检索结果-南通市图书馆

A novel fluorescent epoxy resin for organophosphate pesticide detection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2015年第1期26卷 39-42页

作者： hong-xing zhang Ren-Bo Wei Chuan-Zhi Chen Xin-Lin Tuo Xiao-Gong Wang Department of Chemical Engineering Laboratory of Advanced Materials(MOE)Tsinghua University Department of Chemical Defense Institute of Chemical Defense

In this work,a novel bisbenzimidazolylpyridine-functionalized fluorescent epoxy resin was synthesized for organophosphate pesticide detection.The epoxy resin was characterized by Fourier-transform infrared spectroscopy（FT-IR）,proton nuclear magnetic resonance spectroscopy（~1H NMR）,gel permeation chromatography（CPC）,differential scanning calorimetry（DSC） and fluorescence spectroscopy.After loading with Eu（Ⅲ） ions,the epoxy resin showed a strong fluorescence emission.The fluorescence emission was observed to be instantaneously quenched when exposed to trace amount of diethyl chlorophosphate in solution.The Stern-Volmer quenching constants Ksv for quenching at617 nm was determined to be 0.377 × 10^3 L/mol.This sensitive emission-quenching function and easy processing nature of the polymeric support enable the resin to be a promising chemosensor candidate for the detection of organophosphates.

关键词： MeBIP Epoxy resin Europium complex Fluorescence quenching Organophosphates

Annexin A1 in the nervous and ocular systems

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 591-597页

作者： Aijia Wang hong zhang xing Li Yin Zhao Department of Ophthalmology 2Department of AnesthesiologyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

The therapeutic potential of Annexin A1,an important member of the Annexin superfamily,has become evident in results of experiments with multiple human systems and animal models.The anti-inflammatory and pro-resolving effects of Annexin A1 are characteristic of pathologies involving the nervous system.In this review,we initially describe the expression sites of Annexin A1,then outline the mechanisms by which Annexin A1 maintains the neurological homeostasis through either formyl peptide receptor 2 or other molecular approaches;and,finally,we discuss the neuroregenerative potential qualities of Annexin A1.The eye and the nervous system are anatomically and functionally connected,but the association between visual system pathogenesis,especially in the retina,and Annexin A1 alterations has not been well summarized.Therefore,we explain the beneficial effects of Annexin A1 for ocular diseases,especially for retinal diseases and glaucoma on the basis of published findings,and we explore present and future delivery strategies for Annexin A1 to the retina.

关键词： Annexin A1(ANXA1) glaucoma nervous system neuroprotection neuroregeneration ocular disease retina

Poly(thioether)-b-polysiloxane-b-poly(thioether)triblock copolymer towards homogeneous dielectric elastomer with high dielectric performance

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2022年第8期33卷 4021-4025页

作者： Zhanbin Feng Jiafang Guo Suting Liu Guofei Feng xing-hong zhang MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China Center of Chemistry for Frontier Technologies Zhejiang UniversityHangzhou 310027China Department of Chemical Engineering Weifang Vocational CollegeWeifang 262737China

Dielectric elastomers(DEs)have drawn much attention owing to their application prospects in artificial muscles and soft robotics,it is still a big challenge to prepare DEs with high electromechanical performances.This work reports a highly stretchable poly(thioether)-b-polysiloxane-b-poly(thioether)triblock copolymer based homogenous DEs with high electromechanical properties.The triblock copolymer(PSiPGE)was synthesized through the ring-opening polymerization(ROP)of phenyl glycidyl ether(PGE)and carbonyl sulfide(COS)catalyzed by silicon alkoxides.The dipoles(benzene rings)on the side groups of PSiPGE improved the dipole polarizations and the phase separation structure of this triblock copolymer enhanced the interfacial polarizations between poly(thioether)and polysiloxane,and thus improving the dielectric constant(ε',up to 5.8).In addition,the PSiPGE exhibited low elastic modulus(Y,0.04 MPa),and thus possessed high electromechanical sensitivity(β,~145 MPa^(-1)) which is much higher than that of most homogenous DEs.This work provides a new strategy to construct homogenous DEs with excellent electromechanical performances,leading to a greater application aspect in the actuated devices.

