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Analysis of therapeutic effect of cell reduction combined with intraperitoneal thermoperfusion chemotherapy in treatment of peritoneal pseudomyxoma

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World Journal of Gastrointestinal Surgery 2024年第11期16卷 3520-3530页

作者： Wei-Wei Li Xiu-Mei Ru hong-yan xuan Qi Fan Jing-Jing Zhang Jun Lu Department of Endocrinology The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina Department of Anus and Intestine Surgery Xiangya Hospital of Central South UniversityChangsha 410008Hunan ProvinceChina

BACKGROUND Pseudomyxoma peritonei is a rare tumor that can produce a biological behavior similar to that of a malignant *** resection combined with chemo-therapy is the traditional treatment method,but the effect is not *** reduction(CRS)combined with intraperitoneal thermoperfusion chemotherapy(HIPEC)has become a new method for the treatment of peritoneal pseudomy-xoma(PMP).AIM To find out if CRS and HIPEC can be used safely and effectively to treat *** This is an observational *** data of PMP patients treated with CRS+HIPEC at our hospital from January 2013 to June 2023 was collated and *** main outcome measures were overall survival(OS),and the secondary outcome measures were the incidence of surgical complications and serious adverse *** were graded according to common adverse event evaluation *** tumor staging was performed using the peritoneal tumor index(PCI)scoring system,and a cell reduction degree(CCR)score was performed after ***-0 and CCR-1 were considered satisfactory *** A total of 186 patients with PMP were included,with a median age of 56(48-64)years,65(34.9%)years in males,and 121(65.1%)years in *** median PCI score was 28(20-34)*** median operative time was 300(211-430)minutes,and no significant complications occurred.91.4%(170/186)were from the appendix,53.2%(99/186)were from the low grade,and 30.6%(57/186)were from the high *** scores showed that 55 patients(29.6%)achieved satisfactory CRS,and 113 patients(60.8%)did not achieve satisfactory *** fatality rate at 30 days after surgery was 2.7%(5/186),1.6%(3/186)needed a second operation,and the fatality rate at 90 days was 4.3%(8/186).The total incidence of III-IV complications was 43.0%(80/186),among which the higher incidence was mainly anemia(27.4%,51/186),electrolyte disturbance(11.6%,21/181),and albumin decrease(7.5%,14/186).The main compli-cations associated with abdominal surger

关键词： Peritoneal pseudomyxoma Cell reduction Intraperitoneal thermoperfusion chemotherapy Survival prognosis Observational study

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Construction of Genetic Linkage Map Based on SSR Markers in Peanut(Arachis hypogaea L.)

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Agricultural Sciences in China 2008年第8期7卷 915-921页

作者： hong yan-bin LIANG xuan-qiang CHEN Xiao-ping LIU Hai-yan ZHOU Gui-yuan LI Shao-xiong WEN Shi-jie Crops Research Institute Guangdong Academy of Agricultural Sciences Guangzhou 510640 P.R.China

Molecular genetic maps of crop species can be used in a variety of ways in breeding and genomic research such as identification and mapping of genes and quantitative trait loci （QTLs） for morphological, physiological and economic traits of crop species. However, a comprehensive genetic linkage map for cultivated peanut has not yet been developed due to the extremely low frequency of DNA polymorphism in cultivated peanut. In this study, 142 recombinant inbred lines （RILs） derived from a cross between Yueyou 13 and Zhenzhuhei were used as mapping population in peanut （Arachis hypogaea L.）. A total 652 pairs of genomic-SSR primer and 392 pairs of EST-SSR primer were used to detect the polymorphisms between the two parents. 141 SSR primer pairs, 127 genomic-SSR and 14 EST-SSR ones, which can be used to detect polymorphisms between the two parents, were selected to analyze the RILs population. Thus, a linkage genetic map which consists of 131 SSR loci in 20 linkage groups, with a coverage of 679 cM and an average of 6.12 cM of inter-maker distance was constructed. The putative functions of 12 EST-SSR markers located on the map were analyzed. Eleven showed homology to gene sequences deposited in GenBank. This is the first report of construction of a comprehensive genetic map with SSR markers in peanut （Arachis hypogaea L.）. The map presented here will provide a genetic framework for mapping the qualitative and quantitative trait in peanut.

关键词： peanut (Arachis hypogaea L.) SSR genetic linkage map

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Foliar-applied zinc promotes cadmium allocation from leaf surfaces to grains in rice

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Journal of Environmental Sciences 2025年第5期151卷 582-593页

作者： Ya-Ting Liu Bo-Fang yan xuan Cai hong-Xiang Zheng Rong-Liang Qiu Ye-Tao Tang School of Environmental Science and Engineering Sun Yat-sen UniversityGuangzhou 510006China Institute of Facility Agriculture Guangdong Academy of Agricultural SciencesGuangzhou 510640China Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology Sun Yat-sen UniversityGuangzhou 510006China Guangdong Provincial Key Laboratory of Agricultural&Rural Pollution Abatement and Environmental Safety College of Natural Resources and EnvironmentSouth China Agricultural UniversityGuangzhou 510642China

The accumulation of Cd by rice poses significant health *** fertilizationwith Zn can reduce grain Cd contents in rice grown in Cd-contaminated ***,atmospheric deposition on leaves is another vector of Cd contamination,and it remains unclear how Zn application affects the allocation of such *** conducted an experiment where the flag leaves of rice plants were treated with solutions with various Zn concentrations and a constant Cd *** 111Cd stable isotope was used to trace the flux of foliarapplied *** levels of foliar-applied Zn enhanced Cd efflux and grain *** is attributed to limited sequestration of foliar-applied Cd in the leaf cell symplasm and increased Cd desorption from leaf cell walls when a high Zn^(2+)concentration occurs in the *** Zn oxide nanoparticlesmitigated these ***,the expressions of OsLCT1 and OsZIP7 in flag leaves and OsHMA2 and OsZIP7 in the uppermost nodes were upregulated under high-Zn^(2+)treatment,which may facilitate Cd phloem loading and grain *** is advised in using foliar Zn in areas with high atmospheric Cd due to potential grain-contamination risks.

关键词： Atmospheric deposition Isotope labelling Metal interaction Phloem Cell wall

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An Efficient and Flexible Bifunctional Dual-Band Electrochromic Device Integrating with Energy Storage

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Nano-Micro Letters 2025年第4期17卷 419-434页

作者： Zekun Huang Yutao Peng Jing Zhao Shengliang Zhang Penglu Qi Xianlin Qu Fuqiang yan Bing Ding Yimin xuan Xiaogang Zhang Jiangsu Key Laboratory of Electrochemical Energy Storage Technologies College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China Key Laboratory of Thermal Management and Energy Utilization of Aviation Vehicles College of Energy and Power EngineeringNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China Center for Microscopy and Analysis Nanjing University of Aeronautics and AstronauticsNanjing 211106People’s Republic of China

Dual-band electrochromic devices capable of the spectral-selective modulation of visible(VIS)light and near-infrared(NIR)can notably reduce the energy consumption of buildings and improve the occupants’visual and thermal ***,the low optical modulation and poor durability of these devices severely limit its practical ***,we demonstrate an efficient and flexible bifunctional dual-band electrochromic device which not only shows excellent spectral-selective electrochromic performance with a high optical modulation and a long cycle life,but also displays a high capacitance and a high energy recycling efficiency of 51.4%,integrating energy-saving with *** nanowires structure and abundant oxygen-vacancies of oxygen-deficient tungsten oxide nanowires endows it high flexibility and a high optical modulation of 73.1%and 85.3%at 633 and 1200 nm *** prototype device assembled can modulate the VIS light and NIR independently and effectively through three distinct modes with a long cycle life(3.3%capacity loss after 10,000 cycles)and a high energy-saving performance(8.8℃lower than the common glass).Furthermore,simulations also demonstrate that our device outperforms the commercial low-emissivity glass in terms of energy-saving in most climatic zones around the *** windows represent an intriguing potential technology to improve the building energy efficiency.

关键词： Electrochromic Dual-band electrochromic devices Spectral-selective modulation Flexible Energy storage

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A novel method for simultaneous measurement of^(222)Rn and^(220)Rn progeny concentrations measured by an alpha spectrometer

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Nuclear Science and Techniques 2025年第1期36卷 127-139页

作者： Zhong-Kai Fan Jia-Le Sun Hao-xuan Li Xiang-Ming Cai Hui yang Shou-Kang Qiu yan-Liang Tan Jian Shan School of Nuclear Science and Technology University of South ChinaHengyang 421001China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421008China

