检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

羊膜移植治疗急性眼表烧伤的疗效

国际眼科杂志 2011年第7期11卷 1292-1293页

作者：朱鸿雁中国新疆维吾尔自治区呼图壁县人民医院眼科 831200

目的:讨论羊膜移植术对治疗急性眼表烧伤的疗效。方法:用新鲜的人羊膜移植术来治疗眼部早期烧伤10例12眼。结果:患者12眼均于术后3wk内眼表重新再次上皮化;恢复透明角膜3眼,薄翳5眼,遗留角膜斑翳2眼,角膜白斑者2眼;角膜血管新生3眼,其... 详细信息

目的:讨论羊膜移植术对治疗急性眼表烧伤的疗效。方法:用新鲜的人羊膜移植术来治疗眼部早期烧伤10例12眼。结果:患者12眼均于术后3wk内眼表重新再次上皮化;恢复透明角膜3眼,薄翳5眼,遗留角膜斑翳2眼,角膜白斑者2眼;角膜血管新生3眼,其中限于角膜周边部仅2眼,1眼进入角膜瞳孔区;睑球轻度粘连2眼。结论:羊膜移植治疗早期眼部烧伤可获得稳定的眼表,是一种有效的方法,且为日后行角膜移植术治疗创造了条件。

关键词：羊膜移植术眼表烧伤临床疗效

Therapeutic experience of an 89-year-old high-risk patient with incarcerated cholecystolithiasis:A case report and literature review

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第20期8卷 4908-4916页

作者： Zong-Ming Zhang Chong Zhang zhuo Liu Li-Min Liu Ming-Wen zhu Yue Zhao Bai-Jiang Wan Hai Deng Hai-yan yang Jia-hong Liao hong-yan zhu Xue Wen Li-Li Liu Man Wang Xiao-Ting Ma Miao-MiaoZhang Jiao-Jiao Liu Tian-Tian Liu Niu-Niu Huang Pei-Ying Yuan Yu-Jiao Gao Jing Zhao Xi-Ai Guo FangLiao Feng-Yuan Li Xue-Ting Wang Rui-Jiao Yuan Fang Wu Department of General Surgery Beijing Electric Power HospitalState Grid Corporation of ChinaCapital Medical UniversityBeijing 100073China Department of Pathology Beijing Electric Power HospitalState Grid Corporation of ChinaCapital Medical UniversityBeijing 100073China

BACKGROUND The global pandemic of coronavirus disease 2019 pneumonia poses a particular challenge to the emergency surgical treatment of elderly patients with high-risk acute abdominal *** patients are a high-risk group for surgical *** the incarceration of gallstones cannot be relieved,emergency surgery is *** SUMMARY We report an 89-year-old male patient with acute gangrenous cholecystitis and septic shock induced by incarcerated *** had several coexisting,high-risk underlying diseases,had a history of radical gastrectomy for gastric cancer,and was taking aspirin before the ***,he underwent emergency laparoscopic cholecystectomy,with maintenance of postoperative heart and lung function,successfully recovered,and was discharged on day 8 after the *** Emergency surgery for elderly patients with acute abdominal disease is safe and feasible during the coronavirus disease 2019 pandemic,the key is to abide strictly by the hospital's epidemic prevention regulations,fully implement the epidemic prevention procedure for emergency surgery,fully prepare before the operation,accurately perform the operation,and carefully manage the patient postoperatively.

关键词： Extremely elderly patient Cholecystolithiasis incarceration Acute gangrenous cholecystitis Acute abdominal diseases COVID-19 Case report

Firebird sirolimus eluting stent versus bare mental stent in patients with ST-segment elevation myocardial infarction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2007年第10期120卷 863-867页

作者： GAO Hai yan hong-bing zhu Xiao-ling LI Nan AI Hui WANG Jian LI Shi-ying yanG Duo Emergency Center for Heart Lung and Vessel Diseases Beijing Anzhen Hospital of Capital University of Medical Sciences Beijing 100029 China

Background There are few evidences about the value of drug eluting stent in patients with ST-segment elevation myocardial infarction （STEMI）. We prospectively designed a randomized controlled trial to compare the safety and efficacy of Firebird sirolimus eluting stent （Firebird stent） and bare metal stent （BMS）. Methods Patients with STEMI enrolled during one year period were randomized to undergo implantation of Firebird stent or BMS, and clinical and angiographic follow-up. The primary endpoint of the present study was in-lesion late lumen loss （LLL） at 6 months, and secondary endpoint includes stent thrombosis and major adverse cardiac events （MACE） at 6 months. Results During one year period, 156 patients were randomized into the Firebird stent group （101 patients with an average age of 57.8 years） or the BMS group （55 patients with 59.7 years on average）. Six-month angiographic follow-up was available in 66.3% and 63.7% of patients assigned to Firebird stent and BMS, respectively. At 6-month follow-up, mortality, target vessel revascularization （TVR） and MACE were 2.0%, 6.9% and 9.9% in the Firebird stent group, while 3.6%, 30.9% and 36.4% in the BMS group （P〈0.05）. Subacute thrombosis occurred in 1 patient in both groups, respectively. The mean LLL was 0.18 mm in the Firebird stent group versus 0.72 mm in the BMS group. Conclusion Implantation of Firebird sirolimus eluting stent for STEMI may greatly reduce TVR and MACE at 6 months with low incidence of acute/subacute stent thrombosis compared with BMS.

关键词： myocardial infarction drugs stents

Adrenergic signaling mediates pancreatic hyperalgesia through activation of purinergic receptors in primary sensory neurons in a rat model of chronic pancreatitis

在线全文

学校读者我要写书评

暂无评论

Adrenergic signaling mediates pancreatic hyperalgesia throug...

Eruptive Cutaneous Collagenoma: Report of Two Cases

中国神经科学学会第十届全国学术会议

作者： hong-yan zhu Chun-Hua ZHANG Shu-Fen HU Guang-Yin XU Institute of Neuroscience Key Laboratory of Pain Basic Research and Clinic TherapyDepartment of NeurobiologySoochow University

Objective The neurobiologic basis of pancreatic hyperalgesia in chronic pancreatitis（CP） is poorly understood and there is a great need to identify novel therapeutic *** aim of this study was designed to investigate roles of norepinephrine（NE） and P2X receptor signaling pathways in the pathogenesis of pancreatic pain in a rat model of *** CP was induced in adult rats by intraductal injection of trinitrobenzene sulfonic acid（TNBS）.DiI dye injected into pancreas was used to label pancreas innervating dorsal root ganglion（DRG） neurons.P2X receptor-mediated responses in pancreas-specific DRG neurons were measured using calcium imaging *** blot analysis was performed to examine protein *** hyperalgesia was assessed by nocifensive behavior to mechanical stimulation of rat *** TNBS-injected rats exhibited a robotic pancreatic pain,which was associated with a 2-fold increase in ATP-induced calcium signals when compared with age-matched controls（P＜0.05）.TNBS injection also significantly increased expression of adrenergic β-receptors in thoracic *** administration of P2X receptor antagonist suramine or β receptor antagonist propranolol markedly reduced referred somatic hyperalgesia in rats with ***,these two antagonists failed to produce analgesic effect in healthy control *** addition,incubation of norepinephrine（NE） significantly enhanced ATP-induced calcium signal,which was abolished by propranolol but not by adrenergic a-receptor antagonist *** potentiation of ATP response induced by NE incubation was partially blocked by protein kinase A inhibitor ***,an adenylyl cyclase activator,markedly enhanced ATP-induced responses of pancreas specific DRG *** Sensitization of P2X receptors,which was likely mediated by adrenergic signaling in primary sensory neurons,contributes to pancreatic hyperalgesia,thus identifying a potential target for treating pancreatic

关键词： chronic pancreatitis norepinephrine dorsal root ganglion calcium image purinergic receptors protein kinase A

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

International Journal of Dermatology and Venereology 2021年第2期4卷 128-130页

作者： Jian Wu Mei-hong Cai Ling-Ling Chen Lei Wu Xiao-Jian Chen hong-yan zhu Feng Shi Department of Dermatology and Venereology Suzhou Municipal HospitalSuzhouJiangsu 215008China

Introduction:Eruptive cutaneous collagenoma is non familial connective tissue nevi of unknown etiology presented with an abrupt *** date,the literatures on eruptive cutaneous collagenoma are extremely rare in *** present:Two women presented with multiple asymptomatic,skin-colored papules and nodules on the trunk and extremities with no systemic *** revealed dense,coarse collagen fibers by hematoxylin-esoin stain and decreased,fragmented elastic fibers by Elastic stain compared with the normal *** on these findings,the diagnosis of eruptive cutaneous collagenoma was *** specific treatment was ***:Eruptive cutaneous collagenoma is a very rare dermatosis that is often misdiagnosed as other connective tissue *** pathogenesis is unclear,and also no efficient treatment is *** is usually diagnosed based on clinical and histopathological ***:The present cases are relatively rare type of eruptive cutaneous collagenoma that provide more experience for clinician,and may be helpful for them to make correct diagnosis for suspicious cases.

关键词： case report eruptive cutaneous collagenoma chinese women trunk and extremities

Modulation of voltage-sensitive Na+ currents in differentiated SHSY5Y cells by BmKI

在线全文

学校读者我要写书评

暂无评论

Modulation of voltage-sensitive Na+ currents in differentiat...

表皮生长因子受体及其Ⅲ型突变体在人食管癌的表达及意义

中国神经科学学会第十届全国学术会议

作者： hong-yan zhu Pei XIAO Yu-Xiao ZHAO Nan JIANG Yong-Hua JI Laboratory of Neuropharmacology and Neurotoxicology School of Life SciencesShanghai University

Objective Activation of voltage-gated sodium channels(VGSCs) has been related to disorders of neuronal excitability such as epilepsy and *** I,a site-3-specific modulator of VGSCs from the Chinese scorpion Buthus martensi Karsch,has been confirmed to induce spontaneous nociception and hyperalgesia and generate epileptiform responses in ***,the exact mechanism of modulation of BmK I on VGSCs in never cells is still not yet *** present study is to explore the modulation of BmK I on sodium currents eliciting from differentiated SHSY5Y *** Immunofluorescence revealed that two VGSCs subtypes Navl.2,Navl.6 were expressed with highest abundance in SHSY5Y cells treated with retinoic acid for 6 ***,patch-clamp was performed in SHSY5Y cells treated with retinoic acid for 6 days to record the whole-cell *** The inward currents eliciting from differentiated SHSY5Y cells were totally blocked by 100 nM *** inactivation of I was dramatically delayed in the presence of 500 nM BmK I in SHY5Y cells,and the persistent proportion of I was obviously *** I at500 nM can shift the steady-activation curve toward hyperpolarization direction by 4.8 mV(n=24,P<0.05),additionally,after a series of pulse stimuli the steady-inactivation curve shift toward hyperpolarization direction by ***,BmK I at 500 nM shift the fast inactivation curve toward hyperpolarization direction by 9.1mV(n=15,P<0.05).Conclusion BmK I is an effective and novel molecule in the study of VGSCs-related neuronal hyper-excitability.

关键词： voltage-gated sodium channels electrophysiology α-like scorpion toxin BmK I

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国现代医学杂志 2016年第7期26卷 24-28页

作者：朱彦红韩大正河南大学第一附属医院消化内科河南开封475001

目的检测表皮生长因子受体(EGFR)及表皮生长因子受体Ⅲ型突变体(EGFRvⅢ)在人食管癌组织中的表达,探讨其与食管癌发生、发展的关系及其与各临床病理特征之间的关系。方法采用免疫组织化学染色法(Maxvision TM二步法)检测食管癌组织及正... 详细信息

目的检测表皮生长因子受体(EGFR)及表皮生长因子受体Ⅲ型突变体(EGFRvⅢ)在人食管癌组织中的表达,探讨其与食管癌发生、发展的关系及其与各临床病理特征之间的关系。方法采用免疫组织化学染色法(Maxvision TM二步法)检测食管癌组织及正常食管组织中EGFR和EGFRvⅢ蛋白的表达水平,并将检测结果与临床病理参数进行综合分析。结果食管癌组织EGFR和EGFRvⅢ的表达率分别为65.6%、58.5%,正常食管黏膜EGFR和EGFRvⅢ表达率为30.0%、0%。EGFR在食管癌组织的表达明显高于正常食管组织(P0.05),与食管癌的分化程度、淋巴结转移、远隔器官转移及临床分期相关(P<0.05)。结论EGFR、EGFRvⅢ过度表达可能与食管癌的发生发展密切相关,EGFR、EGFRvⅢ有望作为预测食管癌预后的候选基因,EGFRvⅢ在食管癌组织中特异性表达,可能使其成为食管癌治疗的理想的靶点。

关键词：表皮生长因子受体表皮生长因子受体Ⅲ型突变体食管癌免疫组织化学

A New Smoothing Approach with Diverse Fixed-lags Based on Target Motion Model

在线全文

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2006年第4期3卷 425-430页

作者： Chen Li, Chong-Zhao Han, hong-yan zhu Electronic and Information Engineering, Xi’an Jiaotong University, Xi’an 710049, PRC Electronic and Information Engineering Xi’an Jiaotong University Xi’an PRC

Recently, lots of smoothing techniques have been presented for maneuvering target tracking. Interacting multiple model-probabilistic data association （IMM-PDA） fixed-lag smoothing algorithm provides an efficient solution to track a maneuvering target in a cluttered environment. Whereas, the smoothing lag of each model in a model set is a fixed constant in traditional algorithms. A new approach is developed in this paper. Although this method is still based on IMM-PDA approach to a state augmented system, it adopts different smoothing lag according to diverse degrees of complexity of each model. As a result, the application is more flexible and the computational load is reduced greatly. Some simulations were conducted to track a highly maneuvering target in a cluttered environment using two sensors. The results illustrate the superiority of the proposed algorithm over comparative schemes, both in accuracy of track estimation and the computational load.

关键词： Maneuvering target tracking smoothing lag interacting multiple model (IMM) probabilistic data association(PDA)

在线全文

学校读者我要写书评

暂无评论

舌诊在不孕症诊治中的运用体会

中华中医药杂志 2017年第4期32卷 1630-1632页

作者：朱红梅赖鹏华洪燕珠厦门大学医学院中医系厦门361102

不孕症为临床常见病症,然临床常见因无明显症状或症状过多而不好辨证。舌诊在四诊中受外界影响较小,舌质可验病之阴阳虚实,舌苔可辨邪之寒热,笔者在临床通过辨识舌象遣方用药治疗不孕症,每能切中要害,文章就临床不孕症常见舌象和用药经... 详细信息

不孕症为临床常见病症,然临床常见因无明显症状或症状过多而不好辨证。舌诊在四诊中受外界影响较小,舌质可验病之阴阳虚实,舌苔可辨邪之寒热,笔者在临床通过辨识舌象遣方用药治疗不孕症,每能切中要害,文章就临床不孕症常见舌象和用药经验做一总结。

关键词：不孕症舌诊经验