检索结果-南通市图书馆

Size-dependent thermomechanical vibration characteristics of rotating pre-twisted functionally graded shear deformable microbeams

引用

Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1015-1032页

作者： Songye JIN Bo ZHANG Wuyuan ZHANG Yuxing wang Huoming SHEN Jing wang juan LIU School of Mechanics and Aerospace Engineering Southwest Jiaotong UniversityChengdu 610031China School of Mechanical Engineering Southwest Jiaotong UniversityChengdu 610031China School of Mechanical and Electrical Engineering Southwest Petroleum UniversityChengdu 610500China

A three-dimensional(3D)thermomechanical vibration model is developed for rotating pre-twisted functionally graded(FG)microbeams according to the refined shear deformation theory(RSDT)and the modified couple stress theory(MCST).The material properties are assumed to follow a power-law distribution along the chordwise *** model introduces one axial stretching variable and four transverse deflection variables including two pure bending components and two pure shear *** complex modal analysis and assumed mode methods are used to solve the governing equations of motion under different boundary conditions(BCs).Several examples are presented to verify the effectiveness of the developed *** coupling the slenderness ratio,gradient index,rotation speed,and size effect with the pre-twisted angle,the effects of these factors on the thermomechanical vibration of the microbeam with different BCs are *** is found that with the increase in the pre-twisted angle,the critical slenderness ratio and gradient index corresponding to the thermal instability of the microbeam increase,while the critical material length scale parameter(MLSP)and rotation speed *** sensitivity of the fundamental frequency to temperature increases with the increasing slenderness ratio and gradient index,and decreases with the other increasing ***,the size effect can suppress the dynamic stiffening effect and enhance the Coriolis ***,the mode transition is quantitatively demonstrated by a modal assurance criterion(MAC).

关键词： thermomechanical vibration rotating pre-twisted functionally graded(FG)microbeam refined shear deformation theory(RSDT) modified couple stress theory(MCST) modal assurance criterion(MAC)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

E2E-MFERC:AMulti-Face Expression Recognition Model for Group Emotion Assessment

引用

Computers, Materials & Continua 2024年第4期79卷 1105-1135页

作者： Lin wang juan Zhao Hu Song Xiaolong Xu Jiangsu Key Laboratory of Big Data Security&Intelligent Processing Nanjing University of Posts and TelecommunicationsNanjing210042China School of Network Security Jinling Institute of TechnologyNanjing211169China State Grid Jiangsu Electric Power Company Limited Nanjing210000China School of Computer Science Nanjing University of Posts and TelecommunicationsNanjing210042China

In smart classrooms, conducting multi-face expression recognition based on existing hardware devices to assessstudents’ group emotions can provide educators with more comprehensive and intuitive classroom effect analysis,thereby continuouslypromotingthe improvementof teaching ***,most existingmulti-face expressionrecognition methods adopt a multi-stage approach, with an overall complex process, poor real-time performance,and insufficient generalization ability. In addition, the existing facial expression datasets are mostly single faceimages, which are of low quality and lack specificity, also restricting the development of this research. This paperaims to propose an end-to-end high-performance multi-face expression recognition algorithm model suitable forsmart classrooms, construct a high-quality multi-face expression dataset to support algorithm research, and applythe model to group emotion assessment to expand its application value. To this end, we propose an end-to-endmulti-face expression recognition algorithm model for smart classrooms (E2E-MFERC). In order to provide highqualityand highly targeted data support for model research, we constructed a multi-face expression dataset inreal classrooms (MFED), containing 2,385 images and a total of 18,712 expression labels, collected from smartclassrooms. In constructing E2E-MFERC, by introducing Re-parameterization visual geometry group (RepVGG)block and symmetric positive definite convolution (SPD-Conv) modules to enhance representational capability;combined with the cross stage partial network fusion module optimized by attention mechanism (C2f_Attention),it strengthens the ability to extract key information;adopts asymptotic feature pyramid network (AFPN) featurefusion tailored to classroomscenes and optimizes the head prediction output size;achieves high-performance endto-end multi-face expression detection. Finally, we apply the model to smart classroom group emotion assessmentand provide design refe

