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Hepatobiliary & Pancreatic Diseases International 2019年第4期18卷 313-320页

作者： Shi-jie Wang Xiao-Ying si Zhi-Bin Cai Yan-Ming Zhou Department of Hepatobiliary and Pancreatovascular Surgery First Affiliated Hospital of Xiamen University

Background:Frequent recurrent hepatic metastasis after hepatic metastasectomy is a major obstacle in the treatment of colorectal liver metastasis(CRLM).We performed the present systematic review to evaluate the short-and long-term outcomes after repeat hepatectomy for recurrent CRLM and determine factors associated with survival in these *** sources:An electronic search of PubMed database was undertaken to identify all relevant peerreviewed papers published in English between January 20 0 0 and July *** ratios(HR)with 95%confidence interval(95%CI)were calculated for prognostic factors of overall survival(OS).Results:The search yielded 34 studies comprising 3039 patients,with a median overall morbidity of 23%(range 8%–71%),mortality of 0(range 0–6%),and 5-year OS of 42%(range 17%–73%).Pooled analysis showed that primary T3/T4 stage tumor(HR=1.94;95%CI:1.04–3.63),multiple tumors(HR=1.49;95%CI:1.10–2.01),largest liver lesion≥5 cm(HR=1.89;95%CI:1.11–3.23)and positive surgical margin(HR=1.80;95%CI:1.09–2.97)at initial hepatectomy,and high serum level of carcinoembryonic antigen(HR=1.87;95%CI:1.27–2.74),disease-free interval≤12 months(HR=1.34;95%CI:1.10–1.62),multiple tumors(HR=1.64;95%CI:1.32–2.02),largest liver lesion≥5 cm(HR=1.85;95%CI:1.34–2.56),positive surgical margin(HR=2.25;95%CI:1.39–3.65),presence of bilobar disease(HR=1.62;95%CI:1.19–2.20),and extrahepatic metastases(HR=1.60;95%CI:1.23–2.09)at repeat hepatectomy were significantly associated with poor OS.

关键词： Colorectal cancer Metastasectomy Prognosis Meta-analysis

A Self-supporting,Surface Carbonized Filter Paper Membrane for Efficient Water-in-Oil Emulsion Separation

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Chinese Journal of Polymer Science 2021年第2期39卷 181-188,I0006页

作者： Jiang-Yong-Quan Cao si-Chong Chen jie Zhang Yang-Yang Xie Yu-Zhong Wang The Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials National Engineering Laboratory of Eco-Friendly Polymeric Materials(Sichuan)Sichuan UniversityCollege of ChemistrySichuan UniversityChengdu 610064China

Due to the important role of oil source in our life,the separation of water-in-oil emulsion is urgent and *** seperation technology has been an efficient and widely used method in separating oil-water ***,we report a versatile approach to fabricate surface carbonized membranes with self-standing property from biomass-derived precursor by synergistic charring of phytic acid,arginine and filter *** obtained membrane exhibited superhydrophobicity in oil,excellent fouling resistance,and self-supporting *** membrane can be cycle-used at least 12 times with high permeation flux(up to 1380 L·m^(-2)·h^(-1))and separation efficiency(up to 99.4%).

关键词： Water-in-oil emulsion separation Filter paper membrane Surface carbonized Self-supporting

Long-term outcomes of combined hepatocellular-cholangiocarcinoma after hepatectomy or liver transplantation: A systematic review and meta-analysis

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Hepatobiliary & Pancreatic Diseases International 2019年第1期18卷 12-18页

作者： De-Bang Li Xiao-Ying si Shi-jie Wang Yan-Ming Zhou Department Ⅲ of General Surgery the First Hospital of Lanzhou University Department of Hepatobiliary & Pancreatovascular Surgery First Affiliated Hospital of Xiamen University

Background: Combined hepatocellular-cholangiocarcinoma(cHCC-CC) is a rare primary liver malignancy. We conducted a systematic review and meta-analysis to assess the evidence available on the long-term outcomes of cHCC-CC patients after either hepatectomy or liver transplantation(LT). Data Sources: Relevant studies published between January 2000 and January 2018 were identified by searching Pub Med and Embase and reviewed systematically. Data were pooled using a random-effects model. Results: A total of 42 observational studies involving 1691 patients(1390 for partial hepatectomy and 301 for LT) were included in the analysis. The median tumor recurrence and 5-year overall survival(OS) rates were 65%(range 38%–100%) and 29%(range 0–63%) after hepatectomy versus 54%(range 14%–93%) and 41%(range 16%–73%) after LT, respectively. Meta-analysis found no significant difference in OS and tumor recurrence between LT and hepatectomy groups. Conclusion: Hepatectomy rather than LT should be considered as the prior treatment option for cHCC-CC.

关键词： Combined hepatocellular-cholangiocarcinoma Liver transplantation Hepatectomy Treatment Prognosis

Humidity Sensitive Properties of a silicone-containing Polyelectrolyte Material

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Chinese Chemical Letters 2006年第1期17卷 73-76页

作者： Mu jie YANG Zong Wu YAO You si CHEN Yang LI Department of polymer science and Engineering Zhejiang University Hangzhou 310027

Resistive-type film humidity sensors were prepared with a silicone-containing polyelectrolyte （si-PE） and their humidity sensitive properties have been investigated. The sensors so obtained show high sensitivity to humidity variation over a wide range of RH （20-96%）. In addition, they exhibit high reversibility, quick response and well long-term stability.

关键词： Humidity sensor silicone-containing polyelectrolyte humidity sensitive properties.

Cumulative Risk Assessment of Exposure to Heavy Metals through Aquatic Products in China

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Biomedical and Environmental Sciences 2021年第8期34卷 606-615页

作者： WANG Hui MAO Wei Feng JIANG Ding Guo LIU si jie ZHANG Lei NHC Key Laboratory of Food Safety Risk Assessment Chinese Academy of Medical Science Research UnitChina National Center for Food Safety Risk AssessmentBeijing 100022China Department of Physical and Chemical Test Jilin Provincial Center for Disease Control and PreventionChangchun 130062JilinChina

Objective This study aimed to assess the risk of cumulative exposure to Pb,Cd,Hg,and iAs through aquatic products consumed by Chinese *** Heavy metal concentration data were obtained from the national food contamination monitoring program during 2013–*** data were derived from the China National Food Consumption Survey in 2014 and the relative potency factor(RPF)method was used to estimate cumulative exposure for neurotoxicity and *** The results demonstrated that the cumulative exposure based on neurotoxicity was below the lower confidence limit on benchmark doses of lead(BMDL01)for nephrotoxicity and the cumulative exposures were all lower than the provisional tolerable monthly intake(PTMI)of ***,the margin of exposure values(MOEs)of the cumulative exposures for neurotoxicity in the 2–6 year-old group was close to 1 and the cumulative exposure level for nephrotoxicity accounted for 90.21%of the *** The cumulative exposures of the 2–6 year-old group to the four heavy metals did not reach(but came close to)the corresponding safety threshold for both neurotoxicity and *** that there are still other food sources of these four heavy metals,it is necessary to more closely study their cumulative health effects.

关键词： Arsenic Lead Cadmium Mercury Aquatic products Heavy metals

RF design of 650-MHz 2-cell cavity for CEPC

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Nuclear Science and Techniques 2019年第10期30卷 95-104页

作者： hong-Juan Zheng jie Gao Ji-Yuan Zhai Peng Sha Fei-si He Zhong-Quan Li Song Jin Zheng-Hui Mi Jian-Kui Hao Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Institute of Heavy Ion Physics&State Key Laboratory of Nuclear Physics and TechnologyPeking UniversityBeijing 100871China

In order to meet the requirements of the Circular Electron Positron Collider(CEPC),a 650-MHz 2-cell superconducting cavity was proposed and *** this study,we show the progress in the cavity design for the *** radio frequency and mechanical designs are ready for the first design version,called CEPC-V1.A cryomodule,which consists of two 650-MHz 2-cell cavities,was scheduled the last ***,prototypes of the 2-cell cavity based on this design were fabricated and tested the following *** vertical test results show that multipacting(MP)exists from 10 to 19 MV/*** will increase the operational risk of the CEPC,while the continuous-wave operation for the 650-MHz cavity is 19.7 MV/*** trapped modes were also found,which exist because of the identical half-cell ***,a few improvements regarding MP and more efficient extraction of higher-order mode power are discussed.A new type of cavity design,called CEPC-V2,is also discussed in this paper.

关键词： 650-MHz cavity Multipacting Higher-order mode

A mixed-valent high spin(μ-hydroxo)dicobalt(Ⅱ/Ⅲ) complex and its end-on type dioxygen adduct: synthesis, geometric and electronic structure studies

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Science China Chemistry 2021年第10期64卷 1693-1697页

作者： Ceng-Ceng Du si-Jun Xie Dan-Dan Zhai Zhang-jie Shi Huayi Fang Department of Chemistry Fudan UniversityShanghai 200433China School of Materials Science and Engineering Tianjin Key Lab for Rare Earth Materials and ApplicationsNankai UniversityTianjin 300350China

