检索结果-南通市图书馆

Non-commutative Chiral QCD2 Model

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2002年第8期38卷 217-220页

作者： YANG Zhan-Ying yuE Rui-hong HOU Bo-yu shi Kang-Jie Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China

The effective action of chiral QCD2 was studied in two-dimensional non-commutative space-time by usingpath integral approach. It is shown that vector boson has a mass generation and the effective Lagrangian contains a... 详细信息

关键词： chiral anomaly, non-commutative geometry, effective Lagrangian

Preparation of novel chiral stationary phase based on click chemistry for ligand exchange chromatography

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2009年第11期20卷 1345-1347页

作者： Chun Mei Fu hong yu shi Guang Sheng Qian Zhang Wan Li West China School of Pharmacy Sichuan University Chengdu 610041 China Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China Graduate School of the Chinese Academy of Sciences Beijing 100049 China

Click chemistry was applied to immobilize L-proline derivative onto azide-modified silica gel to give a novel chiral stationary phase （denoted as click-CSP） for ligand exchange chromatography. The developed protocol combines the benefits of operational simplicity, exceptionally mild conditions and high surface loadings. The enantioselectivity α of some DL-arnino acids on the click- CSP were found to be in the range from 1.13 to 3.46. The chromatographic resolutions of some DL-amino acids and the stability study firmly illustrate the potential of click chemistry for preparation chiral stationary phase for ligand exchange chromatography.

关键词： Click chemistry Ligand exchange chromatography Chiral stationary phase vL-amino acids

A chiral stationary phase with special hydrophobic framework for ligand-exchange chromatography

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2007年第11期18卷 1392-1394页

作者： hong yu shi Rui Juan Song yu Fu Na Yao yuan De Long Tian Bao Huang Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China Graduate School of the Chinese Academy of Sciences Beijing 100049 China

A novel chiral stationary phase （CSP1） for ligand-exchange chromatography （CLEC） was prepared by firstly using dimethylchlorosilane as an endcapping reagent for decreasing residual silanol group on the surface of silica gel, and then introducing L-Pro as a chiral selector and hydrophobic octyl group to the silica gel surface simultaneously. The enantioseparations of 14 DL-amino acids on CSP1 were achieved with the enantioselectivity α ranging from 1.09 to 2.44 and the resolution Rs being between 0.8 and 6.3. The chromatographic performances of CSP1 with the bonded phase （CSP2） prepared using reference method were compared. The results showed that the column efficiency and resolution Rs of chiral stationary phase could be improved by using the above modifying method.

关键词： Ligand-exchange chromatography Chiral stationary phase Amino acids Enantiomeric resolution

Enantioseparation of Dencichine and D-Isomer on L-Cysteine Derivative Phase by Ligand-exchange Chromatography

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2006年第6期17卷 807-808页

作者： Yan Shun MA Qing Hua MENG hong yu shi yuan De LONG Tian Bao HUANG Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Graduate School of the Chinese Academy of Sciences Beijing 100049

The enantioseparation of dencichine and its D-isomer was achieved on a novel chiral stationary phase via coating N-（2-hydroxyl-3-octoxyl） propyl-S-benzyl-（L）-cysteine on YWG-C18 phase by ligand exchange chromatogr... 详细信息

关键词： Dencichine enantioseparation ligand exchange chromatography chiral stationaryphase.

MicroRNA changes of bone marrow-derived mesenchymal stem cells differentiated into neuronal-like cells by Schwann cell-conditioned medium

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第8期14卷 1462-1469页

作者： Zhi-Jian Wei Bao-You Fan Yang Liu Han Ding Hao-Shuai Tang Da-yu Pan Jia-Xiao shi Peng-yuan Zheng hong-yu shi Heng Wu Ang Li shi-Qing Feng Department of Orthopedics Tianjin Medical University General Hospital Tianjin China Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer Inst让ute Tianjin Medical University General Hospital Tianjin China Department of Orthopedics Henan Provincial People's Hospital Zhengzhou Henan Province China