关键词： Multi-face expression recognition smart classroom end-to-end detection group emotion assessment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asperuloside Promotes Apoptosis of Cervical Cancer Cells through Endoplasmic Reticulum Stress-Mitochondrial Pathway

引用

Chinese Journal of Integrative Medicine 2024年第1期30卷 34-41页

作者： QI Zhi-min wang Xia LIU Xia ZHAO juan Medical Examination Center Hebei Province Hospital of Chinese MedicineShijiazhuang(050011)China Department of Gynaecology and Obstetrics Hebei Province Hospital of Chinese MedicineShijiazhuang(050011)China Experimental Center for Teaching Hebei Medical UniversityShijiazhuang(050017)China

Objective: To investigate the effects of asperuloside on cervical cancer based on endoplasmic reticulum(ER) stress and mitochondrial pathway. Methods: Different doses(12.5–800 μg/mL) of asperuloside were used to treat cervical cancer cell lines Hela and CaSki to calculate the half maximal inhibitory concentration(IC_(50)) of asperuloside. The cell proliferation was analyzed by clone formation assay. Cell apoptosis, intracellular reactive oxygen species(ROS) and mitochondrial membrane potential were determined by flow cytometry. The protein expressions of cleaved-caspase-3, Bcl-2, Bax, Cyt-c, cleaved-caspase-4 and glucose-regulated protein 78(GRP78) were analyzed by Western blot. And the inhibitor of ER stress, 4-phenyl butyric acid(4-PBA) was used to treat cervical cancer cells to further verify the role of ER stress in the apoptosis of cervical cancer cells induced by asperuloside. Results: Asperuloside of 325, 650, and 1300 μg/mL significantly inhibited the proliferation and promoted apoptosis of Hela and CaSki cells(P<0.01). All doses of asperuloside significantly increased intracellular ROS levels, reduced mitochondrial membrane potential, significantly reduced Bcl-2 protein expression level, and increased Bax, Cyt-c, GRP78 and cleaved-caspase-4 expressions(P<0.01). In addition, 10 mmol/L 4-PBA treatment significantly promoted cell proliferation and reduced apoptosis(P<0.05), and 650 μg/mL asperuloside could reverse 4-PBA-induced increased cell proliferation, decreased apoptosis and cleaved-caspase-3,-4 and GRP78 protein expressions(P<0.05). Conclusion: Our study revealed the role of asperuloside in cervical cancer, suggesting that asperuloside promotes apoptosis of cervical cancer cells through ER stress-mitochondrial pathway.

关键词： asperuloside Chinese medicine cervical cancer endoplasmic reticulum stress mitochondrial damage apoptosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of comorbid subthreshold depressive symptoms on cancerrelated fatigue and complications in adults with leukemia

引用

World Journal of Psychiatry 2024年第7期14卷 1009-1016页

作者： Yue-Xian Liu juan wang Department of Hematology Central Hospital Affiliated to Shandong First Medical UniversityJinan 250013Shandong ProvinceChina

BACKGROUND Patients not only experience symptoms caused by cancer but also suffer from the accompanying psychological ***,these patients do not have high quality of *** to the World Health Organization,the incidence of leukemia in China in 2020 was 5.1/100000,the mortality rate was 3.3/100000,and the prevalence rate was 16.7/***,it is important to examine the influence of comorbid subthreshold depressive symptoms on leukemia *** To determine the impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in leukemia patients,thereby providing a basis for early diagnosis and treatment in clinical *** A questionnaire survey was conducted among leukemia patients admitted to a tertiary hospital in Xi'an,Shaanxi Province,China,from August 2022 to December *** with a score>16 on the Chinese Classification of Mental Disorders(CCMD-3)and a Hamilton Depression Rating Scale score of 8-17 were classified as the subthreshold depressive group(n=95),while 100 leukemia patients admitted during the same period were classified as the control *** were collected using Epidata 3.1 software,and comparisons were made between the two groups regarding general clinical data,the Piper Fatigue Scale(PFS),the Pittsburgh Sleep Quality Index(PSQI),the Numeric Rating Scale for pain assessment,laboratory indicators,and the occurrence of *** In this survey,120 leukemia patients with depression were preliminarily screened,95 patients with subthreshold depression were ultimately selected as the subthreshold depression group,and 100 leukemia patients admitted during the same period were enrolled as the normal *** of basic clinical data between the two groups revealed no significant differences in age,sex,body mass index,cognitive function,or comorbidity with other chronic ***,there were statistically significant differences in the use of radiotherapy

