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Journal of Arid Land 2015年第2期7卷 264-271页

作者： hong xiang zhang Ming Li zhang Li Na WANG Key Laboratory of Biogeography and Bioresource in Arid Land Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences Institute of Botany Chinese Academy of Sciences Central China Normal University

Malus sieversii, a wild progenitor of domesticated apple, is distributed in western Xinjiang of China, eastern part of Kazakhstan and Kyrgyzstan in Central Asia. To well understand the genetic structure and the his- torical demography of this important germplasm resource, we sampled 15 populations with 110 individuals of Malus sieversii from the Yili Valley and the western mountains of the Junggar Basin, Xinjiang, and sequenced two nrDNA fragments for these 110 individuals. Meanwhile, we modeled and compared species distributions under the current and the Last Glacial Maximum climatic conditions. The results showed that populations of M. sieversfi from Xinjiang had low levels of genetic diversity and genetic differentiation. During the LGM period, populations of M. sieversfi had lost their northern distributions in the western mountains of the Junggar Basin. M. sieversfi has ex- perienced a demographic expansion from the south of the Yili Valley to the north of the western mountains of the Junggar Basin during the warm interglacial epochs. Due to the high sensibility of M. sieversii to disturbance, we proposed more attention should be paid to the M. sieversfi populations in the western mountains of the Junggar Basin.

关键词： Malus sieversii phylogeography LEAFY gene intron 1 species distribution modeling genetic diversity

Helicobacter pylori infection in the pharynx of patients with chronic pharyngitis detected with TDI-FP and modified Giemsa stain

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World Journal of Gastroenterology 2006年第3期12卷 468-472页

作者： Jiang-Ping zhang Zhen-Hui Peng Ju zhang xiang-hong zhang Qing Yin Zheng Department of Otolaryngology Second Hospitalof Xi'an Jiaotong University Xi'an 710004 Shaanxi ProvinceChina Institute of Genic Diagnosis Fourth Military MedicalUniversity Xi'an 710032 Shaanxi Province China The Jackson Laboratory 600 Main Street BarHarbor ME 04609 United States

AIM： To detect whether there is Helicobacter pylori （Hpylori） colonization in the pharynx mucous membrane of healthy people and whether chronic pharyngitis is related to Hpylori infection. METHODS： Fifty cases of chronic pharyngitis refractory over three months were prospectively studied from March 2004 to August 2004 in the otolaryngology outpatient department of the Second Hospital of Xi＇an Jiaotong University. Template-directed dye-terminator incorporated with fluorescence polarization detection （TDI-FP） and modified Giemsa stain were used to examine pharynx mucous membrane tissue for H pylori colonization in the patients with chronic pharyngitis and the healthy people as a control group. RESULTS： In the control group, no people were detected to have Hpylori in the pharynx. In contrast, in 50 cases with chronic pharyngitis, 19 （38.0%） cases were H pylori positive with a TDI-FP assay and 4 （8%） cases were TDI-FP positive with Giemsa staining in the pharynx. Sixteen of the 50 pharyngitis cases had stomach ailment history, 11 cases （68.8%） of these 16 patients were determined to be H pylori positive in the pharynx with the TDI-FP assay. 2,2 test showed that this infection rate was remarkably higher （P= 0.0007） than that in the cases without stomach ailment history. Giemsa staining showed that 3 cases （18.8%） of the patients with stomach ailment history were infected with H pylori in the pharynx, which was remarkably higher （P = 0.042） than that in the patients without stomach ailment history （1 case, which was 2.9%）. CONCLUSION： H pylori may not be detected in the pharynx of healthy people. Chronic pharyngitis may be related to H pylori infection. The infection rate with Hpylori in the pharynx is higher in patients with stomach ailment histories than in patients without stomach ailment histories, suggesting that chronic pharyngitis may be related to stomach ailment history.

关键词： Chronic pharyngitis H pylori Modified Giemsa stain

Glomus tumor of the gastric body:helical CT findings

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Chinese Medical Journal 2007年第14期120卷 1289-1291页

作者： HU Xiao-yun HU Chun-hong FANG xiang-ming zhang Tong-hua Medical Imaging Center First Affiliated Hospital Soochow University Suzhou 215006 China

Glomus tumors, also known as glomangiomas, are rare and originate in the neuromyoarterial glomus, a normal arteriovenous shunt which is abundantly supplied with nerve fibers and fulfills a temperature-regulating function. The classic location of glomus tumor is the subungual region, but the tumor can occur elsewhere in the skin, soft tissues, nerves, stomach, nasal cavity, and *** the gastrointestinal （GI） tract the tumor occurs more often in the stomach than other parts, and typically occurs as a solitary submucosal nodule in the antrum. We reported a case of glomus tumor originating from the greater curvature of stomach which was studied with contrast-enhanced helical computed tomography （CT） and described the characteristic helical CT findings of the rare lesion.

关键词： glomus tumor computed tomography diagnostic imaging

Discovery of and Preliminary studies on a Rapid-Leafing Rice Genotype at the Vegetative Growth Stage

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Rice science 2008年第1期15卷 29-35页

作者： MAO Hai-yan PAN Cun-hong CHEN Zong-xiang zhang Ya-fang Zuo Shi-min CHENG Jin-rong PAN Xue-biao Key Laboratory of Crop Genetics and Physiology of Jiangsu Province~Key Laboratory of Plant Functional Genomics of Ministry ofEducation of China Yangzhou University Yangzhou 225009 China

The leafing rates of fourteen rice varieties were measured in a sowing-time experiment, and a rapid leafing genotype at the vegetative growth stage was discovered in an indica variety Yanhui 559. The leaf number on the main culm of Yanhui 559 was always 4-5 leaves more than that of Lemont, and the leafing rate of Yanhui 559 was significantly higher than that of Lemont based on similar growth durations from sowing to heading. Furthermore, the difference of the leafing rate was significant at the vegetative growth stage, but not distinctive at the panicle initiation stage. Genetic analysis of the leafing rates in the two backcross populations of Yanhui 559 and Lemont showed that major and quantitative genes controlled the expression of rapid leafing character. Based on results of investigation for some plants with similar growth durations in the backcrossing populations, the rapid leafing genotypes exhibited earlier tillering and more tiller numbers per plant, and its yield components including the number of panicles per plant and number of grains per panicle were superior to those of the slow leafing genotypes. Further research and application feasibility of the rapid leafing genotype in breeding were discussed.

关键词： rapid leafing vegetative growth stage leaf number on the main culm number of panicles per plant rice

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中浓纸浆泵内部气液分离数值模拟与试验

排灌机械工程学报 2017年第4期35卷 309-318页

作者：叶道星李红张翔西华大学流体及动力机械教育部重点实验室四川成都610039 江苏大学国家水泵及系统工程技术研究中心江苏镇江212013

为了研究中浓纸浆泵内部的气液分离特征,基于欧拉-欧拉多相流模型,对泵内的流动进行三维非定常数值模拟,分析了转速、抽气真空度和流量对气液分离的影响及瞬态气液分离过程.搭建了基于声呐流量计的泵性能测试系统,研究了中浓纸浆泵运行... 详细信息

为了研究中浓纸浆泵内部的气液分离特征,基于欧拉-欧拉多相流模型,对泵内的流动进行三维非定常数值模拟,分析了转速、抽气真空度和流量对气液分离的影响及瞬态气液分离过程.搭建了基于声呐流量计的泵性能测试系统,研究了中浓纸浆泵运行性能特点.结果表明:随着转速的增大,较高的气体体积分数区域集中于湍流发生器叶片的背面,叶轮内的气体含量减小;随着流量的增大,湍流发生器内气体体积分数较高的区域面积逐渐减小,大流量工况下气体集聚在湍流发生器的背叶片根部.叶轮背面叶片的作用使气液得到了进一步的分离;转速、抽气真空度和流量的增大可以提高叶轮的气液分离能力.叶轮的排气孔附近产生并聚集了大量气体,并伴随着强烈的气液两相流相互作用变化.通过中浓纸浆泵的性能试验研究,发现提高泵的转速和抽气真空度有利于泵内的气液分离,验证了采用数值模拟方法研究中浓纸浆泵内部气液分离的正确性.研究气液分离特征有助于认识中浓纸浆泵内部气液分离过程的演变机理,为中浓纸浆泵的气液分离结构和排气系统提供设计参考.

关键词：中浓纸浆泵气液分离多相流数值模拟试验验证

Resistance to apoptosis should not be taken as a hallmark of cancer

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Chinese Journal of Cancer 2014年第2期33卷 47-50页

作者： Rui-An Wang Zeng-Shan Li Qing-Guo Yan Xiu-Wu Bian Yan-Qing Ding xiang Du Bao-Cun Sun Yun-Tian Sun xiang-hong zhang Department of Pathology The Fourth Military Medical University Department of Pathology The Third Military Medical University Department of Pathology Nanfang Medical University Department of Pathology Fudan University Department of Pathology Tianjin Medical University Department of Pathology Cancer Hospital of Chinese Academy for Medical Sciences Department of Pathology Hebei Medical University

In the research community, resistance to apoptosis is often considered a hallmark of cancer. However, pathologists who diagnose cancer via microscope often see the opposite. Indeed, increased apoptosis and mitosis are usually observed simultaneously in cancerous lesions. Studies have shown that increased apoptosis is associated with cancer aggressiveness and poor clinical outcome. Furthermore, overexpression of Bcl-2, an antiapoptotic protein, is linked with better survival of cancer patients. Conversely, Bax, CD95, Caspase-3, and other apoptosis-inducing proteins have been found to promote carcinogenesis. This notion of the role of apoptosis in cancer is not new; cancer cells were found to be short-lived 88 years ago. Given these observations, resistance to apoptosis should not be considered a hallmark of cancer.

