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Theoretical calculations of hyperfine splitting,Zeeman shifts,and isotope shifts of^(27)Al^(+)and logical ions in Al^(+)clocks

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Chinese Physics B 2021年第12期30卷 361-369页

作者： Xiao-Kang Tang Xiang Zhang Yong Shen hong-xin zou College of Liberal Arts and Sciences National University of Defense TechnologyChangsha 410073China

Based on the multiconfiguration Dirac-Hartree-Fock(MCDHF)method,similar models are employed to simultaneously calculate the first-order and second-order Zeeman coefficients as well as the hyperfine interaction constants of the related energy levels of ^(27)Al^(+)and its logical ions ^(9)Be^(+)and^(25)Mg^(+)in the^(27)Al^(+)optical *** less than 0.34%deviations from experimental values in Zeeman coefficients of^(27)Al^(+),these calculated parameters will be of great help for better evaluation of the systematic *** also calculate the isotope shift parameters of the related energy levels,which could extend our knowledge and understanding of nuclear properties of these ions.

关键词： Zeeman effect isotope shift aluminum ion optical clock MCDHF method

Parameters of Isotope Shifts for 2s2p3,1P1→ 2s2 1S0 Transitions in Heavy Be-Like Ions

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Chinese Physics Letters 2019年第11期36卷 14-17页

作者： Xiang Zhang Jian-Peng Liu Ji-Guang Li hong-xin zou College of Liberal Arts and Science National University of Defense TechnologyChangsha 410073 Institute of Applied Physics and Computational Mathematics Beijing 100088

The field shift and mass shift parameters of the 2s2p3,1P1→ 2s2 1S0 transitions in Be-like ions(70 ≤ Z≤ 92)are calculated using the multi-configuration Dirac–Hartree–Fock and the relativistic configuration interaction methods with the inclusion of the Breit interaction and the leading QED corrections. We find that the mass shift parameters of these two transitions do not change monotonously along the isoelectronic sequence in the high-Z range due to the relativistic nuclear recoil effects. A minimum value exists for the specific mass shift parameters around Z= 80, especially for the 2s2p3,1P1→ 2s2 1S0 transition. In addition, the field shifts and mass shifts of these two transitions are estimated using an empirical formula, and their contributions are compared along the isoelectronic sequence.

关键词： transition. transitions relativistic

Forbidden transition properties of fine-structure 2p^3 ~4S_(3/2)–2p^3 ~2D_(3/2,5/2) for nitrogen-like ions

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Chinese Physics B 2018年第8期27卷 196-203页

作者： Xiao-Kang He Jian-Peng Liu Xiang Zhang Yong Shen hong-xin zou College of Liberal Arts and Sciences National University of Defense TechnologyChangsha 410073China

Based on relativistic wave functions from multiconfiguration Dirac-Hartree-Fock and configuration interaction cal- culations, E2 and M1 transition probabilities of 2p3 4S3/2-2p3 2D3/2,5/2 are investigated in the nitrogen-like sequence with 7 〈 Z 〈 16. The contributions of the electron correlations, Breit interaction, and the quantum electrodynamic （QED） effects on the transition properties are analyzed. The present results can be used for diagnosing plasma. In addition, several N-like ions can also be recommended as a promising candidate for a highly charged ion （HCI） clock with a quality factor （Q） of trnnsition as hitch as 1020.

关键词： forbidden transition probabilities nitrogen-like ions MCDHF method RCI

Current status of drug therapy for chronic hepatitis B

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World Journal of Gastroenterology 2025年第2期31卷 1-12页

作者： Chuang Jiang Zhi-hong Zhang Jia-xin Li Division of Liver Surgery Department of General Surgery and Laboratory of Liver Surgeryand State Key Laboratory of Biotherapy and Collaborative Innovation Center of BiotherapyWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of General Surgery Dafang County People's HospitalBijie 551600Guizhou ProvinceChina

In this editorial,we comment on the article by Meng et *** hepatitis B(CHB)is a significant global health problem,particularly in developing *** B virus(HBV)infection is one of the most important risk factors for cirrhosis and hepatocellular *** and treatment of HBV are key measures to reduce *** present,drug therapy can effectively control virus replication and slow disease progression,but completely eliminating the virus remains a ***-HBV treatment is a long-term process,and there are many kinds of antiviral drugs with different mechanisms of action,it is essential to evaluate the safety and efficacy of these drugs to reduce side effects and improve patients’*** will summarize the current status of CHB drug treatment,hoping to provide a reference for the selection of clinical antiviral drugs.

关键词： Chronic hepatitis B Hepatitis B virus Anti virus Drug treatment Therapy

稀土对TiC基金属陶瓷耐磨堆焊材料组织性能的影响

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中国稀土学报 2001年第3期19卷 232-237页

作者：王新洪邹增大山东大学材料学院济南250061

应用扫描电镜、透射电镜等测试手段和冲击试验、磨损试验 ,研究了TiC基金属陶瓷堆焊材料中加入稀土氧化物 ,对堆焊材料的组织、界面相结构、显微硬度、冲击韧性和磨损性能的影响 ,初步探讨了稀土氧化物改善界面显微结构、提高胎体金属... 详细信息

应用扫描电镜、透射电镜等测试手段和冲击试验、磨损试验 ,研究了TiC基金属陶瓷堆焊材料中加入稀土氧化物 ,对堆焊材料的组织、界面相结构、显微硬度、冲击韧性和磨损性能的影响 ,初步探讨了稀土氧化物改善界面显微结构、提高胎体金属韧性的作用机制。研究结果表明 ,稀土氧化物能细化堆焊层胎体金属组织 ,消除胎体金属的缺陷 ,细化胎体金属断口韧窝并使撕裂棱数量增加 ,提高堆焊层冲击韧性和塑性 ,促使金属基陶瓷与胎体金属界面形成多晶过渡区和局部非晶态物相 ,提高界面的结合强度。稀土氧化物的加入对胎体金属显微硬度的影响不大 ,但能显著提高堆焊层干摩擦磨损状态下的耐磨性。

关键词：稀土氧化物 TiC基金属陶瓷组织结构力学性能耐磨性碳化钛陶瓷堆焊材料

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纳米胶体金的制备及其抗体标记研究

食品科技 2011年第3期36卷 249-252页

作者：宋宏新邹联柱李韵李红心陕西科技大学生命科学与工程学院西安710021

研究通过光谱扫描,确定了柠檬酸钠还原法制备纳米胶体金的最佳条件:100mL0.01%四氯金酸溶液中添加1%柠檬酸钠2mL,反应10min,制备的胶体金粒径为15～20nm,并将其与抗牛β-酪蛋白IgG连接制得了胶体金标记抗体,通过考马斯亮蓝法测得蛋白标... 详细信息

研究通过光谱扫描,确定了柠檬酸钠还原法制备纳米胶体金的最佳条件:100mL0.01%四氯金酸溶液中添加1%柠檬酸钠2mL,反应10min,制备的胶体金粒径为15～20nm,并将其与抗牛β-酪蛋白IgG连接制得了胶体金标记抗体,通过考马斯亮蓝法测得蛋白标记率为74.5%,采用间接ELISA方法测得金标抗体的效价在1∶4000以上,抗体金标后活性良好,可以满足免疫检测的需要。

关键词：胶体金柠檬酸钠还原法 β-酪蛋白金标抗体

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： xin Zhou Dan Ma Yi-Xiang He Jing Jin hong-Lian Wang Yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

Multi-Stage-Based Siamese Neural Network for Seal Image Recognition

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 405-423页

作者： Jianfeng Lu Xiangye Huang Caijin Li Renlin xin Shanqing Zhang Mahmoud Emam School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China Shangyu Institute of Science and Engineering Hangzhou Dianzi UniversityShaoxing312300China Faculty of Artificial Intelligence Menoufia UniversityShebin El-Koom32511Egypt

Seal authentication is an important task for verifying the authenticity of stamped seals used in various domains to protect legal documents from tampering and *** seal inspection is commonly audited manually to ensure document ***,manual assessment of seal images is tedious and laborintensive due to human errors,inconsistent placement,and completeness of the *** image recognition systems are inadequate enough to identify seal types accurately,necessitating a neural network-based method for seal image ***,neural network-based classification algorithms,such as Residual Networks(ResNet)andVisualGeometryGroup with 16 layers(VGG16)yield suboptimal recognition rates on stamp ***,the fixed training data categories make handling new categories to be a challenging *** paper proposes amulti-stage seal recognition algorithmbased on Siamese network to overcome these ***,the seal image is pre-processed by applying an image rotation correction module based on Histogram of Oriented Gradients(HOG).Secondly,the similarity between input seal image pairs is measured by utilizing a similarity comparison module based on the Siamese ***,we compare the results with the pre-stored standard seal template images in the database to obtain the seal *** evaluate the performance of the proposed method,we further create a new seal image dataset that contains two subsets with 210,000 valid labeled pairs in *** proposed work has a practical significance in industries where automatic seal authentication is essential as in legal,financial,and governmental sectors,where automatic seal recognition can enhance document security and streamline validation ***,the experimental results show that the proposed multi-stage method for seal image recognition outperforms state-of-the-art methods on the two established datasets.

关键词： Seal recognition seal authentication document tampering siamese network spatial transformer network similarity comparison network

Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao Qin Dong Dan zou Zhijun Yang Lili Guo Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation