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Chinese Chemical Letters 2006年第6期17卷 714-716页

作者： Shu Tao ma hong xiang LOU School of Pharmacy Shandong University Jinan 250012

Novel ethyl 7-chloro-6-fluoro-l-methyl-4-oxo-1, 4-dihydro-[1, 3]thiazeto[3, 2-a]quino- line-3-carboxylate 2 was prepared from 3-chloro-4-fluoroaniline in eight steps. It can be used as a new intermediate for the synth... 详细信息

关键词： Synthesis tricyclic fluoroquinolone.

Comparisons of{100}texture improvement and formability in hot-rolled non-oriented electrical steel by austenite-ferrite phase transformation and shear deformation

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Journal of Iron and Steel Research International 2025年第1期32卷 171-185页

作者： Chi-hao Yu hong-jiang Pan Yan-ping Zhao De-ting Tang Hai-jun Wang Faculty of materials Science and Engineering Kunming University of Science and TechnologyKunming650093YunnanChina School of Electronics and Information Engineering Anshun UniversityAnshun561000GuizhouChina School of Metallurgical Engineering Anhui University of TechnologyMa’anshan243032AnhuiChina

Over the years,the high magnetic induction of industrial Mn-added electrical steel is assumed to be the enhancement of{100}texture derived from its austenite-ferrite phase transformation during hot rolling(phase transformation(PT)method).However,it is still undetermined without straightforward experimental *** reason for{100}texture improvement of Mn-added electrical steel is experimentally confirmed due to the recrystallization induced by the austenite-ferrite phase transformation during hot ***,a more promising methodology to further improve{100}texture and formability of hot-rolled electrical steel is promoted by the control of hot rolling deformation condition(shear deformation(SD)method).The results show that the nucleation mechanisms of{100}oriented recrystallized grains are different in the samples by SD and PT methods,which are in-depth shear deformation and austenite-ferrite phase transformation,*** this case,coarse{100}oriented recrystallized grains and low residual stress are obtained in the sample by SD method,which is responsible for its superior{100}texture and *** contrast,the sample by PT method forms fine recrystallized grains with random orientations and accumulates severe residual stress.

关键词： Non-oriented electrical steel {100}texture Formability Austenite-ferrite phase transformation Shear deformation

Mechanism analysis of effect of MgO on reduction swelling behaviour of iron pellets in CO/H_(2)atmosphere based on first-principles calculations

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Journal of Iron and Steel Research International 2025年第1期32卷 73-84页

作者： hong-ming Long Jing-shu An Xing-wang Li Ting Wu Sheng-ping He Jie Lei School of Metallurgical Engineering Anhui University of TechnologyMa’anshan243032AnhuiChina Key Laboratory of Metallurgical Emission Reduction and Resource Comprehensive Utilization(Anhui University of Technology) Ministry of EducationMa’anshan243002AnhuiChina College of materials Science and Engineering Chongqing UniversityChongqing400044China

To explain the influence mechanism of MgO on the consolidation and reduction characteristics of roasted iron pellets,the properties and structure of pellets were investigated from *** indicated that the MgO addition decreased the reduction swelling index(RSI)and reduction degree of pellets in both CO and H_(2)*** the stepwise reduction process of Fe2O3→Fe3O4→FeO,the reduction behaviour of pellets in CO and H_(2)was similar,while the reduction rate of pellets in H_(2)atmosphere was almost twice as high as that in CO *** the stepwise reduction process of FeO→Fe,the RSI of pellets showed a logarithmic increase in CO atmosphere and a linear decrease in H_(2)*** investigated by first-principles calculations,C and Fe mainly formed chemical bonds,and the CO reduction process released energy,promoting the formation of iron ***,H and Fe produced weak physical adsorption,and the H_(2)reduction process was endothermic,inhibiting the generation of iron *** Mg2+doping in FexO,the nucleation region of iron whiskers expanded in CO reduction process,and the morphology of iron whiskers transformed from“slender”to“stocky,”reducing RSI of the pellets.

关键词： MgO CO atmosphere H_(2)atmosphere Reduction degree Reduction swelling index First-principles calculation

Acute Inflammatory Pain Induces Sex-different Brain Alpha Activity in Anesthetized Rats Through Optically Pumped magnetometer magnetoencephalography

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生物化学与生物物理进展 2025年第1期52卷 244-257页

作者： MIAO Meng-Meng REN Yu-Xuan WU Wen-Wei ZHANG Yu PAN Chen LIN xiang-hong LIN Hui-Dan CHEN Xiao-Wei Health Science Center Ningbo UniversityNingbo 315211China Department of Anesthesiology The First Affiliated Hospital of Ningbo UniversityNingbo 315000China Department of Pain The First Affiliated Hospital of Ningbo UniversityNingbo 315000China