关键词：癌症患者抗凋亡蛋白 Caspase-3 抗细胞凋亡 Bcl-2蛋白 Bax蛋白有丝分裂过度表达

Optimizing the Ex-post Trading Profits in a Financial Market

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运筹学学报 1997年第1期1卷 2-13页

作者： KIN LAM（Department of Finance and Decision Sciences, School of Business, hong Kong Baptist University, hong Kong) xiang-SUN zhang(Institute of Applied Mathematics, The Chinese Academy of Sciences, Beijing, China) WEI LI（Department of Finance and Decisi 香港浸会大学香港中科院应用数学所北京

Consider investing in an asset in a financial market. Given the investment returnri in day i, consider the problem of making an investmeat decision di in day i wheredi= 1,0, -1, has the meaning that the investor maintains a long, neutral or shortposition of the asset. The overall invest return over an n day period is given bywhere c=transaction cO8t and d0 = dn+1 = 0 are given. The optinization problemof maximizing IR(d) is considered. Analytic solution of the opthaation porblem isobtained. The solution is shown to be closely related to Alexander’s tilter trading ruleand has praCtical implication in applying neural network to generate trading signals ina financial maket.

关键词： filter trading rule optimization finance investment neural network training set

Serum Hormone and Cellular Proliferation Changes of Testis in Rats with Experimental Orchitis Induced by Lipopolysaccharide

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Journal of Reproduction and Contraception 2007年第3期18卷 181-186页

作者： Li-ying XUE xiang-hong zhang Ling-xiao XING Jie LI Geng-xin WANG Hebei Medical University Shijiazhuang 050011 China Hebei Provincial People＇s Hospital Shijiazhuang 050051 China

Objective To explore the changes of serum male hormone, androgen binding protein （ABP） expression as well as the proliferation of testicular cells in rats with experimental orchitis induced by bacterial lipoplysaccharide （LPS） in vivo and to elucidate the putative mechanism of LPS on spermatogenesis of testis. Methods The serum testosterone （T）, luteinizing hormone （LH） levels were detected with magnetic enzyme immunoassay. The expression of proliferating cell nuclear antigen （PCNA） and ABP expression at mRNA level of testis were studied with immunohistochemical staining and in situ hybrydization respectively. Results The serum T level in rats with experimental orchitis was significantly higher than that in the rats of control （P〈0.05） and ABP mRNA expression in Sertoli cells of testis was significantly increased （P〈0.05） while PCNA expression in seminiferous epithelium in experimental rats significantly was decreased as compared with that of the control （P〈0.05）. No significant change in serum LH level was seen between experimental orchitis and control groups （P〉0. 05）. Conclusion The serum level of T and ABP expression significantly increased in rats with experimental aspecific orchitis induced by LPS, and at the same time inhibition of cellular proliferation of seminiferous epithelium can be detected, which may be the possible mechanism of male infertility in inflammatory process.

关键词： orchitis LPS PCNA ABP testosterone

Quantum public-key crypto via EPR pairs

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 58-63页

作者： xiang-Qun Fu hong-Wei Li Jian-hong Shi Tan Li Wan-Su Bao Henan Key Laboratory of Quantum Information and Cryptography Information Engineering University Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China

With the development of quantum computing technology, quantum public-key cryptography is gradually becoming an alternative to the existing classical public-key cryptography. This paper designs a quantum trapdoor one-way function via EPR pairs and quantum measurements. Based on this, a new quantum public-key cryptosystem is presented, which offers forward security,and can resist the chosen-plaintext attack and chosen-ciphertext attack. Compared with the existing quantum public-key cryptos,eavesdropping can be automatically detected in this new quantum public-key cryptosystem under a necessary condition, which is also detailed in the paper.

关键词： quantum public-key crypto trapdoor one-way function EPR pairs

空气污染对劳动力供给的影响效应研究——理论分析与实证检验

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软科学 2017年第3期31卷 99-102,144页

作者：徐鸿翔张文彬西安交通大学经济与金融学院西安710061 西安财经学院经济学院西安710100

通过构建研究空气污染影响劳动力供给的局部均衡模型,理论分析表明,改善空气质量对劳动力供给时间的影响取决于"收入效应"和"替代效应"的权衡,但一般情况下后者占主导作用,空气污染还会通过对劳动生产率产生影响间接影响劳动力供给。随... 详细信息

通过构建研究空气污染影响劳动力供给的局部均衡模型,理论分析表明,改善空气质量对劳动力供给时间的影响取决于"收入效应"和"替代效应"的权衡,但一般情况下后者占主导作用,空气污染还会通过对劳动生产率产生影响间接影响劳动力供给。随后实证分析空气污染状况对劳动力供给的直接影响和通过影响劳动收入水平和劳动生产率对劳动力供给的间接影响,结果表明,空气污染的替代效应大于收入效应,空气污染会通过直接效应和间接效应双重途径降低劳动力供给。最后提出抑制空气污染对劳动力供给影响的政策建议。

关键词：空气污染劳动供给,局部均衡模型劳动生产率