检索结果-南通市图书馆

Oral health status in Sichuan Province: findings from the oral health survey of Sichuan, 2015–2016

在线全文

学校读者我要写书评

暂无评论

International Journal of Oral Science 2017年第1期9卷 10-15页

作者： Wei Yin Ying-Ming Yang hong Chen Xue Li Zhuo Wang Li Cheng Qiu-Dan Yin hong-zhi fang Wei Fei fang-Lin Mi Min-Hai Nie Tao Hu Xue-Dong Zhou State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesDepartment of Preventive DentistryWest China Hospital of StomatologySichtJan UniversityChengduChina Sichuan Center for Disease Control and Prevention ChengduChina The Third People's Hospital of Chengdu ChengduChina Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital ChengduChina Department of Stomatolosy North Sichuan Medical CollegeFirst Affiliated HospitalNanchongChina Department of Stomatology Southwest Medical UniversityLuzhouChina and State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesWest China Hospital of StomatolosySichuan UniversityChengduChina

To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organization. A multistage stratified random cluster-sampling method was used to enroll participants from the following three groups： children aged 3-5 years, adolescents aged 12 years, and people aged 65-74 years. In these three groups, the mean numbers of teeth that were affected by caries were 3.28, 0.86 and 5.13, respectively, resulting in a prevalence of 63.47%, 37.20% and 83.20%, respectively. Relative to the high rate of decayed teeth, the prevalence of fillings was very low in all age groups （0.97%, 7.24% and 5.43%, respectively）, In the 12-year-old adolescent group, only 3.61% had good pit and fissure sealing. In addition, the rate of dental fluorosis was 24.80%, and the Community Fluorosis Index value was 0.39. In the elder group, the community periodontal index was 2.92. The prevalence in the elderly of having lost at least one tooth was 75.54%. Additionally, 4.44% of these participants were edentulous. The incidence of dental prosthesis was 51.75%, the proportion with a removable partial denture, a fixed denture, full dentures, dental implants and an informal fixed bridge was 21.59%, 11.45%, 4.64%, 0 and 16.67%, respectively. In this study, 8.2% of the elderly participants were affected by different types of oral mucosal lesions. Among such lesions, recurrent aphthous ulcers were most prevalent （2.69%） and oral lichen planuses were second （1.6%）. The conclusion presented in this survey is that oral diseases, especially dental caries and periodontal disease, are frequent and common in Sichuan province, China. Moreover, the treatment rate is very low, and primary prevention and treatment options are therefore urgently needed in this population.

关键词： cross-sectional study dental caries oral health status periodontal condition Sichuan Province of China

An in vitro study on the efficacy of removing calcium hydroxide from curved root canal systems in root canal therapy

在线全文

学校读者我要写书评

暂无评论

International Journal of Oral Science 2017年第2期9卷 110-116页

作者： Ying Wang Li-Yang Guo hong-zhi fang Wen-Ling Zou Ying-Ming Yang Yuan Gao Hui Yang Tao Hu State Key Laboratory of Oral Disease National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China Department of Endodontics The Affiliated Stomatology Hospital School of Medicine Zhejiang University Hangzhou China Department of Stomatology The Third People's Hospital of Chengdu Chengdu China State Key Laboratory of Oral Disease National Clinical Research Center for Oral Diseases Department of Preventive Dentistry West China Hospital of Stomatology Siehuan University Chengdu China State Key Laboratory of Oral Disease National Clinical Research Center for Oral Diseases Department of General Dentistry West China Hospital of Stomatology Sichuan University Chengdu China