Objective magnetoencephalography(MEG),a non-invasive neuroimaging technique,meticulously captures the magnetic fields emanating from brain electrical *** with MEG based on superconducting quantum interference devices(SQUID),MEG based on optically pump magnetometer(OPM)has the advantages of higher sensitivity,better spatial resolution and lower ***,most of the current studies are clinical studies,and there is a lack of animal studies on MEG based on OPM ***,a multifaceted sensory and emotional phenomenon,induces intricate alterations in brain activity,exhibiting notable sex *** clinical revelations of pain-related neuronal activity through MEG,specific properties remain elusive,and comprehensive laboratory studies on pain-associated brain activity alterations are *** aim of this study was to investigate the effects of inflammatory pain(induced by Complete Freund’s Adjuvant(CFA))on brain activity in a rat model using the MEG technique,to analysis changes in brain activity during pain perception,and to explore sex differences in pain-related MEG *** This study utilized adult male and female Sprague-Dawley *** pain was induced via intraplantar injection of CFA(100μl,50%in saline)in the left hind paw,with control groups receiving *** behavior was assessed using von Frey filaments at baseline and 1 h *** MEG recording,anesthetized rats had an OPM positioned on their head within a magnetic shield,undergoing two 15-minute sessions:a 5-minute baseline followed by a 10-minute mechanical stimulation *** analysis included artifact removal and time-frequency analysis of spontaneous brain activity using accumulated spectrograms,generating spectrograms focused on the 4-30 Hz frequency *** MEG recordings in anesthetized rats during resting states and hind paw mechanical stimulation were compared,before and after saline/CFA *** stimulation

关键词： magnetoencephalography pain sex differences alpha activity inflammation

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人口流动与媒体宣传对病毒传播的影响研究

管理科学学报 2025年第2期28卷 50-63页

作者：马英红李然刘伦山东师范大学商学院济南250014

流行性病毒的传播严重影响着人类的生命健康和社会经济的发展.如何控制病毒传播是社会各界共同关注的问题.在与刚过去的一场流行病传播的斗争中,人们通过宣传普及病毒知识和防护措施、精准调控人口流动,有效地遏制了病毒传播,保障了人... 详细信息

流行性病毒的传播严重影响着人类的生命健康和社会经济的发展.如何控制病毒传播是社会各界共同关注的问题.在与刚过去的一场流行病传播的斗争中,人们通过宣传普及病毒知识和防护措施、精准调控人口流动,有效地遏制了病毒传播,保障了人类生命安全.本研究梳理了病毒传播的相关数据,将病毒传播发展过程划分为三个阶段,充分考虑密切接触者和潜伏者作为病毒传播的重要环节,扩展经典的病毒传播状态转移模式,探讨人口流动、媒体宣传对病毒传播的影响机制,提出了出行管控和媒体宣传联合作用的病毒传播动力学方程.从数值仿真和拟合角度证明了适度的媒体宣传和人口流动管控有利于快速降低病毒传播的影响.

关键词：病毒传播数据分析动力学方程控制策略

基于分子束外延技术可控制备Bi原子团簇的研究

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原子与分子物理学报 2025年第2期42卷 79-84页

作者：马玉麟郭祥丁召贵州大学大数据与信息工程学院贵阳550025 贵州省微纳电子与软件技术重点实验室贵阳550025 半导体功率器件可靠性教育部工程研究中心贵阳550025

本研究基于分子束外延(MBE)技术在Si(111)衬底表面成功制备金属Bi原子团簇.首先,分别在100℃、125℃、150℃、175℃、200℃的生长温度下,制备了大小均一、密度不同的Bi原子团簇.实验结果表明,可以通过改变生长温度来精细控制Bi原子团簇... 详细信息

本研究基于分子束外延(MBE)技术在Si(111)衬底表面成功制备金属Bi原子团簇.首先,分别在100℃、125℃、150℃、175℃、200℃的生长温度下,制备了大小均一、密度不同的Bi原子团簇.实验结果表明,可以通过改变生长温度来精细控制Bi原子团簇的密度,当温度升高100℃,密度从1.05×10^(11)cm^(-2)降低至2.5×10^(7)cm^(-2),实现对团簇密度4个数量级的可控调节,并且发现Bi原子团簇密度对生长温度的依赖性符合经典成核理论.其次,分别在10 s、15 s、20 s的沉积时长下,制备了密度相同、尺寸各异的Bi原子团簇.实验结果表明,可以通过改变沉积时长来精细控制Bi原子团簇的尺寸:当沉积时长增加10 s,高度和直径分别从8.5 nm和65 nm增大到13.7 nm和100 nm,实现对团簇尺寸在10 nm高度、80 nm直径范围的可控调节,并且发现Bi原子团簇尺寸对沉积时长的依赖性符合晶体生长动力学.与分子束外延制备传统的Ⅲ族(Al,Ga,In)原子团簇做对比,这些结果可以为制备Ⅴ族原子团簇提供实验参考和指导,从而促进纳米级含Bi材料的制备.

