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Hydrodynamic Characteristics of Three-Bucket Jacket Foundation for Offshore Wind Turbines During the Lowering Process

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China Ocean Engineering 2023年第1期37卷 73-84页

作者： ZHANG Pu-yang QI Xin WEI Yu-mo ZHANG Sheng-wei LE Cong-huan DING hong-yan State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China School of Civil Engineering Tianjin UniversityTianjin 300072China

The three-bucket jacket foundation is a new type of foundation for offshore wind turbine that has the advantages of fast construction speed and suitability for deep water. The study of the hoisting and launching process is of great significance to ensure construction safety in actual projects. In this paper, a new launching technology is proposed that is based on the foundation of the three-bucket jacket for offshore wind turbine. A complete time domain simulation of the launching process of three-bucket jacket foundation is carried out by a theoretical analysis combined with hydrodynamic software Moses. At the same time, the effects of different initial air storage and sea conditions on the motion response of the structure and the hoisting cable tension are studied. The results show that the motion response of the structure is the highest when it is lowered to 1.5 times the bucket height. The natural period of each degree of freedom of the structure increases with the increase of the lowering depth. The structural motion response and the hoisting cable tension vary greatly in the early phases of Stages Ⅰ and Ⅲ, smaller in Stage Ⅱ, and gradually stabilize in the middle and late phases of Stage Ⅲ.

关键词： three-bucket jacket foundation time domain simulation hoisting construction motion response offshore wind turbine

Structures and electrochemical performances of as-cast and spun RE-Mg-Ni-Mn-based alloys applied to Ni-MH battery

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Journal of Iron and Steel Research International 2017年第3期24卷 296-305页

作者： yang-huan Zhang Zhong-hui Hou Ying Cai hong-wei Shang Yan Qi Dong-liang Zhao Key Laboratory of Integrated Exploitation of Baiyun Obo Multi-Metal Resources Inner Mongolia University of Science and Technology Department of Functional Material Research Central Iron and Steel Research Institute

The RE-Mg-Ni-Mn-based AB2-type La（1-x）CexMgNi（3.5）Mn（0.5）（ x = 0- 0. 4） alloys were prepared by spinning treatment. For obtaining the optimum performance,the effects of Ce content and spinning rate on the hydrogen storage performance of the alloys were studied systematically. The results show that the variations of the spinning rate and Ce content result in noteworthy changes of the phase content without altering phase composition of the alloys. Specifically,the LaMgNi4 phase increases and LaNi5 phase decreases when increasing the spinning rate and Ce content. Furthermore,the crystalline grains of Cecontaining alloys prepared by spinning treatment are remarkably refined. The alloys own superior electrochemical performance. All alloys reach the optimal discharge capacity at the initial cycle. Increasing Ce content and spinning rate lead the discharge capacity and electrochemical kinetics rise to an optimal value and then start to reduce. Meanwhile,the electrochemical cycle stability is also improved,which is ascribed to the great enhancement of anti-pulverization and anti-corrosion abilities resulting from the spinning treatment and the substitution of Ce for La.

关键词： AB2-type alloy Substitution Spinning treatment Electrochemical kinetics Cycle stability Ni-MH battery

Research progress in Mg-based hydrogen storage alloys

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Rare Metals 2014年第5期33卷 499-510页

作者： Dong-Liang Zhao yang-huan Zhang Department of Functional Material Research Central Iron and Steel Research Institute

Magnesium and magnesium-based alloy hydrides remain attractive hydrogen storage materials owing to high hydrogen capacity and rich reserves in the earth＇s crust. A high stability of hydride and sluggish hydriding/dehydriding kinetics at practical temperatures for the materials drove researchers into alloying with other elements, using different preparation techniques, using catalyst and thin film hydride to improve the hydrogen absorption/desorption properties. In this review, the development of these approaches and their effects on the thermodynamic and kinetics properties of magnesium and magnesium-based alloy hydrides were descript in details.