关键词： Subthreshold depression Leukemia Cancer-related fatigue Complications Minor depression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Human-like adrenal features in Chinese tree shrews revealed by multi-omics analysis of adrenal cell populations and steroid synthesis

引用

Zoological Research 2024年第3期45卷 617-632页

作者： Jing-Hang Jiang Yi-Fu wang Jie Zheng Yi-Ming Lei Zhong-Yuan Chen Yi Guo Ya-Jie Guo Bing-Qian Guo Yu-Fang Lv hong-hong wang juan-juan Xie Yi-Xuan Liu Ting-Wei Jin Bi-Qi Li Xiao-Shu Zhu Yong-Hua Jiang Zeng-Nan Mo Center for Genomic and Personalized Medicine Guangxi Collaborative Innovation Center for Genomic and Personalized MedicineGuangxi Key Laboratory for Genomic and Personalized MedicineGuangxi Medical UniversityNanningGuangxi 530021China Department of Urology First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530021China Reproductive Medicine Center Jingmen People’s HospitalJingChu University of Technology Affiliated Central HospitalJingmenHubei 448000China School of Computer Science and Engineering Yulin Normal UniversityYulinGuangxi 537000China Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry Guangxi Medical UniversityNanningGuangxi 530021China Department of Pathology Second Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530007China Department of Obstetrics and Gynecology Second Affiliated Hospital of Guangxi Medical UniversityNanningGuangxi 530007China

The Chinese tree shrew(Tupaia belangeri chinensis)has emerged as a promising model for investigating adrenal steroid synthesis,but it is unclear whether the same cells produce steroid hormones and whether their production is regulated in the same way as in ***,we comprehensively mapped the cell types and pathways of steroid metabolism in the adrenal gland of Chinese tree shrews using single-cell RNA sequencing,spatial transcriptome analysis,mass spectrometry,and *** compared the transcriptomes of various adrenal cell types across tree shrews,humans,macaques,and *** showed that tree shrew adrenal glands expressed many of the same key enzymes for steroid synthesis as humans,including CYP11B2,CYP11B1,CYB5A,and *** analysis confirmed the production of aldosterone,cortisol,and dehydroepiandrosterone but not dehydroepiandrosterone sulfate in the tree shrew adrenal ***,genes in adrenal cell types in tree shrews were correlated with genetic risk factors for polycystic ovary syndrome,primary aldosteronism,hypertension,and related disorders in humans based on genome-wide association ***,this study suggests that the adrenal glands of Chinese tree shrews may consist of closely related cell populations with functional similarity to those of the human adrenal *** comprehensive results(publicly available at http://***:16245/scAGMap/)should facilitate the advancement of this animal model for the investigation of adrenal gland disorders.

关键词： Tree shrew Adrenal gland Dehydroepiandrosterone Genome-wide association studies Disease model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

C2-phenyl-substituted benzimidazolium-based covalent organic framework as efficient catalyst for CO_(2) conversion without solvents,metals,and cocatalysts

引用

Science China Chemistry 2024年第2期67卷 551-557页

作者： Zhenzhen Wu Jing wang Lili Liu Shang Guo juan Li Xianming Zhang Shanxi Institute for Functional Food Shanxi Agricultural UniversityTaiyuan030031China Institute of Crystalline Materials Shanxi UniversityTaiyuan030006China Key Laboratory of Interface Science and Engineering in Advanced Materials College of ChemistryTaiyuan University of TechnologyTaiyuan030024China

Covalent organic frameworks(COFs) are a potential platform for carbon dioxide(CO_(2)) conversion owing to their periodic permanent porosity,adjustable structure,and chemical *** good catalytic performance in CO_(2) conversion,collaborative multifunctions should be strategically integrated into the catalytic system design and *** this study,a four-in-one high-efficiency catalyst was synthesized and tested for CO_(2) cycloaddition to form cyclic *** obtained Tp-MPB-BrCOF had a high nitrogen content,which enhanced its CO_(2) affinity through substantial Lewis acid-base or dipole-quadrupole interactions;moreover,the acid(protons transferring from oxygen(–OH) to nitrogen(–NH)),hydrogen bond donor(hydroxyl group),and Br-(nucleophile group) served as three active sites,further improving the catalyst *** results provide a basis for designing efficient and stable CO_(2)-conversion catalysts.