To compare the efficacy of various irrigants(citric acid, ethylenediaminetetraacetic acid(EDTA) and Na OCl) and techniques in removing Ca(OH)2in two types of curved root canal systems, simulated root canals with specific curvatures were used to investigate the effects of different irrigants and instruments on Ca(OH)2removal. The optimal methods were verified on extracted human teeth. Simulated root canals were assigned to one of two groups based on the irrigation solution: 10% citric acid or2.5% Na OCl. Each group was divided into four subgroups according to the technique used to remove Ca(OH)2. The percentage of Ca(OH)2removal in different sections of root canals was calculated. On the basis of the results obtained for the simulated canals, 10% citric acid and 17% EDTA were applied to remove Ca(OH)2from the extracted human teeth with curved root canal systems. The teeth were scanned by micro computed tomography to calculate the percentage of Ca(OH)2removal in the *** simulated root canals, we found that 10% citric acid removed more Ca(OH)2than 2.5% NaOCl in the 0–1 mm group from the apex level(Po0.05). Ultrasonic and Endo Activator activation significantly removed more Ca(OH)2than a size 30 K file in the apical third(Po0.05). However, there were no significant differences in any sections of the canals for 10% citric acid or 17%EDTA in removing Ca(OH)2in extracted human teeth. We concluded that it was effective to remove residual Ca(OH)2using the decalcifying solution with Endo Activator or Passive Ultrasonic Irrigation in a curved root canal system. A protocol for Ca(OH)2removal was provided based on the conclusions of this study and the methods recommended in previous studies.

关键词： calcium hydroxide curved root canal system irrigation removal

Blockage of IGF-1R signaling sensitizes urinary bladder cancer cells to mitomycin-mediated cytotoxicity

在线全文

学校读者我要写书评

暂无评论

Cell Research 2001年第2期11卷 107-115页

作者： SUN hong zhi, SHU fang WU, ZENG hong TU Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Istrel. Tel: 009728-9343182. E-mail: hongzhi@wicc.weizmann.ac.il Fax: 00972-8-9344116 State Key Laboratory of Drug Research, Shang Department of Biological Regulation Weizmann Institute of Science Rehovot Israel State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China

A major problem which is poorly understood in the management of bladder cancer is low sensitivity to chemotherapy and high recurrence after transurethral resection. Insulin-like growth factor 1 receptor (IGF-1R) signaling plays a very important role in progression, invasion and metastasis of bladder cancer cells. In this study, we investigated whether IGF-1R was involved in the growth stimulating activity and drug resistance of bladder cancer cells. The results showed: The mRNAs of IGF-1, IGF-2 and IGF-1R were strongly expressed in serum-free cultured T24 cell line, whereas normal urothelial cells did not express these factors/receptors or only in trace leve1s; T24 cell responded far better to growth stimulation by IGF-1 than did normal urothelial cells; blockage of IGF1R by antisense oligodeoxynucleotide (ODN) significantly inhibited the growth of T24 cell and enhanced sensitivity and apoptosis of T24 cells to mitomycin (MMC). These results suggested that blockage of IGF-IR signaling might potentially contribute to the treatment of bladder cancer cells which are insensitive to chemotherapy.

关键词： IGF-1R signaling autocrine drug resistance apoptosis transitional cell carcinoma.

The effect of long-term traditional Chinese medicine treatment on disease-free survival of postoperative stage I-III lung cancer patients:a retrospective cohort study

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2019年第2期4卷 91-98页

作者： Su-Tong Liu Su-fang Zhang Kai-Qi Su Ying-Bin Luo zhi-hong fang Yuan fang Jing Xu Jian-Chun Wu Yan Li Department of Oncology Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Shanghai China Department of Traditional Chinese and Western Medicine Shanghai Pulmonary Hospital of Tongji University School of Medicine Shanghai China. Shanghai University of Traditional Chinese Medicine Shanghai China