A mixed-valent high spin (μ-hydroxo)dicobalt(Ⅱ/Ⅲ) complex bearing N,N′-bis(5-tertbutylsalicylidene)-1,2-diaminobenzene(Salophen^(tBu)) ligand was synthesized by reacting (Salophen^(tBu))Co(Ⅱ)(Py) with O_(2) at low *** complex was isolated and structurally characterized by single crystal X-ray diffraction and infrared *** measurement showed a quartet ground state for this complex at room temperature,which was also supported by electron paramagnetic resonance (EPR)*** investigations indicated the deviation of the equatorial N_(2)O_(2) coordination geometry around the Co(Ⅱ) center from plane stabilized the quartet *** end-on type O_(2) adduct of this (μ-hydroxo)dicobalt(Ⅱ/Ⅲ) complex was isolated as dark-brown crystals and structurally and spectroscopically *** measurement of this compound in solid state at room temperature presented an isotropic singlet at g~2,revealing the superoxide-like electronic feature of the coordinated O_(2) and was in line with the calculation *** reactivity of the Co(Ⅲ)-O_(2) complex with N-hydroxyphthalimide,which can act as hydrogen atom donor,was also examined.

关键词： dicobalt complex mixed-valent electronic structure dioxygen adduct

Sulfonated carbon catalyzed oxidation of aldehydes to carboxylic acids by hydrogen peroxide

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Journal of Energy Chemistry 2013年第4期22卷 659-664页

作者： Lipeng Zhou Beibei Dong si Tang hong Ma Chen Chen jie Xu Xiaomei Yang jie Xu College of Chemistry and Molecular Engineering Zhengzhou University State Key Laboratory of Catalysis Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of Sciences

Sulfonated carbon as a strong and stable solid acid catalyst exhibited excellent catalytic performance in various acid-catalyzed reactions. Here, sulfonated carbon, as catalyst for oxidation reaction, was prepared via the carbonization of starch followed by sulfonation with concentrated sulfuric acid. N2 physisorption, X-ray diffraction, Fourier transform infrared spectroscopy, X-ray fluorescence and acid-base titration were used to characterize the obtained materials. The catalytic activity of sulfonated carbon was studied in the oxidation of aldehydes to carboxylic acids using 30 wt% H2O2 as oxidant. This oxidation protocol works well for various aldehydes including aromatic and aliphatic aldehydes. The sulfonated carbon can be recycled for three times without obvious loss of activity.

关键词： aldehyde carboxylic acid oxidation hydrogen peroxide sulfonated carbon

Anatomical features and technical difficulties in laparoscopic pancreaticoduodenectomy with various superior mesenteric artery-first approaches

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Hepatobiliary & Pancreatic Diseases International 2023年第2期22卷 115-118页

作者： jie Hua si Shi Bo Zhang Jin Xu Wei Wang Department of Pancreatic Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Pancreatic Cancer Institute Shanghai 200032China Pancreatic Cancer Institute Fudan UniversityShanghai 200032China

Laparoscopic pancreaticoduodenectomy(LPD) at its early stage failed to demonstrate the superiority compared with open pancreaticoduodenectomy(OPD) [1]. The well-known randomized trial, LEOPARD-2, was even terminated due to the safety issue [2], but recent researches [3,4] revealed that LPD is technically safe and feasible with acceptable rates of morbidity and mortality and therefore, gains popularity recently.

关键词： mortality artery terminated

Dek219 encodes the DICER-LIKE1 protein that affects chromatin accessibility and kernel development in maize

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Journal of Integrative Agriculture 2023年第10期22卷 2961-2980页

作者： XIE si-di TIAN Ran ZHANG Jun-jie LIU Han-mei LI Yang-ping HU Yu-feng YU Guo-wu HUANG Yu-bi LIU Ying-hong State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130P.R.China College of Life Science Sichuan Agricultural UniversityYa’an 625014P.R.China College of Agronomy Sichuan Agricultural UniversityChengdu 611130P.R.China Maize Research Institute Sichuan Agricultural UniversityChengdu 611130P.R.China

Chromatin accessibility plays a vital role in gene transcriptional ***,the regulatory mechanism of chromatin accessibility,as well as its role in regulating crucial gene expression and kernel development in maize(Zea mays)are poorly *** this study,we isolated a maize kernel mutant designated as defective kernel219(dek219),which displays opaque endosperm and embryo ***219 encodes the DICER-LIKE1(DCL1)protein,an essential enzyme in mi RNA *** of function of Dek219 results in significant reductions in the expression levels of most mi RNAs and histone *** research showed that the Heat shock transcription factor17(Hsf17)-Zm00001d016571 module may be one of the factors affecting the expression of histone *** results for transposase-accessible chromatin sequencing(ATAC-seq)indicated that the chromatin accessibility of dek219 is altered compared with that of wild type(WT),which may regulate the expression of crucial genes in kernel *** analyzing differentially expressed genes(DEGs)and differentially accessible chromatin regions(ACRs)between WT and dek219,we identified 119 candidate genes that are regulated by chromatin accessibility,including some reported to be crucial genes for kernel *** together,these results suggest that Dek219 affects chromatin accessibility and the expression of crucial genes that are required for maize kernel development.

关键词： maize kernel development chromatin accessibility histone miRNA