Bone marrow-derived mesenchymal stem cells differentiate into neurons under the induction of Schwann cells. However, key microRNAs and related pathways for differentiation remain unclear. This study screened and identified differentially expressed microRNAs in bone marrow- derived mesenchymal stem cells induced by Schwann cell-conditioned medium, and explored targets and related pathways involved in their differentiation into neuronal-like cells. Primary bone marrow-derived mesenchymal stem cells were isolated from femoral and tibial bones, while primary Schwann cells were isolated from bilateral saphenous nerves. Bone marrow-derived mesenchymal stem cells were cultured in unconditioned (control group) and Schwann cell-conditioned medium (bone marrow-derived mesenchymal stem cell + Schwann cell group). Neuronal differentiation of bone marrow-derived mesenchymal stem cells induced by Schwann cell-conditioned medium was observed by time-lapse imaging. Upon induction, the morphology of bone marrow-derived mesencaymal stem cells changed into a neural shape with neurites. Results of quantitative reverse transcription-polymerase chain reaction revealed that nestin mRNA expression was upregulated from 1 to 3 days and downregulated from 3 to 7 days in the bone marrow-derived mesenchymal stem cell + Schwann cell group. Compared with the control group, microtubule-associated protein 2 mRNA expression gradually increased from 1 to 7 days in the bone marrow-derived mesenchymal stem cell + Schwann cell group. After 7 days of induction, microRNA analysis iden:ified 83 significantly differentially expressed microRNAs between the two groups. Gene Ontology analysis indicated enrichment of microRNA target genes for neuronal projection development, regulation of axonogenesis, and positive regulation of cell proliferation. Kyoto Encyclopedia of Genes and Genomes pathway analysis demonstrated that Hippo, Wnt, transforming growth factor-beta, and Hedgehog signaling pathv/ays were potenti

关键词： nerve regeneration microRNA analysis bone marrow-derived mesenchymal stem cells: Schwann cells neuronal-like cells neuronal differentiation Gene Ontology analysis Hippo signaling pathway Wnt signaling pathway transforming growth factor-beta signaling pathway Hedgehog signaling pathway neural regeneration

Effect of Patient Age and Embryo Parameters on Pregnancy Outcomein In Vitro Fertilization-Embryo Transfer(IVF-ET)

在线全文

学校读者我要写书评

暂无评论

Journal of Reproduction and Contraception 2010年第4期21卷 219-227页

作者： hong-zi DU Li LI Jian-qiao LIU Wen-hong ZHANG yu shi yu-ling HUANG Assisted Reproductive Department Institute of Obstetrics and Gynecology of the Third Affiliated Hospital of Guangzhou Medical College Guangzhou 510150 China

Objective To study the effect of patient age, the number and quality of embryos transferred on pregnancy outcome in in vitro fertilization-embryo transfer procedures （IVF-ETs）. Methods A retrospective study was conducted with infertile women who underwent a total of 1 800 cycles of lVF-ET and intracytoplasmic sperm injection （ICSI） at the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzhou Medical College from Jan. 2006 to Dec. 2007. The patients were divided into three groups based on age （year）. 〈30, 30-34 and 235. The rates of clinical pregnancy and multiple pregnancies were compared in each group when 1-3 embryos and 0-3 goodquality embryos were transferred respectively. Results 1） In the group of patients aged 〈30 years, there was no significant difference in pregnancy outcomes with 1-3 embryos transferred. However, pregnancy rates were similar when 2 3 good-quality embryos were transferred, which was significantly higher compared with 0-1 good-quality embryos transferred; the incidence of multiple pregnancies was not an issue when only 1 embryo was transferred. 2） The pregnancy rate of the patients aged 30 34 was not significant not only when only 2-3 embryos were transferred but also when 2-3 good-quality embryos were transferred, which was significant compared with when 1 embryo or 0 1 good-quality embryo was transferred. The subgroup of 3 good-quality embryos transferred, at the same time, was expected to significantly increase multiple pregnancy rate. 3） For the patients aged 235, there were similar pregnancy rates in the subgroup involving 1-3 embryos transferred. Compared with 0-2 good-quality embryos transferred, the pregnancy rate was significantly higher in the patients with 3 good-quality embryos transferred. An increased trend toward multiple pregnancies was observed among not only the subgroups with 1-3 embryos transferred, but also when 1-3 good-quality embryos were transferred, although it was significantly higher in patien

关键词： in vitro fertilization-embryo transfer (IVF-ET) embryo transfer (ET) age pregnancy rate multiple pregnancy rate

Profitable credit card business empirical analysis of factors

在线全文

学校读者我要写书评

暂无评论

Chinese Business Review 2009年第10期8卷 33-37,24页

作者： SHUAI Qing-hong shi yu-lu School of Economic Information Engineering Southwestern University of Finance and Economics Chengdu 610034 China

Since 1995, major domestic commercial banks are beginning to have a variety of credit cards issued. However, at present, China＇s relatively low profitability of the credit card business, it accounts for a smaller proportion of total bank income. By means of credit card revenue／cost structure analysis, the authors found spending and overdraft balances affecting credit card business, an important factor in profitability. At the same time, combined with a commercial bank＇s existing statistical data, using SPSS software correlation and regression analysis, the authors found that the key to improve the bank card revenue is to raise China＇s commercial banks, credit card revolving credit utilization, and expand the scale of overdraft balances.