关键词： Poly(thioether)-b-polysiloxane-bpoly(thioether)triblock copolymer Homogenous Dielectric elastomer Phase separation Electromechanical performance

Synergistic regulation of temperature resistance and thermal insulation performance of zirconia-based ceramic fibers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2023年第12期42卷 4189-4200页

作者： Yong-Shuai Xie Ying Peng Zhe-Zhe Deng Ze Zhu Yuan Cheng De-Hua Ma Lu-Yi Zhu xing-hong zhang State Key Laboratory of Crystal Materials School of Crystal MaterialsShandong UniversityJinan 250100China National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Harbin Institute of TechnologyHarbin 150001China

ZrO_(2) fiber is a promising high-temperature resistant and heat-insulating fiber material.However,the decrease in mechanical properties caused by grain growth at high temperatures seriously affects its application.How to achieve the synergy of its temperature resistance and the thermal insulation performance is still the focus of the current industry.In this work,we started with doping inequivalent elements and studied the phase composition,temperature resistance,and thermal insulation properties of Y_(2)O_(3)-ZrO_(2) ceramic fibers by adjusting the Y/Zr molar ratio.The results showed that Y_(2)O_(3) could enter the crystal lattice of ZrO_(2) and form a solid solution.With the increase in Y_(2)O_(3) content,the structure of fibers changed from a tetragonal phase to a cubic phase,and the configurational entropy of the system increased.The larger configuration entropy in the sample could produce a robust steric hindrance effect,inhibiting grain growth.After heat treatment at 1300℃,the grain size of Y_(2)Zr_(2)O_(7)(Y5Z5)fibers was only 61.8%that of Y_(0.1)Zr_(0.9)O_(1.95)(Y1Z9)fibers.The smaller grain size made the Y5Z5 fibers still have excellent flexibility and deformation recovery performance after heat treatment at 1300℃and could still return to the original state after 85%compression or folded in half.In addition,due to the larger configurational entropy,the mean free path of phonon scattering was shortened,thereby improving the thermal insulation performance of the fiber.In short,this work achieves the synergistic effect of temperature resistance and thermal insulation properties of zirconia-based fiber materials only through simple inequivalent element doping.

关键词： Ceramics fiber ZrO_(2) Y_(2)O_(3) Thermal insulation Temperature resistance

Recent Progress on COS-derived Polymers

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2019年第10期37卷 951-958,I0002页

作者： Cheng-Jian zhang xing-hong zhang Key Laboratory of Macromolecular Synthesis and Functionalization (Ministry of Education) Department of Polymer Science & Engineering Zhejiang University

The synthesis of sulfur-containing polymer, a very promising functional material, has made a great progress in the past several years. This review is focused on the very recent advances in poly(monothiocarbonate)s derived from carbonyl sulfide(COS) and epoxides including biomass-derived epoxides. Of significance, metal-free catalyst systems, including triethyl borane/Lewis base pair and thiourea/Lewis base pair are developed for the alternating copolymerization of COS with epoxides. Thereof, the thiourea/Lewis base pair is highly active to the copolymerization of COS with epoxide in a living manner. Moreover, a series of crystalline poly(monothiocarbonate)s are presented, including the copolymers derived from COS with oxetane, ethylene oxide, enantiopure epichlorohydrin, and achiral mesoepoxides via enantioselective copolymerization. Based on these COS/epoxide copolymerization process, a variety of COS-based block copolymers with well-defined structure are presented.

关键词： Carbonyl sulfide Epoxide Copolymerization Poly(monothiocarbonate)

Unified deep learning model for predicting fundus fluorescein angiography image from fundus structure image

在线全文

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2024年第3期17卷 105-113页

作者： Yiwei Chen Yi He hong Ye Lina xing Xin zhang Guohua Shi Jiangsu Key Laboratory of Medical Optics Suzhou Institute of Biomedical Engineering and TechnologyChinese Academy of SciencesSuzhou 215163P.R.China School of Biomedical Engineering(Suzhou) Division of Life Sciences and MedicineUniversity of Science and Technology of China Hefei 230026P.R.China Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghai 200031P.R.China

The prediction of fundus fluorescein angiography(FFA)images from fundus structural images is a cutting-edge research topic in ophthalmological image processing.Prediction comprises estimating FFA from fundus camera imaging,single-phase FFA from scanning laser ophthalmoscopy(SLO),and three-phase FFA also from SLO.Although many deep learning models are available,a single model can only perform one or two of these prediction tasks.To accomplish three prediction tasks using a unified method,we propose a unified deep learning model for predicting FFA images from fundus structure images using a supervised generative adversarial network.The three prediction tasks are processed as follows:data preparation,network training under FFA supervision,and FFA image prediction from fundus structure images on a test set.By comparing the FFA images predicted by our model,pix2pix,and CycleGAN,we demonstrate the remarkable progress achieved by our proposal.The high performance of our model is validated in terms of the peak signal-to-noise ratio,structural similarity index,and mean squared error.

