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Dental focal infection-induced ventricular and spinal canal empyema: A case report

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World Journal of Clinical Cases 2020年第14期8卷 3114-3121页

作者： Hang Xue Xiao-Hui Wang Lin Shi Qiang Wei Yi-Ming Zhang hong-fa yang Department of Neurotraumatic Surgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Neurosurgery The Affiliated Hospital of Changchun University of Traditional Chinese MedicineChangchun 130021Jilin ProvinceChina Department of Neurosurgery Dong’e Hospital Affiliated to Shandong First Medical UniversityDong’e 252200Shandong ProvinceChina

BACKGROUND Dental focal infection-induced ventricular and spinal canal empyema is an extremely rare,severe,acute disease that is clinically associated with extremely high morbidity and *** cerebrospinal fluid(CSF)bacterial culture is time-consuming,with a low positive rate,which frequently results in severe irreversible *** next-generation sequencing technique is an emerging pathogenic microorganism detection method that can obtain results in a short time with high accuracy,thus providing great assistance in the clinical diagnosis and treatment of this *** SUMMARY This paper reports a rare case of dental focal infection-induced ventricular and spinal canal *** the course of treatment at a local hospital,the patient had negative results from repeated CSF bacterial cultures and was empirically given vancomycin *** transfer to our hospital,the nextgeneration sequencing technique was adopted to determine that the pathogenic microorganisms were multiple anaerobic infectious bacteria derived from the oral *** antibiotic therapeutic scheme was adjusted in a timely manner,and the ventricular and spinal canal inflammation was also ***,the antibiotics that had been applied at the local hospital were not able to cover all pathogenic microorganisms,which resulted in irreversible injury to the brain stem,finally leading to patient *** Dental focal infection-induced ventricular and spinal canal empyema is an extremely rare,severe,acute disease with high morbidity and *** delay in diagnosis and treatment will result in irreversible *** early application of the next-generation sequencing technique can obtain results in a short time and clarify a *** antibiotic treatment combined with suitable surgical intervention is the key to managing this disease.

关键词： Ventricular empyema Next-generation sequencing Dental focal infection Antibiotics Surgery Case report

Transorbital nonmissile penetrating brain injury: Report of two cases

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World Journal of Clinical Cases 2020年第2期8卷 471-478页

作者： Hang Xue Wei-Tao Zhang Guang-Ming Wang Lin Shi Yi-Ming Zhang hong-fa yang Department of Neurotraumatic Surgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Neurosurgery The Affiliated Hospital of Changchun University of Traditional Chinese MedicineChangchun 130021Jilin ProvinceChina Department of Neurosurgery Qilu Hospital of Shandong UniversityJi’nan 250002Shandong ProvinceChina

BACKGROUND Penetrating brain injury(PBI) is an uncommon emergency in neurosurgery, and transorbital PBI is a rare type of PBI. Reasonable surgical planning and careful postoperative management can improve the prognosis of patients CASE SUMMARY The first case is a 68-year-old male patient who was admitted to the hospital because a branch punctured his brain through the orbit for approximately 9 h after he unexpectedly fell while walking. After admission, the patient underwent emergency surgical treatment and postoperative anti-infection treatment. The patient was able to follow instructions at a 4-mo follow-up review. The other case is a 46-year-old male patient who was admitted to the hospital due to an intraorbital foreign body caused by a car accident, after which the patient was unconscious for approximately 6 h. After admission, the patient underwent emergency surgical treatment and postoperative anti-infection treatment. The patient could correctly answer questions at a 3-mo follow-up *** Transorbital PBI is a rare and acute disease. Early diagnosis, surgical intervention, and application of intravenous antibiotics can improve the prognosis and quality of life of patients.

关键词： Transorbital Nonmissile Penetrating brain injury Foreign body Case report

Photoselective vaporization of the prostate in the treatment of benign prostatic hyperplasia

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Chinese Medical Journal 2005年第19期118卷 1610-1614页

作者： FU Wei-jun hong Bao-fa yang Yong CAI Wei GAO Jiang-ping WANG Chun-yang WANG Xiao-xiong Department of Urology General Hospital of People＇s LiberationArmy Beijing 100853 China

Background The treatment of symptomatic benign prostatic hyperplasia （BPH） remains a challenge for most urologic surgeons. We studied a cumulative cohort of patients with symptomatic benign prostatic hyperplasia （BPH） who underwent photoselective vaporization of the prostate （PVP） and evaluated the efficacy and safety of this procedure. Methods A total of 196 patients with lower urinary tract obstruction symptoms secondary to BPH were treated using laser vaporization of the prostate under sacral canal anesthesia at our institutions. The therapeutic results were assessed using following variables ： the safety and efficacy of sacral anesthesia, blood loss, operative time, indwelling catheterization. Preoperative and perioperative parameters were evaluated in the international prostate symptom score （ IPSS）, quality of life score （ QoL）, maximal urinary flow rate （ Qmax）, post-void residual urine volume （PVR） and the change of sexual function. Patients were also assessed for 3-month follow up. Results PVP was performed successfully for all patients. There were 195 patients under sacral anesthesia and 1 patient under epidural anesthesia. Mean operative time was （45.2±18.5 ） minutes. The mean IPSS decreased from （26.6±3.2 ） to （5.6±1.4） and the QoL score decreased from （5.7±0.4） to （ 1.6±0. 5 ）, respectively （ P 〈 0. 05 ）, while mean Qmax increased from （6.7±2.5 ） ml/s preoperatively to （ 19.6± 2.4 ） ml/s, PVR decreased from 158.4 to 25.8 ml, respectively （ P 〈 0.05）. Average catheterization time was （ 1.8±0. 9） days. There was no significant blood loss or fluid absorption during the period of PVP. Complications consisted of transient dysuria in 3 patients （1.5%）, delayed gross hematuria in 5 patients （2. 5% ）, respectively. Significant improvement in clinical outcomes were noted as early as 3 months after PVP treatment. Conclusions PVP is considered as a high satisfaction rate by complication. Hence, PVP is a novel, safe, effective and minimal symptomatic BPH. patient a

关键词： benign prostatic hyperplasia prostatectomy laser surgery

Photoselective vaporization of the prostate in the treatment of benign prostatic hyperplasia

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中华医学杂志(英文版) 2005年第19期 28-32页

作者： FU Wei-jun,hong Bao-fa,yang Yong,CAI Wei,GAO Jiang-ping,WANG Chun-yang and WANG Xiao-xiong Department of Urology, General Hospital of People’s Liberation Army, Beijing 100853, China

Benign prostatic hyperplasia (BPH) is a common disease in aged men. The traditional transurethral resection of the prostate (TURP) has been the best standard procedure in treating BPH for decades. However, the complication morbidity associated with TURP has remained relatively constant at 18%.~1 Recently the photoselective vaporization of the prostate (PVP) with a high powered potassium-titanyl-phosphate (KTP) laser is a rapidly emerging technique and an attractive alternative for the management of obstructive BPH.~2 Early and limited clinical results of PVP have demonstrated minimally invasive techniques and equivalent efficacy and greater safety in comparison with those of TURP.~3 We evaluated our early clinical experience with PVP in the treatment of Chinese *** Wei-jun, hong Bao-fa, yang Yong, CAI Wei, GAO Jiang-ping, WANG Chun-yang and WANG Xiao-xiong

关键词： benign prostatic hyperplasia · prostatectomy · laser surgery

Two micron continuous wave laser vaporesection for the treatment of benign prostatic hyperplasia

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Asian Journal of Andrology 2008年第2期10卷 341-342页

作者： Wei-Jun Fu Bao-fa hong Yong yang Jiang-Ping Gao Lei Zhang Wei Cai Yao-Fu Chen Xiao-Xiong Wang Department of Urology Chinese People＇s Liberation Army General Hospital Military Postgraduate Medical CollegeBeijing 100853 China

I＇m Wei-Jun Fu, from Department of Urology, Chinese People＇ s Liberation Army General Hospital, Military Postgraduate Medical College, Beijing, China. We write to you to present an observation on the safety and clinical effects of RevoLix 70 W 2 micron continuous wave laser vaporesection for the treatment of obstructive benign prostatic hyperplasia （BPH）. Because of the combination of the advantages of vaporization and resection, in our experience, 2 micron wave laser vaporesection for treatment of BPH provides safe and effective relief from obstructive BPH with minimal morbidity and rare bleeding.

关键词：出血氟尿嘧啶挥发作用军事人员泌尿科学年患病率前列腺增生亚洲大陆世系人群男(雄)性

New chapter in reform and development of organ donation and transplantation in China: Embracing past, grounding in national conditions, upholding steadfast belief, and looking forward to future

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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 6-13页

作者： hong-Tao Zhao Shu-Sen Zheng Jia fan Jia-hong Dong Zhong-Hua Chen Wu-Jun Xue Qi-fa Ye Hai-Bo Wang Jing-Yu Chen Zhe Zheng Feng Huo Xiao-Shun He Miao Pu Jie Zhao Jie-Fu Huang China Organ Transplantation Development Foundation China National Human Organ Donation and Transplantation Committee The First Affiliated Hospital Zhejiang University School of Medicine Zhongshan Hospital Fudan University Beijing Tsinghua Changgung Hospital Affiliated to Tsinghua University Tongji Hospital Tongji Medical College Huazhong University of Science&Technology The First Affiliated Hospital of Xi’an Jiaotong University Zhongnan Hospital of Wuhan University Wuxi People’s Hospital Fuwai Hospital Chinese Academy of Medical Sciences General Hospital of Southern Theater Command of PLA The First Affiliated Hospital of Sun Yat-sen University

The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization(WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.

关键词： Reform Legislation Organ donation Organ transplantation Chinese mode High quality development

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黄鳝的胚胎及胚后发育

水产学报 2003年第6期27卷 505-512页

作者：周秋白吴华东吴红翔杨发群江西农业大学动物科学技术学院江西农业大学动物科学技术学院江西南昌 330045

将黄鳝的受精卵静水控温孵化后,经活体解剖和透明处理,记录黄鳝孵化时序,显微观察并拍摄黄鳝胚胎发育及胚后发育过程的形态特征。黄鳝卵圆球型,橙黄或淡黄色,沉性,卵粒重25～38mg,卵径1.7～3.1mm。受精吸水3～5min膨胀后,卵径增大至3.0... 详细信息

将黄鳝的受精卵静水控温孵化后,经活体解剖和透明处理,记录黄鳝孵化时序,显微观察并拍摄黄鳝胚胎发育及胚后发育过程的形态特征。黄鳝卵圆球型,橙黄或淡黄色,沉性,卵粒重25～38mg,卵径1.7～3.1mm。受精吸水3～5min膨胀后,卵径增大至3.0～3.7mm。黄鳝出膜时全长15～21mm,卵黄吸收完成时,全长25～35mm。黄鳝胚胎发育过程中出现具有丰富的微血管分布的胸鳍。胸鳍在胚体出膜后卵黄囊完全消失前退化。在温度26℃时,胚胎发育所需时间为168h,所需积温“度·时”值为4368;在温度32℃时,胚胎发育所需时间为144h,所需积温“度·时”值为4608。在温度32℃时,胚后发育所需时间(从出膜至卵黄全部吸收)为216h,所需积温“度·时”值为6912。26～30℃是黄鳝卵适宜的胚胎发育温度。

关键词：黄鳝孵化胚胎发育胚后发育温度

水稻窄叶突变体Narrow leaf11(nal11)的基因定位

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南方农业学报 2017年第7期48卷 1133-1138页

作者：赵久云罗洪发江燕杨旭东查仁明贵州大学农学院贵阳550025

【目的】定位和分析水稻窄叶突变体基因,为水稻叶片发育调控及株型育种提供参考依据。【方法】用甲基磺酸乙酯(EMS)诱导泸恢17,获得稳定的窄叶突变体(Narrow leaf 11,nal11),调查其与野生型泸恢17抽穗期功能叶的长和宽、分蘖数及成熟期... 详细信息

【目的】定位和分析水稻窄叶突变体基因,为水稻叶片发育调控及株型育种提供参考依据。【方法】用甲基磺酸乙酯(EMS)诱导泸恢17,获得稳定的窄叶突变体(Narrow leaf 11,nal11),调查其与野生型泸恢17抽穗期功能叶的长和宽、分蘖数及成熟期株高。对nal11和绵恢727正反交获得的F2代进行遗传分析及基因定位。【结果】nal11抽穗期剑叶、倒2叶和倒3叶的宽度与野生型泸恢17存在显著(P0.05);nal11株高为野生型泸恢17的90.3%,存在显著差异;nal11分蘖数极显著增加,为野生型的150.0%。nal11和绵恢727正反交后,F1代均表现正常叶宽,F2代叶宽发生性状分离,正常叶宽与窄叶植株数比例经χ2检验均符合3∶1,表明nal11是受核单基因控制的隐性突变。利用SSR标记将nal11定位在水稻第4号染色体RM7290和RM16720标记之间约322 kb范围内,其与2个标记的遗传距离均为0.8 c M,覆盖了32.236 kb的物理区域,在定位区域内有5个注释基因,即Os04g26834、Os04g26850、Os04g26870、Os04g26880和Os04g26841,其序列与前人克隆的窄叶基因无重复。【结论】获得一个新的水稻窄叶突变体(nal11),其窄叶性状由1个隐性核基因控制,定位于水稻第4号染色体RM7290和RM16720标记之间,对功能叶、株高和分蘖数的表型有明显影响。

关键词：水稻窄叶突变体基因定位遗传分析

基于小波变换和拟动力法的边坡地震稳定性评价方法

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岩土力学 2025年第1期46卷 88-96,109页

作者：钱法桥邓亚虹慕焕东杨楠刘凡王梦晨长安大学地质工程与测绘学院陕西西安710054 矿山地质灾害成灾机理与防控重点实验室陕西西安710054 西安理工大学岩土工程研究所陕西西安710048

结合简化Bishop法,推导了地震作用下边坡的稳定性计算公式,包括拟静力法(pseudo-static method,简称PSM)、经典拟动力法(pseudo-dynamic method,简称PDM)和修正拟动力法(modified pseudo-dynamic method,简称MPDM)。其中,修正拟动力法将土体视为Kelvin-Voigt材料,考虑了土体的黏弹特性和放大特性。在此基础上,对修正拟动力法进行了推广,使剪应力在坡顶、坡面处均为0,符合边坡应力特征。然后,基于Morlet小波分析,以El centro波为研究对象获得了地震波的频谱分布特征。通过提取峰值加速度PGA时刻的卓越频率,提出了一种考虑地震动时频特征的边坡地震稳定性评价方法。最后,将各方法与实例进行了验证。结果表明:拟动力法所需参数较少且意义明确,能够快速、准确地评价边坡地震稳定性,与时程分析方法结果接近。该研究成果可为边坡地震危险性评价、地震滑坡灾害范围分析预测、抗震应急抢险提供理论依据。

关键词：拟动力修正拟动力小波变化地震滑坡稳定性