关键词： covalent organic framework C2-phenyl-substituted benzimidazolium CO_(2)conversion four-in-one catalyst

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surface iodine and pyrenyl-graphdiyne co-modified Bi catalysts for highly efficient CO_(2) electroreduction in acidic electrolyte

引用

Nano Research 2024年第4期17卷 2381-2387页

作者： Min Zhang juan wang Xin Rong Xiu-Li Lu Tong-Bu Lu MOE International Joint Laboratory of Materials Microstructure Institute for New Energy Materials and Low Carbon TechnologiesSchool of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China

CO_(2) electroreduction to formic acid/formate would contribute to alleviating the energy and climate *** work reports a Bi-based catalyst derived from the in-situ electroreduction of Bi_(2)O_(2)CO_(3) modified with iodine and pyrenyl-graphdiyne(PGDY)on the surface for efficient electroreduction of CO_(2) in acidic electrolyte,with a high partial current density of 98.71 mA·cm^(-2) and high Faradaic efficiency(FE)>90%over the potential range from^(-1).2 to-1.5 V *** hydrogen electrode(RHE),as well as the long-term operational stability over 240 h without degradation in H-type *** results and density function theory calculations show that the synergistic effect of surface iodine and PGDY is responsible for this active and extremely stable process of CO_(2) electroreduction via lowering the energy barriers for formation of*OCHO intermediate,suppressing the competitive HER by enhancing the concentration of both K+and CO_(2) at reaction interface,as well as preventing the dissolution and re-deposition of active Bi atoms on surface during catalytic *** work provides new insight into designing highly active and stable electrocatalysts for CO_(2) reduction.

关键词： CO_(2) reduction electrocatalysis Bi-based catalysts acidic electrolyte

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of immune cell interactions in alcohol-associated liver diseases

引用

肝脏研究（英文） 2024年第2期8卷 72-82页

作者： Xianda wang juan wang Haodong Peng Li Zuo Hua wang Innovation and Entrepreneurship Laboratory for College Students Anhui Medical UniversityHefeiAnhuiChina Inflammation and Immune-Mediated Diseases Laboratory of Anhui Province Anhui Medical UniversityHefeiAnhuiChina Department of Oncology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhuiChina Innovation and Entrepreneurship Laboratory for College Students Anhui Medical UniversityHefeiAnhuiChina The First School of Clinical Medicine Anhui Medical UniversityHefeiAnhuiChina Innovation and Entrepreneurship Laboratory for College Students Anhui Medical UniversityHefeiAnhuiChina Laboratory of Molecular Biology Department of BiochemistrySchool of Basic Medical SciencesAnhui Medical UniversityHefeiAnhuiChina

Research on inflammatory response,liver injury,and immune regulation has demonstrated that the intricate interactions among immune cells constitute a critical regulatory *** consumption alters the liver microenvironment,triggering inflammation and immune *** the inhibitory,cooperative,and synergistic effects among lymphocytes and myeloid cells may reveal the core mechanisms of alcohol-associated liver disease(ALD)pathogenesis and identify promising therapeutic *** review seeks to elucidate the intricate and multifaceted interactions among immune cells,encompassing both direct cellular interactions and the secretion of various effector *** is essential to underscore that these interactions have broader and more complex roles in ALD than the activities of individual immune cell *** interactions play a crucial role in mutually regulating one another,thereby preserving the homeostasis of the inflammatory and immune response in the liver *** these immune cell interactions is anticipated to offer a novel approach to the prevention and treatment of ALD.