The accumulation of^(222)Rn and^(220)Rn progeny in poorly ventilated environments poses the risk of natural radiation exposure to the public.A previous study indicated that satisfactory results in determining the^(222)Rn and^(220)Rn progeny concentrations by measuring the total alpha counts at five time intervals within 560 min should be expected only in the case of high progeny concentrations in *** complete the measurement within a relatively short period and adapt it for simultaneous measurements at comparatively lower^(222)Rn and^(220)Rn progeny concentrations,a novel mathematical model was proposed based on the radioactive decay *** model employs a nonlinear fitting method to distinguish nuclides with overlapping spectra by utilizing the alpha particle counts of non-overlapping spectra within consecutive measurement cycles to obtain the concentrations of^(222)Rn and^(220)Rn progeny in *** verification experiments were conducted using an alpha *** experimental results demonstrate that the concentrations of^(222)Rn and^(220)Rn progeny calculated by the new method align more closely with the actual circumstances than those calculated by the total count method,and their relative uncertainties are all within±16%.Furthermore,the measurement time was reduced to 90 min,representing an acceleration of 84%.The improved capability of the new method in distinguishing alpha particles with similar energies emitted from ^(218)Po and^(212)Bi,both approximately 6 MeV,contributed to realizing more accurate *** proposed method has the potential advantage of measuring relatively low concentrations of^(222)Rn and^(220)Rn progeny in air more quickly via air filtration.

关键词： ^(222)Rn ^(220)Rn Progeny concentration Nonlinear fitting method Alpha spectrometer

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Performance and electromagnetic mechanism of radar-and infraredcompatible stealth materials based on photonic crystals

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International Journal of Minerals,Metallurgy and Materials 2025年第3期32卷 710-717页

作者： yanming Liu xuan yang Lixin xuan Weiwei Men Xiao Wu Yuping Duan AVIC Research Institute for Special Structures of Aeronautical Composite Ji’nan 250023China Aviation Key Lab of Science and Technology on High Performance Electromagnetic Windows Ji’nan 250023China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116085China

Traditional stealth materials do not fulfill the requirements of high absorption for radar waves and low emissivity for infrared ***,they can be detected by various technologies,considerably threatening weapon ***,a stealth material compatible with radar and infrared was designed based on the photonic bandgap characteristics of photonic *** radar stealth lay-er(bottom layer)is a composite of carbonyl iron/silicon dioxide/epoxy resin,and the infrared stealth layer(top layer)is a 1D photonic crystal with alternately and periodically stacked germanium and silicon *** composition optimization and structural adjust-ment,the effective absorption bandwidth of the compatible stealth material with a reflection loss of less than-10 dB has reached 4.95 *** average infrared emissivity of the proposed design is 0.1063,indicating good stealth *** theoretical analysis proves that photonic crystals with this structural design can produce infrared waves within the photonic bandgap,achieving high radar wave transmittance and low infrared *** stealth is achieved without affecting the absorption performance of the radar stealth layer,and the conflict between radar and infrared stealth performance is *** work aims to promote the application of photonic crystals in compatible stealth materials and the development of stealth technology and to provide a design and theoretical found-ation for related experiments and research.

关键词： microwave absorption infrared stealth photonic crystal compatible stealth

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Anti-programmed death-1 immunotherapy-promising treatment for metastatic colorectal cancer:A case report

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World Journal of Gastrointestinal Oncology 2025年第2期17卷 291-298页

作者： Tian-Hao Guo Sheng-Wei hong Wen-Jian Zhu Yi-Fan Hui Wen-Li Qiu yan Wu xuan Li Fei Ke Liu Li Hai-Bo Cheng Institute of Health and Regimen Jiangsu Open UniversityNanjing 210036Jiangsu ProvinceChina The First Clinical Medical College Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Radiology Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Oncology Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Pathology Jiangsu Provincial Hospital of Traditional Chinese Medicine(Affiliated Hospital of Nanjing University of Chinese Medicine)Nanjing 210029Jiangsu ProvinceChina

BACKGROUND Colorectal cancer(CRC)is the third most prevalent form of cancer *** patients with CRC,colorectal liver metastasis(CRLM)is the foremost direct contributor to *** recent years,immunotherapy has swiftly risen to prominence as a vital approach for treating a range of solid tumors,including *** present a unique case of a patient suffering from CRLM,with the goal of offering an insightful example and relevant references for the treatment of *** SUMMARY We report a patient who experienced liver metastasis after undergoing successful surgical removal of CRC,with the postoperative pathological stage identified as *** patient has been receiving a combination treatment of Western and Traditional Chinese *** assessments of the patient’s condition have been conducted,encompassing evaluations of serum carcinoembryonic antigen levels,carbohydrate antigen 199,and observations of the tongue complexion and its *** patient achieved clinical remission after anti-programmed death-1 immunotherapy when various systemic therapies *** the diagnosis of CRLM,the patient has survived for more than 6 years,surpassing the expected survival time for those with advanced *** This case illustrates the considerable promise of anti-programmed death-1 immunotherapy in managing CRLM,especially in scenarios of drug resistance and disease progression.

关键词： Colorectal cancer Colorectal liver metastasis Drug resistance Immunotherapy Anti-programmed death-1 Case report

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Synthesis of ternary geopolymers using prediction for effective solidification of mercury in tailings

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Journal of Environmental Sciences 2025年第1期147卷 392-403页

作者： xuan Lu Jinfa Guo Fang Chen Mengkui Tian School of Chemistry and Chemical Engineering Guizhou UniversityGuiyang 550025China

This study used steel slag,fly ash,and metakaolin as raw materials(SFM materials)to create silica-alumina-based geopolymers that can solidify Hg^(2+)when activated with sodiumbased water *** experiments began with a triangular lattice point mixing design experiment,and the results were fitted,analyzed,and *** optimum SFM material mass ratio was found to be 70%steel slag,25%fly ash,and 5%*** optimum modulus of the activator was identified by comparing the unconfined compressive strength and solidifying impact on Hg^(2+)of geosynthetics with different *** SFM geopolymer was then applied in the form of potting to cure the granulated mercury *** inclusion of 50%SFM material generated a geosynthetic that reduced mercury transport to the surface soil by roughly 90%.The mercury concentration of herbaceous plant samples was also reduced by 78%.It indicates that the SFM material can effectively attenuate the migration transformation of ***,characterization methods such as XPS and FTIR were used to investigate the mechanism of Hg^(2+)solidification by geopolymers generated by SFM *** possible solidification mechanisms were proposed as alkaline environment-induced mercury precipitation,chemical bonding s,surface adsorption of Hg^(2+)and its precipitates by the geopolymer,and physical encapsulation.

关键词： Mercury Geopolymer Solidification Tailings

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Three-dimensional fracture of UO_(2)ceramic pellets by phase field modeling

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 165-176页

作者： Wei Xiong xuan Ye hongzhang Cheng Xiaoming Liu Institute of Nuclear and New Energy Technology Collaborative Innovation Center of Advanced Nuclear Energy TechnologyKey Laboratory of Advanced Reactor Engineering and Safety of Ministry of EducationTsinghua UniversityBeijing 100084China State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Fracture is the primary failure type for the UO_(2)ceramic pellets,which are operated under irradiation and thermal processes,and physically confined by the *** this work,by combining closely coupled physical processes of heat conduction,heat transfer,and mechanical deformation with the cohesive phase field framework,we proposed a high-precision modeling of quasistatic cracking of three-dimensional(3D)UO_(2)ceramic fuel pellets under high temperature and *** simulation results agree well with the experimental results,indicating that the proposed method has the potential to capture 3D crack modes in the interested time ***,we studied the relation of the 3D fracture patterns of fuel pellets with the peak power *** was found that the power level plays a critical role in determining the competition between radial and circumferential cracks,as well as transverse penetrating cracks.

关键词： phase field method nuclear fuel pellet coupled thermo-mechanical model thermal fracture

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Emerging progress:photochemical transformation of nitroso compounds

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Science China Chemistry 2025年第1期68卷 118-133页

作者： Ze-Le Chen Qiang-Qiang Li Armido Studer Jun xuan Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials School of Chemistry&Chemical EngineeringAnhui UniversityHefei 230601China Organisch-Chemisches Institut Universitat MünsterMunster 48149Germany

Nitroso compounds have emerged as highly valuable reaction partners or reagents in organic synthesis due to their rich *** versatile profile of these compounds allows them to function as electrophiles,nucleophiles,diradicals,and radical acceptors in diverse *** recent years,notable progress has been made in harnessing photochemical reactions with nitroso compounds to prepare N,O-containing structures using mild and eco-friendly *** nitroso compounds like nitrosoarenes,acyloxy nitroso compounds,N-nitrosoamines and nitrites have received significant attention for their ability to introduce NO moieties into complex molecules that are otherwise difficult to *** this review,we provide an overview of the recent advancements in the visible light-induced conversion of nitroso compounds,with particular emphasis on their role as bifunctional reagents and acceptors of radicals,carbenes and nitrenes.

关键词： nitroso compounds photochemistry radical reaction carbene transformation nitrosoarenes

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