of MacaoMacao999078China

Chaotic systems are an effective tool for various applications, including information security and internet of things. Many chaotic systems may have the weaknesses of incomplete output distributions, discontinuous chaotic regions, and simple chaotic *** may result in many negative influences in practical applications utilizing chaos. To deal with these issues, this study introduces a modular chaotification model(MCM) to increase the dynamic properties of current one-dimensional(1 D) chaotic maps. To exhibit the effect of the MCM, three 1 D chaotic maps are improved using the MCM as examples. Studies of the resulting properties show the robust and complex dynamics of these improved chaotic maps. Moreover, we implement these improved chaotic maps of MCM in a field-programmable gate array hardware platform and apply them to the application of PRNG. Performance analyses verify that these chaotic maps improved by the MCM have more complicated chaotic behaviors and wider chaotic ranges than the existing and several new chaotic maps.

关键词： nonlinear system chaotic system field-programmable gate array(FPGA) pseudorandom number generator(PRNG) hardware implementation

Proteotyping:A New Approach Studying Influenza Virus Evolution at the Protein Level

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中国病毒学 2007年第5期22卷 405-411页

作者： Wei-feng SHI Zhong ZHANG Lei PENG yan-zhou ZHANG Bin LIU Chao-dong ZHU Institute of Life Sciences Taishan Medical College Shandong Tai＇an 271000 China Department of Basic Medicine Taishan Medical College Shandong Tai＇an 271000 China College of lnformation and Engineering Taishan Medical College Shandong Tai ＇an 271000 China Institute of Zoology Chinese Academy of Sciences Beijing 100101 China Department of Biological Sciences Taishan Medical College Shandong Tai＇an 271000 China

Phylogenetic methods have been widely used to detect the evolution of influenza ***,previous phylogenetic studies of influenza viruses do not make full use of the genetic information at the protein level and therefore cannot distinguish the subtle differences among viral *** is a new approach to study influenza virus *** aimed at mining the potential genetic information of the viral gene at the protein level by visualizing unique amino acid signatures(proteotypes).Neuraminidase gene fragments of some H5N1 avian influenza viruses were used as an example to illustrate how the proteotyping method *** analysis confirmed that the NA gene tree was mainly divided into three *** NA proteotype analysis further suggested there might be multiple proteotypes within these three lineages and even within single *** the same time,some proteotypes might even involve more than one *** particular,it also discovered some amino acids of viruses of some genotypes might *** these results proved this approach could provide additional information in contrast to results from standard phylogenetic tree analysis.

关键词：鸟类流行感冒病毒蛋白质基因型 H5N1 神经氨酸酶蛋白分型技术

Fabrication of inorganic-organic hybrid based on polyoxometalate SiW_(10)Fe_2 and folate as peroxidases for colorimetric immunoassay of cancer cells

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Chinese Chemical Letters 2013年第1期24卷 76-78页

作者： Zhong Sun Hai-zhou Bie Mei-Jie Wei Jing-Jing Wang Xu-Guang Mi Xiao-hong Wang Yin Wu Key Laboratory of Polyoxometalate Science of Ministry of EducationFaculty of ChemistryNortheast Normal University Changchun Central Hospital National Engineering Laboratory for Druggable Gene and Protein Screening Northeast Normal University Changchun 130024 China National Engineering Laboratory for Druggable Gene and Protein Screening Northeast Normal University

Fabrication of folate and iron-substituted polyoxometalate [（FeOH2）2SiWlo036] to form nanoparticles （FA-SiWFe2） has been achieved. This inorganic-organic hybrid possesses intrinsic peroxidase-like activity, which ... 详细信息

关键词： PolyoxometalatesPeroxidase activityColorimetric multiplexed immunoassayCancer cells

Optical super-resolution microscopy and its applications in nano-catalysis

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Nano Research 2015年第2期8卷 441-455页

作者： Wenhui Wang Junnan Gu Ting He yangbin Shen Shaobo Xi Lei Tian Feifei Li Haoyuan Li Liuming yan Xiaochun zhou Department of Chemistry College of Sciences Shanghai University 99 Shangda Road Shanghai 200444 China Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou 215123 China