关键词： Immune cell Cell interactions Inflammation Alcohol-associated liver disease (ALD)

来源：评论

学校读者我要写书评

暂无评论

Intracellular redox potential-driven live-cell synthesis of CdSe quantum dots in Staphylococcus aureus

引用

Science China Chemistry 2024年第3期67卷 990-999页

作者： Cai-Qin Wu An-An Liu Xu Li Jia-Wei Tu juan Kong Ling-Ling Yang Jian-hong Jia Chuan wang Bin Hu Zhi-Xiong Xie Dai-Wen Pang The Institute for Advanced Studies College of Chemistry and Molecular SciencesCollege of Life SciencesHubei Key Laboratory of Cell HomeostasisWuhan UniversityWuhan 430072China Research Center for Analytical Sciences College of ChemistryState Key Laboratory of Medicinal Chemical BiologyTianjin Key Laboratory of Biosensing and Molecular RecognitionFrontiers Science Center for New Organic MatterFrontiers Science Center for Cell Responsesand Haihe Laboratory of Sustainable Chemical TransformationsNankai UniversityTianjin 300071China

Biosynthesized semiconductor quantum dots(QDs) have bright fluorescence,adjustable particle sizes,and environmental friendliness,endowing them with convenience and potential for biological *** to the unclear mechanism of the cellular environment on the live-cell synthesis of QDs,it is still difficult to regulate their optical ***,the critical role of the intracellular redox environment in regulating the fluorescence properties of biosynthesized CdSe QDs in Staphylococcus aureus(***) has been *** glutathione peroxidase(GPx) activity directly affects the intracellular H_(2)O_(2) produced in the SeO_(3)^(2-) reduction,which further manipulates the glutathione redox cycle to determine the content of low-valence *** a result,the fluorescence intensity of the synthesized CdSe QDs increases by 60% in the GPx overexpressed *** cellular redox potential that is controlled by the GSH redox cycle provides the driving force for the reduction of SeO_(3)^(2-),facilitating the synthesis of CdSe QDs in *** *** proposed mechanism of the cellular redox state provides a new perspective for regulating the synthesis of semiconductor nanomaterials in live cells.

关键词： redox H_(2)O_(2) peroxidase quantum dot Staphylococcus aureus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Modeling Near-Field Impulsive Waves Generated by Deformable Landslide Using the HBP Model Based on the SPH Method

引用

Journal of Ocean University of China 2024年第2期23卷 328-344页

作者： wang Wei WEI Weicheng CHAI Bo XIA Hao wang Yang DU juan LIU Jizhixian School of Environmental Studies China University of GeosciencesWuhan 430078China Hubei Key Laboratory of Yangtze Catchment Environmental Aquatic Science Wuhan 430078China Faculty of Engineering China University of GeosciencesWuhan 430074China Research Center for Geohazards Monitoring and Warning in Three Gorges Reservoir Wanzhou 404000China

Landslide-generated impulsive waves(LGWs)in reservoir areas can seriously threaten waterway safety as well as hu-man life and properties around the two side *** risk reduction and mitigation of such a hazard require the accurate prediction of near-field wave characteristics,such as wave amplitude and ***,near-field LGW involves complicated fluid-solid ***,the wave characteristics are closely related to various aspects,including the geometry and physical features of the slide,river,and body of ***,the empirical or analytical methods used for rough estimation cannot derive accurate results,especially for deformable landslides,due to their significant geometry changes during the sliding *** this study,the near-field waves generated by deformable landslides were simulated by smoothed particle hydrodynamics(SPH)based on multi-phase *** deformable landslides were generalized as a kind of viscous flow by adopting the Herschel-Bulkley-Papanastasiou(HBP)-based nonNewtonian rheology *** HBP model is capable of producing deformable landslide dynamics even though the high-speed sliding process is *** this study,an idealized experiment case originating from Lituya LGW and a practical case of Gongjiafang LGW were reproduced for verification and *** simulation results of both cases show satisfactory consistency with the experiment/investigation data in terms of landslide movement and near-field impulsive wave characteristics,thus indicating the applicability and accuracy of the proposed ***,the effects of the HBP model’s rheological parameters on the landslide dynamics and near-field wave characteristics are discussed,providing a parameter calibration method along with sug-gestions for further applications.

关键词： deformable landslide impulsive waves near-field SPH nonNewtonian fluids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：