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Development and validation of a predictive model for acute-onchronic liver failure after transjugular intrahepatic portosystemic shunt

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1301-1310页

作者： wei Zhang Ya-ni Jin Chang Sun Xiao-Feng Zhang Rui-Qi Li Qin Yin Jin-Jun Chen Yu-Zheng Zhuge Department of Gastroenterology Nanjing Drum Tower HospitalThe Affiliated Hospital of Medical SchoolNanjing UniversityNanjing 210000Jiangsu ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510000Guangdong ProvinceChina Co-first authors:Wei Zhang and Ya-Ni Jin

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is a cause of acute-onchronic liver failure(ACLF).AIM To investigate the risk factors of ACLF within 1 year after TIPS in patients with cirrhosis and construct a prediction *** In total,379 patients with decompensated cirrhosis treated with TIPS at Nanjing Drum Tower Hospital from 2017 to 2020 were selected as the training cohort,and 123 patients from Nanfang Hospital were included in the external validation *** and multivariate logistic regression analyses were performed to identify independent *** prediction model was established based on the Akaike information *** and external validation were conducted to assess the performance of the *** Age and total bilirubin(TBil)were independent risk factors for the incidence of ACLF within 1 year after *** developed a prediction model comprising age,TBil,and serum sodium,which demonstrated good discrimination and calibration in both the training cohort and the external validation *** Age and TBil are independent risk factors for the incidence of ACLF within 1 year after TIPS in patients with decompensated *** model showed satisfying predictive value.

关键词： Acute-on-chronic liver failure Transjugular intrahepatic portosystemic shunt Influencing factor analysis Risk prediction model Nomogram

A Knowledge-enhanced Two-stage Generative Framework for Medical Dialogue Information Extraction

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Machine Intelligence Research 2024年第1期21卷 153-168页

作者： Zefa Hu Ziyi ni Jing Shi Shuang Xu Bo Xu School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China Institute of Automation Chinese Academy of SciencesBeijing 100190China

This paper focuses on term-status pair extraction from medical dialogues(MD-TSPE),which is essential in diagnosis dia-logue systems and the automatic scribe of electronic medical records(EMRs).In the past few years,works on MD-TSPE have attracted increasing research attention,especially after the remarkable progress made by generative ***,these generative methods output a whole sequence consisting of term-status pairs in one stage and ignore integrating prior knowledge,which demands a deeper un-derstanding to model the relationship between terms and infer the status of each *** paper presents a knowledge-enhanced two-stage generative framework(KTGF)to address the above *** task-specific prompts,we employ a single model to com-plete the MD-TSPE through two phases in a unified generative form:We generate all terms the first and then generate the status of each generated *** this way,the relationship between terms can be learned more effectively from the sequence containing only terms in the first phase,and our designed knowledge-enhanced prompt in the second phase can leverage the category and status candidates of the generated term for status ***,our proposed special status"not mentioned"makes more terms available and en-riches the training data in the second phase,which is critical in the low-resource *** experiments on the Chunyu and CMDD datasets show that the proposed method achieves superior results compared to the state-of-the-art models in the full training and low-re-sourcesettings.

关键词： Medical dialogue understanding information extraction text generation knowledge-enhanced prompt low-resource setting dataaugmentation

Metasurface array for single-shot spectroscopic ellipsometry

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Light(Science & Applications) 2024年第5期13卷 835-842页

作者： Shun Wen Xinyuan Xue Shuai Wang Yibo ni Liqun Sun Yuanmu Yang Department of Precision Instrument State Key Laboratory of Precision Measurement Technology and InstrumentsTsinghua UniversityBeijing 100084China

Spectroscopic ellipsometry is a potent method that is widely adopted for the measurement of thin film thickness and refractive *** conventional ellipsometers utilize mechanically rotating polarizers and grating-based spectrometers for spectropolarimetric ***,we demonstrated a compact metasurface array-based spectroscopic ellipsometry system that allows single-shot spectropolarimetric detection and accurate determination of thin film properties without any mechanical *** silicon-based metasurface array with a highly anisotropic and diverse spectral response is combined with iterative optimization to reconstruct the full Stokes polarization spectrum of the light reflected by the thin film with high ***,the film thickness and refractive index can be determined by fitting the measurement results to a proper material model with high *** approach opens up a new pathway towards a compact and robust spectroscopic ellipsometry system for the high throughput measurement of thin film properties.

关键词： properties. spectroscopic film

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新人:“去中心化”的主体及其剩余

文艺理论与批评 2024年第4期 8-12页

作者：倪伟复旦大学中国语言文学系

丁玲向来擅长刻画那种个性倔强的女性人物:她们有着敏锐而丰沛的感受,热烈而深细的情感,以及不屈不挠的意志。早期小说中的梦珂、莎菲,延安时期的陆萍、贞贞,都是这类人物。在自觉转换方向后的《太阳照在桑干河上》中,给人印象深刻的黑... 详细信息

丁玲向来擅长刻画那种个性倔强的女性人物:她们有着敏锐而丰沛的感受,热烈而深细的情感,以及不屈不挠的意志。早期小说中的梦珂、莎菲,延安时期的陆萍、贞贞,都是这类人物。在自觉转换方向后的《太阳照在桑干河上》中,给人印象深刻的黑妮甚至李子俊老婆,也有着类似的特征。这类人物都被放在与社会环境的冲突中来塑造,冲突越尖锐,人物的抗争就越强,其个性也越发鲜明生动。

关键词：《太阳照在桑干河上》早期小说陆萍梦珂莎菲贞贞去中心化女性人物

Impact of wetting-drying cycles and acidic conditions on the soil aggregate stability of yellow‒brown soil

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Journal of Mountain Science 2024年第6期21卷 2075-2090页

作者： XIA Zhenyao ni Yuanzhen LIU Deyu WANG Di XIAO Hai Key Laboratory of Geological Hazards on Three Gorges Reservoir Area Ministry of EducationYichang 443002China College of Civil Engineering&Architecture China Three Gorges UniversityYichang 443002China Engineering Research Center of Eco-environment in Three Gorges Reservoir Region Ministry of EducationChina Three Gorges UniversityYichang 443002China

Soil aggregate is the basic structural unit of soil,which is the foundation for supporting ecosystem functions,while its composition and stability is significantly affected by the external *** study was conducted to explore the effect of external environment(wetting-drying cycles and acidic conditions)on the soil aggregate distribution and stability and identify the key soil physicochemical factors that affect the soil aggregate *** yellow‒brown soil from the Three Gorges Reservoir area(TGRA)was used,and 8 wetting-drying conditions(0,1,2,3,4,5,10 and 15 cycles)were simulated under 4 acidic conditions(pH=3,4,5 and 7).The particle size distribution and soil aggregate stability were determined by wet sieving method,the contribution of environmental factors(acid condition,wetting-drying cycle and their combined action)to the soil aggregate stability was clarified and the key soil physicochemical factors that affect the soil aggregate stability under wetting-drying cycles and acidic conditions were determined by using the Pearson’s correlation analysis,Partial least squares path modeling(PLS‒PM)and multiple linear regression *** results indicate that wetting-drying cycles and acidic conditions have significant effects on the stability of soil aggregates,the soil aggregate stability gradually decreases with increasing number of wetting-drying cycles and it obviously decreases with the increase of ***,the combination of wetting-drying cycles and acidic conditions aggravate the reduction in the soil aggregate *** wetting-drying cycles,acidic conditions and their combined effect imposes significant impact on the soil aggregate stability,and the wetting-drying cycles exert the greatest *** soil aggregate stability is significantly correlated with the pH,Ca^(2+),Mg^(2+),maximum disintegration index(MDI)and soil bulk density(SBD).The PLS‒PM and multiple linear regression analysis further reveal that the soil aggre

关键词： Yellow‒brown soil Wetting-drying cycles Acidic conditions Soil aggregate stability Soil disintegration

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城市建筑题材山水画的笔墨构建

美术 2024年第1期 141-143页

作者：倪巍上海美术学院

城市建筑题材山水画的出现,是在新时代背景下对中国画的绘画自律性因素重新强化和提纯的结果,也使我们得以重新认识和解读传统,证明笔墨的表现力可以超越某种固定模式。笔者结合自身创作实践,尝试指出“城市山水”相对于传统山水在笔墨... 详细信息

城市建筑题材山水画的出现,是在新时代背景下对中国画的绘画自律性因素重新强化和提纯的结果,也使我们得以重新认识和解读传统,证明笔墨的表现力可以超越某种固定模式。笔者结合自身创作实践,尝试指出“城市山水”相对于传统山水在笔墨形态上的变化规律,以及这种自觉的变化对于延续笔墨活性和传统生命力的意义。

关键词：城市山水画中国画建筑题材笔墨

Exploration of Curriculum Ideology and Politics Integrating Medical Humanities Cultivation Model to Enhance Medical Core Values

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Journal of Contemporary Educational Research 2024年第5期8卷 1-7页

作者： Wenjuan ni Ranhao Li Yaqing Guo wei Wang Department of Hematology The First Affiliated Hospital of Baotou Medical CollegeBaotou 014010Inner Mongolia Autonomous RegionChina Department of Endocrinology Ulanqab Central HospitalUlanqab 012000Inner Mongolia Autonomous RegionChina Department of Teaching Management The First Affiliated Hospital of Baotou Medical CollegeBaotou 014010Inner Mongolia Autonomous RegionChina Department of Endocrinology The First Affiliated Hospital of Baotou Medical CollegeBaotou 014010Inner Mongolia Autonomous RegionChina

Purpose:To explore the application effect of the cultivation mode of Curriculum Ideology and Political Integration of Medical Humanities to enhance the core values of medicine in the clinical internship stage of medical ***:Students in the clinical internship stage of the First Affiliated Hospital of Baotou Medical College were selected,and a total of 156 students in one random class in each grade were taken as the observation group and received the integration cultivation mode;148 students were taken as the control group and employed the traditional *** teaching effect of interns in the two groups was ***:The teaching performance of students in both groups after clinical internship teaching was improved compared with that before admission;the teaching performance,teaching effect,teaching evaluation,and teaching satisfaction of the observation group were higher than that of the control ***:The integration of the medical humanities training model with curriculum ideology and politics in the clinical internship of medical students is conducive to the improvement of teaching performance,teaching evaluation,teaching satisfaction of teachers and students,and the development and improvement of core values of medical students,which is of good value for teaching application.

关键词： Curriculum ideology and politics Medical humanities Medical students Core values Clinical internship

Engineering catalytic defects via molecular imprinting for high energy Li-S pouch cells

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National Science Review 2024年第7期11卷 239-251页

作者： Yufei Zhao Chuannan Geng Li Wang Yun Cao Haotian Yang Linkai Peng Xin Jiang Yong Guo Xiaolin Ye wei Lv Quan-hong Yang Shenzhen Geim Graphene Center Engineering Laboratory for Functionalized Carbon Materials Tsinghua Shenzhen International Graduate School Tsinghua University Nanoyang Group Tianjin Key Laboratory of Advanced Carbon and Electrochemical Energy StorageSchool of Chemical Engineering and Technology and Collaborative Innovation Center of Chemical Science and Engineering(Tianjin)Tianjin University Joint School of National University of Singapore and Tianjin University International Campus of Tianjin University

Heterogeneous catalysis promises to accelerate sulfur-involved conversion reactions in lithium-sulfur batteries. Solid-state Li2S dissociation remains as the rate-limiting step because of the weakly matched solid-solid electrocatalysis interfaces. We propose an electrochemically molecular-imprinting strategy to have a metal sulfide（MS） catalyst with imprinted defects in positions from which the pre-implanted Li2S has been electrochemically removed. Such tailor-made defects enable the catalyst to bind exclusively to Li atoms in Li2S reactant and elongate the Li–S bond, thus decreasing the reaction energy barrier during charging. The imprinted ni3S2catalyst shows the best activity due to the highest defect concentration among the MS catalysts examined. The Li2S oxidation potential is substantially reduced to 2.34 V from 2.96 V for the counterpart free of imprinted vacancies, and an Ah-level pouch cell is realized with excellent cycling performance. With a lean electrolyte/sulfur ratio of 1.80 μL mgS–1, the cell achieves a benchmarkedly high energy density beyond 500 Wh kg–1.

关键词： lithium-sulfur battery catalysts defects energy density metal sulfide

Theoretical Modeling and Surface Roughness Prediction of Microtextured Surfaces in Ultrasonic Vibration-Assisted Milling

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 163-183页

作者： Chenbing ni Junjie Zhu Youqiang Wang Dejian Liu Xuezhao Wang Lida Zhu School of Mechanical and Automotive Engineering Qingdao University of TechnologyQingdao 266525China School of Mechanical Engineering and Automation Northeastern UniversityShenyang 110819China

Textured surfaces with certain micro/nano structures have been proven to possess some advanced functions,such as reducing friction,improving wear and increasing *** prediction of micro/nano surface textures is of great significance for the design,fabrication and application of functional textured *** this paper,based on the kinematic analysis of cutter teeth,the discretization of ultrasonic machining process,transformation method of coordinate systems and the cubic spline data interpolation,an integrated theoretical model was established to characterize the distribution and geometric features of micro textures on the surfaces machined by different types of ultrasonic vibration-assisted milling(UVAM).Based on the theoretical model,the effect of key process parameters(vibration directions,vibration dimensions,cutting parameters and vibration parameters)on tool trajectories and microtextured surface morphology in UVAM is ***,the effect of phase difference on the elliptical shape in 2D/3D ultrasonic elliptical vibration-assisted milling(UEVAM)was *** to conventional numerical models,the method of the cubic spline data interpolation is applied to the simulation of microtextured surface morphology in UVAM,which is more suitable for characterizing the morphological features of microtextured surfaces than traditional methods due to the presence of numerous micro *** prediction of surface roughness indicates that the magnitude of ultrasonic amplitude in z-direction should be strictly limited in 1D rotary UVAM,2D and 3D UEVAM due to the unfavorable effect of axial ultrasonic vibration on the surface *** study can provide theoretical guidance for the design and fabrication of microtextured surfaces in UVAM.

关键词： Theoretical modeling Microtextured surface Ultrasonic vibration-assisted milling Cubic spline interpolation Surface roughness