关键词：分子束外延 Bi原子团簇生长温度沉积时长经典成核理论晶体生长动力学

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基于分子束外延技术可控制备Ga原子团簇的研究

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原子与分子物理学报 2025年第3期42卷 77-84页

本研究基于分子束外延(Molecular Beam Epitaxy,MBE)技术在Si(100)衬底表面成功制备金属Ga原子团簇.通过控制变量法,研究其尺寸形貌与工艺参数之间的关系.第一组对照实验分别在940℃、970℃、1000℃的Ga源温度下制备Ga原子团簇.实验结... 详细信息

本研究基于分子束外延(Molecular Beam Epitaxy,MBE)技术在Si(100)衬底表面成功制备金属Ga原子团簇.通过控制变量法,研究其尺寸形貌与工艺参数之间的关系.第一组对照实验分别在940℃、970℃、1000℃的Ga源温度下制备Ga原子团簇.实验结果表明,Ga源温度的升高导致Ga的蒸发量增加,进而沉积在Si衬底表面的Ga原子增多,Ga原子自组装成团簇,最终表现为Ga原子团簇的高度升高.第二组对照实验分别在3 s、6 s、10 s、40 s、50 s、60 s的沉积时长下制备Ga原子团簇.实验结果表明,沉积时长增加导致团簇的高度逐渐增加,主要由新吸附原子和竞争效应驱动.第三组对照实验分别在0 s、60 s、300 s的退火时长下制备Ga原子团簇.实验结果表明,退火时长的增加导致团簇的高度下降和团簇内的原子重新排列和分布有关.第四组对照实验分别在420℃、500℃的退火温度下制备Ga原子团簇.实验结果表明,升温至500℃退火会促进Ga原子团簇呈现有序排列,是表面原子的热运动和Ga原子团簇与Si(100)的晶格匹配度的共同作用的结果.

关键词： MBE Ga原子团簇 Ga源温度沉积时长退火时长

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学科实践的感性活动基础与育人价值实现

内蒙古社会科学 2025年第1期46卷 175-182,F0003页

作者：郭元祥马晓华华中师范大学教育学院湖北武汉430079

感性关涉人对外部世界的反映以及人的活动和存在方式,它既指感性认识,也指人的主观感受能力,更指实践的感性活动。人的完整性在于其实践性,形成于实践的感性活动,实践体现了感性的核心要义。学科实践是感性学习活动与理性学习活动的深... 详细信息

感性关涉人对外部世界的反映以及人的活动和存在方式,它既指感性认识,也指人的主观感受能力,更指实践的感性活动。人的完整性在于其实践性,形成于实践的感性活动,实践体现了感性的核心要义。学科实践是感性学习活动与理性学习活动的深度融合,它在本质上是以学科为载体、面向感性的现实世界、运用学科知识解决真实问题的实践活动。学科实践具有深刻的感性活动基础:其一,学科实践是认识性实践与改造性实践的统一;其二,作为学科实践主体的学生是具有感性意识和感性需要的感性存在;其三,学科实践是学生以外部世界和自我为对象的感性活动。深化实践育人,要求回应学科实践的感性活动基础。由感性直观到感性实践,确立学科实践的感性表达;超越知识符号,促进学生面向现实世界的学习;发展思维,实现感性认识向理性认识的转化;设计多样化的学科或跨学科的感性活动,丰富学生的主体经验。

关键词：学科实践感性活动感性与理性教学改革

Gut microbiota in cancer initiation,development and therapy

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Science China Life Sciences 2025年

作者： Ruyi Zhang xiang Zhang Harry Cheuk Hay Lau Jun Yu Institute of Digestive Disease and Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong Kong

Cancer has long been associated with genetic and environmental factors,but recent studies reveal the important role of gut microbiota in its initiation and *** 13%of cancers are linked to infectious agents,highlighting the need to identify the specific microorganisms *** microbiota can either promote or inhibit cancer growth by influencing oncogenic signaling pathways and altering immune *** can lead to cancer,while certain probiotics and their metabolites may help reestablish microecological balance and improve anti-tumor immune *** into targeted approaches that enhance therapy with probiotics is ***,the effects of probiotics in humans are complex and not yet fully ***,methods to counteract harmful bacteria are still in *** clinical trials also indicate that modifying gut microbiota may help manage side effects of cancer *** research is crucial to understand better how gut microbiota can be used to improve cancer prevention and treatment outcomes.

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基于特征模态分解及多尺度模糊散布熵的滚动轴承故障诊断

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科学技术与工程 2025年第1期25卷 176-185页

作者：梁翔宇胡业林马向阳宋晓安徽理工大学电气与信息工程学院淮南232000

针对复杂环境下的滚动轴承故障信息有效提取与辨识问题,提出一种基于特征模态分解(feature mode decomposition,FMD)及多尺度模糊散布熵(multiscale fuzzy dispersion entropy,MFDE)和斑马优化算法(zebra optimization algorithm,ZOA)优化支持向量机的滚动轴承故障诊断方法。为了解决FMD中关键参数不具有自适应性这一问题,以最小包络熵作为目标函数,采用白鲸优化算法(beluga whale optimization,BWO)优化FMD寻找最优参数组合,实现对故障信号的最优分解;引入多尺度模糊散布熵构建分解后不同模态下的特征向量;最后,将特征向量输入支持向量机中进行训练和识别,通过公开数据集和自制实验平台数据集验证了提出方法的有效性。

关键词：特征模态分解多尺度模糊散布熵支持向量机滚动轴承故障诊断