Objective:Traditional Chinese medicine(TCM)has been extensively used as one of popular alternative therapies for several ***,it remains unclear whether TCM treatment is associated with longer survival in lung cancer *** this study,we explored the effect of long-term TCM treatment on patients with different stages of lung ***:All information of lung cancer patients with stage I-III disease from January 2007 to September 2015 was collected for this retrospective cohort *** who were treated with TCM after surgery were divided into TCM group and the others were into the non-TCM group(control group).All patients were regularly followed up by clinic appointment or phone,and all survival data were collected from databases after the last follow-up in October ***:A total of 575 patients were included in this study,with 299 patients in the TCM group and 276 in the control *** all patients,5-year disease-free survival(DFS)was 62.2% in TCM group and 42.1% in the control group,and 6-year DFSs were 51.8% and 35.4%,respectively(HR=0.51,95% CI:0.40 to 0.66,log-rank P≤0.001).For patients with stage I,5-year DFSs were 83.7%(TCM group)and 57.5%(control group)and 6-year DFSs were 73.7% and 51.9%,respectively(HR=0.30,95% CI:0.18 to 0.50,log-rank P≤0.001).For patients with stage II in the TCM group and the control group,5-year DFSs were 59.4% and 17.6% and 6-year DFSs were 44.7% and 17.6%,respectively(HR=0.31,95% CI:0.19 to 0.52,log-rank P≤0.001),and for patients with stage III,5-year and 6-year DFSs in the TCM group were 18.7% and 12.5% compared with 28.4% and 20.3% in the control group(HR=1.06,95% CI:0.72 to 1.56,log-rank P=0.76).Conclusions:This study demonstrated that long-term TCM treatment as an adjuvant therapy is able to improve the DFS of postoperative stage I-III lung cancer patients,especially in patients with stage I and II ***,these observational findings need being validated by large sample randomized control

关键词： Traditional Chinese medicine Lung cancer Disease-free survival Retrospective study Cohort study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

离子束诱变活性污泥辅助处理焦化废水的研究

合肥工业大学学报（自然科学版） 2007年第6期30卷 672-675,680页

作者：洪志方牛漫兰合肥工业大学资源与环境工程学院安徽合肥230009

应用离子束为诱变因素,对活性污泥进行辐照处理,研究经驯化培育后,处理一定浓度的焦化废水的结果表明:活性污泥的性能及数量的评价指标、生化指标、污泥增长率以及与污染负荷等有明显的变化,经离子束照射处理后活性污泥的SV30值为11.0%~... 详细信息

应用离子束为诱变因素,对活性污泥进行辐照处理,研究经驯化培育后,处理一定浓度的焦化废水的结果表明:活性污泥的性能及数量的评价指标、生化指标、污泥增长率以及与污染负荷等有明显的变化,经离子束照射处理后活性污泥的SV30值为11.0%~14.0%,SVI值为34.97~42.02 mL/g,辐照后的活性污泥SVI值低于未辐照活性污泥的SVI值,MLSS值在2 940~3 515 mg/L,污泥增长率变化范围为17.17%^-2.00%,最佳CODcr去除率为92.17%,最佳氨氮去除率可达到94.64%,挥发酚去除率效果最好,可达到99.83%,处理效果优于未辐照前。

关键词：活性污泥诱变离子束焦化废水处理

神经特异性烯醇化酶表达与重症肠道病毒71型感染患儿预后的关系

在线全文

学校读者我要写书评

暂无评论

中华医院感染学杂志 2016年第23期26卷 5488-5490页

作者：任志红方凌湖北省黄冈市中心医院小儿内科湖北黄冈438000

目的明确重症肠道病毒71型感染患儿预后与神经特异性烯醇化酶表达的关系。方法选取2014年2月-2015年6月医院收治的肠道病毒71型重症感染患儿76例,比较预后良好与预后较差患儿血清神经特异性烯醇化酶水平,计算神经特异性烯醇化酶评估患... 详细信息