关键词： credit card profit factor revenue/cost structure correlation

Morphology and molecular phylogeny of two colepid species from China, Coleps amphacanthus Ehrenberg, 1833 and Levicoleps biwae jejuensis Chen et al., 2016 （Ciliophora, Prostomatida）

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2016年第3期37卷 176-185页

作者： Bo-Rong LU Ming-Zhen MA Feng GAO yu-hong shi Xiang-Rui CHEN School of Marine Sciences Ningbo University Ningbo 315211 China Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao 266003 China

Two colepid ciliates, Coleps amphacanthus Ehrenberg, 1833 and Levicoleps biwae jejuensis Chen et al., 2016, were first recorded in China. Their living morphology, infraciliature and small subunit （SSU） rRNA gene sequences were determined using standard methods. The improved diagnosis of Coleps amphacanthus is as follows： cell size about 100x 50 pm in vivo, barrel-shaped; 22-28 ciliary rows each composed of about 14-21 monokinetids and two perioral dikinetids; 5-10 caudal cilia; and one terminal contractile vacuole. Levicoleps biwae jejuensis was also investigated, with an improved diagnosis given based on previous and present work. The phylogenetic analyses based on SSU rRNA gene sequences revealed that all Coleps species were grouped together, except for Coleps amphacanthus, which was grouped into a clade of the genus Levicoleps.

关键词： Ciliate Coleps Levicoleps New record Phylogeny SSU rRNA Taxonomy

Administration of imatinib in the first 90 days after allogeneic hematopoietic cell transplantation in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2011年第2期124卷 246-252页

作者： CHEN Huan LIU Kai-yan XU Lan-ping LIU Dai-hong CHEN yu-hong shi hong-xia HAN Wei ZHAN Xiao-hui WANG yu ZHAO Ting HUANG Xiao-jun Peking University Institute of Hematology Peking University People's Hospital Beijing 100044 China

Background Relapse happens frequently after allogeneic hematopoietic cell transplantation （alIo-HCT） in the patients with Philadelphia chromosome-positive acute lymphoblastic leukemia （Ph^＋ ALL）. Detection of the minimal residual disease （MRD） before and after alIo-HCT is associated with higher relapse rate. Early administration of imatinib after alIo-HCT may prevent recurrent Ph^＋ ALL. The aim of this study was to evaluate the safety and efficacy of imatinib in preventing hematological relapse when imatinib was administrated in the first 90 days after alIo-HCT. Methods Patients with Ph^＋ ALL that underwent alIo-HCT were enrolled in a prospective study. A TaqMan-based real-time quantitative polymerase chain reaction （RQ-PCR） technique was used to detect the MRD （bcr-abl transcript levels）. Imatinib therapy was initiated prior to 90 days after alIo-HCT if the patient＇s absolute neutrophil count （ANC） was above 1.0×10^9/L （without granulocyte colony-stimulating factor （G-CSF） administration） and the platelet count was greater than 50.0×10^9/L, or if the bcr-abl transcript levels were elevated in two consecutive tests, or if the bcr-abl transcript levels were 〉10.2 after the initial engraftment. The initial daily dose of imatinib was 400 mg/d for adults and 260 mg/m^2 for children （younger than 17 years）. Imatinib was administered for at least I month and the bcr-abl TaqMan results were negative for 3 consecutive tests, or complete molecular remission （CR^mol） was sustained for at least 3 months. Results From May 2005 to October 2008, 29 patients were enrolled in this study, of whom, 19 patients were male and 10 were female. The median age of the enrolled patients was 33 years （range 6-50 years）. Imatinib therapy was started at a median time of 60 days （range 20-122 days） post HCT （only one patient started Imatinib therapy at 122nd day after HCT）. Twenty-five adult patients could tolerate a dose of 300-400 mg/d of imatinib, and three children tolerated a dose of 260 mg

关键词： Philadelphia chromosome acute lymphoblastic leukemia allogeneic hematopoietic cell transplantation minimal residual disease