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Strain Mesorhizobium ***035:A Stress-Tolerant Isolate from Glycyrrhiza glabra Displaying a Wide Host Range of Nodulation

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Pedosphere 2008年第1期18卷 102-112页

作者： WEI Ge-hong yang xue-Ying ZHANG Zhi-Xin yang Ya-Zhen K. LINDSROM Shaanxi Key Laboratory of Molecular Biology for Agriculture College of Life Science Northwest A＆F University Yangling Shaanxi 712100 （China） Department of Applied Chemistry and Microbiology Biocenter 1 Fin-0014 University of Helsinki （Finland）

Thirty-nine rhizobial isolates were isolated from the root nodules of Glycyrrhiza uralensis and Glyeyrrhiza glabra, growing in the arid and semiarid regions of northwestern China, to test their taxonomic position and stress tolerance and to select one promising putative inoeulant strain for further studies. On the basis of 113 physiological and biochemical characteristics, the isolates were clustered into three groups. One isolate CCNWGX035 was found to have high tolerance to NaC1, pH, and temperature. By sequencing the 16S rDNA, isolate CCNWGX035 was placed in genus Mesorhizobium. Nodulation tests demonstrated that the isolate not only formed nitrogen-fixing nodules on its original host plant Glyeyrrhiza glabra, but also on Sophora vieiifolia, Lotus cornieulatus, Trifolium repens, Melilotus suaveolens, and Sophora alopecuroides. On the basis of sequence analysis of the nodA gene, isolate CCNWGX035 was closely related to strains of the genus Mesorhizobium, exhibiting some novel characteristics of root nodule bacteria.

关键词： Glycyrrhiza host range Mesorhizobium nodA stress tolerance

Genome-Wide Analysis Regulatory Network of Photomorphogenesis Revealed the Complex Brassinosteroid Effects in

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Molecular Plant 2009年第4期2卷 755-772页

作者： Li Song Xiao-Yi Zhou Li Li Liang-Jiao xue Xi yang hong-Wei xue National Key Laboratory of Plant Molecular Genetics Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 300 Fenglin Road 200032 Shanghai China

Light and brassinosteroids （BRs） have been proved to be crucial in regulating plant growth and development; however, the mechanism of how they synergistically function is still largely unknown. To explore the underlying mechanisms in photomorphogenesis, genome-wide analyses were carried out through examining the gene expressions of the dark-grown WT or BR biosynthesis-defective mutant det2 seedlings in the presence of light stimuli or exogenous Brassinolide （BL）. Results showed that BR deficiency stimulates, while BL treatment suppresses, the expressions of lightresponsive genes and photomorphogenesis, confirming the negative effects of BR in photomorphogenesis. This is consistent with the specific effects of BR on the expression of genes involved in cell wall modification, cellular metabolism and energy utilization during dark-light transition. Further analysis revealed that hormone biosynthesis and signaling-related genes, especially those of auxin, were altered under BL treatment or light stimuli, indicating that BR may modulate photomorphogenesis through synergetic regulation with other hormones. Additionally, suppressed ubiquitin-cycle pathway during light-dark transition hinted the presence of a complicated network among light, hormone, and protein degradation. The study provides the direct evidence of BR effects in photomorphogenesis and identified the genes involved in BR and light signaling pathway, which will help to elucidate the molecular mechanism of plant photomorphogenesis.

关键词： brassinosteroid light photomorphogenesis hormone interplay ubiquitin.

Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)

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Military Medical Research 2020年第3期7卷 249-282页

作者： Ying-Hui Jin Qing-Yuan Zhan Zhi-Yong Peng xue-Qun Ren Xun-Tao Yin Lin Cai Yu-Feng Yuan Ji-Rong Yue Xiao-Chun Zhang Qi-Wen yang Jianguang Ji Jian Xia Yi-Rong Li Fu-Xiang Zhou Ya-Dong Gao Zhui Yu Feng Xu Ming-Li Tu Li-Ming Tan Min yang Fang Chen Xiao-Ju Zhang Mei Zeng Yu Zhu Xin-Can Liu Jian yang Dong-Chi Zhao Yu-Feng Ding Ning Hou Fu-Bing Wang Hao Chen Yong-Gang Zhang Wei Li Wen Chen Yue-Xian Shi Xiu-Zhi yang xue-Jun Wang Yan-Jun Zhong Ming-Juan Zhao Bing-Hui Li Lin-Lu Ma Hao Zi Na Wang Yun-Yun Wang Shao-Fu Yu Lu-Yao Li Qiao Huang hong Weng Xiang-Ying Ren Li-Sha Luo Man-Ru Fan Di Huang hong-yang xue Lin-Xin Yu Jin-Ping Gao Tong Deng Xian-Tao Zeng hong-Jun Li Zhen-Shun Cheng Xiao-Mei Yao Xing-Huan Wang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Respiratory Diseases China-Japan Friendship HospitalBeijing 100029China Department of Pulmonary and Critical Care Medicine China-Japan Friendship HospitalBeijing 10029China Leishenshan Hospital in Wuhan Wuhan 430200China Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institutes of Evidence-based Medicine and Knowledge Translation Henan UniversityKaifeng 475000HenanChina Department of Medical Imaging Guizhou Provincial People’s HospitalGuiyang 550002China Departments of Orthopedics Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Clinical Laboratory Peking Union Medical College Hospital(PUMCH)Peking Union Medical CollegeChinese Academy of Medical Sciences(CAMS)Beijing 100730China Center for Primary Health Care Research Lund University and Region Skåne25002 MalmöSweden Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 403371China Department of Allergology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan 43071China Department of Critical Care Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Emergency Medicine and Chest Pain Center Qilu Hospital of Shandong UniversityJinan 250002China Department of Respiratory and Critical Care Medicine Suizhou Central HospitalHubei University of MedicineSuizhou 441300HubeiChina Department of Clinic Pharmacy Second People’s Hospital of Huaihua Ci

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the *** and treatment guidelines for clinicians caring for patients are *** the early stage,we have issued"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)";now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based *** formed a working group of clinical experts and *** steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge *** searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)*** were either strong or weak,or in the form of ungraded consensus-based ***,we issued 34 *** them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based *** covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung

关键词： COVID-19 SARS-CoV-2 Recommendation Chemoprophylaxis Diagnosis Treatment Discharge management Traditional Chinese medicine guideline

基于Ad hoc网络的煤矿应急井下救灾通信技术分析

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煤炭技术 2013年第6期32卷 84-86页

作者：赵凯杨洪雪北京电子科技职业学院北京100015

煤矿井下应急救灾通信系统的构建对于救援工作的实施具有重要作用。文章分析了Ad hoc网络的特点与井下救援工作的需求,针对通信模型的构建以及需要解决的一些关键问题进行了研究,希望能为煤矿井下救援工作的顺利推进和救援质量、效率的... 详细信息

煤矿井下应急救灾通信系统的构建对于救援工作的实施具有重要作用。文章分析了Ad hoc网络的特点与井下救援工作的需求,针对通信模型的构建以及需要解决的一些关键问题进行了研究,希望能为煤矿井下救援工作的顺利推进和救援质量、效率的提升提供参考。

关键词： Ad Hoc网络井下应急救援救灾通信

Earthquake, strong tide and global low temperature

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Global Geology 2005年第Z1期 126-132页

作者： yang Dong-hong, yang xue-xiang College of Geo-Exploration Science and Technology, Jilin University, Changchun 130026, Jilin, China National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012, Jilin, China

" La Madre " is a kind of upper atmospheric air current, and occurs as " warm phase " and " cold phase " in the sky of Pacific Ocean alternately. There exists this phenomenon, called " Oscillation Decade in the Pacific" (ODP), for 20-30 years. It is concerned with 60 year cycle of the tides. Lunar oscillations explain an intriguing 60-year cycle in the world's temperature. Strong tides increase the vertical mixing of water in the oceans, drawing cold ocean water from the depths to surface, where it cools the atmosphere above. The first strong seismic episode in China was from 1897 to 1912; the second to the fifth was the in1920-1937, 1946-1957, 1966-1980, 1991-2002, tsrectruely. The alternative boundaries of "La Madre " warm phase and cold phase were in 1890, 1924, 1946 and 2000, which were near the boundaries of four strong earthquakes. It indicated the strong earthquakes closedly related with the substances' motion of atmosphere, hydrosphere and lithosphere, the change of gravity potential, and the exchange of angular momentum. The strong earthquakes in the ocean bottom can bring the cool waters at the deep ocean up to the ocean surface and make the global climate cold, the earthquake, strong tide and global low temperature are close inrelntion for each othen.

关键词： earthquake tsunami low temperature Pacific Decade Oscillation strong tides

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祁连山水源涵养林土壤水文特征研究

林业科学研究 2006年第1期19卷 39-44页

作者：党宏忠周泽福赵雨森杨洪学中国林业科学研究院林业研究所东北林业大学林学院黑龙江哈尔滨150040

通过对祁连山水源涵养林区的苔藓-青海云杉林、亚高山灌丛、灌木-青海云杉林、中低山灌木林和祁连圆柏以及牧草地等6种植被土壤水分物理性质的测定与计算,比较分析了不同植被的水源涵养能力,建立了主要土壤类型的入渗模型、土壤水分消... 详细信息

通过对祁连山水源涵养林区的苔藓-青海云杉林、亚高山灌丛、灌木-青海云杉林、中低山灌木林和祁连圆柏以及牧草地等6种植被土壤水分物理性质的测定与计算,比较分析了不同植被的水源涵养能力,建立了主要土壤类型的入渗模型、土壤水分消退方程,评价了不同植被土壤层水文特征及其与植被间的关系。祁连山区主要森林的平均土壤密度均小于1 g·cm-3,土壤的蓄水能力很强但各植被间差异较大。各种森林植被土壤均表现出较高的入渗性能,土壤初渗率、稳渗率及蓄水能力从大到小的次序均为:苔藓-青海云杉林、亚高山灌丛、灌木-青海云杉林、中低山灌木林、祁连圆柏林和牧草地。在相同的环境条件下,森林土壤(山地灰褐土)的保水能力较高,水势消退曲线呈凸形,而牧草地土壤(山地栗钙土)的保水能力相对较弱,水势消退曲线呈凹形。土壤含水量相同时,后者所持水分的有效性更大。

关键词：祁连山水源涵养林土壤水文

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li Hui Ye xue-Zhi Zhang Jian-Xiang Liu hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly