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Retrieval of a Disconnected Left Atrial Appendage Occluder with Endoscopic Grasping Forceps

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Chinese Medical Journal 2018年第3期131卷 368-369页

作者： Lu Yu ru-hong jiang Yi-Qi ruan Chen-Yang jiang Department of Cardiology Sir Run Run Shaw Hospital Zhejiang University Hangzhou Zhejiang 310016 China

Left atrial appendage occlusion （LAAO） has been widely accepted as an alternative to oral anticoagulation for stroke prevention in patients with nonvalvular atrial fibrillation （AF）.However,the periprocedural complications such as device embolization are still challenging. Here,we reported a rare case of an AMPLATZERTM Cardiac Plug （ACP;*** Medical,USA） device disconnection with the delivery cable during the LAAO procedure.

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Non-pulmonary vein foci induced before and after pulmonary vein isolation in patients undergoing ablation therapy for paroxysmal atrial fibrillation: incidence and clinical outcome

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2014年第10期15卷 915-922页

作者： Hui CHENG Yin-yin DAI ru-hong jiang Qiang LIU Ya-xun SUN Jian-wei LIN Zu-wen ZHANG Shi-quan CHEN Jun ZHU Xia SHENG Chen-yang jiang Department of Cardiology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Department of Cardiology the First People's Hospital of Xiaoshan

Objective： To evaluate the incidence and clinical outcome of adenosine triphosphate（ATP） plus isoproterenol（ISP）-induced non-pulmonary vein（PV） foci before and after circumferential PV isolation（CPVI） during index ablation in patients with paroxysmal atrial fibrillation（PAF）. Methods： In 80 consecutive patients undergoing catheter ablation for drug-refractory, symptomatic PAF at our hospital from April 2010 to January 2011, atrial fibrillation（AF） was provoked with ATP（20 mg） and ISP（20 μg/min） administration before and after CPVI. The spontaneous initiation of AF was mapped and recorded. Results： Before ablation, AF mostly originating from PVs（PV vs. non-PV, 36/70 vs. 3/70; P〈0.01） was induced in 39 patients with sinus rhythm. CPVI significantly suppressed AF inducibility; however, more non-PV foci were provoked（post-CPVI vs. pre-CPVI, 13/76 vs. 3/70; P=0.016）. Patients with pre- and post-CPVI induced AF（n=49） were divided according to non-PV foci being induced（group N, n=17） or not（group P, n=32）. After mean（19.2±8.2） months follow-up, 88.2%（15/17） and 65.6%（21/32） of patients in groups N and P, respectively, were free from AF recurrence（P=0.088）. Conclusions： ATP＋ISP administration effectively provokes non-PV foci, especially after CPVI in PAF patients. Although in this study difference did not achieve statistical significance, supplementary ablation targeting non-PV foci might benefit clinical outcome.

关键词： Atrial fibrillation Non-pulmonary vein foci Adenosine triphosphate

基于InP@ZnS QDs/Dured纳米荧光探针的DNA检测

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发光学报 2017年第3期38卷 288-295页

作者：胡先运孟铁宏张汝国江家志黄星宏东南大学生物科学与医学工程学院生物电子学国家重点实验室江苏南京210096 黔南民族医学高等专科学校贵州都匀558000

利用巯基丙酸包覆的In P@Zn S量子点(QDs)与Dured构建了一种检测DNA的荧光探针。在该探针中,以环境友好型带负电的In P@Zn S量子点为荧光团,与带正电的Dured通过静电结合,构建了In P@Zn S QDs/Dured纳米荧光探针。通过荧光共振能量转移(... 详细信息

利用巯基丙酸包覆的In P@Zn S量子点(QDs)与Dured构建了一种检测DNA的荧光探针。在该探针中,以环境友好型带负电的In P@Zn S量子点为荧光团,与带正电的Dured通过静电结合,构建了In P@Zn S QDs/Dured纳米荧光探针。通过荧光共振能量转移(FRET)机理,量子点荧光被猝灭;当DNA存在时,Dured与DNA的特异性结合使Dured从In P@Zn S QDs表面脱附,FRET过程被打断,In P@Zn S QDs荧光恢复,以荧光"关-开"方式检测DNA。该探针检测DNA的线性范围为2.0~275.0 ng·L-1,检测限为1.0 ng·L-1,并可用于模拟生物生理条件下的DNA检测。

关键词： InP@zns量子点荧光探针 DNA 荧光共振能量转移

Metabolic benefits of rivaroxaban in non-valvular atrial fibrillation patients after radiofrequency catheter ablation

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第11期18卷 946-954页

作者： Jun ZHU Rong-jun GAO Qiang LIU ru-hong jiang Lu YU Ya-xun SUN Pei ZHANG Jian-wei LIN Yang YE Zu-wen ZHANG Shi-quan CHEN Hui CHENG Xia SHENG Chen-yang jiang Department of Cardiology Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China Traditional Chinese Medicine Hospital of Wuhu Anhui 241000China

Background and objective： Rivaroxaban is a new oral anticoagulant for stroke prevention in patients with non-valvular atrial fibrillation （NVAF）, which has less drug-food interaction than warfarin. We conducted this pro- spective randomized study to evaluate the metabolic benefits as well as the safety and efficacy with rivaroxaban versus warfarin in patients with NVAF following radiofrequency catheter ablation （RFCA）. Methods： From April to July 2014, 60 patients with NVAF undergoing RFCA were prospectively enrolled in our study. Following RFCA, all patients were randomly assigned to receive rivaroxaban （Group R, n=30） or warfarin （Group W, n=30）. Metabolic indices including serum total protein, albumin, globulin, and high-density lipoprotein （HDL） as well as bleeding, stroke, and systemic thromboembolism events were evaluated and compared during follow-up after 15, 30, 60, and 90 d of RFCA procedure. Results： Serum total protein, albumin, globulin, and HDL levels were all significantly elevated at each follow-up stage in Group R when compared to the baseline （P〈0.05 respectively）. In Group W, the metabolic indices decreased at first and then had an increasing trend. There were no deaths or thromboembolic complications in each group. The prevalence of total bleeding complications was similar between Group R and Group W （11/30, 36.7% vs. 10/30, 33.3%, P=0.70）. Conclusions： Patients with NVAF receiving rivaroxaban after RFCA procedures appear to benefit from a metabolic perspective compared with warfarin, providing practical clinical reference for the choice of the anticoagulant. Rivaroxaban seems to be as safe and effective in preventing thromboembolic events as warfarin for these patients.

关键词： Atrial fibrillation Radiofrequency catheter ablation Anticoagulation Rivaroxaban

Current status of drug therapy for chronic hepatitis B

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World Journal of Gastroenterology 2025年第2期31卷 1-12页

作者： Chuang jiang Zhi-hong Zhang Jia-Xin Li Division of Liver Surgery Department of General Surgery and Laboratory of Liver Surgeryand State Key Laboratory of Biotherapy and Collaborative Innovation Center of BiotherapyWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of General Surgery Dafang County People's HospitalBijie 551600Guizhou ProvinceChina

In this editorial,we comment on the article by Meng et *** hepatitis B(CHB)is a significant global health problem,particularly in developing *** B virus(HBV)infection is one of the most important risk factors for cirrhosis and hepatocellular *** and treatment of HBV are key measures to reduce *** present,drug therapy can effectively control virus replication and slow disease progression,but completely eliminating the virus remains a ***-HBV treatment is a long-term process,and there are many kinds of antiviral drugs with different mechanisms of action,it is essential to evaluate the safety and efficacy of these drugs to reduce side effects and improve patients’*** will summarize the current status of CHB drug treatment,hoping to provide a reference for the selection of clinical antiviral drugs.

关键词： Chronic hepatitis B Hepatitis B virus Anti virus Drug treatment Therapy

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论对大学生进行先进文化教育的主要内容

合肥工业大学学报（社会科学版） 2006年第5期20卷 74-79页

作者：洪江如安徽理工大学人事处安徽淮南232001

什么是中国的先进文化,如何对当代大学生进行先进文化的教育,是一个非常重要的问题。文章提出了对大学生进行先进文化教育的主要内容,包括理想信念、爱国主义、道德素质、时代精神、人文和科学素质、传统文化和外来文化教育等方面。

关键词：大学生先进文化主要内容

新形势下必须坚定的守纪律和讲规矩——深入学习习近平总书记关于严明党的纪律和规矩的重要论述

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安徽理工大学学报（社会科学版） 2017年第5期19卷 19-24页

作者：洪江如安徽理工大学纪委安徽淮南232001

严明的纪律和规矩是马克思主义政党与生俱来的内在品质,是区别于其他政党的重要标志,是思想建党、组织建党的重要基础。我们党历来高度重视党的政治纪律和政治规矩。从建党到建国,再到社会主义建设和改革开放,全党同志牢记使命,恪守党... 详细信息

严明的纪律和规矩是马克思主义政党与生俱来的内在品质,是区别于其他政党的重要标志,是思想建党、组织建党的重要基础。我们党历来高度重视党的政治纪律和政治规矩。从建党到建国,再到社会主义建设和改革开放,全党同志牢记使命,恪守党的纪律,战胜了一个又一个艰难险阻,不断从胜利走向新的胜利。新形势下,面对"四种危险"和"四大考验",我们必须牢固树立坚定的理想信念,守纪律讲规矩意识,"纪"严于"法"的思维,全面纪律审查的思维等。

关键词：守纪律讲规矩理想信念

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论高校工会在构建和谐校园中的作用

安徽农业大学学报（社会科学版） 2008年第1期17卷 44-48页

作者：洪江如安徽理工大学工会安徽淮南232001

工会具有维护、建设、参与、教育四项基本职能。高校工会在构建和谐校园中,应从发挥桥梁和纽带作用、履行维权职能与促进劳动关系和谐、推进学校民主政治建设、构建和谐互动的师生关系、开展寓教于乐的文体活动、探索构建和谐校园的新... 详细信息

工会具有维护、建设、参与、教育四项基本职能。高校工会在构建和谐校园中,应从发挥桥梁和纽带作用、履行维权职能与促进劳动关系和谐、推进学校民主政治建设、构建和谐互动的师生关系、开展寓教于乐的文体活动、探索构建和谐校园的新途径与新方法等方面发挥应有作用。

关键词：和谐校园高校工会作用

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新时期坚定理想信念的重要性研究

安徽理工大学学报（社会科学版） 2016年第6期18卷 47-50页

作者：洪江如安徽理工大学纪委安徽淮南232001

习近平总书记反复强调和告诫全党必须具有坚定的理想信念。在全面建成小康社会,实现中华民族伟大复兴中国梦的进程中,进一步坚定党员尤其是党员领导干部的理想信念尤为重要。当前,我们要清醒认识坚定理想信念的重要意义和现实意义,着力... 详细信息

习近平总书记反复强调和告诫全党必须具有坚定的理想信念。在全面建成小康社会,实现中华民族伟大复兴中国梦的进程中,进一步坚定党员尤其是党员领导干部的理想信念尤为重要。当前,我们要清醒认识坚定理想信念的重要意义和现实意义,着力解决理想信念方面存在的模糊、动摇、丧失等问题,使党员干部真学真懂真信真用马克思主义,矢志不渝地为中国特色社会主义共同理想和共产主义远大理想而奋斗。

关键词：理想信念习近平党员干部共产主义