关键词： Magnesium-based storage alloy Thermodynamic and kinetics Preparation technique Alloying and catalyzing

Morphology control of magnetic properties in cobalt nanowires

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Rare Metals 2023年第6期42卷 1994-1999页

作者： huan-huan Xu Qiong Wu Ming Yue Cheng-Lin Li hong-Jian Li College of Materials Science and Engineering Beijing University of TechnologyBeijing100124China

Cobalt nanowires with different shapes and sizes were synthesized by reduction of carboxylate salts of Co^(Ⅱ) in 1,2-butanediol using a solvothermal chemical *** well-crystallized Co nanowires with hexagonal closepacked(hep) phase are observed and the(002) crystalline direction is along the long axis of nano *** morphology control is strongly dependent on the reaction *** varying the amount of capping agent in proper ranges,the effect of reaction parameters on controlling the size and shape of Co nanowires is *** the amount of capping agent increasing,the aspect ratio of Co nanowires increases ***,the magnetic measurement of cobalt nanowires shows that the coercivity of the Co nanocrystals does not increase with the increase in aspect ratio monotonously,which suggests that the tip shape and micros tructure also play an important role in the magnetization reversal process of the Co nanocrystals,and the aspect ratio plays a much less role as the ratio value exceeds *** further understand the effect of size on the magnetic properties in the Co nanowires,micromagnetic simulations were performed,which confirms that the magnetic properties are barely affected by the aspect ratio larger than *** highest coercivity of624 kA·m^(-1) is obtained for ellipsoid nano wires with a mean length of 200 nm,which also displays a strong magnetic *** a result,the highest energy product of the wires reaches 248 kJ·m^(-3).

关键词： Co nanowires Morphology control Tip shape High energy product

Baicalin Antagonizes Prostate Cancer Stemness via Inhibiting Notch1/NF-κB Signaling Pathway

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Chinese Journal of Integrative Medicine 2023年第10期29卷 914-923页

作者： WU Ming-hui WU Kun ZHU Yuan-bing LI Da-chuan yang huan ZENG hong Department of Urology Hubei University of Traditional Chinese MedicineWuhan430065China Department of Urology Chongqing Jiangjin District Hospital of Chinese MedicineChongqing402260China

Objective To investigate the molecular mechanisms underlying the effect of baicalin on prostate cancer(PCa)progression both in vivo and in *** The in situ PCa stem cells(PCSCs)-injected xenograft tumor models were established in BALB/c nude *** volume and weight were respectively checked after baicalin(100 mg/kg)***-eosin(HE)staining was used to observe the growth arrest and cell *** expression levels of acetaldehyde dehydrogenase 1(ALDH1),CD44,CD133 and Notch1 were determined by reverse transcription-polymerase chain *** expression levels of ALDH1,CD44,CD133,Notch1,nuclear factorκB(NF-κB)P65 and NF-κB p-P65 were detected by Western *** and subcellular location of ALDH1,CD44,CD133,Notch1 and NF-κB p65 were detected by immunofluorescence *** vitro,cell cycle distribution and cell apoptosis of PC3 PCSCs was assessed by flow cytometry after baicalin(125µmol/L)*** migration and invasion abilities of PCSCs were assessed using Transwell *** electron microscopy scanning was utilized to observe the structure and autophagosome formation of baicalin-treated *** addition,PCSCs were infected with lentiviruses expressing human *** Compared with the control group,the tumor volume and weight were notably reduced in mice treated with 100 mg/kg baicalin(P<0.05 or P<0.01).Histopathological analysis showed that baicalin treatment significantly inhibited cell proliferation and promoted cell ***,baicalin treatment reduced mRNA and protein expression levels of CD44,CD133,ALDH1,and Notch1 as well as the protein expression of NF-κB p-P65 in the xenograft tumor(P<0.01).In vitro,the cell proliferation of PCSCs was significantly attenuated after treatment with 125µmol/L baicalin for 72 h(P<0.01).The cell migration and invasion rates were decreased following treatment with baicalin for 48 and 72 h(P<0.01).Baicalin notably induced cell apoptosis and seriously