The resolution of conventional optical microscopy is only -200 nm, which is becoming less and less sufficient for a variety of applications. In order to surpass the diffraction limited resolution, super-resolution microscopy （SRM） has been developed to achieve a high resolution of one to tens of nanometers. The techniques involved in SRM can be assigned into two broad categories, namely ＂true＂ super-resolution techniques and ＂functional＂ super-resolution techniques. In ＂functional＂ super-resolution techniques, stochastic super-resolution microscopy （SSRM） is widely used due to its low expense, simple operation, and high resolution. The principle process in SSRM is to accumulate the coordinates of many diffraction-limited emitters （e.g., single fluorescent molecules） on the object by localizing the centroids of the point spread functions （PSF）, and then reconstruct the image of the object using these coordinates. When the diffraction-limited emitters take part in a catalytic reaction, the activity distribution and kinetic information about the catalysis by nanoparticles can be obtained by SSRM. SSRM has been applied and exhibited outstanding advantages in several fields of catalysis, such as metal nanoparticle catalysis, molecular sieve catalysis, and photocatalysis. Since SSRM is able to resolve the catalytic activity within one nanoparticle, it promises to accelerate the development and discovery of new and better catalysts. This review will present a brief introduction to SRM, and a detailed description of SSRM and its applications in nano-catalysis.

关键词： super-resolution imaging single molecule catalysis microscopy nanoparticle

Anatomical retroperitoneoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors： initial operative experience

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Asian Journal of Andrology 2014年第1期16卷 136-139页

作者： Kai Yao Zai-Shang Li Fang-Jian zhou Zi-Ke Qin Zhuo-Wei Liu Yong-hong Li Hui Han Department of Urology Cancer Center Sun Yat-Sen University State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou China.

To introduce the technique of anatomical retroperitoneoscopic retroperitoneal lymph node dissection （ARRPLND） was performed in 12 consecutive patients with a clinical stage I nonseminomatous germ-cell tumor （NSGCT） between February 2008 and October 2010. All procedures were performed using a modified template nerve-sparing approach. The retroperitoneal space was adequately expanded using double gasbags. After the retroperitoneal fat was cleared, two relatively bloodless planes were entered consecutively to expose the lymph node and permit dissection. Dissection proceeded first in the plane between the anterior renal fascia and posterior peritoneum, and secondly in the avascular plane between the posterior renal fascia and transversalis fascia. The proximal spermatic vein was clipped at the initial stage. En bloc resection of the lymph tissue and fat between the anterior renal fascia and posterior renal fascia were performed. Three patients （25%） had pathologic stage IIA disease and received adjuvant chemotherapy. No recurrence was observed during follow-up ranging from 26 to 58months. The median operative time was 205min （range： 165-430min） and median estimated blood loss was 320ml （range： 100-1200ml）. There were two intraoperative complications （Clavien grade II） and one open conversion due to perforation of the peritoneum. Postoperative complications （Clavien I） developed in three patients. Normal antegrade ejaculation recovered by 1 month following the operation. Our preliminary results indicate that ARRPLND is technically feasible and associated with satisfactory clinical outcomes for clinical stage I NSGCT. Further studies are necessary to evaluate this technique.

关键词： nonseminomatous retroperitoneoscopic retroperitoneal lymph node testicular cancer

Quasi-One-Dimensional Free-Electron-Like States Selected by Intermolecular Hydrogen Bonds at the Glycine/Cu(100) Interface

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Chinese Physics Letters 2020年第11期37卷 75-80页

作者： Linwei zhou Chen-Guang Wang Zhixin Hu Xianghua Kong Zhong-Yi Lu hong Guo Wei Ji Department of Physics and Beijing Key Laboratory of Optoelectronic Functional Materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China Center for Joint Quantum Studies and Department of Physics Institute of ScienceTianjin UniversityTianjin 300350China Centre for the Physics of Materials and Department of Physics McGill University3600 University StreetMontrealQCH3A 2T8Canada

We carry out ab initio density functional theory calculations to study manipulation of electronic structures of selfassembled molecular nanostructures on metal surfaces by investigating the geometric and electronic properties of glycine molecules on Cu(100).It is shown that a glycine monolayer on Cu(100)forms a two-dimensional hydrogen-bonding network between the carboxyl and amino groups of glycine using a first principles atomistic calculation on the basis of a recently found *** network includes at least two hydrogen-bonding chains oriented roughly perpendicular to each *** molecule–metal electronic hybridization,these two chains selectively hybridized with the two isotropic degenerate Cu(100)surface states,leading to two anisotropic quasi-one-dimensional surface *** occupying these two states can near-freely move from a molecule to its adjacent molecules directly through the intermolecular hydrogen bonds,rather than mediated by the *** results in the experimentally observed anisotropic free-electron-like *** results suggest that hydrogen-bonding chains are likely candidates for charge conductors.

关键词： structure. chains bonding

MINING PREHOSPITAL SCORE

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中华创伤杂志 1996年第2期 82-84页

作者： zhou Zhi dao, ZHANG hong mei Beijing Mining General Hospital. Beijing 102300

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