关键词： Fundus fluorescein angiography image fundus structure image image translation unified deep learning model generative adversarial networks

Dual cooperative organocatalysts for one-pot synthesis of polyester-polythiocarbonate block copolymers from multiple monomers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2020年第12期63卷 1807-1814页

作者： Cheng-Jian zhang Xun zhang xing-hong zhang Key Laboratory of Macromolecular Synthesis and Functionalization Ministry of EducationDepartment of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China

The sequential arrangement of multiple monomer units in a polymer chain remains a major challenge in synthetic chemistry.Here we describe a versatile route to the novel polyester-polythiocarbonate block copolymer from commercially available lactones, epoxides, and carbonyl sulfide(COS). A bicomponent organocatalyst combining triazabicyclodecene(TBD) with triethyl borane(TEB) generates two types of tunable active sites, i.e., TBD-capped alcohol via hydrogen bond and TEB-capped alcohol via O→B coordination bond, which can successively catalyze ring-opening polymerization of lactones and ring-opening copolymerization of COS and epoxides from mixed monomers in one pot. Because of the reversible activated propagating anions and fast activity exchange between the active and dormant species, all of the polymer chains are enchained with both polyester and polythiocarbonate blocks. Kinetic determination quantitatively confirms the proposed mechanism. This method enables diverse lactones and epoxides to form sulfur-containing block copolymers with readily tunable structures.

关键词： block copolymer polyester polythiocarbonate organocatalysis polymer synthesis

Organocatalytic polymerization

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2019年第9期62卷 1087-1089页

作者： Cheng-Jian zhang xing-hong zhang Key Laboratory of Macromolecular Synthesis and Functionalization (Ministry of Education) Department of Polymer Science and EngineeringZhejiang University

Organocatalysis, defined as the use of small organic molecules for catalyzing chemical transformations, can be traced back more than a century and has become a thriving area over the past 20 years.

关键词： Organocatalytic polymerization organic molecules catalyzing chemical transformations

Neuroprotective effects of acteoside in a glaucoma mouse model by targeting Serta domain-containing protein 4

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第4期17卷 625-637页

作者： Hui-Jie Hao Ya-hong Li Bo Yu Xun Liu Yan zhang Xiao-Li xing Tianjin Key Laboratory of Retinal Functions and Diseases Tianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China

AIM:To explore the therapeutic effect and main molecular mechanisms of acteoside in a glaucoma model in DBA/2J mice.METHODS:Proteomics was used to compare the differentially expressed proteins of C57 and DBA/2J mice.After acteoside administration in DBA/2J mice,anterior segment observation,intraocular pressure(IOP)monitoring,electrophysiology examination,and hematoxylin and eosin staining were used to analyze any potential effects.Immunohistochemistry(IHC)assays were used to verify the proteomics results.Furthermore,retinal ganglion cell 5(RGC5)cell proliferation was assessed with cell counting kit-8(CCK-8)assays.Serta domain-containing protein 4(Sertad4)mRNA and protein expression levels were measured by qRT-PCR and Western blot analysis,respectively.RESULTS:Proteomics analysis suggested that Sertad4 was the most significantly differentially expressed protein.Compared with the saline group,the acteoside treatment group showed decreased IOP,improved N1-P1 wave amplitudes,thicker retina,and larger numbers of cells in the ganglion cell layer(GCL).The IHC results showed that Sertad4 expression levels in DBA/2J mice treated with acteoside were significantly lower than in the saline group.Acteoside treatment could improve RGC5 cell survival and reduce the Sertad4 mRNA and protein expression levels after glutamate injury.CONCLUSION:Sertad4 is differentially expressed in DBA/2J mice.Acteoside can protect RGCs from damage,possibly through the downregulation of Sertad4,and has a potential use in glaucoma treatment.

关键词： glaucoma acteoside Serta domaincontaining protein 4 proteomics mice