关键词： baicalin prostate cancer cancer stemness Notch1/nuclear factorκB signaling

耐力训练大鼠抗动脉粥样硬化线粒体自噬通路中抗增殖蛋白2的作用

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中国组织工程研究 2025年第11期29卷 2294-2300页

作者：宋明箫陈君顺子王宁伟蔡欢冯红天津体育学院运动健康学院天津市301617 贵阳学院体育学院贵州省贵阳市550005

背景:运动可降低血脂,减缓动脉粥样硬化发展。动脉粥样硬化起始于线粒体功能障碍,而抗增殖蛋白2蛋白受耐力训练调控,参与线粒体自噬。目的:验证耐力训练干预动脉粥样硬化中抗增殖蛋白2蛋白在线粒体自噬通路中的作用。方法:将40只Wistar... 详细信息

背景:运动可降低血脂,减缓动脉粥样硬化发展。动脉粥样硬化起始于线粒体功能障碍,而抗增殖蛋白2蛋白受耐力训练调控,参与线粒体自噬。目的:验证耐力训练干预动脉粥样硬化中抗增殖蛋白2蛋白在线粒体自噬通路中的作用。方法:将40只Wistar大鼠随机分为对照组、运动组、动脉粥样硬化组和动脉粥样硬化运动组,每组10只,后2组大鼠高脂饮食(9周)联合维生素D注射(第1,3,6周)构建大鼠动脉粥样硬化模型,同时2个运动组大鼠进行跑台递增训练干预9周。干预结束后进行血脂和病理检测观察造模及干预效果;酶标法和Western blot检测线粒体膜电位和自噬相关蛋白表达;免疫荧光观察主动脉中线粒体自噬蛋白的共定位情况。结果与结论:(1)血脂和病理切片显示,与动脉粥样硬化组相比,动脉粥样硬化运动组大鼠血清低密度脂蛋白胆固醇、总胆固醇水平和主动脉脂质沉积面积显著降低(P<0.001)。(2)线粒体膜电位显示,动脉粥样硬化运动组大鼠主动脉线粒体膜电位的显著降低得到逆转(P<0.01)。(3)Western blot显示,与对照组相比,动脉粥样硬化组大鼠线粒体抗增殖蛋白2、LC3Ⅱ/Ⅰ、PINK1和Parkin蛋白表达显著升高(P<0.05),PARL和PGAM5蛋白表达降低(P<0.05);与动脉粥样硬化组相比,动脉粥样硬化运动组大鼠线粒体PINK1和Parkin蛋白表达显著降低(P<0.05),抗增殖蛋白2、LC3Ⅱ/Ⅰ、PARL和PGAM5蛋白表达显著升高(P<0.05)。(4)免疫荧光结果显示,动脉粥样硬化组较对照组LC3和PINK1与TOMM20共定位显著增加(P<0.05),动脉粥样硬化运动组较动脉粥样硬化组LC3与TOMM20共定位显著增加(P<0.05);动脉粥样硬化组较对照组LC3和PARL与抗增殖蛋白2共定位显著增加(P<0.01),动脉粥样硬化运动组较动脉粥样硬化组LC3与抗增殖蛋白2共定位显著增加(P<0.01),PARL蛋白与抗增殖蛋白2共定位显著降低(P<0.01)。(5)结果表明,耐力训练可诱导线粒体内膜自噬受体抗增殖蛋白2表达,促进抗增殖蛋白2与线粒体自噬接头蛋白的结合完成线粒体自噬,恢复线粒体功能,减缓动脉粥样硬化发生。

关键词：抗增殖蛋白2 耐力训练线粒体自噬动脉粥样硬化线粒体

Changes of Anti-tuberculosis Herbs Formula during Past Three Decades in Contrast to Ancient Ones

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Chinese Journal of Integrative Medicine 2021年第5期27卷 388-393页

作者： XU Yu-hui Dai Guang-ming TANG Shi-huan yang hong-jun SUN Zhao-gang Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China Translational Medicine Center Beijing Chest HospitalCapital Medical UniversityBeijing 101149China Beijing Key Laboratory in Drug Resistant Tuberculosis Research Beijing Tuberculosis&Thoracic Tumor Research InstituteBeijing 101149China