目的明确重症肠道病毒71型感染患儿预后与神经特异性烯醇化酶表达的关系。方法选取2014年2月-2015年6月医院收治的肠道病毒71型重症感染患儿76例,比较预后良好与预后较差患儿血清神经特异性烯醇化酶水平,计算神经特异性烯醇化酶评估患儿预后的灵敏度、特异度和相对危险度。结果 76例重症肠道病毒71型感染患儿,GOS 1~3分患儿34例,GOS 4~5分患儿42例,神经特异性烯醇化酶分别为（37.27±8.62）μg/L、（18.31±4.78）μg/L;以血清神经特异性烯醇化酶30μg/ml为标准评估重症肠道病毒71型感染患儿预后,灵敏度为70.59%,特异度为76.19%,相对危险度为1.94。结论神经特异性烯醇化酶与重症肠道病毒71型患儿的预后具有明显相关性,其浓度越高,患儿预后越差,可作为评估预后的参考指标。

关键词：神经特异性烯醇化酶重症肠道病毒71型预后

在线全文

学校读者我要写书评

暂无评论

胃癌术后单纯骨骼肌转移1例

世界华人消化杂志 2016年第26期24卷 3837-3840页

作者：向卉楠方媛方志红上海中医药大学附属市中医医院肿瘤科上海市200071

胃癌转移一般以淋巴转移和腹腔脏器转移为主,较少侵及骨骼肌.本文报道了胃癌术后单纯骨骼肌转移1例,探讨了胃癌术后骨骼肌转移的发病机理、诊断方法及预后转归.

关键词：骨骼肌转移胃癌术后误诊

Lightweight Al-Nb-Ti-V-Cr high entropy alloys with high hardness and enhanced mechanical properties via doping Co

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2025年

作者： fang-dong Xu De-zhi Chen Rui-run Chen Bin Gan Jing-yue Yu National Key Laboratory for Precision Hot Processing of Metals Harbin Institute of Technology Suzhou Laboratory

To develop high-hardness and high-strength lightweight high entropy alloys （LHEAs）,a series of CoxAlNbTiVCr alloys were *** phase constitution,distribution,and crystal structure of the Laves phase in alloys can be altered by adjusting the composition of HEAs,which in turn influences their mechanical *** Nb Ti VCr （x=0,0.5,1,1.5,and 2,atomic ratio percentage） LHEAs were designed and prepared to characterize the microstructure and tailor the mechanical *** introduction of Co changes the microstructure of LHEAs from a single B2 structure to a mixture dendrite structure,which consists of B2 phase,C14 and C15 Laves *** the C14 and C15 Laves phases exhibit coupled *** parameters including mixing enthalpy (ΔHmix),valence electron concentration （VEC）,atomic radius size （δ）,mixing entropy （ΔS）,and electronegativity difference （Δχ） are used to predict the formation of B2 and Laves phase in *** the Co content increases from 0 to 1.5at.%,Laves phase volume fraction gradually increases,which leads to an enhancement in the compressive strength from 1,520.8 MPa to 1,844.4 ***1.5Al Nb Ti VCr alloy exhibits the maximum Vickers hardness of 699.4 *** improvement of mechanical properties mainly originates from solid solution strengthening and second phase strengthening.

关键词：

基于半轮询驱动的网络入侵检测单元的设计与实现

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

通信学报 2004年第7期25卷 146-152页

作者：田志宏方滨兴张宏莉哈尔滨工业大学国家计算机信息内容安全重点实验室黑龙江哈尔滨150001

在分析了网络入侵检测系统主要问题的基础上,设计并实现了一个面向网络的入侵检测单元NIDU。由于采用对等式架构,NIDU具有良好的可扩展性。提出了半轮询驱动的概念,利用半轮询驱动机制降低了系统中断频率,明显提高数据采集能力;同时采... 详细信息

在分析了网络入侵检测系统主要问题的基础上,设计并实现了一个面向网络的入侵检测单元NIDU。由于采用对等式架构,NIDU具有良好的可扩展性。提出了半轮询驱动的概念,利用半轮询驱动机制降低了系统中断频率,明显提高数据采集能力;同时采用基于相关度的异常检测技术,对DoS和DDoS攻击的检测效果较现有方法有明显改善。

关键词：入侵检测半轮询驱动相关度通信协议