Objective:To investigate the evolution of herbal medicine in treating tuberculosis(TB)and encourage anti-TB drug discovery and ***:In this study,477 ancient traditional Chinese medicine formulae were collected from the Dictionary of Traditional Chinese Medicine Prescriptions and 172 modern Chinese medicine formulae(from 1986 to 2016)were collected by searching 4 databases:Wan Fang Data Knowledge Service Platform,China National Knowledge Infrastructure Database(CNKI),China Science and Technology Journal Database(VIP)and Chinese Bio-medical Literature and Retrieval System(Sino Med)in *** restricted the search to publications in *** data analysis was done using the Traditional Chinese Medicine Inheritance Support System version 2 ***:There were 425 herbs in the 477 ancient formulae and 257 herbs in the 172 modern *** of the top 30 herbs were shared by both modern and ancient *** are Radix Ophiopogonis,Astragalus membranaceus,Fritillaria cirrhosa,Dried rehmannia glutinosa,Poria cocos,Angelica sinensis,Prepared rehmannia glutinosa,Platycodon Root,Radix paeoniae alba,Schisandra chinensis,Bighead atractylodes rhizome,Rhizoma anemarrhenae,Cortex lycii radicis and Radix *** two groups of herbs with a high correlation coefficient were found in both modern and ancient prescriptions,the Dried rehmannia glutinosa with Radix ophiopogonis,and Radix ophiopogonis with Prepared rehmannia *** were 9 and 15 core herb combinations in modern and ancient prescriptions,respectively,but no one was found simutaniously in both modern and ancient ***:Although there were wide variations in the herb groups and herb combinations in the formulae,half of the top 30 herbs were found in both modern and ancient *** core herb combinations in modern and ancient prescriptions could help us to improve the priscription for treatment of TB.

关键词： herbal formula tuberculosis Chinese materia medica anti-tuberculosis herbs

Hermite interpolation and its numerical differentiation formula involving symmetric functions

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Applied Mathematics(A Journal of Chinese Universities) 2009年第3期24卷 309-314页

作者： BAI hong-huan XU Ai-min Department of Mathematics Zhejiang University Hangzhou 310027 China Institute of Mathematics Zhejiang Wanli University Ningbo 315100 China

By utilizing symmetric functions,this paper presents explicit representations for Hermite interpolation and its numerical differentiation *** the corresponding error estimates are also provided.

关键词： Hermite interpolation numerical differentiation elementary symmetric function complete symmetric function

A Variational ODE and its Application to an Elliptic Problem

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Acta Mathematicae Applicatae Sinica 2007年第4期23卷 685-696页

作者： huan-song Zhou hong-bo Zhu Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences P.O. Box 71010 Wuhan 430071 China

In this paper, we consider the following ODE problem { （-u＂（τ）＋（N-1）（N-3）/4τ^2 ）u（τ）＋λu（τ）=f（τ,τ（1-N）/2 u）u（τ）,τ〉0, u∈H, N≥3. （P）,where f ∈ C（（0,＋∞） ×R,R）, f（τ,s） goes t... 详细信息

In this paper, we consider the following ODE problem { （-u＂（τ）＋（N-1）（N-3）/4τ^2 ）u（τ）＋λu（τ）=f（τ,τ（1-N）/2 u）u（τ）,τ〉0, u∈H, N≥3. （P）,where f ∈ C（（0,＋∞） ×R,R）, f（τ,s） goes to p（τ） and q（τ） uniformly in τ 〉 0 as s→ 0 and s→＋∞ respectively, 0≤ p（τ） ≤ q（τ） ∈L^∞（0,∞）. Moreover, for τ 〉 0, f（τ, s） is nondecreasing in s≥ 0. Some existence and non-existence of positive solutions to problem （P） are proved without assuming that p（τ） = 0 and q（τ） has a limit at infinity. Based on these results, we get the existence of positive solutions for an elliptic problem.

关键词： Elliptic equation asymptotically linear mountain pass theorem